Negative / Null Result ReportMedicine
Rozemeijer S, Dubois EA, de Grooth HJ et al. · 2026 · Intensive care medicine
Background Besides temperature management, there is currently no effective therapy to decrease the burden of post-cardiac arrest syndrome. The pleiotropic effects of vitamin C may improve clinical outcome. Purpose This trial investigated…
View details →DOI: 10.1007/s00134-026-08492-5 Negative / Null Result ReportMedicine
Martínez-Ocón J, Pérez M, Calvo A et al. · 2026 · Journal of clinical anesthesia
Background Sedation during endoscopic retrograde cholangiopancreatography procedures (ERCP) increases the risk of hypoxemia and the need for respiratory support in high-risk patients. High flow nasal cannula (HFNC) provides humidified gas…
View details →DOI: 10.1016/j.jclinane.2026.112189 Negative / Null Result ReportMedicine
Kashtiara A, Pauptit J, Thijs D et al. · 2025 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Objectives Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols may reduce pain, hospital length of…
View details →DOI: 10.1007/s00586-025-09640-z Negative / Null Result ReportMedicine
García-García M, Mosqueda J, Escobar Cabrera JE et al. · 2025 · Toxicon
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
Failed Experiment ReportOpen accessMedicine
Grover V, Acharya SR, Chatra A et al. · 2026 · BMC oral health
BACKGROUND: Resin-based composites (RBCs) are commonly used in restorative dentistry, but bleaching agents may compromise their mechanical integrity. The effect of in-office bleaching with 25% hydrogen peroxide (HP) on the flexural…
View details →DOI: 10.1186/s12903-026-08240-7 Negative / Null Result Report
Kashtiara A, Pauptit J, Thijs D et al. · 2025 · Preprint
Abstract BACKGROUND AND OBJECTIVES: Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols—termed…
View details →DOI: 10.21203/rs.3.rs-7786792/v1 Negative / Null Result ReportOpen accessMedicine
Muir KJ, Maye A, McHugh MD et al. · 2025 · JAMA network open
Importance It is unknown if virtual nursing (VN) enhances care quality or improves the workload of bedside nurses in hospitals. Objective To describe what services VNs provide to patients and nurses in hospitals; to evaluate whether the…
View details →DOI: 10.1001/jamanetworkopen.2025.45597 Negative / Null Result ReportOpen accessMedicine
Nakamura Y, Murata S, Yabe T et al. · 2026 · Cureus
Introduction C5 palsy is a disabling complication after posterior cervical decompression and fusion (PCDF). Whether C4/5 facetectomy reduces the incidence or improves the outcomes of C5 palsy remains uncertain. Therefore, this study aimed…
View details →DOI: 10.7759/cureus.109458 Negative / Null Result ReportMedicine
Kipper CW, Kis P, Burleson KN et al. · 2026 · European journal of applied physiology
Objective Exercise-induced muscle damage (EIMD) compromises neuromuscular function and reduces exercise tolerance. Whether muscle oxidative capacity (MOC), an index of mitochondrial function, is reduced by EIMD or influences neuromuscular…
View details →DOI: 10.1007/s00421-025-06073-w Negative / Null Result ReportMedicine
Valle-Cruz JA, Lopiz Y, Garríguez-Pérez D et al. · 2026 · International orthopaedics
Purpose Rotational instability is a key factor in fixation failure of extracapsular hip fractures. The U-Blade (RC) lag screw was designed to improve rotational stability. This study aimed to compare mechanical complication rates between…
View details →DOI: 10.1007/s00264-025-06714-x Negative / Null Result ReportMedicine
Wittberg DM, Admassu F, Aragie S et al. · 2026 · Tropical medicine & international health : TM & IH
Objectives Few randomised trials have been done to assess the impact of hygiene interventions on trachoma even though hygiene improvements feature prominently in the strategy for global elimination of trachoma. This study's aim was to…
View details →DOI: 10.1111/tmi.70086 Negative / Null Result ReportMedicine
Krzyżaniak M, Warmiński K, Olba-Zięty E et al. · 2025 · Industrial Crops & Products
Camelina sativa (L. Crantz) is an annual oilseed crop cultivated for industrial and food purposes. To expand camelina's cultivation area, improve yields, and reduce weed pressure, the crop can be grown in intercropping system. The aim of…
Negative / Null Result ReportMedicine
Perez-Valero I, Corona Mata D, Crussells Canales MJ et al. · 2026 · International journal of antimicrobial agents
Objective To evaluate if switching from dolutegravir/lamivudine (DTG/3TC) to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) improves neuropsychiatric tolerability in suppressed adults with stable neuropsychiatric…
View details →DOI: 10.1016/j.ijantimicag.2026.107825 Negative / Null Result ReportMedicine
Dodson JA, Adhikari S, Schoenthaler AM et al. · 2026 · Journal of the American College of Cardiology
Background Nonadherence to antihypertensive medications is common. Mobile health (mHealth)-based behavioral economic interventions may improve adherence, but remain largely untested, especially in vulnerable populations. Objective The…
View details →DOI: 10.1016/j.jacc.2025.10.062 Negative / Null Result ReportOpen accessMedicine
Gulersen M, Berghella V, Bornstein E · 2025 · Journal of clinical medicine
Singleton pregnancies complicated by a short cervical length (≤25 mm) are at significantly increased risk for spontaneous preterm birth. Several treatment strategies aimed at reducing this risk and improving perinatal outcomes have been…
View details →DOI: 10.3390/jcm14155544 Negative / Null Result ReportMedicine
Cancellier EL, Degryse F, da Silva RC et al. · 2025 · The Science of the total environment
The use of petroleum-based coatings in controlled-release fertilizers (CRFs) raises environmental concerns and it is unclear if, and to what extent, CRFs can improve P use efficiency. This study explored the synthesis of bio-based…
View details →DOI: 10.1016/j.scitotenv.2025.180403 Negative / Null Result ReportMedicine
Elzawahry S, Elhilali H, Awadein A et al. · 2026 · Journal of pediatric ophthalmology and strabismus
Purpose To investigate whether using an enhanced monofocal intraocular lens (IOL) in the pediatric age group can improve the visual performance at varying distances in comparison to standard monofocal lenses. Methods Forty-five eyes of…
View details →DOI: 10.3928/01913913-20250530-03 Negative / Null Result ReportOpen accessMedicine
Alarifi M, Luo J, Jabour A et al. · 2026 · Journal of clinical medicine
Background/Objectives : Immediate patient access to radiology reports has increased the need for communication that patients can understand, yet it remains unclear whether simplifying report language improves comprehension without…
View details →DOI: 10.3390/jcm15114158 Negative / Null Result ReportMedicine
Nageswaran S, Easterling D, Skaar JE et al. · 2025 · Pediatrics
Background and objectives Improving home health (HH) care for children with medical complexity (CMC) is critical. We developed ICollab, a care model involving collaboration between a children's hospital's complex care clinicians, HH…
View details →DOI: 10.1542/peds.2024-070454 Negative / Null Result ReportMedicine
Nahmias J, Stopenski S, Jebbia M et al. · 2025 · JAMA surgery
Importance Traumatic rib fractures are associated with significant morbidity, including pulmonary complications and prolonged opioid use. Identifying adjunctive treatments that can reduce opioid consumption without compromising safety…
View details →DOI: 10.1001/jamasurg.2025.3221 Negative / Null Result ReportMedicine
Wynberg E, Mishra A, Liverani M et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Poorly targeted antibiotic use in primary care is a driver of antimicrobial resistance. Electronic clinical decision support algorithms (eCDSAs) integrating point-of-care tests may improve prescribing. We evaluated the impact of…
View details →DOI: 10.1016/j.ijid.2026.108382 Negative / Null Result ReportMedicine
Griffin AJ, Jungers JM · 2025 · Field Crops Research.
Intermediate wheatgrass (Thinopyrum intermedium; IWG) is a perennial, cool-season grass undergoing domestication as a grain and forage crop. Intercropping perennial legumes with IWG could reduce synthetic N fertilizer inputs, improve…
Negative / Null Result ReportMedicine
Moraes LGDS, Oliveira VC, Macedo AP et al. · 2025 · The International journal of prosthodontics
Purpose To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus,…
View details →DOI: 10.11607/ijp.9133 Negative / Null Result ReportMedicine
García-García M, Mosqueda J, Escobar-Cabrera JE et al. · 2025 · Toxicon : official journal of the International Society on Toxinology
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
View details →DOI: 10.1016/j.toxicon.2025.108543 Negative / Null Result Report
Belak L, James K, Auguste L et al. · 2026 · Preprint
ABSTRACT Background Hypertension is a leading modifiable cardiovascular risk factor prominently influenced by health-related social needs (HRSN). Whether detailed information on HRSN can improve identification of hypertension among…
View details →DOI: 10.64898/2026.06.12.26355558 Negative / Null Result ReportMedicine
Klaps S, Verbrugghe J, Goossens N et al. · 2026 · BMC sports science, medicine & rehabilitation
Background To compare the effects of a multimodal whole-body high-intensity training (HIT) program versus a moderate-intensity training (MIT) program on inspiratory muscle function in persons with chronic nonspecific low back pain…
View details →DOI: 10.1186/s13102-026-01773-y Negative / Null Result ReportMedicine
Benomar A, Fahed R, Omar AT et al. · 2026 · Journal of neurointerventional surgery
Background The Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography (CTA) Collateral Score (CS) are routinely used to estimate ischemic core burden and collateral status in acute ischemic stroke due to large vessel occlusion,…
View details →DOI: 10.1136/jnis-2026-025321 Negative / Null Result Report
Smith HJ, Delf B, Rosi V et al. · 2026 · Preprint
Artificial voices are encountered frequently in modern life, including artificial “clones” of an individual’s voice. For natural voices, familiar talkers are more intelligible than unfamiliar talkers when competing speech is present, which…
View details →DOI: 10.31234/osf.io/6bu8x_v1 Failed Experiment ReportMedicine
Anfosso M, Schubert M, Cremers JF et al. · 2026 · Andrology
Background Non-obstructive azoospermia (NOA) represents the most severe form of male infertility. Hypogonadism is common in NOA patients, and normal testosterone (T) levels are considered essential for spermatogenesis. Fertility-preserving…
View details →DOI: 10.1111/andr.70292 Negative / Null Result ReportOpen accessMedicine
Lee-Miller CA, Kairalla JA, Hibbitts E et al. · 2026 · Blood advances
Abstract Patients with central nervous system (CNS) disease at diagnosis on Children's Oncology Group (COG) B-acute lymphoblastic leukemia (B-ALL) trials AALL0331 and AALL0232 had inferior outcomes, largely secondary to CNS relapse. In…
View details →DOI: 10.1182/bloodadvances.2026019660 