Negative / Null Result ReportMedicine
Hirose R, Matsuura K, Ii Y et al. · 2026 · Journal of neural transmission (Vienna, Austria : 1996)
In Parkinson's disease (PD), neuronal loss occurs in the substantia nigra (SN) and locus coeruleus (LC). Previous studies using neuromelanin-sensitive magnetic resonance imaging (NMI) at 3T MRI have described the measurement methods and…
View details →DOI: 10.1007/s00702-026-03179-z Negative / Null Result ReportOpen accessMedicine
Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research
Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…
View details →DOI: 10.4258/hir.2026.32.1.14 Negative / Null Result Report
Samal DR, Mendiratta P · 2026 · Preprint
Abstract The CoViD situation globally tested the efficacy of health infrastructure as well as the administrative management of urban areas. This study focuses on the impact of the CoViD-19 pandemic across the nine municipal corporations in…
View details →DOI: 10.21203/rs.3.rs-8799985/v1 Failed Experiment ReportMedicine
Sekmen S, Hursoy N, Panc K et al. · 2026 · Clinical imaging
Aim This study aims to explore the correlation between background parenchymal enhancement (BPE) observed in breast magnetic resonance imaging (MRI) and the presence of breast cancer. Materials and methods A total of 761 patients (326…
View details →DOI: 10.1016/j.clinimag.2025.110680 Negative / Null Result Report
· 2025 · European Journal of Clinical Pharmacy
Pediatric nephrolithiasis is an increasing concern and often requires complete stone clearance due to high recurrence risk. Managing large renal stones (>2 cm), lower calyceal stones (>1 cm), and stones refractory to Extracorporeal Shock…
View details →DOI: 10.61336/ejcp/25-08-441 Negative / Null Result ReportMedicine
Grunert M, Horn V, Baudrexl JC et al. · 2026 · European journal of radiology
Background Progressive fibrosing interstitial lung diseases (ILD) continue to have a poor prognosis. To date, there is no imaging method that can reliably detect fibrotic remodeling processes or distinguish between active and dormant…
View details →DOI: 10.1016/j.ejrad.2026.113036 Negative / Null Result ReportMedicine
Jiang C, Cheng P, Liu Y et al. · 2025 · Journal of pediatric orthopedics
Introduction Imaging-based measurement indices of patellar height are essential for diagnosing patella alta in children and adolescents. The Patellotrochlear Index (PTI) measures the cartilaginous anatomy which is crucial for identifying…
View details →DOI: 10.1097/bpo.0000000000003057 Negative / Null Result Report
Armi S, Abharian PH, Barzkar F et al. · 2026 · Preprint
Abstract Introduction: Mild cognitive impairment (MCI), often misattributed to normal aging, commonly precedes dementia, highlighting the critical need for early identification to enable timely intervention and management. Objective: This…
View details →DOI: 10.21203/rs.3.rs-9918242/v1 Replication FailureMedicine
Vukšić J, Kustić D · 2026 · Rheumatology international
To examine whether salivary gland ultrasonography (SGUS) and scintigraphy (SGS) reflect systemic disease activity (ESSDAI) and patient-reported index (ESSPRI) in primary Sjögren's disease (PSD). We retrospectively enrolled 118 patients…
View details →DOI: 10.1007/s00296-026-06132-1 Negative / Null Result Report
Chen J, Li X, Tian Z et al. · 2026 · Preprint
Abstract Objective To investigate the structural basis of white matter fiber tracts in cognitive dysfunction following radiochemotherapy in patients with frontal lobe glioma. Methods A total of 40 patients with frontal lobe glioma who…
View details →DOI: 10.21203/rs.3.rs-9225199/v1 Negative / Null Result ReportOpen accessMedicine
Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine
Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…
View details →DOI: 10.1186/s12890-026-04326-8 Negative / Null Result ReportMedicine
Kużdżał A, Gambuś K, Moszczyński K et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Positron emission tomography (PET) using 18-fluorodeoxyglucose (18-FDG) is the primary imaging modality for mediastinal staging of lung cancer. Higher standardized uptake value (SUVmax) reportedly correlates with more aggressive…
View details →DOI: 10.17219/acem/210368 Negative / Null Result Report
shoabjareh ME, Ansari-Astaneh M, Shoeibi N et al. · 2026 · Preprint
Abstract Background This study evaluated choroidal thickness in healthy Iranian individuals using enhanced depth imaging optical coherence tomography (EDI-OCT) and evaluated its correlation with demographic characteristics, laboratory test…
View details →DOI: 10.21203/rs.3.rs-9727938/v1 Negative / Null Result Report
Uchechi Vanessa Alintah-Abel, Francisca Nkachukwu Okeke, Eucharia Chika Enebe · 2025 · British Journal of Multidisciplinary and Advanced Studies
The goal of most countries is the desire to maintain a stable price level of goods and services. This however, appears to be an uphill task given the incidence of subsidy removal that is presently ravaging the developing economies of the…
View details →DOI: 10.37745/bjmas.2022.04253 Negative / Null Result ReportMedicine
Brandtzäg AA, Eiberg JP, Taudorf M et al. · 2026 · EJVES vascular forum
Introduction To evaluate intra-arterial pressure measurement (IAPM) in relation to pre- and intra-operative diagnostic methods for assessing superior mesenteric artery (SMA) stenosis in patients with a diagnosis of chronic mesenteric…
View details →DOI: 10.1016/j.ejvsvf.2026.03.001 Negative / Null Result ReportMedicine
Smeulders N, Gaze MN, Guérin F et al. · 2026 · Journal of pediatric surgery
Background Risk stratification of rhabdomyosarcoma (RMS) requires accurate staging, with histological nodal assessment being of critical importance for specific tumour sites. This report explores the value of surgical nodal staging in…
View details →DOI: 10.1016/j.jpedsurg.2026.163162 Negative / Null Result ReportOpen accessMedicine
Soumboundou SM, Ndiaye ML, Ndiaye R et al. · 2026 · Cureus
Introduction The advent of 3D imaging has created a significant opportunity to enhance the accuracy of age estimation. By utilizing 3D segmentation, it is now possible to evaluate the three-dimensional pulp volume as an indicator of age.…
View details →DOI: 10.7759/cureus.109325 Negative / Null Result Report
Benmoussa H, Barkani ME, Khodriss C et al. · 2026 · Preprint
Abstract Background: Dry eye disease is the most common ophthalmological manifestation in patients with rheumatoid arthritis (RA). Its diagnosis relies on clinical parameters and non-invasive imaging techniques. The aim of this study was…
View details →DOI: 10.21203/rs.3.rs-9248654/v1 Negative / Null Result ReportMedicine
Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…
View details →DOI: 10.3174/ajnr.a9056 Negative / Null Result ReportOpen accessMedicine
Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery
Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…
View details →DOI: 10.1097/moo.0000000000001102 Negative / Null Result ReportOpen accessPhysics
Tim Gould · 2012 · arXiv
The "ACFD-RPA" correlation energy functional has been widely applied to a variety of systems to successfully predict energy differences, and less successfully predict absolute correlation energies. Here we present a parameter-free exchange-correlation kernel that systematically improves absolute correlation energies, while maintaining most of the good numerical properties that make the ACFD-RPA numerically tractable. The "RXH" kernel is constructed to approximate the true exchange kernel via a carefully weighted, easily computable radial averaging. Correlation energy errors of atoms with two t
Negative / Null Result ReportOpen accessComputer Science
John T. Holodnak, Allan B. Wollaber · 2021 · arXiv
Multiple techniques for producing calibrated predictive probabilities using deep neural networks in supervised learning settings have emerged that leverage approaches to ensemble diverse solutions discovered during cyclic training or training from multiple random starting points (deep ensembles). However, only a limited amount of work has investigated the utility of exploring the local region around each diverse solution (posterior mode). Using three well-known deep architectures on the CIFAR-10 dataset, we evaluate several simple methods for exploring local regions of the weight space with re
Negative / Null Result ReportOpen accessMedicine
Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research
Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…
View details →DOI: 10.1002/jfa2.70155 Negative / Null Result ReportOpen accessMedicine
Van Dyken PC, Yang K, Faria AV et al. · 2025 · Biological psychiatry global open science
Background White matter alterations observed using diffusion weighted imaging have become a hallmark of chronic schizophrenia, but it is unclear when these changes arise over the course of the disease. Nearly all studies reported to date…
View details →DOI: 10.1016/j.bpsgos.2025.100472 Negative / Null Result Report
Zeng Y, Zhu Y, Liu W et al. · 2026 · Preprint
Abstract Background When the function of one kidney is impaired or lost, the contralateral kidney may exhibit varying degrees of compensatory response. However, the influencing factors and underlying mechanisms of renal compensation remain…
View details →DOI: 10.21203/rs.3.rs-9853817/v1 Negative / Null Result ReportOpen accessComputer Science
Zhen Xuen Brandon Low, Rory Zhang, Hang Min et al. · 2025 · arXiv
Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and subject to moderate inter-rater reliability, while existing automated deep learning models have moderate performance and typically fail to generalize across diverse clinical and research MRI datasets. We adapted MedNeXt-L-k5, a Transformer-inspired 3D encoder-decoder convolutional network, for automated PVS segmentation. Two models were trained: one using a homog
Negative / Null Result ReportMedicine
Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…
View details →DOI: 10.23736/s1824-4785.26.03686-1 Negative / Null Result Report
Matziorinis AM, Gaser C, Koelsch S · 2022 · Preprint
Music-making and engagement in music-related activities have shown procognitive benefits for healthy and pathological populations, suggesting reductions in brain aging. A previous brain aging study, using Brain Age Gap Estimation…
View details →DOI: 10.21203/rs.3.rs-1991605/v1 Negative / Null Result ReportMedicine
Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →DOI: 10.1016/j.jisako.2026.101134 Negative / Null Result ReportOpen accessEngineering
Arjun D. Desai, Francesco Caliva, Claudia Iriondo et al. · 2020 · arXiv
Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D knee MRI from 88 subjects at two timepoints with ground-truth articular (femoral, tibial, patellar) cartilage and meniscus segmentations was standardized. Challenge submissions and a majority-vote ensemble were evaluated using Dice score, average symmetric surface distance, volumetric overlap error, and coefficient of variation on a hold-out test set. Simil
