Negative / Null Result ReportOpen accessMedicine
Gieira S Jones, Heather Spencer Feigelson, Roni T Falk et al. · 2019 · PLoS ONE
Background Breast density, as estimated by mammography, is a strong risk factor for breast cancer in pre- and postmenopausal women, but the determinants of breast density have not yet been established. The aim of this study was to assess if urinary estrogens or gut microbiota alterations are associated with mammographic density in postmenopausal women. Methods Among 54 cancer-free, postmenopausal controls in the Breast and Colon Health study, we classified low- versus high-density women with Breast Imaging Reporting and Data System (BI-RADS, 5th edition) mammographic screening data, then asses
View details →DOI: 10.1371/journal.pone.0216114 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Aves Editorial Aves Editorial · 2019 · Urology Research and Practice
Abstract Introduction: Lower urinary tract symptoms (LUTS) associated with BPH and erectile dysfunction (ED) are common problems in aging male. In this study, we aimed to determine the causes of the relationship between LUTS and ED, and the possible effects of body mass index (BMI), serum leptin, free testosterone (fT) and lipid levels on LUTS and ED etiology. Materials and Methods: Between June 2003 and February 2004, 46 patients were recruited in this study. All patients underwent physical examination including digital rectal examination, urine analysis, uroflowmetry and residual urine volum
Negative / Null Result ReportOpen accessDentistry
Kavita Hotwani, Krishna Sharma, Arpan Jaiswal · Dental Press Journal of Orthodontics
ABSTRACT Objective: The present study was an attempt to investigate tongue/mandible volume ratio in children, using volumetric magnetic resonance imaging (MRI) for early screening and to aid in treatment planning. Methods: Volumetric evaluation of tongue volume/mandible volume ratio (TV/MV ratio) in children with obstructive sleep apnea (OSA) using MRI was carried out retrospectively on available DICOM MR images of children in the age group of 10-14 years. MRI image records of patients diagnosed with OSA were obtained from interventional radiology department records, at Sharad Pawar Dental Col
View details →DOI: 10.1590/2177-6709.23.4.072-078.oar Negative / Null Result ReportOpen accessVeterinary medicine
Evangelia Maniaki, Carmen Pineda, Angie Hibbert et al. · 2024 · Frontiers in Veterinary Science
ObjectivesThis case-control study aimed to evaluate calcitonin response in naturally occurring hypercalcemia in cats and assess the relationships between calcitonin and ionized calcium (iCa) and examine relationships between calcitonin, iCa and bone turnover.MethodsHypercalcemic cats (persistently increased iCa concentration [>1.40 mmol/l]) were identified retrospectively via a medical database search; additional hypercalcemic and normocalcemic cats were recruited prospectively. Data regarding routine biochemical and urine testing, diagnostic imaging and additional blood testing were obtained.
View details →DOI: 10.3389/fvets.2024.1399942 Negative / Null Result ReportMedicine
J. Hannestad, Tiffanie Duclos, Whitney Chao et al. · 2021 · Journal of Alzheimer's Disease
Background: The plasma fraction GRF6019 shows multiple benefits on brain aging in mice, including enhanced cognition, neurogenesis, and synaptic density, as well as reduced neuroinflammation. Objective: To evaluate the safety,…
View details →DOI: 10.3233/jad-210011 Negative / Null Result Report
Kienka, Kienka, · 2026 · Journal of Professional Counselling
One of the rapidly growing global concerns today is the abuse of various substances that are linked with mental health with significant threat to the psychosocial challenges common in Nigeria. One of the pertinent problems is the…
View details →DOI: 10.61955/iopjof Negative / Null Result ReportOpen accessMedicine
S. T. C. Ariwicaksono, R. B. Prasetyo, Nindra Prasadja et al. · 2019 · International Journal of Applied Pharmaceutics
Objective: Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate associated with aging. BPH can cause lower urinary tract syndrome (LUTS). Medical therapy for patients with moderate and severe LUTS symptoms…
View details →DOI: 10.22159/ijap.2019.v11s6.33558 Negative / Null Result ReportMedicine
M. Hahnemann, B. Karger, S. Banaschak et al. · 2026 · Pediatric Radiology
Background In pediatric abusive head trauma (AHT), retinal hemorrhages are a key diagnostic feature. Detection by fundoscopy may be delayed or limited, whereas magnetic resonance imaging (MRI) enables non-invasive, objective assessment on…
View details →DOI: 10.1007/s00247-026-06558-6 Negative / Null Result ReportMedicine
Li B · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
Background Preoperative imaging factors associated with absorbable plate reconstruction outcomes for medial orbital wall fractures are not well-established. The role of muscle cone integrity on computed tomography (CT) has not been…
View details →DOI: 10.1016/j.joms.2026.04.022 Negative / Null Result ReportOpen accessMedicine
Pomozi E, Zatyko DZ, Suhai FI et al. · 2026 · Journal of clinical medicine
Background : Lower limb arterial calcification (LLAC) is a robust imaging biomarker of peripheral artery disease (PAD) severity. Vitamin K antagonists are presumed to accelerate cardiovascular calcification. Direct oral anticoagulants…
View details →DOI: 10.3390/jcm15093399 Negative / Null Result ReportOpen accessMedicine
Vidal A, Teles AM, Cardoso M et al. · 2026 · Dentistry journal
Cone-beam computed tomography (CBCT) is widely utilized in endodontics for evaluating root canal shaping outcomes, offering critical three-dimensional imaging capabilities. This study aims to assess the differences in apical and root canal…
View details →DOI: 10.3390/dj14020114 Negative / Null Result ReportMedicine
Shen M, Li H, Liu H et al. · 2026 · Orthopaedic surgery
Background To explore the influence of the new stage and classification system based on the correlation between MRI and pathological features on the collapse, symptoms, and function of femoral head necrosis. Existing radiographic staging…
View details →DOI: 10.1111/os.70351 Negative / Null Result ReportOpen accessMedicine
Liu J, Wu Y, Yang D et al. · 2026 · BMC medical imaging
BACKGROUND: Glomerulonephritis (GN) is a major contributor to chronic kidney disease, highlighting the need for reliable biomarker to monitor GN. This study aimed to evaluate the potential of diffusion kurtosis imaging (DKI) for dynamic…
View details →DOI: 10.1186/s12880-026-02197-3 Negative / Null Result ReportMedicine
Dantagnan CA, Salem C, Charavet C et al. · 2026 · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Introduction This study aimed to compare the effect of artificial saliva (AS) aging on the trueness and precision of direct-printed aligners vs thermoformed aligners. Methods Four types of aligners were manufactured from the same reference…
View details →DOI: 10.1016/j.ajodo.2025.11.021 Negative / Null Result ReportOpen accessMedicine
Hung E, Negraeff A, Watson C et al. · 2026 · Journal of medical entomology
Blood-feeding stable flies, Stomoxys calcitrans (L.), are reportedly attracted to conspecific feces. We investigated whether stable flies are attracted to fly feces-derived bacteria, and whether attraction varies with bacterial species and…
View details →DOI: 10.1093/jme/tjag084 Negative / Null Result ReportOpen accessEngineering
Kushal Mehta, Arshita Jain, Jayalakshmi Mangalagiri et al. · 2020 · arXiv
We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as a Random Forest in order to combine CT imagery with biomarker annotation and volumetric radiomic features. We analyze and compare the performance of the algorithm using only imagery, only biomarkers, combined imagery + biomarkers, combined imagery + volumetric radiomic features and finally the combination of imagery + biomarkers + volumetric features in orde
Negative / Null Result ReportOpen accessComputer Science
Charles Jin, Melinda Sun, Martin Rinard · 2021 · arXiv
We propose a novel clustering mechanism based on an incompatibility property between subsets of data that emerges during model training. This mechanism partitions the dataset into subsets that generalize only to themselves, i.e., training on one subset does not improve performance on the other subsets. Leveraging the interaction between the dataset and the training process, our clustering mechanism partitions datasets into clusters that are defined by--and therefore meaningful to--the objective of the training process. We apply our clustering mechanism to defend against data poisoning attacks,
Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Xiaotong Xu, Jinglan Jin, Yuwei Liu et al. · 2023 · BMC Gastroenterology
Abstract Background and aims To investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and thromboelastography (TEG) to serve as a predictor of portal vein thrombosis (PVT) in patients with liver cirrhosis. Additionally, we examined the clinical significance of the above indicators in terms of disease progression. Methods A total of 123 patients with liver cirrhosis were recruited from May 2021 to December 2021, according to the imaging findings. They were divided into the PVT group (n = 52) and the non-PVT group (n = 71). Furthermore, patients
View details →DOI: 10.1186/s12876-022-02632-z Negative / Null Result ReportOpen accessMedicine
Elif Özdemir, Şeyda Türkölmez · 2020 · Ankara Medical Journal
INTRODUCTION: This study aims to disclose the frequency and clinical significance of incidental prostatic uptake during FDG PET imaging. METHODS: FDG PET images of 1839 male patients undergoing imaging for non-prostate and non-urinary bladder malignancy indications were retrospectively reviewed for the presence of incidental prostatic FDG uptake. Prostatic volume, calcification and the presence and pattern of FDG uptake were evaluated. Further follow-up prostatic evaluation results were comparatively assessed. RESULTS: Incidental prostatic FDG uptake was detected in 41 out of 1839 patients(2.2
View details →DOI: 10.5505/amj.2020.93653 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Eric V. Li, Sai K. Kumar, Jonathan A. Aguiar et al. · 2024 · BJUI Compass
Abstract Objective This study aimed to evaluate the association of dynamic contrast enhancement (DCE) with clinically significant prostate cancer (csPCa, Gleason Grade Group ≥2) and compare biparametric magnetic resonance imaging (bpMRI) and multiparametric MRI (mpMRI) nomograms. Subjects/patients and methods We identified a retrospective cohort of biopsy naïve patients who underwent pre‐biopsy MRI separated by individual MRI series from 2018 to 2022. csPCa detection rates were calculated for patients with peripheral zone (PZ) lesions scored 3–5 on diffusion weighted imaging (DWI) with availab
View details →DOI: 10.1002/bco2.415 Negative / Null Result ReportOpen accessMedicine
Philipp Fuelkell, Soenke Langner, Nele Friedrich et al. · 2018 · PLoS ONE
OBJECTIVES:To investigate acoustic noise reduction, image quality and white matter lesion detection rates of cranial magnetic resonance imaging (MRI) scans acquired with and without sequence-based acoustic noise reduction software. MATERIAL AND METHODS:Thirty-one patients, including 18 men and 13 women, with a mean age of 58.3±14.5 years underwent cranial MRI. A fluid-attenuated inversion recovery (FLAIR) sequence was acquired with and without acoustic noise reduction using the Quiet Suite (QS) software (Siemens Healthcare). During data acquisition, peak sound pressure levels were measured wit
View details →DOI: 10.1371/journal.pone.0206196 Negative / Null Result ReportOpen accessPlant culture
Simone Pietro Garofalo, Vincenzo Giannico, Beatriz Lorente et al. · 2024 · Frontiers in Plant Science
IntroductionIn the context of climate change, monitoring the spatial and temporal variability of plant physiological parameters has become increasingly important. Remote spectral imaging and GIS software have shown effectiveness in mapping field variability. Additionally, the application of machine learning techniques, essential for processing large data volumes, has seen a significant rise in agricultural applications. This research was focused on carob tree, a drought-resistant tree crop spread through the Mediterranean basin. The study aimed to develop robust models to predict the net assim
View details →DOI: 10.3389/fpls.2024.1302435 Negative / Null Result ReportOpen accessMedicine
Joan Hermosura, Everett Lohman, Brenda Bartnik-Olson et al. · 2024 · PLoS ONE
Objectives The main purpose of this research study was to compare mean modified straight-leg raise test (mSLR) and hamstring muscle length (HL) between chronic non-specific low back pain (LBP) and healthy subjects to understand the possibility of neuropathic causes in LBP population as it may impact the diagnosis and treatment of LBP. Another purpose was to compare mean mSLR between those with lumbar nerve root impingement and those without as determine by magnetic resonance imaging (MRI). Methods The design of the study is cross sectional and included 32 subjects with ages ranging from 18-50
View details →DOI: 10.1371/journal.pone.0298257 Negative / Null Result ReportOpen accessMedicine
Rudhir Jaga, Dinell Behari, Anton P Doubell et al. · 2022 · African Journal of Emergency Medicine
Introduction: Intended for use by prehospital first responders, the Lubo TM cervical collar is an adjustable, radiolucent, single-use device that incorporates a mechanical jaw thrust mechanism. The combination enables non-invasive airway management in cases of trauma where cervical motion restriction is necessary. The potential benefits include use as an airway adjuvant maintaining upper airway patency, reducing provider task loading. The limited research on the device efficacy and safety requires further investigation.Methods: A randomized, crossover, interventional study was performed to com
View details →DOI: 10.1016/j.afjem.2022.07.008 Negative / Null Result ReportOpen accessBiology (General)
Kevin Hoffseth, Emily Busse, Josue Jaramillo et al. · 2021 · Frontiers in Cell and Developmental Biology
Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones, and tendons, all of which regenerate after digit tip amputation, making it a powerful model for multi-tissue regeneration. Bone integrity relies upon a balanced remodeling between bone resorption and formation, which, when disrupted, results in changes to bone architecture and biomechanics, particularly during aging. In this study, we used recently developed techniques to evalu
View details →DOI: 10.3389/fcell.2021.749055 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Naoki Akizue, Tomoaki Matsumura, Daisuke Maruoka et al. · 2018 · Endoscopy International Open
Background and study aims Endoscopic submucosal dissection (ESD) requires advanced skills to perform safely without complications. The current study evaluated the usefulness of a novel three-dimensional (3D) imaging system in ESD using porcine stomachs. Methods Four endoscopists (two trainees and two experts) performed eight ESD procedures using both 3D and 2D images. The usefulness of 3D image versus 2D image was evaluated by visibility and procedure time. In addition, occurrence of eyestrain and dizziness in 3D image was assessed. Results En bloc resection was successfully achieved, without
View details →DOI: 10.1055/a-0761-9649 Negative / Null Result ReportOpen access
Igwe, Nwobueze olru · 2023
This paper tried to examine correlation with different imaging techniques and aortic stenosis severity. There was no significant correlation found between the diastolic AVA area and AR, although a positive tendency was observed between the…
Negative / Null Result ReportOpen access
Wood, Joanne M. · 2002
It has been suggested that over 90% of the sensory information for driving is visual. Despite this belief, traditional studies have failed to demonstrate that increased crash rates arise from impaired vision. However, more recent studies…
Negative / Null Result ReportOpen access
Wanying Xie, Christopher Cheng, Anthony Goh Whatt et al. · 2014
We present a case of a 63-year-old gentleman, who had an initial negative prostate needle biopsy, but persistently elevated prostate-specific antigen levels. An magnetic resonance imaging study of the prostate failed to demonstrate the…
View details →DOI: 10.4103/1450-1147.144824 Negative / Null Result ReportOpen access
I. G. Rusakov, R. V. Ulianov, E. V. Filonenko et al. · 2015
The main challenge of treating non-muscle invasive bladder cancer is multifocal tumors. Current methods of diagnosis are failed to detect all superficial flat tumor lesions in bladder mucosa. The use of fluorescence imaging with…
View details →DOI: 10.24931/2413-9432-2015-4-3-29-35 