11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Shimada H, Lee S, Doi T et al. · 2026 · Gerontology
Introduction Walking speed is widely recognized as an informative indicator of physical capability in later life and is frequently used to evaluate mobility and functional health in older adults. Although the measurement of community…
View details →Rosi Júnior J, Telles JPM, Santana LS et al. · 2026 · Arquivos de neuro-psiquiatria
Background Alpha 1-antitrypsin (A1AT) helps maintain vascular-wall integrity, but its role in the formation and rupture of intracranial aneurysms is unclear. Objective To compare A1AT levels between patients with ruptured and unruptured…
View details →Kavrul Kayaalp G, Balcı MC, Kürkçü Güneş D et al. · 2026 · Cardiology in the young
Background Early identification of familial hypercholesterolaemia is critical to prevent long-term cardiovascular complications. This study assessed diagnostic features and age at diagnosis in children with familial hypercholesterolaemia…
View details →Shinkawa K, Yoshida S, Nakao YM et al. · 2026 · Clinical and experimental nephrology
Introduction The clinical characteristics of patients with nephrotic syndrome undergoing in-hospital rehabilitation are not well-understood, and the effects of exercise on acute kidney injury (AKI) or venous thromboembolism (VTE) in this…
View details →Hakim MS, Hashimi MH, Saeed KM et al. · 2026 · Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
Background Viral hepatitis and HIV infections are common public health concerns among injecting drug users, however, there is limited evidence on their seroprevalence in Afghanistan. Aim To determine the seroprevalence of hepatitis B,…
View details →Popovic R, Cvitanovic S, Sarac I et al. · 2026 · Cureus
Objective To assess parents' knowledge of recommended oral-hygiene practices for children and to describe oral-hygiene behaviors within families (parents and children), as well as factors associated with children's oral-hygiene outcomes.…
View details →Famuyide L, Patel J, Nembhard WN · 2026 · Birth defects research
Background Hypospadias is one of the most common genital defects in boys, affecting about 1 in 125 live-born boys. Several studies have examined the association between a single environmental exposure and risk of hypospadias, but few have…
View details →Ye B, Liu Y, Zhang J et al. · 2026 · Frontiers in nutrition
Background To investigate the associations between consumption of sugar-sweetened beverages (SSBs), artificially sweetened beverages (ASBs), and natural juices (NJs) and incident kidney stone disease (KSD), and to assess whether genetic…
View details →Kılıç A, Koçak Ulucaköy R, Osmanov Z et al. · 2026 · Biomarkers in medicine
Objective Biomarkers that accurately reflect disease activity and inflammatory burden are needed, particularly in the early stages of spondyloarthropathy (SpA). This study aimed to evaluate the association between serum neopterin levels…
View details →Sussadee M, Jarudecha T, Muikaew R et al. · 2026 · Animals : an open access journal from MDPI
Feline hypertrophic cardiomyopathy (HCM) is the most common cardiac disease in cats, causing morbidity and mortality. Recently, a variant in the Alström syndrome protein 1 ( ALMS1 ) gene has been reported to be associated with HCM in…
View details →Choi SJ · 2026 · BMC public health
Background Walking is a widely accessible form of physical activity and has been consistently associated with improved health-related quality of life (HRQoL) at the individual level. However, less is known about how walking participation…
View details →McCaw K, Fink B, Danis D et al. · 2026 · American journal of veterinary research
Objective To compare the accuracy of a tibial plateau-leveling osteotomy (TPLO) using a modular guide (OssAbility) compared to the traditional freehand method. We hypothesized that guide use would improve TPLO centering and accuracy in the…
View details →Gaba K, Kumar K, Kaushik R et al. · 2026 · Cureus
Background The use of post-mortem blood culture as a diagnostic tool in medico-legal autopsies is limited. Differentiating true infection from contamination or post-mortem bacterial translocation remains a challenge. This study aimed to…
View details →Buran A, Altaş H, Özkaya Uçar Y et al. · 2026 · Journal of the Turkish German Gynecological Association
Objective To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and methods This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for…
View details →Braun S, Selkridge I, Nocon A et al. · 2026 · Arthroplasty (London, England)
Background Extensor mechanism disruption following total knee arthroplasty (TKA) significantly impairs knee function and quality of life. Extensor mechanism reconstruction (EMR) is effective but carries risks, including post-operative…
View details →Sarpeleh F, Ehtesham N, Mirjani R et al. · 2026 · Lupus
ObjectiveThe dysfunction of interleukin-7 receptor alpha (IL-7Rα), which is encoded by the IL7RA gene, has been implicated in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the relationship between…
View details →Mazurek A, Jankowski M, Grudziąż-Sękowska J · 2026 · BMC nephrology
BACKGROUND: The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied…
View details →Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research
Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…
View details →Millán J, Gal B, Esquerda M et al. · 2026 · BMC medical education
Background In Spain, access to specialized medical training is determined through a highly competitive national examination (MIR). While the educational climate of medical schools has been associated with students' learning outcomes and…
View details →Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…
View details →Brown J, Abdullah N, Sobuwa S · 2026 · International journal of emergency medicine
BACKGROUND: Endotracheal intubation is a critical life-saving intervention in prehospital emergency care, yet evidence supporting its safe implementation by prehospital practitioners in lower- to middle-income countries remains limited.…
View details →El Habashy HR, Ahmed SM, Al Salmawy DA et al. · 2026 · Neurological research
Background Bell's palsy (BP) is the most common acute peripheral mononeuropathy worldwide. While electrodiagnostic studies are established tools for functional assessment, high-resolution ultrasonography (HRUS) has emerged as a…
View details →Mohan Kumar R, Gomaa AR, Scarffe D et al. · 2026 · Foot (Edinburgh, Scotland)
Introduction Achilles Tendon Ruptures (ATR) in sport has only previously been investigated in an athletic population. Our aim in this study was to understand the psychology and function of ATR and their return to sport. Methods A historic…
View details →Morais RF, Duro D, Pires R et al. · 2026 · Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
Background Emotion perception is the capacity that enables humans to correctly identify the cues that guide interpersonal interactions, forming the basis for social behavior. The parahippocampal cortex may contribute to emotion perception…
View details →Ford LB, Irvine M, Lee H et al. · 2026 · HLA
Mismatched allogeneic haematopoietic stem cell transplants (HSCT) are complicated by the presence of pre-existing HLA-specific antibodies targeting the mismatched HLA antigens (DSAs). Data indicates that the presence of DSAs…
View details →Nithya M, Titiyal R, Ajayababu A et al. · 2026 · Journal of clinical medicine
Background: Obstructive sleep apnea (OSA) is common in individuals with obesity, largely due to increased soft tissue causing upper airway narrowing. However, mechanisms of OSA improvement following weight loss are incompletely understood,…
View details →Soumboundou SM, Ndiaye ML, Ndiaye R et al. · 2026 · Cureus
Introduction The advent of 3D imaging has created a significant opportunity to enhance the accuracy of age estimation. By utilizing 3D segmentation, it is now possible to evaluate the three-dimensional pulp volume as an indicator of age.…
View details →Lee BJ, Kong IJ, Yoon JA · 2026 · Lymphatic research and biology
Purpose To examine the association between clinical severity and lymphatic function of breast cancer-related lymphedema. Methods and results A total of 151 patients with lymphedema after breast cancer-related mastectomy were enrolled. The…
View details →Fedeli L, Magistrelli A, Vaiano A et al. · 2026 · Journal of radiological protection : official journal of the Society for Radiological Protection
The reduction of the annual equivalent dose limit to the lens of the eye from 150 to 20 mSv has increased the need for reliable assessment of occupational eye lens exposure, particularly in interventional radiology. Lens absorbed dose is…
View details →Brandtzäg AA, Eiberg JP, Taudorf M et al. · 2026 · EJVES vascular forum
Introduction To evaluate intra-arterial pressure measurement (IAPM) in relation to pre- and intra-operative diagnostic methods for assessing superior mesenteric artery (SMA) stenosis in patients with a diagnosis of chronic mesenteric…
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