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WASTE Journal
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

AllReplication FailureNegative / Null Result ReportFailed Experiment ReportAbandoned HypothesisMethods Dead-EndShort NoteNull DatasetProtocol

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

By fieldMedicine 12,367Computer Science 765Biochemistry, Genetics and Molecular Biology 476Social Sciences 324Psychology 323Physics 280Neuroscience 268Economics, Econometrics and Finance 222Environmental Science 194Mathematics 163Agricultural and Biological Sciences 160Engineering 157

515 results for "randomized controlled trial" · page 18 of 18

Negative / Null Result ReportMedicine

Evaluating the Impact of Ursodeoxycholic Acid on Hepatic Clearance of [<sup>99m</sup>Tc]Tc-Sestamibi: A Randomized Controlled Trial to Improve Myocardial Perfusion Imaging.

Hosseinzadeh E, Arefnia M, Bayat M et al. · 2026 · Cancer biotherapy & radiopharmaceuticals

Background Intense hepatobiliary uptake of [ 99m Tc]Tc-sestamibi in myocardial perfusion scintigraphy (MPS) often degrades image quality by obscuring the inferior myocardial wall, leading to equivocal studies. While nonpharmacological…

View details →DOI: 10.1177/10849785251376736
Negative / Null Result ReportMedicine

Lactobacillus rhamnosus GG to Reduce Necrotising Enterocolitis, Sepsis, and Mortality in Very Low Birth Weight Infants: A Randomized Controlled Trial.

Shah S, Kaul A, Pandey P et al. · 2026 · Indian pediatrics

Objectives To evaluate the efficacy of oral Lactobacillus rhamnosus GG (LGG) in reducing neonatal enterocolitis (NEC), sepsis and mortality in very low birth weight (VLBW) infants. Methods This open-label randomized controlled trial…

View details →DOI: 10.1007/s13312-025-00252-w
Negative / Null Result ReportMedicine

Computer-aided polyp detection multicenter international randomized controlled study with a focus on community clinics: Geriatric Assessment-Driven Intervention clinical trial.

Leggett CL, Plowman RS, Surace L et al. · 2026 · Gastrointestinal endoscopy

Background and aims Computer-aided polyp detection (CADe) systems can enhance polyp detection, although their performance has largely been evaluated at academic rather than community practices. This randomized controlled trial evaluated…

View details →DOI: 10.1016/j.gie.2025.12.290
Negative / Null Result ReportMedicine

Effect of vaginal estrogen supplementation for luteal phase support in the GnRH antagonist protocol on pregnancy outcomes for IVF/ICSI cycles: a randomized controlled trial.

Yang X, Zhu L, Chen R et al. · 2026 · Human reproduction open

Study question Does adding vaginal estradiol to standard progesterone luteal phase support improve ongoing pregnancy rates in normal-responder IVF/ICSI patients undergoing GnRH antagonist cycles? Summary answer The addition of vaginal…

View details →DOI: 10.1093/hropen/hoag042
Negative / Null Result ReportMedicine

Energy restriction and iron supplementation improve iron status in women with obesity regardless of red meat consumption: a randomized controlled trial.

Ortiz-Gutiérrez S, Serralde-Zúñiga AE, González-Salazar LE et al. · 2026 · Scientific reports

Iron deficiency without anemia (IDNA) may be linked to obesity-related inflammation. Weight reduction and heme-iron intake from red meat are proposed to improve iron status. This randomized controlled trial (NCT06104800) assessed the…

View details →DOI: 10.1038/s41598-026-53056-8