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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

757 results for "aging" · page 11 of 26

Negative / Null Result ReportMedicine

Magnetic resonance imaging-derived anterior tibial translation after anterior cruciate ligament reconstruction and its association with postoperative adverse events: A retrospective cohort study.

Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine

Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…

View details →DOI: 10.1016/j.jisako.2026.101134
Negative / Null Result ReportOpen accessEngineering

The International Workshop on Osteoarthritis Imaging Knee MRI Segmentation Challenge: A Multi-Institute Evaluation and Analysis Framework on a Standardized Dataset

Arjun D. Desai, Francesco Caliva, Claudia Iriondo et al. · 2020 · arXiv

Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D knee MRI from 88 subjects at two timepoints with ground-truth articular (femoral, tibial, patellar) cartilage and meniscus segmentations was standardized. Challenge submissions and a majority-vote ensemble were evaluated using Dice score, average symmetric surface distance, volumetric overlap error, and coefficient of variation on a hold-out test set. Simil

Negative / Null Result ReportMedicine

The Association Between the STOP-Bang Score and the Integrated Pulmonary Index in Patients Undergoing Endobronchial Ultrasound with Sedation: The STOP OSA-IPI Cohort Study.

Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…

View details →DOI: 10.3390/medicina62061034
Replication FailureMedicine

Imaging correlates of disease activity and patient-reported symptoms in primary Sjögren's disease: an ultrasonographic and scintigraphic study.

Vukšić J, Kustić D · 2026 · Rheumatology international

To examine whether salivary gland ultrasonography (SGUS) and scintigraphy (SGS) reflect systemic disease activity (ESSDAI) and patient-reported index (ESSPRI) in primary Sjögren's disease (PSD). We retrospectively enrolled 118 patients…

View details →DOI: 10.1007/s00296-026-06132-1
Negative / Null Result ReportOpen accessComputer Science

Honey, I shrunk the scientist -- Evaluating 2D, 3D, and VR interfaces for navigating samples under the microscope

Jan Tiemann, Matthew McGinity, Ulrik Günther · 2026 · arXiv

In contemporary biology and medicine, 3D microscopy is one of the most widely-used techniques for imaging and manipulation of various kinds of samples. Navigating such a micrometer-sized, 3-dimensional sample under the microscope -- e.g. to find relevant imaging regions -- can pose a tedious challenge for the experimenter. In this paper, we examine whether 2D desktop, 3D desktop, or Virtual Reality (VR) interfaces provide the best user experience and performance for the exploration of 3D samples. We invited 12 skilled microscope operators to perform two different exploration tasks in 2D, 3D an

Negative / Null Result ReportMedicine

Assessment of active fibrotic remodeling in patients with idiopathic pulmonary fibrosis (IPF)/progressive pulmonary fibrosis (PPF) using dual-time-point [<sup>68</sup>Ga]Ga-FAPI-46-PET/CT.

Grunert M, Horn V, Baudrexl JC et al. · 2026 · European journal of radiology

Background Progressive fibrosing interstitial lung diseases (ILD) continue to have a poor prognosis. To date, there is no imaging method that can reliably detect fibrotic remodeling processes or distinguish between active and dormant…

View details →DOI: 10.1016/j.ejrad.2026.113036
Negative / Null Result Report

Effect of remote surveillance system on management of diagnostic imaging significant actionable findings.

Jose A. Rivera, Carmen E. Gonzalez, Tonita Bates · 2024 · JCO Oncology Practice

327 Background: Delayed assessment of diagnostic imaging (DI) significant actionable findings (AFs) at an oncological center prompted the creation of a safety net system which used technological advancements to improve communication…

View details →DOI: 10.1200/op.2024.20.10_suppl.327
Negative / Null Result ReportMedicine

An Occupation-Focused Intervention to Promote Functioning Among Adults Aging With Diabetes and Heart Disease.

Mirza M, Fischer H, Arias D · 2026 · OTJR : occupation, participation and health

Background Aging adults with chronic diseases are at risk of functional decline. Objectives This pilot randomized control trial examined the feasibility, acceptability, and preliminary efficacy of an occupational therapy intervention to…

View details →DOI: 10.1177/15394492261446563
Negative / Null Result ReportMedicine

Exploring the Association of Religion and Religiosity on Mammography Screening Among White and Black Women: Results from the Brazilian Longitudinal Study of Aging (Elsi-Brazil).

Dias CS Jr, Verona AP, Leocádio V · 2026 · Journal of religion and health

This study examines the relationship between religious denomination, religious attendance, and mammography screening among White and Black women in Brazil, using baseline data from the Brazilian Longitudinal Study of Aging (ELSI-Brazil,…

View details →DOI: 10.1007/s10943-026-02694-3
Negative / Null Result ReportMedicine

Clinical Characteristics and Long-Term Outcomes of Atypical Choroid Plexus Papillomas: A Single-Center Experience of 40 Cases.

Zuo P, Jiang K, Zou W et al. · 2026 · Neurosurgery

Background and objectives Atypical choroid plexus papillomas (ACPPs) are exceedingly uncommon. The treatment strategies for managing this condition remain a topic of debate. The main aim of this study was to elucidate the clinical features…

View details →DOI: 10.1227/neu.0000000000004026
Negative / Null Result ReportMedicine

Is postoperative routine thoracic imaging necessary to detect thoracic complications in patients undergoing supracostal mini percutaneous nephrolithotomy (m-PCNL) surgery?

Esmeray A, Yazili HB, Gelmis M et al. · 2026 · The Canadian journal of urology

Objectives Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity…

View details →DOI: 10.32604/cju.2025.069657
Negative / Null Result ReportMedicine

Evaluating the Impact of Ursodeoxycholic Acid on Hepatic Clearance of [<sup>99m</sup>Tc]Tc-Sestamibi: A Randomized Controlled Trial to Improve Myocardial Perfusion Imaging.

Hosseinzadeh E, Arefnia M, Bayat M et al. · 2026 · Cancer biotherapy & radiopharmaceuticals

Background Intense hepatobiliary uptake of [ 99m Tc]Tc-sestamibi in myocardial perfusion scintigraphy (MPS) often degrades image quality by obscuring the inferior myocardial wall, leading to equivocal studies. While nonpharmacological…

View details →DOI: 10.1177/10849785251376736
Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Optimizing fMRI Data Acquisition for Decoding Natural Speech with Limited Participants

Louis Jalouzot, Alexis Thual, Yair Lakretz et al. · 2025 · arXiv

We investigate optimal strategies for decoding perceived natural speech from fMRI data acquired from a limited number of participants. Leveraging Lebel et al. (2023)'s dataset of 8 participants, we first demonstrate the effectiveness of training deep neural networks to predict LLM-derived text representations from fMRI activity. Then, in this data regime, we observe that multi-subject training does not improve decoding accuracy compared to single-subject approach. Furthermore, training on similar or different stimuli across subjects has a negligible effect on decoding accuracy. Finally, we fin

Negative / Null Result ReportOpen accessMedicine

Difference in Background Parenchymal Enhancement on Contrast-Enhanced Mammography in Treatment-Naïve Versus Systemic Neoadjuvant Chemotherapy Patients.

Hoon OH, Leung SY, Ko TY et al. · 2026 · Cureus

Background and purpose Contrast-enhanced mammography (CEM) has emerged as a valuable imaging modality for breast cancer detection and management. Background parenchymal enhancement (BPE) reflects the level of normal glandular tissue…

View details →DOI: 10.7759/cureus.107590
Negative / Null Result ReportMedicine

Outcomes from a structured conflict management programme implemented at three paediatric healthcare sites: a mixed-methods evaluation.

Phillipson J, Menson E, Barclay S et al. · 2026 · Archives of disease in childhood

Objective Evaluation of the Medical Mediation Foundation's Conflict Management Programme (CMP)-a structured process for managing conflict. Design Mixed-methods evaluation using Kirkpatrick's framework, a four-level model for evaluating…

View details →DOI: 10.1136/archdischild-2025-329335
Negative / Null Result ReportOpen access

Pre-defoliation canopy height for signal grass ‘Basilisk’ in silvopastoral systems

V. Oliveira, R. B. D. Silva, A. Veloso et al. · 2024 · Semina: Ciências Agrárias

The objective of this study was to compare the response of Urochloa decumbens cv. Basilisk pastures in monoculture and silvopastoral systems (SPS), and to determine the most suitable pre-defoliation canopy height for managing this species…

View details →DOI: 10.5433/1679-0359.2024v45n4p1081
Negative / Null Result Report

Differential Effects of Cultural Performing Arts on Anti-Aging Biomarkers and Well-Being: A Non- Randomized Pre–Post Comparative Study of Traditional Noh/Kyogen and Comedy

Tomisawa T, Nanashima N, In N et al. · 2026 · Preprint

Abstract This study examined how cultural performing arts affect psychological well-being and stress-related biomarkers, comparing traditional Japanese Noh and Kyogen (TNKP) with live comedy (CLP). Participants aged 18–64 years were…

View details →DOI: 10.21203/rs.3.rs-9490822/v1
Negative / Null Result ReportOpen accessComputer Science

Context-Aware Content Moderation for German Newspaper Comments

Felix Krejca, Tobias Kietreiber, Alexander Buchelt et al. · 2025 · arXiv

The increasing volume of online discussions requires advanced automatic content moderation to maintain responsible discourse. While hate speech detection on social media is well-studied, research on German-language newspaper forums remains limited. Existing studies often neglect platform-specific context, such as user history and article themes. This paper addresses this gap by developing and evaluating binary classification models for automatic content moderation in German newspaper forums, incorporating contextual information. Using LSTM, CNN, and ChatGPT-3.5 Turbo, and leveraging the One Mi

Negative / Null Result ReportOpen accessComputer Science

Fusion of Graph Neural Networks via Optimal Transport

Weronika Ormaniec, Michael Vollenweider, Elisa Hoskovec · 2025 · arXiv

In this paper, we explore the idea of combining GCNs into one model. To that end, we align the weights of different models layer-wise using optimal transport (OT). We present and evaluate three types of transportation costs and show that the studied fusion method consistently outperforms the performance of vanilla averaging. Finally, we present results suggesting that model fusion using OT is harder in the case of GCNs than MLPs and that incorporating the graph structure into the process does not improve the performance of the method.

Negative / Null Result ReportOpen accessPediatrics

Association between parental factors and child's behaviors during moderate sedation in pediatric dental care

Mohamad A. Alanbari, Mohamad A. Alanbari, Hebah M. Hamdan et al. · 2024 · Frontiers in Pediatrics

Background/AimManaging young children with negative behaviors can be challenging in dental settings. Moderate sedation (MS) is often used as a treatment option for such children. However, children's behavior during MS may vary depending on several variables. These variables include parental factors, such as parental anxiety, coping strategies, and pain catastrophizing. However, this area, particularly in Saudi Arabia, remains underexplored. Therefore, this study aimed to assess the association among parental anxiety, coping style, pain catastrophizing, and children's behavior during MS among S

View details →DOI: 10.3389/fped.2024.1456395