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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

698 results in Negative / Null Result Report for "aging" · page 23 of 24

Negative / Null Result ReportMedicine

Lumbar degenerative disease: association of serum complement levels with diagnosis, structural severity, and postoperative prognosis.

Deng, Zhu, Cao et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

The clinical evaluation of lumbar degenerative disease (LDD) severity relies on symptoms and imaging, lacking biologically specific diagnostic markers. This study investigated the role of serum complements in LDD to assess their potential…

View details →DOI: 10.1007/s00586-026-10086-0
Negative / Null Result ReportOpen accessPediatrics

Association between parental factors and child's behaviors during moderate sedation in pediatric dental care

Mohamad A. Alanbari, Mohamad A. Alanbari, Hebah M. Hamdan et al. · 2024 · Frontiers in Pediatrics

Background/AimManaging young children with negative behaviors can be challenging in dental settings. Moderate sedation (MS) is often used as a treatment option for such children. However, children's behavior during MS may vary depending on several variables. These variables include parental factors, such as parental anxiety, coping strategies, and pain catastrophizing. However, this area, particularly in Saudi Arabia, remains underexplored. Therefore, this study aimed to assess the association among parental anxiety, coping style, pain catastrophizing, and children's behavior during MS among S

View details →DOI: 10.3389/fped.2024.1456395
Negative / Null Result ReportOpen access

Pre-defoliation canopy height for signal grass ‘Basilisk’ in silvopastoral systems

V. Oliveira, R. B. D. Silva, A. Veloso et al. · 2024 · Semina: Ciências Agrárias

The objective of this study was to compare the response of Urochloa decumbens cv. Basilisk pastures in monoculture and silvopastoral systems (SPS), and to determine the most suitable pre-defoliation canopy height for managing this species…

View details →DOI: 10.5433/1679-0359.2024v45n4p1081
Negative / Null Result ReportOpen accessMedicine

Difference in Background Parenchymal Enhancement on Contrast-Enhanced Mammography in Treatment-Naïve Versus Systemic Neoadjuvant Chemotherapy Patients.

Hoon OH, Leung SY, Ko TY et al. · 2026 · Cureus

Background and purpose Contrast-enhanced mammography (CEM) has emerged as a valuable imaging modality for breast cancer detection and management. Background parenchymal enhancement (BPE) reflects the level of normal glandular tissue…

View details →DOI: 10.7759/cureus.107590
Negative / Null Result ReportMedicine

Exploring the Association of Religion and Religiosity on Mammography Screening Among White and Black Women: Results from the Brazilian Longitudinal Study of Aging (Elsi-Brazil).

Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health

This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…

View details →DOI: 10.1007/s10943-026-02694-3
Negative / Null Result ReportMedicine

The Association Between the STOP-Bang Score and the Integrated Pulmonary Index in Patients Undergoing Endobronchial Ultrasound with Sedation: The STOP OSA-IPI Cohort Study.

Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…

View details →DOI: 10.3390/medicina62061034
Negative / Null Result ReportMedicine

Magnetic resonance imaging-derived anterior tibial translation after anterior cruciate ligament reconstruction and its association with postoperative adverse events: A retrospective cohort study.

Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine

Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…

View details →DOI: 10.1016/j.jisako.2026.101134
Negative / Null Result ReportMedicine

FDG PET/CT imaging in recurrent papillary thyroid cancer: does BRAF mutation status matter?

Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...

Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…

View details →DOI: 10.23736/s1824-4785.26.03686-1
Negative / Null Result ReportOpen accessMedicine

Plantar Heel Pain Is Not Associated With Fatty Infiltration of the Abductor Digiti Minimi Muscle on Magnetic Resonance Imaging: A Cross-Sectional Observational Study.

Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research

Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…

View details →DOI: 10.1002/jfa2.70155
Negative / Null Result ReportMedicine

Relationship between <i>APOE</i> Genotype Status and Imaging Features in Patients with Alzheimer Disease Being Considered for Antiamyloid β Therapy.

Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology

Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…

View details →DOI: 10.3174/ajnr.a9056
Negative / Null Result ReportOpen accessMedicine

Assessment of Pulp-Tooth Ratio Based on 3D Segmentation for Age Estimation for Forensic Purposes in a Senegalese Population.

Soumboundou SM, Ndiaye ML, Ndiaye R et al. · 2026 · Cureus

Introduction The advent of 3D imaging has created a significant opportunity to enhance the accuracy of age estimation. By utilizing 3D segmentation, it is now possible to evaluate the three-dimensional pulp volume as an indicator of age.…

View details →DOI: 10.7759/cureus.109325
Negative / Null Result ReportMedicine

Reliability of Patellar Height Measurement in Children and Adolescents on MRI.

Jiang C, Cheng P, Liu Y et al. · 2025 · Journal of pediatric orthopedics

Introduction Imaging-based measurement indices of patellar height are essential for diagnosing patella alta in children and adolescents. The Patellotrochlear Index (PTI) measures the cartilaginous anatomy which is crucial for identifying…

View details →DOI: 10.1097/bpo.0000000000003057
Negative / Null Result ReportMedicine

Assessment of active fibrotic remodeling in patients with idiopathic pulmonary fibrosis (IPF)/progressive pulmonary fibrosis (PPF) using dual-time-point [<sup>68</sup>Ga]Ga-FAPI-46-PET/CT.

Grunert M, Horn V, Baudrexl JC et al. · 2026 · European journal of radiology

Background Progressive fibrosing interstitial lung diseases (ILD) continue to have a poor prognosis. To date, there is no imaging method that can reliably detect fibrotic remodeling processes or distinguish between active and dormant…

View details →DOI: 10.1016/j.ejrad.2026.113036
Negative / Null Result ReportMedicine

Comparison of neuromelanin-sensitive magnetic resonance imaging using different magnetic resonance protocols on the same patients with Parkinson's disease.

Hirose R, Matsuura K, Ii Y et al. · 2026 · Journal of neural transmission (Vienna, Austria : 1996)

In Parkinson's disease (PD), neuronal loss occurs in the substantia nigra (SN) and locus coeruleus (LC). Previous studies using neuromelanin-sensitive magnetic resonance imaging (NMI) at 3T MRI have described the measurement methods and…

View details →DOI: 10.1007/s00702-026-03179-z
Negative / Null Result ReportMedicine

Real-Time Perfusion Assessment with Hyperspectral Imaging After Revascularization in Peripheral Artery Disease.

Kluckner M, Hitzl W, Enzmann FK et al. · 2026 · Journal of clinical medicine

Background/Objectives : Hyperspectral imaging (HSI) facilitates noninvasive assessment of tissue perfusion in patients with peripheral arterial disease. However, available studies are either based on small cohorts and provide no comparison…

View details →DOI: 10.3390/jcm15041667
Negative / Null Result ReportMedicine

An Occupation-Focused Intervention to Promote Functioning Among Adults Aging With Diabetes and Heart Disease.

Mirza M, Fischer H, Arias D · 2026 · OTJR : occupation, participation and health

Background Aging adults with chronic diseases are at risk of functional decline. Objectives This pilot randomized control trial examined the feasibility, acceptability, and preliminary efficacy of an occupational therapy intervention to…

View details →DOI: 10.1177/15394492261446563
Negative / Null Result ReportMedicine

The Influence of Os Acromiale on Patient Outcomes After Reverse Total Shoulder Arthroplasty: A Matched Cohort Study.

Schneider BS, Pfaehler CD, Hao KA et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons

Background Although os acromiale is often noted on preoperative imaging in patients undergoing reverse total shoulder arthroplasty (rTSA), its clinical significance is ill-defined. The purpose of this study was to compare the clinical…

View details →DOI: 10.5435/jaaos-d-25-00614