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Browse the failure-mode index

11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Asthma in Active Military Aircrew: Long-term Health and Flight Performance.

Angel O, Rittblat M, Freund O et al. · 2026 · The Israel Medical Association journal : IMAJ

Background Asthma poses unique challenges in aviation medicine. While strict criteria typically dictate waiver approvals in military aviators with asthma, the Israeli Air Force (IAF) applies a more individualized approach. Still, evidence…

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Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

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Negative / Null Result ReportMedicine

Biomechanical assessment of intraocular lens stability and position based on suture and inlet variations in the Canabrava double-flanged technique.

Suh YK, Choi S, Yoon CK et al. · 2026 · Journal of cataract and refractive surgery

Purpose To evaluate how variations in suture type, suture length, and scleral outlet angle affect intraocular lens (IOL) positioning and fixation stability in the Canabrava technique, given ongoing concerns such as iris chafing and the…

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Negative / Null Result ReportMedicine

Differences in Cyclotorsion Compensation Between Low, Medium, and Large Angles in Myopic PRK: Visual and Refractive Results.

Ben Ephraim Noyman D, Safir M, Sommer A et al. · 2026 · Journal of refractive surgery (Thorofare, N.J. : 1995)

Purpose To evaluate the differences in myopic photorefractive keratectomy (PRK) outcomes between small, medium, and large cyclorotational angle degrees. Methods This retrospective comparative study was conducted at Care Vision Laser…

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Negative / Null Result ReportMedicine

Accuracy of Continuous Glucose Monitoring in Adults With Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass Surgery Under Stable and Dynamic Glucose Conditions.

Lizoain A, Vettoretti M, Ferreira A et al. · 2026 · Diabetes care

Objective Although continuous glucose monitors (CGMs) are increasingly used to detect and manage postbariatric hypoglycemia (PBH) and associated glucose variability, data on their accuracy in this population remain scarce. Research design…

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Negative / Null Result ReportMedicine

[Survey on the establishment of smoking areas in city halls in National Association of Directors of Health Departments of Designated Cities, West Block Conference].

Hamada M, Miyamura K, Kasamatsu M et al. · 2026 · [Nihon koshu eisei zasshi] Japanese journal of public health

Objectives In Tokyo, preventing passive smoking progressed during the 32nd Olympic Games. However, smoking areas remain in many local city halls, and tobacco product companies donate smoking areas in front of stations and near parks. A…

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Negative / Null Result ReportOpen accessMedicine

Relationships Among Cognitive Distortions, Forgiveness of Others, and Self-Forgiveness in Psychiatric Outpatients with Depressive Disorders: A Cross-Sectional Study.

Saklamaz S, Akpınar H · 2026 · Healthcare (Basel, Switzerland)

Background : Depression is associated with cognitive, emotional, and interpersonal difficulties that may influence forgiveness-related processes. This study aimed to examine the relationships among cognitive distortions, forgiveness of…

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Negative / Null Result ReportMedicine

An examination of core beliefs in generalized anxiety disorder.

Doust AE, Trenoska Basile V, McDonald S et al. · 2026 · The British journal of clinical psychology

Objective Generalised anxiety disorder (GAD) is characterised by uncontrollable worries. Cognitive behaviour therapy (CBT) is an effective treatment for GAD; however, manualised treatments rarely include interventions to target core…

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Negative / Null Result ReportMedicine

Myocardial expression of <i>ADGRL4</i> and <i>AQP7</i> is related to regression of left ventricular hypertrophy after aortic valve replacement in a sex-dependent manner.

Halldórsson KB, Karagianni K, Leite-Moreira AF et al. · 2026 · American journal of physiology. Heart and circulatory physiology

Aortic stenosis (AS) may lead to left ventricular (LV) hypertrophy (LVH). After aortic valve replacement (AVR), LVH often does not regress fully. This has been associated with a worse prognosis. This study aimed at comparing LVH regression…

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Negative / Null Result ReportOpen accessMedicine

Migraine as an occupational health risk among nurses in Qassim region, Saudi Arabia: a multicenter study of risk perceptions and associated factors.

Qalawa SAA, Elbqry MG, Elmansy FM et al. · 2026 · Frontiers in public health

Background Migraine is a common neurological disorder and an emerging occupational health risk among nurses due to demanding workloads, shift work, workplace stress, and prolonged screen exposure. Understanding nurses' risk perceptions of…

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Negative / Null Result ReportOpen accessMedicine

The Relationship between Perceived Food Environment and Glycemic Control Among Malaysian Diabetic Patients.

Berahim AS, Rohana AJ, Yaacob NM et al. · 2026 · International journal of preventive medicine

Background The perceptions of diabetic patients on their food environment influence their dietary choices and would impact glycemic control. The main aim of this study was to determine any relationship between perceived food environment…

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Negative / Null Result ReportMedicine

Interspecific patterns of variation in dental growth increments of crocodilians.

Hogg R · 2026 · Developmental dynamics : an official publication of the American Association of Anatomists

Background Multiple studies have supported the hypothesis that incremental growth lines in crocodilian dentin are analogous with circadian von Ebner's lines in mammals; however, variation in these growth lines has been largely unstudied.…

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Negative / Null Result ReportMedicine

A 10-Year Retrospective Cohort Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at the Royal Brisbane and Women's Hospital.

Pagliaro T, Butler G, Godbolt A et al. · 2026 · The Australasian journal of dermatology

Background/objectives The Royal Brisbane & Women's Hospital (RBWH) in Queensland, Australia provides definitive care for all diagnosed adult patients with SJS/TEN within its catchment. In this retrospective cohort study, we identified all…

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Negative / Null Result ReportOpen accessMedicine

A scoping review of mystical-type experiences and mood symptom outcomes in psychedelic therapy clinical trials: comparing life-threatening disease and depressive populations.

Deutsch A, Contreras LE, Kratina S et al. · 2026 · Therapeutic advances in psychopharmacology

Background Psychedelic therapies are gaining attention as tools to alleviate anxiety and depression across various clinical populations. However, the mechanisms behind psychedelics' therapeutic efficacy and the potential differences in how…

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