11,312 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Arık H, Tınazlı M, Süer K · 2026 · Medicina (Kaunas, Lithuania)
Backgroun d and Objectives : Urinary tract infections (UTIs) represent one of the most frequently encountered bacterial infections in clinical practice. Although vitamin D (vit D) is recognised for its immunomodulatory properties, its…
View details →Ramirez De Los Santos ML, Ramírez-De Los Santos S, Becerra Solano LE et al. · 2026 · Nutricion hospitalaria
Introduction Introduction: metabolic syndrome (MS) affects approximately 27 % of the global population and represents a growing public health concern. Identifying factors associated with its presence is essential for prevention, early…
View details →Wang L, Yue Q, Li KQ et al. · 2026 · BMC cancer
Purpose This study aimed to systematically evaluate the associations between oral health conditions, including periodontitis, tooth loss, and dental caries, and colorectal cancer (CRC) risk. Materials and methods PubMed, Embase, the…
View details →Boncyk C, Connell J, Stollings JL et al. · 2026 · Critical care medicine
Objectives ICU patients are at increased risk of inappropriate prescribing and high drug burden. These patients also often experience cognitive impairment, physical disability, and increased mortality after discharge. We investigated…
View details →Ye H, Tian Y, He G et al. · 2026 · Journal of clinical medicine
Objectives : This study aimed to investigate the association between postpartum hemorrhage (PPH) and the risk of postpartum depressive and anxiety symptoms. Methods : A retrospective cohort study of twin delivery was conducted at a…
View details →Jaafari Z, Hassanzadeh J, Sayadi M et al. · 2026 · Health science reports
Background and aims The variation in the incidence of type 2 diabetes mellitus (T2DM) in different countries is associated with various factors. This study aimed to examine the factors linked to the difference in the incidence of T2DM…
View details →Sabri H, Baniameri S, Kataria P et al. · 2026 · Journal of periodontology
Background Periodontitis, a chronic inflammatory disease, is linked to systemic conditions such as cardiovascular and kidney disease. Serum α-Klotho, an anti-aging protein with anti-inflammatory properties, has been associated with…
View details →Hendricks S, Huynh A, Burns DT et al. · 2026 · AIDS research and treatment
Purpose To determine whether sociodemographic factors, including residence in rural/frontier versus urban settings, are associated with differences in HIV viral suppression rates among people living with HIV in Wyoming with one or more…
View details →Xiong Y, Huang J, Wu Y et al. · 2026 · Renal failure
Physical activity (PA) is of great importance for peritoneal dialysis (PD) patients with sarcopenia. However, the optimal PA dose for sarcopenia in PD patients remains unclear. This study adopted a cross-sectional design and enrolled PD…
View details →Luo M, Wang Y, Wang Y et al. · 2026 · The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Objective The optimal interpregnancy interval (IPI) for preventing hypertensive disorders of pregnancy (HDP) remains unclear, and whether this association is modified by maternal baseline characteristics has not been well established. This…
View details →Revilla-León M, Gómez-Polo M, Barmak AB et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem As experience with intraoral scanners (IOSs) and scientific evidence has grown, factors compromising IOS accuracy have been identified. Limited interdental space between tooth preparations lead to the bridge scanning…
View details →Seale L, Bates N, Tumin D et al. · 2026 · European journal of obstetrics, gynecology, and reproductive biology
Objective To examine the association between age at menarche and polycystic ovary syndrome (PCOS) diagnosis among US women aged 20-49 years. Study design Our retrospective cross-sectional analysis used data from the 2022-2023 National…
View details →Wang X, Zhang R, Chai W et al. · 2026 · Medicine
The incidence of IgA nephropathy (IgAN) is increasing, and some observational studies reported the potential correlation of polycystic ovary syndrome (PCOS) with the risk of IgAN. We performed a bidirectional Mendelian randomization…
View details →Gonzalez W, Isla J, Barba D et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Background Anterior tibial translation (ATT) measured on magnetic resonance imaging (MRI) is a reproducible marker of anterior cruciate ligament (ACL) deficiency. However, its longitudinal evolution after ACL reconstruction (ACLR) and its…
View details →Bax EA, Colyn W, Bellemans J et al. · 2026 · Osteoarthritis and cartilage open
Objectives This study investigated the association between alpha angles of the hip and tibial genu varum in a healthy population with equal male-to-female distribution. It also examined sex-based differences, explored the impact of sports…
View details →Motoji Y, Kitamura T, Naito N et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
Objectives This study aimed to investigate changes in haematoma thickness (HT) and the maximum ascending aortic diameter (MAD) early after onset and their association with in-hospital disease progression in type A intramural haematoma…
View details →Izquierdo JA, Kerbel J, Apodaca G et al. · 2026 · Cureus
Background Intraoperative periprosthetic femoral fracture is an uncommon but clinically significant complication of total hip arthroplasty (THA) that may compromise implant stability and increase the risk of early revision surgery. Several…
View details →Wang Y, Zhang Y, Lan Y · 2026 · Scientific reports
The mental health of young people serves as a social barometer, reflecting societal conditions. However, the relationship between social inequality and youth mental health remains a contested issue. This study uses data from the China…
View details →Chen Z, Zhang L, Liang Y et al. · 2026 · Digestive diseases and sciences
Background and aims Post-ESD esophageal stricture remains a major complication despite steroid prophylaxis. Temporary stent placement has been proposed as an adjunctive strategy in high-risk cases, yet its independent effect remains…
View details →Yubaitsa CN, Gani KS, Mitchel M et al. · 2026 · Cureus
Background Musculoskeletal problems in the elderly pose a significant challenge for healthcare providers, as they constitute a vulnerable group. Fractures are often undetected, leading to a reduced quality of life due to increased…
View details →Bastian MB, Kyriakou I, Rosar F et al. · 2026 · The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...
Background Papillary thyroid carcinoma (PTC) with a BRAFV600E mutation is linked to more aggressive tumor characteristics, as well as a higher likelihood of recurrence and disease-specific mortality. This study aimed to investigate the…
View details →Park JE · 2026 · Korean journal of community nutrition
Objectives This study aimed to evaluate the relationship between oxidative balance score (OBS), a metric indicating an individual's oxidative balance status, and the number of teeth in a sample of Korean adults. Methods This…
View details →Hacıvelioğlu D, Turan Tercan A, Tuna Oran N · 2026 · BMC public health
This study examined xenophobia and empathic tendency among 724 midwifery students from different regions of Turkey. Data were collected online using the Student Information Form, the Empathic Tendency Scale, and the Xenophobia Scale, and…
View details →Skowron AT, Childers K, Rose CM et al. · 2026 · The Prostate
Purpose Germline genetic testing in patients with advanced prostate cancer (PCa) is underutilized and hypothesized to be impacted by socioeconomic and demographic factors. This single institution, retrospective study assessed the…
View details →Pisanu C, Squassina A, Perera-Bel J et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Treatment-resistant depression (TRD) is a major clinical challenge in the management of major depressive disorder (MDD). While pharmacogenetics has been suggested to be clinically useful in guiding…
View details →Madsen TE, Raker CA, Pavlovic JM et al. · 2026 · Neurology
Background and objectives Migraine is a known risk factor for stroke in women of reproductive age, although its relationship with stroke among postmenopausal women remains unclear. We assessed the association between migraine history and…
View details →Özen GY, Özen AK, Bilge NH · 2026 · Diagnostics (Basel, Switzerland)
Background: The anatomical position of the hyoid bone and the morphological characteristics of the soft palate play a key role in upper airway patency, craniofacial balance, and the coordination of functional structures. These features may…
View details →Clarke G, Shuweihdi F, Relton SD et al. · 2026 · The British journal of general practice : the journal of the Royal College of General Practitioners
Background Primary palliative care is symptom support and care for people with life-limiting illnesses incorporated within standard primary care. Early identification of needs is best practice. There is limited research concerning…
View details →Hallab A · 2026 · Thyroid research
Thyroid hormones modulate brain structures during neurogenesis and impact cognition and emotions during the lifetime. Hypothyroidism is commonly associated with lower gray matter volume. Fewer studies, however, highlighted significant…
View details →Ojo EO, Xie R, Ng BP et al. · 2026 · Research in gerontological nursing
Purpose The current study aimed to examine the association between cognitive function, fear of falling, and physical activity and assess the moderating effect of physical activity on the association between cognitive function and fear of…
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