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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

84 results for "deep learning" · page 2 of 3

Negative / Null Result ReportOpen accessEngineering

A Hybrid YOLO and Segment Anything Model Pipeline for Multi-Damage Segmentation in UAV Inspection Imagery

Rafael Cabral, Ricardo Santos, José A.F.O. Correia et al. · 2025 · Sensors

The automated inspection of civil infrastructure with Unmanned Aerial Vehicles (UAVs) is hampered by the challenge of accurately segmenting multi-damage in high-resolution imagery. While foundational models like the Segment Anything Model (SAM) offer data-efficient segmentation, their effectiveness is constrained by prompting strategies, especially for geometrically complex defects. This paper presents a comprehensive comparative analysis of deep learning strategies to identify an optimal deep learning pipeline for segmenting cracks, efflorescences, and exposed rebars. It systematically evalua

View details →DOI: 10.3390/s25216568Cited by 9
Negative / Null Result ReportOpen accessMedicine

Lessons learned from RadiologyNET foundation models for transfer learning in medical radiology

Mateja Napravnik, Franko Hržić, Martin Urschler et al. · 2025 · Scientific Reports

Deep learning models require large amounts of annotated data, which are hard to obtain in the medical field, as the annotation process is laborious and depends on expert knowledge. This data scarcity hinders a model's ability to generalise…

View details →DOI: 10.1038/s41598-025-05009-wCited by 9
Negative / Null Result ReportOpen accessEngineering

Integrating Computer Vision and GIS for Large-Scale Morphological Mapping and Driving Force Analysis of Vernacular Courtyard Dwellings

Lihua Liang, Xiaodong Li, Shutong Liu et al. · 2026 · Buildings

This study develops and applies an integrated methodology that combines deep learning-based computer vision and spatial statistics to automate the large-scale identification and analysis of morphological features in vernacular courtyard dwellings. Focusing on Liangshuaixiu dwellings in Wu’an, southern Hebei, we trained an HRNetV2 semantic segmentation model on high-resolution satellite imagery to identify and extract contours for 134,280 courtyard spaces. Core morphological parameters (area, orientation) were calculated and analyzed using GIS spatial statistics and the geographic detector mode

View details →DOI: 10.3390/buildings16061118Cited by 9
Negative / Null Result ReportOpen accessComputer Science

Confounding factors and biases abound when predicting molecular biomarkers from histological images

Muhammad Dawood, Kim Branson, Sabine Tejpar et al. · 2026 · Nature Biomedical Engineering

Deep learning models that infer clinically relevant biomarker status from tissue images are being explored as rapid and low-cost alternatives to molecular testing. Here we show, through statistical analysis across multiple cancer types, datasets and modelling approaches, that the datasets used to train these models contain strong dependencies between biomarkers and clinicopathological features, which prevent models from isolating the effect of a single biomarker and lead them to learn confounded signals. Consequently, their prediction accuracy varies substantially with the status of codependen

View details →DOI: 10.1038/s41551-026-01616-8Cited by 9
Negative / Null Result ReportOpen accessComputer Science

The added value for MRI radiomics and deep-learning for glioblastoma prognostication compared to clinical and molecular information

D. Abler, O. Pusterla, A. Joye-Kühnis et al. · 2025 · arXiv

Background: Radiomics shows promise in characterizing glioblastoma, but its added value over clinical and molecular predictors has yet to be proven. This study assessed the added value of conventional radiomics (CR) and deep learning (DL) MRI radiomics for glioblastoma prognosis ( 6 months survival) on a large multi-center dataset. Methods: After patient selection, our curated dataset gathers 1152 glioblastoma (WHO 2016) patients from five Swiss centers and one public source. It included clinical (age, gender), molecular (MGMT, IDH), and baseline MRI data (T1, T1 contrast, FLAIR, T2)

Negative / Null Result ReportMedicine

Deep Learning Reconstruction Specialized for Inner Ear: Improving Image Quality and Anatomical Structure Visualization as Compared with Conventional Hybrid-Type Iterative Reconstruction on High-Definition CT.

Nomura, Kimata, Ito et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives: To directly compare the capabilities of hybrid-type iterative reconstruction (IR) with the newly developed deep learning reconstruction (DLR) for the inner ear on high-definition CT (HDCT) obtained using the…

View details →DOI: 10.3390/diagnostics16121756
Negative / Null Result ReportMedicine

Diagnosis of Small Focal Liver Lesions (≤2 cm): A Deep Learning Approach Based on B-Mode Ultrasound and Contrast-Enhanced Ultrasound.

Xu, Wei, Zhang et al. · 2026 · Ultrasound in medicine & biology

To develop and validate a deep learning (DL) model based on feature fusion with B-mode ultrasound (BMUS) and contrast enhanced ultrasound (CEUS) images for non-invasive diagnosis of benign and malignant focal liver lesions (FLLs),…

View details →DOI: 10.1016/j.ultrasmedbio.2026.01.002
Negative / Null Result ReportMedicine

External Validation of a Deep Learning-Based Artificial Intelligence System for Ultrasound Diagnosis of Thyroid Nodules: A Two-Center Retrospective Study.

Tang, Xu, Zhao et al. · 2026 · Journal of clinical ultrasound : JCU

To investigate the performance of an artificial intelligence (AI) diagnostic system for thyroid nodule sonography based on deep learning convolutional neural network (CNN). We retrospectively included 485 thyroid nodules with definite…

View details →DOI: 10.1002/jcu.70275
Negative / Null Result ReportMedicine

MammoDenseSegNet: A Context-Aware Deep Learning Model for Dense Tissue Segmentation in Digital Mammograms.

Ganjee, Bandos, Hossain et al. · 2026 · Journal of imaging informatics in medicine

Breast density is a breast cancer risk factor. The accurate quantification of breast density requires reliable segmentation of dense tissue in mammograms, but it is a challenging task due to large variations in tissue appearance across…

View details →DOI: 10.1007/s10278-026-02029-4
Negative / Null Result ReportMedicine

Effectiveness of deep learning-based denoising on image quality and diagnostic performance of low-dose abdominal CT for acute appendicitis.

Shin, Kim, Lee · 2026 · European journal of radiology

To evaluate the effect of deep learning-based denoising on image quality and diagnostic performance of low-dose abdominal CT in diagnosing acute appendicitis, and to determine whether filtered back projection (FBP) or iterative…

View details →DOI: 10.1016/j.ejrad.2026.113037
Negative / Null Result ReportOpen accessMedicine (General)

Comparison of the Predicting Performance for Fate of Medial Meniscus Posterior Root Tear Based on Treatment Strategies: A Comparison between Logistic Regression, Gradient Boosting, and CNN Algorithms

Jae-Ik Lee, Dong-Hyun Kim, Hyun-Jin Yoo et al. · 2021 · Diagnostics

This study aimed to validate the accuracy and prediction performance of machine learning (ML), deep learning (DL), and logistic regression methods in the treatment of medial meniscus posterior root tears (MMPRT). From July 2003 to May 2018, 640 patients diagnosed with MMPRT were included. First, the affecting factors for the surgery were evaluated using statistical analysis. Second, AI technology was introduced using X-ray and MRI. Finally, the accuracy and prediction performance were compared between ML&DL and logistic regression methods. Affecting factors of the logistic regression method co

View details →DOI: 10.3390/diagnostics11071225
Negative / Null Result ReportMedicine

Is EMG Information Necessary for Deep Learning Estimation of Joint and Muscle Level States?

Schonhaut EB, Scherpereel KL, Young AJ · 2026 · IEEE transactions on bio-medical engineering

Objective Accurate, non-invasive methods for estimating joint and muscle physiological states have the potential to greatly enhance control of wearable devices during real-world ambulation. Traditional modeling approaches and current…

View details →DOI: 10.1109/tbme.2025.3577084
Negative / Null Result ReportOpen accessMedicine

Automatic monitoring of single-wall MAPSE by transesophageal echocardiography for tracking global left ventricular function irrespective of regional hypokinesia: a secondary analysis.

Yu J, Grude O, Berg EAR et al. · 2026 · Intensive care medicine experimental

Background Measuring mitral annular plane systolic excursion (MAPSE) serially in a single wall may be an effective method for monitoring global left ventricular (LV) function, especially when automated with a novel deep learning method…

View details →DOI: 10.1186/s40635-026-00898-1
Failed Experiment ReportOpen accessMedicine

Severe deviation in protein fold prediction by advanced AI: a case study.

López-Sagaseta J, Urdiciain A · 2025 · Scientific reports

Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino…

View details →DOI: 10.1038/s41598-025-89516-w
Negative / Null Result Report

Explainable Deep Learning for Lesion-Level Detection of Diabetic Retinopathy: A Segmentation Approach Using Fundus Images Graded as Mild-to-Moderate Nonproliferative Diabetic Retinopathy

Sato T, Nishitsuka K, Itoh T et al. · 2025 · Preprint

Deep learning has shown promise in diabetic retinopathy screening using fundus images. However, many existing models operate as “black boxes,” providing limited interpretability at the lesion level. This study aimed to develop an…

View details →DOI: 10.1101/2025.10.01.25337115
Negative / Null Result ReportOpen accessMedicine

Deep Learning-Based Dental Caries Diagnosis on Panoramic Radiographies: Performance of YOLOv8 Versus Human Observers.

Biçengil K, Kurt A, Naralan ME et al. · 2026 · Diagnostics (Basel, Switzerland)

Objectives : To evaluate the diagnostic performance of a YOLOv8x-based deep learning model for detecting approximal, occlusal and buccal caries on paediatric panoramic radiographs and to compare its performance with human observers with…

View details →DOI: 10.3390/diagnostics16081150
Negative / Null Result ReportMedicine

Letter to the Editor Regarding Article "Prior to Initiation of Chemotherapy, Can We Predict Breast Tumor Response? Deep Learning Convolutional Neural Networks Approach Using a Breast MRI Tumor Dataset".

Brunekreef J · 2024 · Journal of imaging informatics in medicine

The cited article reports on a convolutional neural network trained to predict response to neoadjuvant chemotherapy from pre-treatment breast MRI scans. The proposed algorithm attains impressive performance on the test dataset with a mean…

View details →DOI: 10.1007/s10278-024-01129-3
Negative / Null Result ReportMedicine

Comparative performance of one-stage and two-stage deep learning models for instance segmentation of overhanging dental restorations on bitewing radiographs.

Hatipoğlu Ö, Başar Ö, Mağat G et al. · 2026 · Scientific reports

Accurate detection of overhanging dental restorations on bitewing radiographs is clinically important but remains challenging due to subtle marginal discrepancies. This study aimed to develop and compare deep learning-based instance…

View details →DOI: 10.1038/s41598-026-57540-z
Negative / Null Result ReportMedicine

[Deep learning-based assessment of periodontal ligament area changes in maxillary central incisors under different orthodontic regimens using cone beam CT images].

Li RQ, Su S, Zhan LP et al. · 2026 · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

Objective: To investigate the differences in the changes of periodontal ligament area (PDLA) and related clinical indicators before and after maxillary central incisor movement under different orthodontic treatment regimens. Methods: This…

View details →DOI: 10.3760/cma.j.cn112144-20250722-00280
Negative / Null Result ReportMedicine

Validation of aortic valve calcification quantification on contrast-enhanced computed tomography against ex vivo gravimetric analysis: comparison of fixed Hounsfield unit thresholds and deep learning segmentation.

Jiang D, Zhang W, Liu L et al. · 2026 · BMC cardiovascular disorders

Background Accurate quantification of aortic valve calcification (AVC) on contrast-enhanced computed tomography angiography (CTA) is pivotal for planning surgical and transcatheter aortic valve replacement. The optimal Hounsfield unit (HU)…

View details →DOI: 10.1186/s12872-026-06108-w
Negative / Null Result ReportMedicine

Design and optimization of an automatic deep learning-based cerebral reperfusion scoring (TICI) using thrombus localization.

Folcher A, Piters J, Wallach D et al. · 2025 · Journal of neuroradiology = Journal de neuroradiologie

Background The Thrombolysis in Cerebral Infarction (TICI) scale is widely used to assess angiographic outcomes of mechanical thrombectomy despite significant variability. Our objective was to create and optimize an artificial intelligence…

View details →DOI: 10.1016/j.neurad.2025.101366