Negative / Null Result ReportOpen accessEngineering
Arjun D. Desai, Francesco Caliva, Claudia Iriondo et al. · 2020 · arXiv
Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D knee MRI from 88 subjects at two timepoints with ground-truth articular (femoral, tibial, patellar) cartilage and meniscus segmentations was standardized. Challenge submissions and a majority-vote ensemble were evaluated using Dice score, average symmetric surface distance, volumetric overlap error, and coefficient of variation on a hold-out test set. Simil
Negative / Null Result ReportOpen accessMedicine
Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
View details →DOI: 10.4258/hir.2026.32.1.14 Negative / Null Result ReportMedicine
Sabri H, Baniameri S, Kataria P et al. · 2026 · Journal of periodontology
Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α-Klotho, an anti-aging protein with anti-inflammatory properties, has been associated with…
View details →DOI: 10.1002/jper.70080 Failed Experiment ReportMedicine
Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging
Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…
View details →DOI: 10.1016/j.clinimag.2025.110680 Negative / Null Result ReportOpen accessMedicine
Bayar E, Cengiz T, Erdoğan F et al. · 2026 · BMC geriatrics
BACKGROUND: Hip fractures represent a major public health concern due to their increasing incidence in the aging population and their association with significant morbidity and mortality. Comorbidities are known to complicate both the…
View details →DOI: 10.1186/s12877-026-07441-7 Negative / Null Result ReportMedicine
Karlin NJ · 2026 · Psychological reports
Given the unique challenges faced by frontier aging older adults, such as limited access to healthcare and social services, the potential for different functional disabilities as compared to rural older adults exists. By comparing frontier…
View details →DOI: 10.1177/00332941261455769 Negative / Null Result ReportMedicine
Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…
View details →DOI: 10.3390/medicina62061034 Negative / Null Result Report
Armi S, Abharian PH, Barzkar F et al. · 2026 · Preprint
Abstract Introduction: Mild cognitive impairment (MCI), often misattributed to normal aging, commonly precedes dementia, highlighting the critical need for early identification to enable timely intervention and management. Objective: This…
View details →DOI: 10.21203/rs.3.rs-9918242/v1 Negative / Null Result ReportOpen accessComputer Science
Jan Tiemann, Matthew McGinity, Ulrik Günther · 2026 · arXiv
In contemporary biology and medicine, 3D microscopy is one of the most widely-used techniques for imaging and manipulation of various kinds of samples. Navigating such a micrometer-sized, 3-dimensional sample under the microscope -- e.g. to find relevant imaging regions -- can pose a tedious challenge for the experimenter. In this paper, we examine whether 2D desktop, 3D desktop, or Virtual Reality (VR) interfaces provide the best user experience and performance for the exploration of 3D samples. We invited 12 skilled microscope operators to perform two different exploration tasks in 2D, 3D an
Negative / Null Result Report
Chen J, Li X, Tian Z et al. · 2026 · Preprint
Abstract Objective To investigate the structural basis of white matter fiber tracts in cognitive dysfunction following radiochemotherapy in patients with frontal lobe glioma. Methods A total of 40 patients with frontal lobe glioma who…
View details →DOI: 10.21203/rs.3.rs-9225199/v1 Negative / Null Result ReportOpen accessMedicine
Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine
Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…
View details →DOI: 10.1186/s12890-026-04326-8 Negative / Null Result ReportMedicine
Kużdżał A, Gambuś K, Moszczyński K et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Positron emission tomography (PET) using 18-fluorodeoxyglucose (18-FDG) is the primary imaging modality for mediastinal staging of lung cancer. Higher standardized uptake value (SUVmax) reportedly correlates with more aggressive…
View details →DOI: 10.17219/acem/210368 Negative / Null Result Report
Jose A. Rivera, Carmen E. Gonzalez, Tonita Bates · 2024 · JCO Oncology Practice
327 Background: Delayed assessment of diagnostic imaging (DI) significant actionable findings (AFs) at an oncological center prompted the creation of a safety net system which used technological advancements to improve communication…
View details →DOI: 10.1200/op.2024.20.10_suppl.327 Negative / Null Result Report
Ramezani A, Rahimi S, Soltani A et al. · 2026 · Preprint
Abstract Background : Chronic pain is highly prevalent among older adults and has been shown to be associated with differences in cognitive function. While pain intensity reflects the severity of pain, pain interference assesses the extent…
View details →DOI: 10.21203/rs.3.rs-8852522/v1 Negative / Null Result Report
Santos S, Palma-Moreira A, Dias I · 2025 · Preprint
This study aimed to examine the effect of public policies on talent retention in the Portuguese Public Administration and whether the participants' managerial status moderates this relationship. A total of 282 individuals, active workers…
View details →DOI: 10.20944/preprints202511.1559.v1 Negative / Null Result ReportMedicine
Smeulders N, Gaze MN, Guérin F et al. · 2026 · Journal of pediatric surgery
Background Risk stratification of rhabdomyosarcoma (RMS) requires accurate staging, with histological nodal assessment being of critical importance for specific tumour sites. This report explores the value of surgical nodal staging in…
View details →DOI: 10.1016/j.jpedsurg.2026.163162 Negative / Null Result ReportMedicine
Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health
This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…
View details →DOI: 10.1007/s10943-026-02694-3 Negative / Null Result ReportOpen accessMedicine
Laughlin M, Jack JT, Stephens SE et al. · 2026 · PloS one
Intracardiac flow analysis aims to evaluate blood flow patterns and associated parameters for the assessment of cardiac function. However, there is limited understanding as to how flow parameters are influenced by various sources, such as…
View details →DOI: 10.1371/journal.pone.0349435 Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Louis Jalouzot, Alexis Thual, Yair Lakretz et al. · 2025 · arXiv
We investigate optimal strategies for decoding perceived natural speech from fMRI data acquired from a limited number of participants. Leveraging Lebel et al. (2023)'s dataset of 8 participants, we first demonstrate the effectiveness of training deep neural networks to predict LLM-derived text representations from fMRI activity. Then, in this data regime, we observe that multi-subject training does not improve decoding accuracy compared to single-subject approach. Furthermore, training on similar or different stimuli across subjects has a negligible effect on decoding accuracy. Finally, we fin
Negative / Null Result ReportOpen accessMedicine
Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery
Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…
View details →DOI: 10.1097/moo.0000000000001102 Negative / Null Result ReportOpen accessMedicine
Hoon OH, Leung SY, Ko TY et al. · 2026 · Cureus
Background and purpose Contrast-enhanced mammography (CEM) has emerged as a valuable imaging modality for breast cancer detection and management. Background parenchymal enhancement (BPE) reflects the level of normal glandular tissue…
View details →DOI: 10.7759/cureus.107590 Negative / Null Result Report
Jang M, Kwon S · 2026 · Preprint
Abstract Background The WTO TRIPS flexibilities serve as a health safeguard that protects access to medicines (ATM) by allowing flexibility in pharmaceutical patents. Engaging with state and capital powers, civil society organizations…
View details →DOI: 10.21203/rs.3.rs-8018356/v1 Negative / Null Result ReportOpen access
V. Oliveira, R. B. D. Silva, A. Veloso et al. · 2024 · Semina: Ciências Agrárias
The objective of this study was to compare the response of Urochloa decumbens cv. Basilisk pastures in monoculture and silvopastoral systems (SPS), and to determine the most suitable pre-defoliation canopy height for managing this species…
View details →DOI: 10.5433/1679-0359.2024v45n4p1081 Negative / Null Result ReportOpen accessMedicine
Van Dyken PC, Yang K, Faria AV et al. · 2025 · Biological psychiatry global open science
Background White matter alterations observed using diffusion weighted imaging have become a hallmark of chronic schizophrenia, but it is unclear when these changes arise over the course of the disease. Nearly all studies reported to date…
View details →DOI: 10.1016/j.bpsgos.2025.100472 Negative / Null Result ReportMedicine
Mc Caughey, Gustainis, Ambrosio et al. · 2026 · Ultrasound quarterly
This study evaluates whether contrast-enhanced ultrasound (CEUS) serves as an effective next-step imaging modality for patients with end-stage renal disease (ESRD) who have indeterminate renal lesions on computed tomography (CT), assessing…
View details →DOI: 10.1097/ruq.0000000000000749 Negative / Null Result ReportMedicine
Orhan B, Nauta M · 2026 · Death studies
Meaning Management Theory suggests that engaging with meaning-related resources helps individuals constructively regulate consciously experienced death anxiety. Consistent with that theory, we tested whether a single-session, online…
View details →DOI: 10.1080/07481187.2026.2659888 Negative / Null Result ReportOpen accessComputer Science
Felix Krejca, Tobias Kietreiber, Alexander Buchelt et al. · 2025 · arXiv
The increasing volume of online discussions requires advanced automatic content moderation to maintain responsible discourse. While hate speech detection on social media is well-studied, research on German-language newspaper forums remains limited. Existing studies often neglect platform-specific context, such as user history and article themes. This paper addresses this gap by developing and evaluating binary classification models for automatic content moderation in German newspaper forums, incorporating contextual information. Using LSTM, CNN, and ChatGPT-3.5 Turbo, and leveraging the One Mi
Negative / Null Result Report
Matziorinis AM, Gaser C, Koelsch S · 2022 · Preprint
Music-making and engagement in music-related activities have shown procognitive benefits for healthy and pathological populations, suggesting reductions in brain aging. A previous brain aging study, using Brain Age Gap Estimation…
View details →DOI: 10.21203/rs.3.rs-1991605/v1 Negative / Null Result ReportOpen accessComputer Science
Weronika Ormaniec, Michael Vollenweider, Elisa Hoskovec · 2025 · arXiv
In this paper, we explore the idea of combining GCNs into one model. To that end, we align the weights of different models layer-wise using optimal transport (OT). We present and evaluate three types of transportation costs and show that the studied fusion method consistently outperforms the performance of vanilla averaging. Finally, we present results suggesting that model fusion using OT is harder in the case of GCNs than MLPs and that incorporating the graph structure into the process does not improve the performance of the method.
Negative / Null Result ReportOpen accessPediatrics
Mohamad A. Alanbari, Mohamad A. Alanbari, Hebah M. Hamdan et al. · 2024 · Frontiers in Pediatrics
Background/AimManaging young children with negative behaviors can be challenging in dental settings. Moderate sedation (MS) is often used as a treatment option for such children. However, children's behavior during MS may vary depending on several variables. These variables include parental factors, such as parental anxiety, coping strategies, and pain catastrophizing. However, this area, particularly in Saudi Arabia, remains underexplored. Therefore, this study aimed to assess the association among parental anxiety, coping style, pain catastrophizing, and children's behavior during MS among S
View details →DOI: 10.3389/fped.2024.1456395 