11,412 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Lu J, Ahmad A, Chomont N et al. · 2026 · Frontiers in immunology
Due to persistent immune dysfunction, People with HIV (PWH) are at increased risk of more severe infections with SARS-CoV-2 and hospitalizations. In several countries, they were listed as a priority group for receiving anti-SARS-CoV-2…
View details →Kanamaru K, Sakai A, Kobayashi T et al. · 2026 · Clinical journal of gastroenterology
We present a rare case of autoimmune pancreatitis (AIP) confined exclusively to the subepithelial layer in the main pancreatic duct (MPD) without associated pancreatic enlargement or mass formation. A 73-year-old man presented with…
View details →Metwally NKA, de Boer F, Vreeken J et al. · 2025 · Scientific reports
This study compared three multiplex immunoassay platforms, Meso Scale Discovery (MSD), NULISA, and Olink, for detecting protein markers in stratum corneum tape strips, a non-invasive sampling method challenged by low protein yield. We…
View details →Karlina Y, Rizaldy D, Riani C et al. · 2026 · Iranian journal of microbiology
Background and objectives Enzymes are protein biomolecules that act as catalysts, including cellulase and β-glucosidase with extensive applications. Thus, this work aimed to contrast the activity of both enzymes from tempeh fermented by…
View details →Blach A, Kiss S, Fontaine A et al. · 2026 · Case reports in obstetrics and gynecology
Background and aims Anti-NMDAR encephalitis is a severe autoimmune encephalitis that is frequently associated with ovarian teratomas, whereas infectious triggers remain incompletely understood. We report a case of ovarian…
View details →Yang J, Zhu D, Liu R et al. · 2026 · Bioresource technology
Partial nitritation (PN) underpins two-stage anaerobic ammonium oxidation-based nitrogen removal, but biomass management in sidestream PN reactors remains largely empirical. This study tested three PN sequencing batch reactors maintained…
View details →Ashraf A, Shamel M, Massieh C et al. · 2026 · BMC oral health
Background Energy drinks are acidic beverages with recognized erosive potential, but their effect on enamel characteristics relevant to orthodontic bonding remains incompletely described. This in vitro study evaluated the effect of…
View details →Ganji SK, Talari K, Maloth RK et al. · 2026 · Rapid communications in mass spectrometry : RCM
Rationale Nitrite anion is among the highly reactive anions and converts the secondary amines to their corresponding carcinogenic N-nitroso metabolites in the human body. Nitrite ion is highly abundant in natural waters and enters the body…
View details →Niu J, Huang W, Zou J · 2026 · Clinical neurology and neurosurgery
Purpose To compare rupture-related signals captured by automatically extracted computed tomography angiography (CTA) morphologic features and threshold-based computed tomography perfusion (CTP) metrics in large unruptured intracranial…
View details →Xie B, Rui Y · 2026 · Plants (Basel, Switzerland)
Nanotechnology has attracted increasing attention in agricultural and environmental research, but the biological effects and potential risks of nanoparticles based on non-essential elements remain insufficiently understood. This study…
View details →Destro JM, Reis BO, Chrisostomo DA et al. · 2026 · Journal of functional biomaterials
This study aimed to evaluate the effects of experimental bioactive glass solutions on dentinal fluid flow and hydraulic conductance in vitro. Dentin blocks of 50 bovine incisors were divided into 5 groups according to the desensitizing…
View details →Xu Z, Su S, Xu Z et al. · 2026 · Frontiers in psychology
The Drive for Muscularity Attitudes Questionnaire (DMAQ) is a brief tool for assessing muscularity-related attitudes. This study translated the DMAQ into Chinese and evaluated its reliability and validity separately in males and females. A…
View details →Koyuncu Z, Evcil FY, Kilimci ÖS et al. · 2026 · BMC psychiatry
Objective This study investigated whether current comorbid psychiatric symptoms were involved in statistical indirect associations between childhood attention-deficit/hyperactivity disorder (ADHD) symptoms (CAS) and functional impairment…
View details →Gessler KB, Rescaroli J, Pires SM et al. · 2026 · Neurotoxicity research
Atorvastatin is a widely prescribed statin used for its cholesterol-lowering effects; however, it also exerts known pleiotropic effects, including antioxidant and anti-inflammatory properties. Atorvastatin´s impact on mitochondrial…
View details →Tuo Y, Yang S, Dai X et al. · 2026 · Journal of ethnopharmacology
Ethnopharmacological relevance Syringa oblata Lindl. emits a variety of biogenic volatile organic compounds (BVOCs) during full bloom, which forms the key chemical basis for its characteristic floral scent. Species of the genus Syringa…
View details →Zhen B, Yang X, Yao B · 2026 · Scandinavian journal of psychology
Child abuse has been significantly associated with children's mobile phone dependence (MPD), particularly in left-behind children (LBC). However, whether distinct forms of child abuse (physical and emotional) are associated with MPD in LBC…
View details →Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
View details →Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
View details →Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports
Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…
View details →Wei X, Xue M, Fan B et al. · 2026 · BMC pulmonary medicine
Background Long-term changes in lung function in children with symptom control asthma are rare. To assess the trajectory of pulmonary function in children and analyze the influence factors. Methods The effects of gender, age, Body Mass…
View details →Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology
Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…
View details →Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)
Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…
View details →Uğurlu İ · 2026 · Journal of clinical laboratory analysis
Background Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. Methods In this case-control…
View details →Qian MY, He LY, Lan P et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
This study aimed to identify predictors of outcomes and evaluate the therapeutic impact of surgical intervention in CM patients, with a specific focus on the growing HIV-negative population in East Asia. We conducted a single-center…
View details →Li L, Wang C, Ji Y et al. · 2026 · Behavioral sciences (Basel, Switzerland)
Previous research suggests receiving a concurrent auditory version of text during reading, i.e., reading-while-listening, improves eye-movement behavior in less skilled readers, while disrupting skilled reading. We extended this approach…
View details →Seiser M, Deininger C, Fierlbeck J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose External fixators are essential for the surgical management of long-bone fractures, particularly in resource-limited settings where access to commercial systems is often restricted by cost and logistics. This study aimed to develop…
View details →Batool SM, Lee H, Muralidharan K et al. · 2026 · Cancers
Characterizing the m6A epigenetic landscape is essential for understanding glioma biology, yet transcriptome-wide mapping of these modifications at isoform resolution across specific tumor subtypes has remained limited. Conventional…
View details →Chen Y, Gao L, Zheng Z et al. · 2026 · Scientific reports
Preoperative decision-making regarding extended pelvic lymph node dissection (ePLND) in prostate cancer remains challenging. Existing nodal-risk prediction tools are mainly based on clinicopathologic variables and may show suboptimal…
View details →Alghonemy WY, Ahmed NM, Abou Samra AA et al. · 2026 · Journal of oral biology and craniofacial research
Objective To evaluate the regenerative effects of platelet-rich plasma (PRP) combined with 3% low-molecular-weight hyaluronic acid (HA) gel in treating ligature-induced periodontitis in rats. Methods •40 male albino rats divided into 5…
View details →Selim AAMA · 2026 · Natural product research
Three hydrazone chromones 3a-c ( 3a, b in trans isomer while 3c was a mixture) and three hydrazone furanochromones 7a-c ( 7a in trans while 7b, c in cis ) carrying carboxylic acid or its bioisostere sulphonamide group were synthesised.…
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