11,412 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lakhsassi L, Borg C, Briken P et al. · 2025 · PloS one
It has been proposed that acute pain can generally be reduced by sexual activity. Increasing subjective sexual arousal might thus help reduce pain during sex. Yet, in conflict with the view that subjective sexual arousal would generally…
View details →Ohmori T, Hiraoka A, Totsugawa T et al. · 2025 · Annals of thoracic surgery short reports
Background It is still controversial whether prosthesis-patient mismatch (PPM) adversely affects long-term outcomes after aortic valve replacement (AVR). The aim of this study was to examine whether flow-adjusted pressure gradient is a…
View details →Yii F, Strang N, Bernabeu MO et al. · 2024 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Introduction Research assuming linearity has concluded that corneal biomechanics are compromised in high myopia. We investigated whether this assumption was appropriate and re-examined these associations across different levels of myopia.…
View details →Ivimey-Cook ER, Shorr S, Moorad JA · 2023 · Evolution; international journal of organic evolution
Maternal senescence is the reduction in individual performance associated with increased maternal age at conception. When manifested on adult lifespan, this phenomenon is known as the "Lansing Effect." Single-species studies report both…
View details →Gharibian D, Medeiros M, Dion PA et al. · 2026 · Tremor and other hyperkinetic movements (New York, N.Y.)
Essential Tremor (ET) is a highly heterogeneous movement disorder with a strong genetic basis. However, the etiology of ET is unclear, largely due to its clinical heterogeneity and frequently observed comorbidities. We conducted a…
View details →Heneghan JA, Akande MY, Ramgopal S et al. · 2024 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To describe change in Functional Status Scale (FSS) associated with critical illness and assess associated development of new morbidities with PICU readmission. Design Retrospective, cross-sectional cohort study using the…
View details →Osias E, Cale M, Saffari P et al. · 2024 · Orbit (Amsterdam, Netherlands)
Purpose To understand how thyroid eye disease (TED) impacts buccal fat pad (BFP) volume. Methods In this cohort study, computed tomography (CT) scans and charts of adult patients with and without TED were obtained from an institutional…
View details →Schuetze BA · 2026 · Cognitive research: principles and implications
A genre of online videos known as "sludge content" has recently surged in popularity. These videos typically present two clips simultaneously, with one primary and one muted secondary video, creating an intentionally overstimulating…
View details →Nair A, Medina J · 2024 · Attention, perception & psychophysics
Our tactile perception is shaped not only by somatosensory input but also by visual information. Prior research on the effect of viewing touch on tactile processing has found higher tactile detection rates when paired with viewed touch…
View details →Stretti F, Parvin R, Fariña Nuñez MT et al. · 2026 · Neurosurgical review
Cranioplasty (CP) is performed after decompressive craniectomy (DC), with complication rates of 15-40%. Risk factors and ideal timing for CP are unclear. This study investigates risk factors for complications after CP and the best time to…
View details →Ratner K, Zhu G, Li Q et al. · 2023 · Journal of adolescence
Introduction Supportive adults are a critical component of effective out-of-school time (OST) youth programs, yet the short-term dynamics that underlie their role are poorly understood. Within GripTape, a US-wide self-driven learning…
View details →Ali HA, Fayi KA, Alkhathami AM et al. · 2023 · International journal of burns and trauma
Burn injuries can lead to a variety of short- and long-term complications, peripheral neuropathy has been known as the most common neuromuscular complication. 29% of the burn-related peripheral neuropathy has been found in both the upper…
View details →Balasundaram P, Avulakunta ID, Delfiner L et al. · 2023 · Case reports in genetics
Arthrogryposis multiplex congenita (AMC) is characterized by nonprogressive symmetric contractures of multiple joints with normal intellect and normal systemic examination. AMC is often due to fetal akinesia, which has neurologic,…
View details →Gonthier C, Gavornikova-Baligand Z · 2023 · Attention, perception & psychophysics
Working memory performance depends on reactivating memory traces, by rapidly switching between refreshing item representations and performing concurrent cognitive processing (time-based resource sharing (TBRS) account). Prior research has…
View details →Wanner A · 2025 · BMJ open respiratory research
The airway wall is thickened in asthma and the airway microvasculature participates in the remodelling. It has been assumed but not convincingly demonstrated that the remodelled airway vasculature has a mechanical role in asthma-associated…
View details →Zhang X, Moran C, Wang R et al. · 2023 · Genes & genomics
Background According to the WHO, about 39% of the global adult population were overweight or obese in 2016. Obesity has high heritability, with more than 1000 variants so far identified. There have been reports indicating that salivary…
View details →Fiszdon JM, Wang K, Lê K et al. · 2024 · Schizophrenia research. Cognition
While cognitive remediation therapy (CRT) and compensatory strategy training both have large literature bases supporting their efficacy on both proximal and distal outcomes, the research base on stand-alone cognitive training (CT) is…
View details →Engoren M, Janda A, Heung M et al. · 2024 · Journal of cardiothoracic and vascular anesthesia
Objectives To estimate whether the association of transfusion and acute kidney injury (AKI) has a threshold of oxygen delivery below which transfusion is beneficial but above which it is harmful. Design Retrospective study SETTING:…
View details →El Sabagh A, Abdulraheem A, Jimenez A et al. · 2026 · JGH open : an open access journal of gastroenterology and hepatology
Background Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) improve glycemic control and promote weight loss but may increase gastric residue, raising concerns during esophagogastroduodenoscopy (EGD). African American patients remain…
View details →Piguet C, Celen Z, Meuleman B et al. · 2025 · Depression and anxiety
Adolescence is marked by major puberty-induced changes including increased reactivity to stress and a peak incidence of mental disorders. The implementation of early interventions during this developmental period is essential to prevent…
View details →Etuk REO, Forestell CA · 2021 · Appetite
Children often struggle to eat the daily recommended servings of fruits and vegetables, and as a result many have poor nutrient intake. This is especially problematic for neophobic children; or those who are hesitant to try new foods.…
View details →de Oliveira RMV, Vasques ACJ, Romero SA et al. · 2026 · European journal of clinical nutrition
Background Inflammatory Bowel Disease (IBD) involves genetic and environmental factors, but the relationship between disease activity, adiposity, and diet remains unclear. Objective To investigate the association between…
View details →Bekkai L, Ibn Majah A, Verset L et al. · 2025 · Diseases (Basel, Switzerland)
Background Olmesartan-induced enteropathy is a rare complication of a widely used angiotensin II receptor blocker. Patients usually present with chronic diarrhea and weight loss. Histologically, villous atrophy and intraepithelial…
View details →Desenzi R, Cuellar CJ, Hoorn QA et al. · 2025 · JDS communications
Pharmacological elevation of cyclic AMP (cAMP) of cultured cumulus-oocyte complexes (COC) before or coincident with initiation of maturation has been reported to improve outcomes for various systems for in vitro production of embryos. Here…
View details →Negen J · 2024 · PloS one
Bayesian reasoning (i.e. prior integration, cue combination, and loss minimization) has emerged as a prominent model for some kinds of human perception and cognition. The major theoretical issue is that we do not yet have a robust way to…
View details →Zhu Z, Feldman G · 2025 · Royal Society open science
Arkes (Arkes 1996 J. Behav. Decis. Mak. 9 , 213-224. (doi:10.1002/(SICI)1099-0771(199609)9:3 3.0.CO;2-1) demonstrated a phenomenon of wastefulness avoidance, showing that people's decisions are impacted by wastefulness, making decisions…
View details →von Spreckelsen P, Wessel I, Glashouwer KA et al. · 2023 · Memory (Hove, England)
People with a negative body image may be more likely to recall negative memories of their body, but also be motivated to avoid retrieving specific memories to prevent triggering aversive emotions (e.g., disgust). Such inclination to retain…
View details →Abu-Saif RA, Al-Basha AS, Al-Younes HM · 2023 · Enfermedades infecciosas y microbiologia clinica (English ed.)
Introduction Simkania negevensis has been linked to some respiratory and non-respiratory diseases. However, there is still a serious lack of clinical investigations that attempt to determine possible body sites that could be inhabited by…
View details →Jin X, Wang J, Du YJ et al. · 2026 · Medicine
Epidemiological evidence suggests that there is an association between systemic lupus erythematosus (SLE), type 1 diabetes (T1D), ankylosing spondylitis (AS), celiac disease (CD), and cognitive impairment (CI). However, the causal…
View details →Fahimi Z, Kazemi M, Rahimi H et al. · 2025 · IBRO neuroscience reports
Background Post-stroke epilepsy (PSE) is a significant complication in stroke survivors, yet early diagnostic biomarkers remain unclear. This study investigated whether circulating microRNA-219 (miR-219) could serve as a reliable biomarker…
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