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Browse the failure-mode index

11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Investigating the effect of probiotics on seizure-related symptoms in children with medication-resistant epilepsy: a randomized clinical trial.

Mohammadi M, Zahiroddin H, Mohammadi MS et al. · 2026 · Clinical neurology and neurosurgery

Introduction Antiseizure Medications (ASMs) can be beneficial for many patients with epilepsy; however, some individuals with medication-resistant epilepsy (MRE) may not experience effective seizure control. Although effective alternative…

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Negative / Null Result ReportMedicine

Unmasking the Relationship Between Cyber Dating Abuse and Fear of Intimacy: Insights From a Cross-Sectional Study of Undergraduate Students.

Büyüktopaç Çakici H, Çiçek Gümüş E, Dişli E et al. · 2026 · Journal of interpersonal violence

The increasing digitalization of the world has led to a rise in cyber dating abuse among undergraduate students, who are transitioning into young adulthood and will be part of the future workforce. Additionally, identifying the…

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Negative / Null Result ReportMedicine

The Relationship Between Biological Age and Emotional Intelligence in Young Swimmers.

Badzińska J, Żegleń M, Słowik J et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council

Objectives Emotional intelligence is crucial for young athletes, affecting their psychosocial well-being and performance. Biological development, which includes physiological changes, is also important for athletes, affecting their…

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Negative / Null Result ReportMedicine

How Corruption Influences Population Health.

Kyriopoulos I, Minos D, Vandoros S et al. · 2026 · The Milbank quarterly

Policy Points This study examines the link between corruption and mortality. We find that corruption is associated with higher mortality, particularly in low-income countries. It is also linked to lower government revenue and distorted…

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Negative / Null Result ReportMedicine

Radiation Exposure and Local Diagnostic Reference Levels During Endovascular Treatment of Cerebral Arteriovenous Malformations and Dural Arteriovenous Fistulas.

Sowa MS, Sowa J, Budzanowski M · 2026 · Biomedicines

Background/Objectives: Endovascular treatment of cerebral arteriovenous malformations (AVMs) and arteriovenous fistulas (AVFs) is associated with substantial radiation exposure due to procedural complexity and repeated angiographic…

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Negative / Null Result ReportMedicine

Associations Between Complementary Feeding Approach, Dietary Intake, and Growth: A Secondary Analysis of the Maternal and Infant Nutrition Trial.

Matzeller KL, Hernandez ML, Glime GNE et al. · 2026 · Journal of the Academy of Nutrition and Dietetics

Background Minimal research has assessed the adequacy of baby-led weaning (BLW) as a complementary feeding (CF) approach in infant nutrient intake and growth. Objective This study assesses growth between infants following BLW and…

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Negative / Null Result ReportOpen accessMedicine

Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia in very preterm infants: a prospective randomized controlled trial.

Wang B, Xu S, Li Z et al. · 2026 · Frontiers in pediatrics

Background To investigate the clinical efficacy and safety of inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia (BPD) in very preterm infants. Methods From October 2024 to November 2025,…

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Negative / Null Result ReportOpen accessMedicine

Exploring how weight stigma relates to psychological distress, physical activity, and eating behaviors over time: a longitudinal study among young adults in Hong Kong.

Fung XCC, Siu AMH, Ye J et al. · 2026 · Journal of eating disorders

Background Many researchers have expressed concerns that weight stigma may cause adverse health effects and worsen weight issues in a vicious cycle. However, empirical evidence evaluating this cycle is scarce, especially among Eastern…

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Negative / Null Result ReportOpen accessMedicine

The effect of moral distress experienced by intensive care nurses on end-of-life care attitudes and care behaviours: a single-centre cross-sectional and correlational study.

Özyürek P, Kılıç İ, Akarsu A et al. · 2026 · BMC nursing

OBJECTIVES: This study aimed to evaluate the effect of moral distress experienced by intensive care nurses on their attitudes toward end-of-life care and their care behaviors. METHODS: This cross-sectional and correlational study was…

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Negative / Null Result ReportMedicine

Examining the relationship between attachment styles, stress coping styles, and psychological resilience levels in adults seeking treatment for alcohol and substance use disorders.

Duran S, Demirci HT · 2025 · Journal of ethnicity in substance abuse

This relational survey study aims to examine the relationship between attachment styles, coping styles, and psychological resilience levels in adults seeking treatment for alcohol and substance use disorders. The study was conducted with…

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Negative / Null Result ReportOpen accessMedicine

Patterns in meperidine distribution and associations with income and obesity in the USA and Puerto Rico between 2019 and 2023: a retrospective study.

Gonzalez B, Healy LG, Harrison LR et al. · 2026 · BMJ open

Objectives Meperidine, once viewed as relatively safe, is now discouraged in clinical settings due to its associated risks. Previous studies have identified a significant decrease in meperidine distribution across the USA from 2000 to…

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Negative / Null Result ReportOpen accessMedicine

Modeling Factors Affecting Physicians' Acceptance of E-Prescriptions Using Structural Equation Modeling-Partial Least Squares Analysis: A Cross-Sectional Study.

Zahiri M, Yazdani A, Honarvar B et al. · 2026 · Health science reports

Background and aims The acceptance of technology is a critical factor influencing the success of health information systems. This study aimed to investigate the key factors affecting physicians' acceptance of electronic prescription…

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Negative / Null Result ReportMedicine

Impact of cone-beam computed tomography image quality on artificial intelligence-driven three-dimensional tooth segmentation and evaluation of external apical root resorption.

Senén-Carramolino R, Navarro-Fraile E, Dehesa-Santos A et al. · 2026 · The Angle orthodontist

Objectives To assess the reliability of the diagnostic method using Diagnocat artificial intelligence (AI)-generated standard tessellation language (STL) files and Geomagic Wrap software and to evaluate whether cone-beam computed…

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Negative / Null Result ReportMedicine

Phacoemulsification combined with bent ab interno needle goniectomy versus high-frequency deep sclerotomy: a comparative study of surgical outcomes in open-angle glaucoma.

Yayla U, Orenc P · 2026 · BMC ophthalmology

Background This study aims to compare intraocular pressure (IOP) reduction, surgical success, antiglaucoma medication (AGM) usage, complication profiles, and structural and functional outcomes between phacoemulsification combined with bent…

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Negative / Null Result ReportMedicine

An effective strategy for rare microdissection testicular sperm involves utilizing a micro-cryopreservation technique combined with laser-assisted selection of immotile sperm after thawing.

Lin R, Wang C, Xu K et al. · 2026 · Cryobiology

The challenge with spermatozoa retrieval in non-obstructive azoospermia (NOA) patients is that testicular spermatozoa are frequently immotile and exceedingly scarce. The cryopreservation of these limited spermatozoa and the subsequent…

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Negative / Null Result ReportMedicine

Cable versus cerclage wire in weber tension band fixation for transverse olecranon fractures: a biomechanical study in a synthetic ulna model.

Eyceyurt RS, Suer O, Uzakgider M et al. · 2026 · Scientific reports

Stable fixation of displaced simple transverse olecranon fractures is required to maintain reduction under triceps traction and enable early elbow motion. Although Weber tension band fixation is widely used, the biomechanical influence of…

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