A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
35 results in Replication Failure for "randomized controlled trial" · page 2 of 2
Ramasubbu D, Lewney J · 2025 · Evidence-based dentistry
Design The Brushing RemInder 4 Good oral HealTh (BRIGHT) multi-centre randomized controlled trial was based in state-funded secondary schools in England, Wales and Scotland. It had two arms, aiming to assess the clinical and cost…
Wang L, Wang X, Zhang R et al. · 2025 · The American journal of clinical nutrition
Background Gestational diabetes mellitus (GDM) affects millions of females and their children. Effective dietary strategies for early prevention are controversial. Objectives This study aims to investigate whether an individualized…
Wongkraisri C, Chusuwanrak K, Laocharoenkeat A et al. · 2025 · BMC cancer
Background Hand-foot syndrome (HFS) is a common adverse event of capecitabine causing treatment modifications. Topical urea cream can reduce sorafenib-induced hand-foot skin reaction. However, its benefit in preventing…
Lee CT, Tran D, Tsukiboshi Y et al. · 2023 · Journal of clinical periodontology
Aim This randomized controlled trial aimed to investigate the efficacy of soft-tissue augmentation (STA) with a subepithelial connective tissue graft (SCTG) or an acellular dermal matrix (ADM) on reducing tissue alterations at an immediate…
Vander Zwalmen Y, Vrijsen JN, Meuleman B et al. · 2026 · Internet interventions
Background Late-life depression (LLD) is a prevalent and debilitating condition associated with a poor long-term prognosis and high rates of chronicity. Cognitive control impairments are common in LLD and contribute to symptom persistence,…