Abandoned Hypothesis
Valerie Keller · 2023 · Frontiers in Sociology
This article explored the ways in which living with dementia brings potentials to queer the concept of “successful aging” and associated notions of being human. Regarding the progressive development of dementia, it can be assumed that…
View details →DOI: 10.3389/fsoc.2023.1139271 Negative / Null Result ReportMedicine
Schneider BS, Pfaehler CD, Hao KA et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons
Background Although os acromiale is often noted on preoperative imaging in patients undergoing reverse total shoulder arthroplasty (rTSA), its clinical significance is ill-defined. The purpose of this study was to compare the clinical…
View details →DOI: 10.5435/jaaos-d-25-00614 Failed Experiment Report
Ariane Kovac · 2024 · AЯGOS
Divine healing is an emotionally and theologically conflictive field where actors communicate positions and draw boundaries by engaging in certain practices and renouncing others. In this article, I analyse how a progressive evangelical…
View details →DOI: 10.26034/fr.argos.2024.6205 Negative / Null Result ReportMedicine
Kluckner M, Hitzl W, Enzmann FK et al. · 2026 · Journal of clinical medicine
Background/Objectives : Hyperspectral imaging (HSI) facilitates noninvasive assessment of tissue perfusion in patients with peripheral arterial disease. However, available studies are either based on small cohorts and provide no comparison…
View details →DOI: 10.3390/jcm15041667 Negative / Null Result ReportMedicine
Hirose R, Matsuura K, Ii Y et al. · 2026 · Journal of neural transmission (Vienna, Austria : 1996)
In Parkinson's disease (PD), neuronal loss occurs in the substantia nigra (SN) and locus coeruleus (LC). Previous studies using neuromelanin-sensitive magnetic resonance imaging (NMI) at 3T MRI have described the measurement methods and…
View details →DOI: 10.1007/s00702-026-03179-z Negative / Null Result Report
Samal DR, Mendiratta P · 2026 · Preprint
Abstract The CoViD situation globally tested the efficacy of health infrastructure as well as the administrative management of urban areas. This study focuses on the impact of the CoViD-19 pandemic across the nine municipal corporations in…
View details →DOI: 10.21203/rs.3.rs-8799985/v1 Negative / Null Result Report
· 2025 · European Journal of Clinical Pharmacy
Pediatric nephrolithiasis is an increasing concern and often requires complete stone clearance due to high recurrence risk. Managing large renal stones (>2 cm), lower calyceal stones (>1 cm), and stones refractory to Extracorporeal Shock…
View details →DOI: 10.61336/ejcp/25-08-441 Negative / Null Result ReportMedicine
Grunert M, Horn V, Baudrexl JC et al. · 2026 · European journal of radiology
Background Progressive fibrosing interstitial lung diseases (ILD) continue to have a poor prognosis. To date, there is no imaging method that can reliably detect fibrotic remodeling processes or distinguish between active and dormant…
View details →DOI: 10.1016/j.ejrad.2026.113036 Negative / Null Result ReportMedicine
Jiang C, Cheng P, Liu Y et al. · 2025 · Journal of pediatric orthopedics
Introduction Imaging-based measurement indices of patellar height are essential for diagnosing patella alta in children and adolescents. The Patellotrochlear Index (PTI) measures the cartilaginous anatomy which is crucial for identifying…
View details →DOI: 10.1097/bpo.0000000000003057 Replication FailureMedicine
Vukšić J, Kustić D · 2026 · Rheumatology international
To examine whether salivary gland ultrasonography (SGUS) and scintigraphy (SGS) reflect systemic disease activity (ESSDAI) and patient-reported index (ESSPRI) in primary Sjögren's disease (PSD). We retrospectively enrolled 118 patients…
View details →DOI: 10.1007/s00296-026-06132-1 Negative / Null Result Report
shoabjareh ME, Ansari-Astaneh M, Shoeibi N et al. · 2026 · Preprint
Abstract Background This study evaluated choroidal thickness in healthy Iranian individuals using enhanced depth imaging optical coherence tomography (EDI-OCT) and evaluated its correlation with demographic characteristics, laboratory test…
View details →DOI: 10.21203/rs.3.rs-9727938/v1 Negative / Null Result Report
Uchechi Vanessa Alintah-Abel, Francisca Nkachukwu Okeke, Eucharia Chika Enebe · 2025 · British Journal of Multidisciplinary and Advanced Studies
The goal of most countries is the desire to maintain a stable price level of goods and services. This however, appears to be an uphill task given the incidence of subsidy removal that is presently ravaging the developing economies of the…
View details →DOI: 10.37745/bjmas.2022.04253 Negative / Null Result ReportMedicine
Brandtzäg AA, Eiberg JP, Taudorf M et al. · 2026 · EJVES vascular forum
Introduction To evaluate intra-arterial pressure measurement (IAPM) in relation to pre- and intra-operative diagnostic methods for assessing superior mesenteric artery (SMA) stenosis in patients with a diagnosis of chronic mesenteric…
View details →DOI: 10.1016/j.ejvsvf.2026.03.001 Negative / Null Result ReportMedicine
Mirza M, Fischer H, Arias D · 2026 · OTJR : occupation, participation and health
Background Aging adults with chronic diseases are at risk of functional decline. Objectives This pilot randomized control trial examined the feasibility, acceptability, and preliminary efficacy of an occupational therapy intervention to…
View details →DOI: 10.1177/15394492261446563 Negative / Null Result ReportOpen accessMedicine
Soumboundou SM, Ndiaye ML, Ndiaye R et al. · 2026 · Cureus
Introduction The advent of 3D imaging has created a significant opportunity to enhance the accuracy of age estimation. By utilizing 3D segmentation, it is now possible to evaluate the three-dimensional pulp volume as an indicator of age.…
View details →DOI: 10.7759/cureus.109325 Negative / Null Result ReportMedicine
Zuo P, Jiang K, Zou W et al. · 2026 · Neurosurgery
Background and objectives Atypical choroid plexus papillomas (ACPPs) are exceedingly uncommon. The treatment strategies for managing this condition remain a topic of debate. The main aim of this study was to elucidate the clinical features…
View details →DOI: 10.1227/neu.0000000000004026 Negative / Null Result ReportMedicine
Esmeray A, Yazili HB, Gelmis M et al. · 2026 · The Canadian journal of urology
Objectives Supracostal access during percutaneous nephrolithotomy (PCNL) increases the risk of pulmonary complications. Although routine postoperative thoracic imaging is commonly performed to detect these events, its clinical necessity…
View details →DOI: 10.32604/cju.2025.069657 Negative / Null Result ReportMedicine
Hosseinzadeh E, Arefnia M, Bayat M et al. · 2026 · Cancer biotherapy & radiopharmaceuticals
Background Intense hepatobiliary uptake of [ 99m Tc]Tc-sestamibi in myocardial perfusion scintigraphy (MPS) often degrades image quality by obscuring the inferior myocardial wall, leading to equivocal studies. While nonpharmacological…
View details →DOI: 10.1177/10849785251376736 Negative / Null Result Report
Benmoussa H, Barkani ME, Khodriss C et al. · 2026 · Preprint
Abstract Background: Dry eye disease is the most common ophthalmological manifestation in patients with rheumatoid arthritis (RA). Its diagnosis relies on clinical parameters and non-invasive imaging techniques. The aim of this study was…
View details →DOI: 10.21203/rs.3.rs-9248654/v1 Negative / Null Result ReportMedicine
Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…
View details →DOI: 10.3174/ajnr.a9056 Negative / Null Result ReportOpen accessPhysics
Tim Gould · 2012 · arXiv
The "ACFD-RPA" correlation energy functional has been widely applied to a variety of systems to successfully predict energy differences, and less successfully predict absolute correlation energies. Here we present a parameter-free exchange-correlation kernel that systematically improves absolute correlation energies, while maintaining most of the good numerical properties that make the ACFD-RPA numerically tractable. The "RXH" kernel is constructed to approximate the true exchange kernel via a carefully weighted, easily computable radial averaging. Correlation energy errors of atoms with two t
Negative / Null Result ReportMedicine
Phillipson J, Menson E, Barclay S et al. · 2026 · Archives of disease in childhood
Objective Evaluation of the Medical Mediation Foundation's Conflict Management Programme (CMP)-a structured process for managing conflict. Design Mixed-methods evaluation using Kirkpatrick's framework, a four-level model for evaluating…
View details →DOI: 10.1136/archdischild-2025-329335 Negative / Null Result ReportOpen accessComputer Science
John T. Holodnak, Allan B. Wollaber · 2021 · arXiv
Multiple techniques for producing calibrated predictive probabilities using deep neural networks in supervised learning settings have emerged that leverage approaches to ensemble diverse solutions discovered during cyclic training or training from multiple random starting points (deep ensembles). However, only a limited amount of work has investigated the utility of exploring the local region around each diverse solution (posterior mode). Using three well-known deep architectures on the CIFAR-10 dataset, we evaluate several simple methods for exploring local regions of the weight space with re
Negative / Null Result ReportOpen accessMedicine
Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research
Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…
View details →DOI: 10.1002/jfa2.70155 Negative / Null Result Report
Zeng Y, Zhu Y, Liu W et al. · 2026 · Preprint
Abstract Background When the function of one kidney is impaired or lost, the contralateral kidney may exhibit varying degrees of compensatory response. However, the influencing factors and underlying mechanisms of renal compensation remain…
View details →DOI: 10.21203/rs.3.rs-9853817/v1 Negative / Null Result Report
Tomisawa T, Nanashima N, In N et al. · 2026 · Preprint
Abstract This study examined how cultural performing arts affect psychological well-being and stress-related biomarkers, comparing traditional Japanese Noh and Kyogen (TNKP) with live comedy (CLP). Participants aged 18–64 years were…
View details →DOI: 10.21203/rs.3.rs-9490822/v1 Negative / Null Result ReportOpen accessComputer Science
Zhen Xuen Brandon Low, Rory Zhang, Hang Min et al. · 2025 · arXiv
Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and subject to moderate inter-rater reliability, while existing automated deep learning models have moderate performance and typically fail to generalize across diverse clinical and research MRI datasets. We adapted MedNeXt-L-k5, a Transformer-inspired 3D encoder-decoder convolutional network, for automated PVS segmentation. Two models were trained: one using a homog
Negative / Null Result ReportMedicine
Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…
View details →DOI: 10.23736/s1824-4785.26.03686-1 Negative / Null Result ReportMedicine
Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →DOI: 10.1016/j.jisako.2026.101134 Negative / Null Result ReportOpen accessEngineering
Arjun D. Desai, Francesco Caliva, Claudia Iriondo et al. · 2020 · arXiv
Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D knee MRI from 88 subjects at two timepoints with ground-truth articular (femoral, tibial, patellar) cartilage and meniscus segmentations was standardized. Challenge submissions and a majority-vote ensemble were evaluated using Dice score, average symmetric surface distance, volumetric overlap error, and coefficient of variation on a hold-out test set. Simil