Negative / Null Result ReportMedicine
Ansaloni LS, Domingues CEC, Gregori M et al. · 2026 · Insects
Given the current global agricultural system, honey bees are exposed to a complex network of stressors that can act simultaneously, making it challenging to maintain healthy colonies. Therefore, studies on natural products to improve…
View details →DOI: 10.3390/insects17060594 Replication FailureOpen accessMedicine
Ward E, Hanbury G, Possamai L et al. · 2025 · BMJ open quality
Background End-stage liver disease (ESLD) is a terminal diagnosis with a poor prognosis and an accelerating mortality rate in the UK. Limited research suggests that patients with ESLD have unmet palliative care (PC) needs, likely due to…
View details →DOI: 10.1136/bmjoq-2025-003521 Negative / Null Result Report
Li N, Wu C, Cao P et al. · 2023 · Preprint
Abstract Background: Rhodococcus equi is one of the most important causes of zoonotic infections from grazing animals. It poses a particular risk to immunocompromised individuals, including those who are undergoing long-term…
View details →DOI: 10.1099/acmi.0.000600.v3 Replication FailureOpen access
Panca M, Serfaty M, Satchell J et al. · 2025 · Preprint
Abstract Background : Crime has significant impact on older victims. High rates of anxiety and depression may be associated with crimes. Aims: This paper aims to evaluate the cost-effectiveness of a Victim Improvement Package (VIP) for the…
View details →DOI: 10.21203/rs.3.rs-7256160/v1 Negative / Null Result ReportOpen accessMedicine
Li J, Zhou J, Ha Q et al. · 2026 · Frontiers in cardiovascular medicine
Objective Obesity is an independent risk factor for cardiovascular diseases and elevated mortality, yet the underlying mechanisms remain incompletely understood. Impaired endothelium-dependent relaxation is an early manifestation of…
View details →DOI: 10.3389/fcvm.2026.1797300 Replication FailureMedicine
Moss AS, Nguyen QG, Iyer P · 2026 · Clinical rheumatology
Background Patient education materials are vital to health education and, according to the American Medical Association (AMA), should not be written above a 6th grade reading level (Weiss 2003). We aim to assess American College of…
View details →DOI: 10.1007/s10067-025-07746-9 Negative / Null Result ReportOpen accessMedicine
Beijer G, Swartling M, Nielsen EI et al. · 2025 · Critical care (London, England)
Background Standard dosing regimens of meropenem and piperacillin-tazobactam frequently fail to achieve targeted plasma concentrations in critically ill patients. Extended or continuous regimens are often used to improve target attainment.…
View details →DOI: 10.1186/s13054-025-05445-0 Negative / Null Result ReportMedicine
Jang S, Kim D, Kim T et al. · 2025 · Nanotechnology
In this study, a Cleaning Endpoint Evaluation Sensor (CEES) was developed and applied to improve the monitoring accuracy and uniformity control in the cleaning processes for NF 3 -based remote plasma sources in semiconductor equipment.…
View details →DOI: 10.1088/1361-6528/adf8f6 Negative / Null Result ReportOpen accessMedicine
Harada Y · 2026 · Cureus
Introduction Large language models are increasingly discussed as tools for patient-facing symptom assessment, but safe self-triage depends on the concrete next action recommended to the user rather than on generic urgency language alone.…
View details →DOI: 10.7759/cureus.105878 Negative / Null Result ReportOpen accessMedicine
Panzer S, Hofstetter N, Schreiber M et al. · 2026 · Experimental brain research
The present study examined if a daytime nap of 90 min can further improve skill memory afforded by observation and physical practice. Moreover, we determined if a 'nap' benefit was restricted to a particular representational form (spatial…
View details →DOI: 10.1007/s00221-026-07281-2 Failed Experiment ReportOpen accessMedicine
Srivastava S, Kharkar VR, More S et al. · 2024 · Journal of clinical and experimental dentistry
Background Absorbable gelatin sponges are able to reduce the incidence of post-extraction complications when soaked with antimicrobial agents. However, the drawbacks associated with the injudicious use of antibiotics warrant the need to…
View details →DOI: 10.4317/jced.61640 Negative / Null Result ReportMedicine
Pilas LB, Gur O, Berger G · 2023 · The Israel Medical Association journal : IMAJ
Background In the past decade, numerous new imaging and laboratory tests have been implemented that significantly contribute to improved medical diagnostic capabilities. However, inappropriate utilization, which occurs on a large scale,…
Negative / Null Result Report
Glanzer BM, Ladki MS, Chea M et al. · 2023 · Preprint
This study tests the utilization of Bluetooth noise-canceling headphones in improving the quality of eye exams in patients with hearing loss. University of Texas Medical Branch patients above 55 years of age were screened for hearing loss…
View details →DOI: 10.20944/preprints202310.1157.v1 Negative / Null Result ReportMedicine
Ahmadi Somaghian S, Pajouhi N, Dezfoulian O et al. · 2024 · Archives of physiology and biochemistry
Objective Improvement of cell survival is essential for achieving better clinical outcomes in stem cell therapy. We investigated the effects of hyperoxic pre-treatment (HP) on the viability of human adipose stromal stem cells (ASCs).…
View details →DOI: 10.1080/13813455.2023.2238918 Replication FailureOpen accessMedicine
Gangeri L, Alfieri S, Anselmi V et al. · 2025 · Tumori
Background As part of the improvement plan of the Organisation of European Cancer Institutes at the Fondazione IRCCS Istituto Nazionale dei Tumori of Milan (INT) a Committee composed of patients, caregivers, and representatives of patient…
View details →DOI: 10.1177/03008916251346564 Negative / Null Result ReportOpen accessMedicine
Kumar S, Kumar A, Ameta N et al. · 2026 · Annals of cardiac anaesthesia
Background In-hospital cardiac arrest demands immediate response to improve survival outcomes. The Code Blue Response System (CBRS) was designed to streamline emergency interventions by reducing response times. This study aimed to evaluate…
View details →DOI: 10.4103/aca.aca_102_25 Negative / Null Result ReportOpen accessMedicine
Minion S, Kiene J, Dellavalle R · 2023 · JMIR dermatology
Gender disparities exist across all facets of academic medicine including within the editorial boards of dermatology journals. Only 22% of these editorial boards comprised women, even though 51% of full-time, faculty dermatologists are…
View details →DOI: 10.2196/43256 Negative / Null Result Report
Holl CK, Bonilla Yanez M, Finley JM et al. · 2026 · Preprint
Background and Purpose Walking after stroke is often characterized by persistent biomechanical impairments and reduced walking capacity. While visual biofeedback can improve gait mechanics and fast walking can enhance capacity, it is…
View details →DOI: 10.64898/2026.06.08.26355006 Negative / Null Result ReportMedicine
Uyoga MA, Baumgartner J, Malan L et al. · 2026 · The Journal of nutrition
Background Young South African women face a double-burden of overweight or obesity and iron deficiency, with the former predicting the latter. Omega-3 long-chain polyunsaturated fatty acid (LCPUFA) supplementation can reduce inflammation.…
View details →DOI: 10.1016/j.tjnut.2025.101280 Negative / Null Result ReportMedicine
Quan S, Xie H, Zhang D et al. · 2026 · Esophagus : official journal of the Japan Esophageal Society
Background Postoperative chylothorax is a serious complication following esophagectomy. The efficacy of thoracic duct ligation (TDL) for chylothorax prevention is controversial. This study aimed to evaluate the impact of TDL on chylothorax…
View details →DOI: 10.1007/s10388-026-01219-x Negative / Null Result ReportMedicine
Hetherington A, Bauer L, Rablin S et al. · 2026 · Australasian emergency care
Background Acute wheeze is a common emergency department presentation among pre-school aged children. Innovative models of care that safely optimise treatment and streamline patient flow are needed. A nurse-led stretching of inhaled…
View details →DOI: 10.1016/j.auec.2026.05.001 Negative / Null Result ReportMedicine
Jdidi H, de Bisschop C, Dugué B et al. · 2026 · European journal of applied physiology
Purpose Whole-body cryostimulation (WBC) has recently been shown to improve autonomic nervous control of the cardiovascular system. This study aimed to investigate the acute and repeated effects of WBC on baroreflex sensitivity (BRS),…
View details →DOI: 10.1007/s00421-026-06261-2 Negative / Null Result ReportMedicine
Shaposhnikov MM, Trmcic A, Martin NH · 2026 · Journal of dairy science
The microbial quality of fluid milk is improved via processing steps, such as pasteurization which reduces the overall microbial population of milk and in particular is effective against Gram-negative, heat sensitive bacteria. Therefore,…
View details →DOI: 10.3168/jds.2026-28244 Negative / Null Result ReportMedicine
Sosnowski KJ, Ranse KL, Mitchell ML et al. · 2026 · Critical care medicine
Objectives To test whether the ABCDEF bundle, compared with usual care, decreases delirium incidence and duration, improves functional status in the ICU, and enhances 90-day post-ICU discharge quality of life in critically ill Australian…
View details →DOI: 10.1097/ccm.0000000000007154 Negative / Null Result ReportOpen accessMedicine
Jacquier M, Laroye C, Bensoussan D et al. · 2026 · Respiratory research
Background Although mesenchymal stromal cells (MSCs) have shown promising effects in preclinical pneumonia models, their ability to improve outcomes in ventilator-associated pneumonia (VAP) remains poorly explored, despite VAP being a…
View details →DOI: 10.1186/s12931-025-03457-6 Negative / Null Result ReportMedicine
Guo Y, Hu S, Wang Z et al. · 2026 · Journal of neurotrauma
The formation of brain edema is one of the key factors that determine patient outcomes following traumatic brain injury (TBI). Despite decades of research, no causal treatment is available to date. Among the many factors discussed,…
View details →DOI: 10.1177/08977151261451145 Negative / Null Result ReportMedicine
Khera P, Jain S, Khurana S et al. · 2026 · European journal of pediatrics
Surfactant replacement therapy improves outcomes in preterm neonates with respiratory distress syndrome (RDS). While the less invasive surfactant administration (LISA) technique offers advantages over intubate-surfactant-extubate (INSURE),…
View details →DOI: 10.1007/s00431-026-06904-8 Negative / Null Result Report
Snape D, Wainwright B, Parsons IT et al. · 2026 · Preprint
Short-term heat acclimation (HA) induces cardiovascular and fluid-regulatory adaptations, but it’s impact on markers of renal tubular injury and acute kidney injury risk (AKI) during exercise-heat stress remains unclear. Fourteen healthy…
View details →DOI: 10.64898/2026.03.06.710014 Negative / Null Result ReportMedicine
Ang D, Nathens A, Nayduch D et al. · 2026 · Annals of surgery
Objectives To evaluate whether surgical stabilization of rib fractures (SSRF) improves acute and patient-centered outcomes in adults with clinically significant rib fractures. Summary of background data Rib fractures occur in up to 40% of…
View details →DOI: 10.1097/sla.0000000000007053 Negative / Null Result ReportMedicine
Westerhout SF, Remmers S, Bangma CH et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Introduction Prostate-specific antigen (PSA)-based prostate cancer (PCa) screening can be improved by individualised, risk-stratified strategies. Comorbidity influences life expectancy, so may affect benefits of screening. We evaluated…
View details →DOI: 10.1016/j.ejca.2026.116741 