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11,407 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Impact of central adiposity on the heart rate and calorie estimation accuracy of diverse smartwatches and the resulting subjective exercise experience.

Lertyongphati, Udomkhwamsuk, Amornrungrojanakul et al. · 2026 · Frontiers in sports and active living

In light of the growing global trend toward health awareness, wearable technologies like smartwatches have become essential for monitoring physiological indicators such as heart rate (HR). However, their utility faces two critical…

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Negative / Null Result ReportMedicine

Transcervical carotid artery stenting compared to transfemoral carotid artery stenting and carotid endarterectomy: perioperative and short-term results from a single center.

Jin, Ni, Huang et al. · 2026 · Frontiers in cardiovascular medicine

Carotid artery stenosis is a major cause of ischemic stroke. Various revascularization strategies exist, including Carotid Endarterectomy (CEA), Transfemoral Carotid Artery Stenting (TF-CAS), and Transcervical Carotid Artery Stenting…

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Negative / Null Result ReportMedicine

Accuracy of Visual Inspection of Thickened Liquids: Implications for Multidisciplinary Dysphagia Management and Clinical Nutrition.

Fong, Kwan · 2026 · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association

To evaluate the accuracy of visually estimating thickened liquid volume via video-observed conditions and to determine whether clinical experience or thickener composition influences judgement reliability. A cross-sectional online survey…

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Negative / Null Result ReportMedicine

The relationship between appetite hormones and body mass index in children with intoxication type metabolic diseases.

Koç, Konyalıgil, Özen Yeşil et al. · 2026 · Orphanet journal of rare diseases

The aim of this study is to comparatively examine the effects of appetite loss and insufficient energy intake, which trigger poor metabolic control parameters, on appetite hormones and body mass index in children with intoxication-type…

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Negative / Null Result ReportMedicine

The Effect of the Temporal Position of a Gap on Its Automatic Detection.

Omidvar, Campbell, Alain et al. · 2026 · The European journal of neuroscience

The presentation of a rarely occurring auditory stimulus that contains a silent interval (or gap) among a sequence of frequently occurring stimuli that do not contain a gap can elicit a negative-going event-related potential known as the…

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Negative / Null Result ReportMedicine

Prognosis of ER-positive, HER2-negative postmenopausal early breast cancer patients based on response to neoadjuvant endocrine therapy and multigene assay results: findings from the NEOS trial.

Iwata, Masuda, Yamamoto et al. · 2026 · Breast cancer (Tokyo, Japan)

We previously reported the 21-gene Oncotype DX® assay results from TransNEOS in patients enrolled in the phase 3 NEOS trial. However, the association between assay results and long-term prognosis has remained unclear. Of the 296…

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Negative / Null Result ReportMedicine

Clinically indicated versus routine replacement of peripheral intravenous cannulas in elderly patients: Secondary analysis of a multi-center randomized controlled trial in mainland China.

Jiang, Wang, Wei et al. · 2026 · Geriatric nursing (New York, N.Y.)

Peripheral Intravenous Cannulas (PIVCs) are extensively used for infusion therapy. Although current evidence suggests that adult patients may have PIVCs removed based on clinical indications, the indication in elderly patients remains…

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Negative / Null Result ReportMedicine

CT Perfusion Blood Flow Provides an Early Response Marker for Progression-free Survival in a Prospective Randomized Clinical Trial of Metastatic Renal Cell Carcinoma.

Ng, Chen, Wei et al. · 2026 · Technology in cancer research & treatment

IntroductionThere is currently no biomarker for progression-free survival (PFS) for patients undergoing treatment for metastatic renal cell carcinoma (RCC). The aim of our study was to evaluate computed tomography perfusion (CTp) blood…

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Negative / Null Result ReportMedicine

The Utility of Large Language Models to Assist With Emergency Triage Decisions Within Otolaryngology.

Hack, Attal, Steckbeck et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

To determine whether contemporary large language models can match clinician performance in evaluating the urgency of emergency otolaryngology referrals. Blinded cross-sectional diagnostic reasoning study. Simulated emergency referral…

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Negative / Null Result ReportMedicine

Relation between forearm flexor-pronator muscle elasticity and ulnar collateral ligament laxity of the elbow joint in high school pitchers with and without medial elbow tenderness: evaluation using shear wave elastography.

Tajika, Shitara, Hatori et al. · 2026 · JSES international

The forearm flexor-pronator muscle contributes to the dynamic stabilizer against valgus stress at the elbow during pitching motion. This study used shear wave ultrasonography to assess the relation between the elasticity of each forearm…

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Negative / Null Result ReportMedicine

Differences in gut microbiome of Hanwoo (Korean indigenous cattle) calves as driven by bovine rotavirus and bovine coronavirus infection.

Ku, Lee, Jung et al. · 2026 · Journal of animal science and technology

The gut microbiome of cattle suppresses pathogens and aids host immunity. However, the gut microbiome of newborn calves is still developing; therefore, diarrhea caused by pathogen infection is common. Rapid changes in the gut microbiome…

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Negative / Null Result ReportMedicine

External Validation of a Deep Learning-Based Artificial Intelligence System for Ultrasound Diagnosis of Thyroid Nodules: A Two-Center Retrospective Study.

Tang, Xu, Zhao et al. · 2026 · Journal of clinical ultrasound : JCU

To investigate the performance of an artificial intelligence (AI) diagnostic system for thyroid nodule sonography based on deep learning convolutional neural network (CNN). We retrospectively included 485 thyroid nodules with definite…

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Negative / Null Result ReportMedicine

Robotic vs. open liver resection after neoadjuvant therapy for hepatocellular carcinoma: a propensity score-matched analysis of short- and long-term outcomes.

Zhang, Li, Chen et al. · 2026 · Surgical endoscopy

Neoadjuvant therapy is recommended for hepatocellular carcinoma at advanced stages. It is unknown whether robotic liver resection (RLR) is superior to open liver resection (OLR) after neoadjuvant therapy. We analyzed consecutive RLR and…

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Negative / Null Result ReportMedicine

Association of ultra-processed foods (UPFs) with hypertriglyceridemic waist (HTGW) phenotype, oxidative stress, and inflammation in Iranian adults: a cross-sectional study.

Rostamian, Moabedi, Poursalehi et al. · 2026 · Food & function

In this study, we evaluated the association between UPFs with HTGW in relation to oxidative stress and inflammation in Iranian adults, as no previous study had assessed these altogether. This cross-sectional study consisted of a sample of…

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Negative / Null Result ReportMedicine

Predictors of Adenosine-Induced Sinus Pause Duration for Supraventricular Tachycardia in the Emergency Department: The Role of Body Mass Index and Symptom Duration.

Ozatak, Sonmez, Ozatak et al. · 2026 · The Journal of emergency medicine

Intravenous adenosine is the standard first-line therapy for stable supraventricular tachycardia (SVT). However, transient post-cardioversion sinus pauses frequently complicate its use, causing clinical anxiety. Patient-specific factors…

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Negative / Null Result ReportMedicine

Evaluation of physicochemical and antibacterial properties of an experimental adhesive resin containing casein phosphopeptide-amorphous calcium phosphate.

Balkaya, Göçer, Demirbuğa · 2026 · Odontology

This study aimed to evaluate the polymerization, contact angle, surface tension, antibacterial activity, and bonding properties of experimental adhesives modified with the addition of casein phosphopeptide-amorphous calcium phosphate…

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Negative / Null Result ReportMedicine

Comparative Evaluation of Bond Strength of Bioflx Crowns with Resinous and Nonresinous Luting Agents on Primary Teeth: An In Vitro Study.

Tasgaonkar, Rathi, Agrawal et al. · 2026 · International journal of clinical pediatric dentistry

Preserving primary teeth with crowns is vital in pediatric dentistry, especially for those compromised by dental caries, previous treatments, or malformations. To address the limitations of traditional esthetic crowns, Bioflx crowns have…

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