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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

730 results in Negative / Null Result Report for "aging" · page 25 of 25

Negative / Null Result ReportOpen accessMedicine

Development of Machine Learning Models to Predict Daily Gas Ebullition Flux in Waterways from Sediment Characteristics.

Mansouri M, Rockne KJ · 2026 · ACS environmental Au

Gas ebullition plays a critical role in facilitating contaminant transport from the sediment to the water column. Predicting gas ebullition accurately is necessary for managing sediments and assessing sediment/water flux, and many…

View details →DOI: 10.1021/acsenvironau.5c00221
Negative / Null Result ReportMedicine

Comparison of post-stroke white matter assessment using disconnectome-symptom mapping versus quantitative diffusion MRI.

Domin M, Liew SL, Hordacre B et al. · 2025 · NeuroImage

Indirect structural disconnection-symptom mapping allows white matter impairment to be determined without the need for multi-directional diffusion (MDDW) imaging for each individual. Although widely used this method has not been validated.…

View details →DOI: 10.1016/j.neuroimage.2025.121347
Negative / Null Result ReportOpen accessMedicine

Surveillance after treatment for head and neck cancer.

Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery

Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…

View details →DOI: 10.1097/moo.0000000000001102
Negative / Null Result ReportOpen accessMedicine

Analysing the clinical outcomes between FIGO 2009 and 2023 staging for endometrial cancer-a single institution retrospective study.

Vuppu DP, Rajanbabu A, Nair IR et al. · 2025 · Ecancermedicalscience

The latest International Federation of Gynaecology and Obstetrics (FIGO) staging for endometrial cancer incorporated molecular profiles and histopathological factors into the basic staging framework. This study was done to determine its…

View details →DOI: 10.3332/ecancer.2025.1836
Negative / Null Result ReportMedicine

Tumor-induced rickets/osteomalacia (TIO): diagnostic pitfalls and therapeutic options.

Ito N, Fukumoto S · 2025 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

A 10-year-old girl developed bilateral gonalgia and waddling gait. Biochemical and imaging studies showed hypophosphatemia with impaired proximal tubular phosphate reabsorption and high intact fibroblast growth factor 23 (FGF23) level,…

View details →DOI: 10.1093/jbmr/zjaf047
Negative / Null Result ReportOpen accessMedicine

Stable White Matter Structure in the First Three Years After Psychosis Onset.

Van Dyken PC, Yang K, Faria AV et al. · 2025 · Biological psychiatry global open science

Background White matter alterations observed using diffusion weighted imaging have become a hallmark of chronic schizophrenia, but it is unclear when these changes arise over the course of the disease. Nearly all studies reported to date…

View details →DOI: 10.1016/j.bpsgos.2025.100472
Negative / Null Result ReportOpen accessMedicine

Shedding light on public perceptions of scientists who engage in wrongness admission amidst a failed replication.

Evans ND, Fetterman AK · 2026 · Public understanding of science (Bristol, England)

Admitting that one's research findings are wrong involves admitting a potential instance of incompetence, which can keep scientists from engaging in wrongness admission. However, wrongness admission can yield favorable perceptions. In five…

View details →DOI: 10.1177/09636625251372820
Negative / Null Result Report

Is musical engagement enough to keep the brain young?

Matziorinis AM, Gaser C, Koelsch S · 2022 · Preprint

Music-making and engagement in music-related activities have shown procognitive benefits for healthy and pathological populations, suggesting reductions in brain aging. A previous brain aging study, using Brain Age Gap Estimation…

View details →DOI: 10.21203/rs.3.rs-1991605/v1