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Browse the failure-mode index

11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

The Role of the Tear Film in Refraction: Quantitative Evaluation Before and After Rexon-Eye Therapy.

Stankovičová V, Nováček VL, Rozsíval P · 2026 · Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti

Aim The aim of this study was to assess the effect of Rexon-Eye therapy, based on quantum molecular resonance (QMR) technology, optical parameters, tear film stability, and patients' subjective symptoms. Material and methods A total of 30…

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Negative / Null Result ReportMedicine

Sexual function in perimenopausal women treated with relugolix and add back therapy for uterine fibroids: an observational study.

Mancarella M, Novara L, Carignano S et al. · 2026 · The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception

Objectives Uterine leiomyomas may cause disorders such as bleeding and bulky symptoms impacting on quality of life; a recent therapeutic option is relugolix, a GnRH antagonist effective in controlling bleeding and reducing the size of…

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Negative / Null Result ReportOpen accessMedicine

Corneal Biomechanics Before and After Descemet Membrane Endothelial Keratoplasty in Patients with Fuchs Endothelial Corneal Dystrophy.

Reinprayoon U, Yaisawang S, Israsena N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)

Purpose Descemet Membrane Endothelial Keratoplasty (DMEK) is a surgical intervention for restoring endothelial function in Fuchs endothelial corneal dystrophy (FECD). However, changes in corneal biomechanical properties assessed using…

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Negative / Null Result ReportMedicine

Effects of an 8-Week Time-Restricted Eating and Walking Exercise on Regional Fat Distribution and Lean Mass in Women with Hidden Obesity: A Randomized Controlled Trial.

Chen S, Kortas J, Ren Y et al. · 2026 · Healthcare (Basel, Switzerland)

Objectives : Explore and compare the effects of 8-week time-restricted eating (TRE), walking exercise, and their combination on fat and lean muscle distribution in female college students with hidden obesity. Methods : A total of 68…

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Negative / Null Result ReportMedicine

The effect of harmonica-based breathing and airway clearance exercises on pulmonary function in children with cystic fibrosis: A randomized controlled trial.

Tavasoli H, Rajabi MM, Sadat Hoseini AS · 2026 · Journal of pediatric nursing

Purpose To determine the effect of harmonica-based breathing and airway clearance exercises on pulmonary function in children with cystic fibrosis (CF). Methods This randomized controlled trial included 70 children with CF aged 8-18 years.…

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Negative / Null Result ReportMedicine

Effect of Thermal Processing on the Nutritional Composition and Bioactive Compounds of 'Largueta' Almonds (<i>Prunus dulcis</i>).

Fernández-León MF, Flórez Acosta LR, Fernández-León AM · 2026 · Foods (Basel, Switzerland)

Almond ( Prunus dulcis ) is a highly nutritious nut, rich in unsaturated fatty acids, fibre, and bioactive compounds such as tocopherols, phenolic compounds, and carotenoids. Processing methods commonly applied in the almond industry,…

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Negative / Null Result ReportMedicine

Evaluation of the first edition of the 'Spirituality in medicine' programme implemented for medical students at the Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Poland. Pre- and post-test research.

Fopka-Kowalczyk M, Krajnik M · 2026 · BMC medical education

Background This article presents an evaluation of the first obligatory programme on 'Spirituality in Medicine' for medical students in Poland, implemented at the Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in…

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Negative / Null Result ReportMedicine

Hepatic inflammation after exposure to a mixture of low-dose arsenic and cadmium in a murine model of fatty liver disease.

Subramaniam NK, Gagnon N, Guilbert C et al. · 2026 · Toxicological sciences : an official journal of the Society of Toxicology

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health burden and major contributor to chronic liver disease. Evidence suggests arsenic (As) and/or cadmium (Cd) exposure may influence MASLD development,…

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Negative / Null Result ReportMedicine

Test-Retest reliability of performance, knee functionality and movement quality biomechanics in agility T-test using markerless motion capture.

Wen Z, Claeys K, García JG et al. · 2026 · Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology

The purpose of this study was to assess reliability of performance, knee functionality and movement quality parameters in agility T-test using markerless motion capture. Seventeen healthy participants performed two sessions of agility…

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Negative / Null Result ReportMedicine

Heterogeneous rebound patterns of foodborne diseases after COVID-19 non-pharmaceutical interventions, South Korea, 2005-2024.

Kim S, Chun BC · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Objectives To characterize pathogen-specific patterns of foodborne diseases across the full COVID-19 pandemic period, including post-non-pharmaceutical intervention (NPI) relaxation through 2024. Methods We conducted interrupted time…

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Negative / Null Result ReportMedicine

Effects of a Self-Management Program for Temporomandibular Myalgia in Patients With Fibromyalgia: A Single-Arm Study.

Ferrández-Gómez JE, Baño-Alcaraz A, Gacto-Sanchez M · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses

Purpose Myogenic temporomandibular disorder frequently co-occurs with fibromyalgia and is associated with pain, disability, and maladaptive pain cognitions. This study evaluated the short- and long-term effects of an online Pain…

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Negative / Null Result ReportMedicine

Angiotensin (1-7) exaggerates albuminuria and nephrin gene expression but does not modulate renal function-specific microRNAs expressions in kidneys of db/db mice.

Malatiali S, Khamisi S, Kilarkaje N · 2026 · Acta diabetologica

Aim This study investigated the effects of angiotensin (1-7) on diabetes-induced renal injury and renal miRNA levels in obese type 2 diabetic db/db mice. Methods Treatment with angiotensin (1-7) (500 μg/kg; i.p.) was started when the mice…

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Negative / Null Result ReportMedicine

Effect of different positions of lumbar traction on pain, function, and range of motion in adults with non-specific low back pain: a randomized clinical trial.

Mahmoud WS, Alhowimel A, Almotery A et al. · 2026 · Scientific reports

Non-specific low back pain (NSLBP) represents about 80-95% of all LBP cases, yet the optimal lumbar traction position for effective treatment remains debated. To investigate the effect of different positions during lumbar traction on pain,…

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Negative / Null Result ReportMedicine

Thermographic response to acute muscle fatigue and delayed onset soreness (DOMS) following a protocol until exhaustion with concentric exercises in the triceps suralis.

Cabizosu A, Zoffoli A, Mevi R et al. · 2026 · Physiological measurement

Objective. Infrared thermography is projected as an innovative and very promising tool for the observation of muscle response to fatigue. The aim of this study was to observe the skin temperature (Tsk) by thermography about acute muscle…

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