11,310 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Mukherjee, Watson, Wallbanks et al. · 2026 · Cureus
Obesity as the primary cause of acute hypercapnic respiratory failure (AHRF) receiving acute non-invasive ventilation (NIV) has doubled within a decade. We analysed the primary diagnoses for receiving home mechanical ventilation (HMV) upon…
View details →Scanlin, Salazar · 2026 · Veterinary anaesthesia and analgesia
To compare postoperative analgesic efficacy between ropivacaine and liposomal bupivacaine when used for an erector spinae plane (ESP) block as part of analgesic management for hemilaminectomy surgery caudal to the eleventh thoracic…
View details →Gayraud, Lequy, Hucteau et al. · 2026 · Ophthalmology science
Age-related macular degeneration (AMD) and cataracts are part of the leading causes of blindness globally, with oxidative stress being a key factor in their development. Air pollution, known to exacerbate oxidative stress, may contribute…
View details →Ankmnal Veeranna, Chapman · 2026 · American journal of audiology
The purpose of the present study was to determine whether standard and high-frequency transducers influence test scores on clinically used speech-in-noise (SIN) assessments, such as the Word-In-Noise (WIN) and QuickSIN tests. Sixteen…
View details →Wu, Zhang, Wang et al. · 2026 · Frontiers in ophthalmology
To assess central corneal thickness (CCT), as well as the density and morphology of corneal endothelial cells (ECD) in myopic eyes. A total of 400 patients scheduled for myopic refractive surgery were consecutively enrolled in this study.…
View details →Sai-Ut, Indriani, Srisakultiew et al. · 2026 · Food science of animal resources
Meat tenderness is key to consumer acceptance but is challenged by goat meat's leanness and high connective tissue content. A promising solution is the in-pack combination of ultrasonication (US) and sous-vide (SV) technologies to enhance…
View details →Li, Peng, Song et al. · 2026 · Poultry science
The development and utilization of unconventional feed such as sprayed corn bran (SCB) have effectively alleviated the shortage of feed raw materials, although its application in meat geese production has rarely been reported. Therefore,…
View details →Bao, Wu, Li et al. · 2026 · BMC cardiovascular disorders
Atrial fibrillation (AF) with coronary artery disease (CAD) requiring percutaneous coronary intervention (PCI) - including both acute and chronic presentations - is common, yet the optimal antithrombotic regimen remains unclear. This study…
View details →Mukhopadhyay, Modgekar, Yang-Hood et al. · 2026 · Scientific reports
Quantal synaptic transmission in vestibular endorgans is glutamatergic. Here, we investigated the vestibular phenotype of deaf Vglut3 -/- (Slc17a8 -/- ) mice from the cellular to behavioral levels. In Vglut3 -/- mice, quantal synaptic…
View details →Miyazaki, Ishigo, Yamada et al. · 2026 · Journal of pharmaceutical health care and sciences
Candidemia has high mortality and requires early antifungal stewardship (AFS). Management by non-infectious disease specialists has been associated with worse outcomes, particularly in small- and medium-sized hospitals where infectious…
View details →Wiseman R, Watt C · 2026 · PeerJ
Preregistration is commonly seen as an effective way of reducing questionable research practices within psychology. This procedure happens prior to data collection/analysis and usually involves either sending in a research plan to a study…
View details →Hansen-Lewis J, Marcus M · 2025 · American economic journal. Economic policy
Maritime shipping emits as much fine particulate matter as half of global road traffic. We are the first to measure the consequences of US maritime emissions standards on air quality, human health, racial exposure disparities, and…
View details →Schauer JM · 2023 · Multivariate behavioral research
A prominent approach to studying the replication crisis has been to conduct replications of several different scientific findings as part of the same research effort. The reported proportion of findings that these programs determined…
View details →Orhan B, Nauta M · 2026 · Death studies
Meaning Management Theory suggests that engaging with meaning-related resources helps individuals constructively regulate consciously experienced death anxiety. Consistent with that theory, we tested whether a single-session, online…
View details →Mitsuhara, Shimizu, Ebihara et al. · 2026 · Acute medicine & surgery
This study aimed to evaluate whether early enteral nutrition can be administered without increasing gastrointestinal complications in patients receiving mechanical circulatory support. This retrospective observational study was conducted…
View details →Pang, Hageman, Lou · 2026 · International journal of pharmaceutics
Tissue back pressure is an important indicator of tissue resistance during subcutaneous injection and is associated with injection performance and patient experience. Currently, assessments of tissue back pressure during injection are…
View details →Littlejohn, Zuckerman, Gargurevich et al. · 2026 · Journal of asthma and allergy
Determine if there is a difference in race, socioeconomic factors and baseline asthma severity at the time of biologic initiation and whether those characteristics are associated with response to therapy within 18 months of initiation.…
View details →Shen, Dai, Hu et al. · 2026 · Quantitative imaging in medicine and surgery
Inguinal lymph node (ILN) metastasis significantly affects prognosis and treatment strategies in patients with gynecological malignancies. Conventional ultrasound (US) provides morphological assessment but has limited sensitivity for…
View details →Nakamura N · 2026 · Annals of the ICRP
Radiation risks for cancer are classified into probabilistic effects because the induction of oncogenic mutations in a single epithelial cell is thought to be causally related to the process of carcinogenesis. However, two observations…
View details →Joshi, Scheuer, Chew et al. · 2026 · JACC. Heart failure
Heart transplantation (HT) from donation after circulatory death (DCD) donors has successfully expanded the donor pool with excellent short-term survival outcomes, but there is uncertainty regarding long-term outcomes. This study compared…
View details →Shi, Qu, Wang et al. · 2026 · Frontiers in microbiology
Human papillomavirus 33 (HPV33) is among the five most prevalent HPV genotypes in China and is commonly involved in co-infections. However, the synergistic effects of specific genotype combinations on cervical carcinogenesis remain…
View details →Sheikhzadeh, Sheikhhoseini, Piri et al. · 2026 · PeerJ
Many yoga poses involve supporting part or all of the body weight on the shoulder girdle and arms, which impose high loadings on the shoulder girdle. The present study aims to investigate the differences in electromyographic (EMG) activity…
View details →Iwamoto, Takagawa · 2026 · Scientific reports
Accurate modelling of tropical cyclones (TCs) is essential for reliable storm surge simulations, as TCs provide the primary external forcing. While deep learning models have demonstrated effectiveness in TC modelling, a challenge remains…
View details →Ding, Lou, Liang et al. · 2026 · Journal of animal science and biotechnology
Amuc_1100, the most abundant outer membrane protein of Akkermansia muciniphila, alleviates high-fat diet (HFD)-induced hepatic lipid accumulation and modulates gut microbiota in fish; however, its mechanism and mediators remain unknown.…
View details →Peng, Nik Othman, Zakaria et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
While the application of tuning fork Weber (TFW) test in adult is well-documented, its accuracy in the paediatric population remains uncertain although conductive hearing loss is frequently identified in children. Similarly, the…
View details →Sabatini, Molinero-Mourelle, Limones et al. · 2026 · The Journal of prosthetic dentistry
Whether the manufacturing protocol (build orientation and sintering schedule) of additively manufactured (AM) zirconia impacts the bond strength compared with subtractively manufactured (SM) zirconia remains unclear. The purpose of this in…
View details →Amate A, Lieberman M · 2026 · Harm reduction journal
Medetomidine has recently emerged in the illicit drug supply in the United States, and lateral flow immunoassay test strips are an inexpensive and easy-to-use field screening option for detecting this highly potent sedative. However, the…
View details →Li M · 2026 · Laboratory medicine
Introduction The use of virtual crossmatch for HLA antigen compatibility assessment before transplantation has become common practice in transplantation medicine. The accuracy of virtual crossmatch relies on accurate and complete donor HLA…
View details →Roy, Jahagirdar, Kumar et al. · 2026 · Journal of bodywork and movement therapies
Deteriorating physical performance with ageing increases the risk of falls, loss of independence, institutionalisation and mortality amongst elderly. Apart from multisystem body decline, poor quality sleep, being a common complaint amongst…
View details →Martiren, Llaguno-Rubio, Fiori-Chincaro et al. · 2026 · Journal of clinical and experimental dentistry
To evaluate the morphological characteristics of hypercementosis and its association with local factors using cone beam computed tomography (CBCT) in a population from Uruguay. This observational, cross-sectional, retrospective study…
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