11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Gong C, Li W, Liu S et al. · 2026 · Journal of experimental botany
Iron (Fe) and zinc (Zn) deficiencies severely threaten global human health. Thus, rice biofortification to enhance intrinsic Fe and Zn levels in grains represents an effective strategy to alleviate human Fe and Zn deficiencies. Several…
View details →Anatolitou A, Mavrogenis AF, Sideri KI et al. · 2026 · Polish journal of veterinary sciences
Cartilage defects have limited regenerative potential and remain a significant clinical challenge. Mesenchymal stem cell (MSC) therapy offers promise in tissue engineering, yet monitoringpost-implantation responses remains difficult.…
View details →Arslan K, Baş S, Temizel M et al. · 2026 · Nutricion hospitalaria
Objective this study aimed to assess and compare nutritional status in patients undergoing sleeve gastrectomy using the Naples Prognostic Score, PNI, and CONUT indices, with the objective of facilitating early identification of…
View details →He M, Huang Z, Pooe OJ et al. · 2026 · Ecotoxicology (London, England)
Most of eco-toxicity studies of Bacillus thuringiensis (Bt) proteins on terrestrial organism were conducted with Bt-crops straw or leaves on earthworm Eisenia fetida. Nevertheless, extra nutrition from straw or leaves degradation affected…
View details →Lin CH, Liu MY · 2026 · Geriatric nursing (New York, N.Y.)
Objectives Frailty negatively impacts quality of life and increases pressure on healthcare systems. This study aimed to evaluate the effects of a nurse-led Frailty Prevention Care Management Program (FPCMP-Old Age), based on the Chronic…
View details →Pio-Soria A, Zahran D, Roldán-Ruiz A · 2025 · Healthcare (Basel, Switzerland)
Introduction Primary dysmenorrhea is one of the most prevalent gynecological disorders. It has been shown to negatively impact quality of life and overall wellbeing, as recent studies have associated stress and physical inactivity with…
View details →Ramli FF, Villa LM, Martens MAG et al. · 2026 · Scientific reports
Ebselen has been shown to induce a positive emotional processing bias and brain neurochemistry in healthy volunteers. However, little is known about its effects on resting-state functional connectivity (rs-FC) in depressed patients who…
View details →Sharma M, McCall WV, Rosenquist PB · 2026 · The journal of ECT
Objectives To examine the acute and longitudinal effects of repetitive transcranial magnetic stimulation (rTMS) on-autonomic nervous system measures (ANS)-heart rate variability (HRV) and pupillary light reflex (PLR)-in adults with major…
View details →Osmanova F, Bulbul A, Bas EK et al. · 2026 · BMC pediatrics
Background It is essential to assess not only the hematologic outcomes but also the immunologic and inflammatory consequences of RBC transfusion in preterm infants. Aims This study aimed to evaluate changes in serum cytokine levels…
View details →Högberg JH, Philips B, Stålheim J et al. · 2026 · Psychology and psychotherapy
Objectives Despite recognised cognitive deficits related to substance use, as well as high mortality and treatment attrition rates, metacognition has never been studied in patients with opioid use disorder (OUD) undergoing opioid…
View details →Vidal C, Prichett L, Yang A et al. · 2026 · The American journal of emergency medicine
Objective Youth suicide rates have increased over the last three decades, translating into an increase in related pediatric emergency department (ED) visit demands. However, these trends shifted during the pandemic. We describe demographic…
View details →Tounsi M, Aiouaz F, Acheche A et al. · 2026 · International journal of sports medicine
Abstract Integrating proprioceptive and neuromuscular exercises into the FIFA 11+ Kids program may enhance motor performance and postural stability in youth athletes. This study aimed to determine the effects of a 12-week combined FIFA 11+…
View details →Steinacker AC, Bischof L, Herchet D et al. · 2026 · BMC medical education
Background Weight-related stigma toward people living with obesity is widespread in healthcare settings and has been documented among students and professionals across health disciplines. Such stigma may negatively affect communication,…
View details →Hari S, Kumamoto M, Suzuki M et al. · 2026 · Sangyo eiseigaku zasshi = Journal of occupational health
Objectives This single-arm before-after study examined short-term changes in body weight following a 28-day self-selected, type-tailored lifestyle modification program implemented before workplace health checkups. Participants…
View details →Moeckel C, Anderson R, Krnajic L et al. · 2026 · Pediatric dermatology
This study evaluated the impact of an elementary school-based intervention that aimed to improve sun safety knowledge and behaviors among third- and fourth-grade students in Pennsylvania through an educational video, t-shirt design…
View details →Sinvani RT · 2026 · Journal of voice : official journal of the Voice Foundation
Child-directed speech (CDS) prosodic modifications are well-documented in infancy, but their persistence into middle childhood remains understudied. To address this gap, this study examined developmental changes in acoustic properties of…
View details →Peters F, Weghorst J, Paetzolt M et al. · 2026 · Ecology and evolution
Climate change is driving significant changes in alpine ecosystems, where temperature-sensitive plant communities are particularly vulnerable. As plants migrate to higher elevations, understanding the mechanisms behind these changes is…
View details →Wakhisi AS, Katsouyanni K, Evangelopoulos D et al. · 2026 · Public health
Objectives This study assessed the short-term respiratory health effects associated with recurrent fire incidents at Arnold's Field, a former landfill site in the London Borough of Havering, among residents living in close proximity. Study…
View details →Berry A, Watson M, Moore M et al. · 2026 · Epilepsy & behavior : E&B
Background and objectives Functional/dissociative seizures (FDS) are frequently treated with one-to-one therapeutic interventions. However, data describing patient-reported outcome measures (PROMs) following group-based therapy remain…
View details →Barberán-Bernardos L, Ariza-Gracia MA, Büchler P et al. · 2026 · Life (Basel, Switzerland)
This study aims to characterize diurnal changes in corneal geometry of the anterior and posterior cornea in healthy eyes using global and sector-based metrics, and to explore their associations with lifestyle-related factors. A prospective…
View details →Cheng CW, Fang WF, Yang YM et al. · 2026 · Immunopharmacology and immunotoxicology
Background Hydroxychloroquine (HCQ) is a commonly used immunomodulatory drug in various autoimmune diseases; however, its role in autoimmune thyroid diseases (AITDs) remains unclear. Objective This study aimed to evaluate the potential…
View details →Volpe G, Bonanata M, Peyla A et al. · 2026 · Ophthalmology and therapy
Introduction Intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is the standard of care for neovascular age-related macular degeneration (nAMD) and other retinal vascular diseases. However, transient post-injection…
View details →Genç E, Bilekyiğit Kurt C, Evrim Karadağ Saygi N et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Musculoskeletal abnormalities are common to mucopolysaccharidoses (MPS) and can negatively affect the patient's quality of life. Data on course of musculoskeletal findings of MPS type IVA and VI are very insufficient. This study…
View details →Martikainen A, Eloranta AM, Schwab U et al. · 2026 · Trials
Background Lifestyle interventions can reduce the risk of becoming an overweight adult and reduce the risk of health problems. The aim was to investigate the effects of obesity treatment on BMI-for-age, metabolic markers, and quality of…
View details →Asbi T, Mayer Y, Sarikov R et al. · 2026 · The Saudi dental journal
Maxillectomy produces extensive oral and maxillofacial defects that disrupt normal physiology and often require obturator prostheses for functional and aesthetic rehabilitation. Although these devices are routinely used, their influence on…
View details →Stoll PD, Thol F, Spuck N et al. · 2026 · The Journal of craniofacial surgery
Introduction Orthognathic surgery is traditionally considered painful, often prompting opioid use. In the context of rising opioid-related harm, this study assessed postoperative pain levels, factors influencing analgesic requirements, and…
View details →Lafitte E, Sfumato P, Walz J et al. · 2026 · World journal of urology
Introduction Preoperative anemia (PA) and red blood cell transfusion (RBT) are associated with decreased survival in several cancers. In muscle-invasive bladder cancer (MIBC), anemia is frequent and may be worsened by neoadjuvant…
View details →Jones A, Johnco C, Beyersmann E et al. · 2026 · Child psychiatry and human development
Poor reading ability is associated with internalising symptoms in children; however, little research has been done with adolescents. The current study used self- and parent-report data from two cohorts of the Longitudinal Study of…
View details →Majidi S, Rouhi A · 2026 · BMC primary care
Background Obsessive-Compulsive Disorder (OCD) is one of the psychiatric disorders which characterized by unwanted thoughts (obsessions) and repetitive behaviors (compulsions). Mental health problems can affect job performance of…
View details →Yaemrattanakul W, Manachamni K, Ruangrattanapong J et al. · 2026 · BMC psychology
Background Healthcare undergraduate students often face high cognitive and emotional stress, negatively affecting their working memory and well-being. Mindfulness-based practices, such as sitting meditation and body scan, are proposed to…
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