Negative / Null Result ReportOpen accessMedicine
Grynkiewicz M, Buffi NM, Fasulo V et al. · 2025 · Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques
Introduction Research results suggest that high-resolution ultrasonography (microUS) can be used to estimate the risk of prostate cancer (PCa) and identify suspicious areas, enabling precise biopsy during examination. Aim The aim of the…
View details →DOI: 10.20452/wiitm.2025.17978 Negative / Null Result ReportOpen accessMedicine
Kim DH, Chun MK, Lim SY et al. · 2026 · Pediatric emergency care
Objectives This retrospective observational study evaluated the diagnostic efficiency of routine magnetic resonance imaging (MRI) in pediatric patients with facial palsy (FP) in the emergency department (ED). Methods Pediatric patients…
View details →DOI: 10.1097/pec.0000000000003506 Negative / Null Result ReportOpen accessMedicine
Tunçez HÇ · 2026 · Polish journal of radiology
Purpose To evaluate the Kaiser score (KS) on magnetic resonance imaging (MRI) in patients diagnosed with breast cancer and to identify clinical, pathological, and radiological factors associated with false-negative Kaiser score. Material…
View details →DOI: 10.5114/pjr/217365 Negative / Null Result ReportOpen accessMedicine
Jones GT, Bennett AN, Sengupta R et al. · 2025 · Arthritis care & research
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop…
View details →DOI: 10.1002/acr.25581 Negative / Null Result Report
Mayorga AP, Peña CO, Muñoz DB et al. · 2026 · Preprint
Abstract Background The rapid urease test (RUT) is widely used for Helicobacter pylori (H. pylori) diagnosis, but its diagnostic performance in advanced gastric atrophy remains poorly characterized. Aims To evaluate RUT accuracy against…
View details →DOI: 10.21203/rs.3.rs-9490483/v1 Negative / Null Result Report
Wright L, Hamze J, Nagrani TR et al. · 2026 · Preprint
Abstract Background Coronary artery disease (CAD) places a disproportionate burden on rural Appalachian communities. Scioto County, Ohio has among the highest rates of CAD-related hospitalizations in the state, approaching double the…
View details →DOI: 10.21203/rs.3.rs-9246863/v1 Negative / Null Result ReportMedicine
Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →DOI: 10.1016/j.surg.2026.110136 Negative / Null Result ReportOpen accessMedicine
Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →DOI: 10.5114/kitp.2026.160677 Failed Experiment Report
Alkathiri O, Liberman M · 2026 · Preprint
Mediastinal staging remains a critical step in the management of non-small-cell lung cancer (NSCLC), as it directly impacts treatment planning, surgical decision-making, and overall prognosis. For many years, mediastinoscopy was considered…
View details →DOI: 10.20944/preprints202604.0470.v1 Negative / Null Result Report
Alger JR, Gupta I, Farkouh L et al. · 2026 · Preprint
Background Prior neuroimaging suggests brain differences between children with attention deficit hyperactivity disorder due to prenatal alcohol exposure (ADHD+PAE) and non-exposed children with ADHD due to other, e.g., familial, causes…
View details →DOI: 10.64898/2026.05.25.26354065 Negative / Null Result Report
TEZCE A, DURMUŞ E · 2026 · Preprint
Abstract Purpose The objective of this study is to compare the diagnostic efficacy of Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) in detecting lumbar spondylolysis among patients presenting with chronic low back pain, and…
View details →DOI: 10.21203/rs.3.rs-9247900/v1 Negative / Null Result ReportOpen accessMedicine
Lükewille L, Wiegand S, Fazel A et al. · 2026 · Journal of cancer research and clinical oncology
Purpose Sentinel lymph node biopsy (SLNB) is a standard procedure for nodal staging in cutaneous melanoma. However, its diagnostic performance in the head and neck region remains limited due to complex lymphatic drainage patterns. This…
View details →DOI: 10.1007/s00432-026-06499-5 Negative / Null Result ReportMedicine
Greenfield PT, Phillips BB, Throckmorton TW et al. · 2026 · Journal of surgical orthopaedic advances
Despite studies highlighting magnetic resonance imaging (MRI)/magnetic resonance angiogram (MRA) accuracy in diagnosing shoulder pathologies, there remains a paucity of data regarding false negative results of these tests. The authors…
Negative / Null Result Report
AL-Saeedi A, Abdulamir AS, Aufi IM et al. · 2025 · Preprint
Abstract Background The widespread use of accurate real-time RT-PCR tests for community individuals is a critical approach to managing the disease and reducing COVID-19 transmission effectively. In addition, serological ELISA assays are…
View details →DOI: 10.21203/rs.3.rs-8233598/v1 Negative / Null Result ReportMedicine
Ceacero-Marín D, Puig-Pey Comas I, Nieto-Moragas J et al. · 2026 · Scandinavian journal of clinical and laboratory investigation
Background The direct antiglobulin test (DAT) is a key diagnostic tool in evaluating autoimmune haemolytic anaemia. However, indiscriminately ordering this test, together with certain methodological limitations, can compromise the…
View details →DOI: 10.1080/00365513.2025.2605640 Methods Dead-EndMedicine
Candiago Júnior AF, Traebert J, Cordeiro EZ · 2025 · Revista do Colegio Brasileiro de Cirurgioes
Introduction Sentinel lymph node biopsy is fundamental for staging and prognostication of cutaneous melanoma when indicated. However, it still yields a high rate of negative results. To reduce the rate of true negatives, oncology centers…
View details →DOI: 10.1590/0100-6991e-20253873-en Methods Dead-EndMedicine
de Andrade Filho PH, da Silva Souza Barbosa R, Tafner GP et al. · 2026 · Journal of clinical anesthesia
Background The pericapsular nerve group (PENG) block has emerged as an effective regional anesthesia technique for managing hip pain, offering substantial analgesia while preserving motor function. However, the minimum effective volume…
View details →DOI: 10.1016/j.jclinane.2026.112267 Methods Dead-EndMedicine
Hirsch W, Enns EA, Khoruts A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Fecal microbiota transplantation (FMT) is the cost-effective strategy for managing recurrent Clostridioides difficile infection (rCDI). Prior costing models assumed FMT administration via colonoscopy. With the commercialization…
View details →DOI: 10.1093/cid/ciag263 Negative / Null Result ReportMedicine
Leung A, Koo J · 2026 · CNS drugs
Dermatological delusional disorders, such as delusional infestation (DI), are a unique type of psychosis in which the patient experiences specific delusions, such as parasites or inorganic materials that come out of their skin. Originally,…
View details →DOI: 10.1007/s40263-026-01309-5 Negative / Null Result ReportMedicine
Chu BK, Abdelbaki A, Nikahd M et al. · 2026 · Journal of clinical gastroenterology
Background The optimal timing for endoscopic retrograde cholangiopancreatography (ERCP) in managing uncomplicated acute biliary pancreatitis (ABP) remains unclear. This population-based study assessed the impact of ERCP timing on outcomes…
View details →DOI: 10.1097/mcg.0000000000002341 Negative / Null Result Report
Juhasz J, DeFeis B, Britton MK et al. · 2026 · Preprint
ABSTRACT Introduction Brain-predicted age, estimated from structural MRI data, is a machine learning biomarker of biological brain aging. Greater brain age gap (BAG) indicates advanced brain aging and is associated with cognitive decline…
View details →DOI: 10.64898/2026.06.04.26354935 Negative / Null Result ReportMedicine
Larkio J, Söderström M, Holmström J et al. · 2026 · European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Objective The aim of this retrospective observational study was to analyse imaging and patient related parameters of splenic artery aneurysms (SAAs) and their impact on SAA growth and rupture. Methods The term "aneurysm" was systematically…
View details →DOI: 10.1016/j.ejvs.2026.06.019 Negative / Null Result ReportMedicine
Micheli K, Koutra K, Markakis G · 2026 · International journal of aging & human development
This study examines whether aging anxiety (based on terror management theory) or demographic and experiential factors better explain attitudes toward older adults among social work students and professionals. Cross-sectional data were…
View details →DOI: 10.1177/00914150261456748 Negative / Null Result Report
Yin M, Nguyen VK, Nathan A et al. · 2026 · Preprint
Background It is well-established that males have a higher mortality risk than females. Immune cells and their function are known to undergo characteristic changes during aging, and immune cells are known to have sex differences. Immune…
View details →DOI: 10.64898/2026.05.27.26354256 Negative / Null Result Report
Giblett MJ, Lind P, Medland S · 2026 · Preprint
Purpose: Individuals with Autism and/or ADHD often experience stigma related to their diagnosis. Social camouflaging is a coping strategy they can use to hide neurodivergent traits and difficulties, possibly as a response to stigma.…
View details →DOI: 10.31234/osf.io/u2p54_v2 Negative / Null Result ReportMedicine
Smith A, Dixit I, Zhang L et al. · 2026 · JAMA dermatology
Importance Cardiovascular disease (CVD) is the leading cause of mortality in patients with psoriasis, yet structured CVD prevention is not routinely embedded in dermatology care. Objective To evaluate the effectiveness of a text-messaging…
View details →DOI: 10.1001/jamadermatol.2026.1070 Negative / Null Result ReportOpen accessMedicine
Zawar I, Zhu S, Quigg M et al. · 2026 · Brain communications
Epilepsy is a common comorbidity of Alzheimer's disease (AD) and related dementias (ADRD). Both epilepsy and ADRD affect the mesial temporal structures in volume and morphology. Nonetheless, mesial temporal shape and volume asymmetry…
View details →DOI: 10.1093/braincomms/fcag179 Negative / Null Result ReportMedicine
Jin X, Shen T, Wang Y et al. · 2026 · JBI evidence implementation
Introduction Auditory hallucinations, persistent and distressing symptoms in patients with schizophrenia, are often poorly controlled by antipsychotics. Structured non-pharmacological interventions remain limited in routine clinical…
View details →DOI: 10.1097/xeb.0000000000000595 Negative / Null Result ReportMedicine
Maisch P, Hamidi Madani M, Koziarz A et al. · 2026 · The Cochrane database of systematic reviews
Rationale Disease recurrence and progression remain major challenges in the treatment of non-muscle invasive bladder cancer (NMIBC). Blue light-enhanced transurethral resection of bladder cancer (TURBT) is an approach to improve staging…
View details →DOI: 10.1002/14651858.cd013776.pub3 Negative / Null Result Report
Chusyd DE, Austad SN, Brown JL et al. · 2026 · Preprint
Early-life trauma in humans, including maternal loss, is strongly associated with increased risk of chronic diseases, reduced life expectancy, and accelerated biological aging, as measured through epigenetic modifications, such as DNA…
View details →DOI: 10.64898/2026.04.03.716431 