11,309 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ge, Wei, Qi et al. · 2026 · NPJ precision oncology
Effective predictive biomarkers for immunotherapy in breast cancer remain elusive, limiting precision treatment strategies. Although the biological significance of HER2‑low expression has gained increasing attention, its impact on…
View details →Aung, Shang, Zhu et al. · 2026 · Aesthetic plastic surgery
Pulse dye laser (PDL) and intense pulse light (IPL) have been applied in the early scar treatment to alleviate erythema, but no comparative analysis has been conducted to evaluate the performance of the two. This is a retrospective…
View details →Jiang, Wang, Wei et al. · 2026 · Geriatric nursing (New York, N.Y.)
Peripheral Intravenous Cannulas (PIVCs) are extensively used for infusion therapy. Although current evidence suggests that adult patients may have PIVCs removed based on clinical indications, the indication in elderly patients remains…
View details →Ng, Chen, Wei et al. · 2026 · Technology in cancer research & treatment
IntroductionThere is currently no biomarker for progression-free survival (PFS) for patients undergoing treatment for metastatic renal cell carcinoma (RCC). The aim of our study was to evaluate computed tomography perfusion (CTp) blood…
View details →Hack, Attal, Steckbeck et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
To determine whether contemporary large language models can match clinician performance in evaluating the urgency of emergency otolaryngology referrals. Blinded cross-sectional diagnostic reasoning study. Simulated emergency referral…
View details →Baudin, Pouyau, Subtil et al. · 2026 · JAMA
Prone positioning has been shown to improve respiratory mechanics and oxygenation, but its clinical benefit in infants with acute viral bronchiolitis receiving high-flow nasal cannula (HFNC) support remains unknown. To investigate whether…
View details →Tajika, Shitara, Hatori et al. · 2026 · JSES international
The forearm flexor-pronator muscle contributes to the dynamic stabilizer against valgus stress at the elbow during pitching motion. This study used shear wave ultrasonography to assess the relation between the elasticity of each forearm…
View details →Ku, Lee, Jung et al. · 2026 · Journal of animal science and technology
The gut microbiome of cattle suppresses pathogens and aids host immunity. However, the gut microbiome of newborn calves is still developing; therefore, diarrhea caused by pathogen infection is common. Rapid changes in the gut microbiome…
View details →Tang, Xu, Zhao et al. · 2026 · Journal of clinical ultrasound : JCU
To investigate the performance of an artificial intelligence (AI) diagnostic system for thyroid nodule sonography based on deep learning convolutional neural network (CNN). We retrospectively included 485 thyroid nodules with definite…
View details →Felix, Nagesh · 2026 · Turkish journal of orthodontics
The objective of the study was to compare the accuracy and fit of direct-printed and thermoformed aligners. The in vitro study included a pre-treatment scan as a reference model. Thirteen successive treatment stages were digitally planned…
View details →Ye, Lin, Lu et al. · 2026 · Annali italiani di chirurgia
Diabetic patients are at an increased risk for cataract and may experience delayed postoperative recovery due to diabetes-related ocular tissue vulnerability. However, the impact of preoperative glycemic control on early surgical outcomes…
View details →Büttner, Derman, Simonis et al. · 2026 · Clinical and experimental dental research
To evaluate serum IgG responses against Porphyromonas gingivalis gingipains RgpB and Kgp in patients with stage III and IV periodontitis and examine associations with clinical periodontal parameters. This exploratory cross-sectional study…
View details →Tong, Guo, Xia et al. · 2026 · Respiration; international review of thoracic diseases
Transbronchial lung cryobiopsy (TBLC) is increasingly used to diagnose interstitial lung disease (ILD). However, the learning curve associated with this technique remains unclear. This retrospective analysis included the first 100 patients…
View details →Chen, Xu, Yan et al. · 2026 · Surgical endoscopy
This multi-center study aimed to evaluate the clinical validity of the "up-to-seven" criteria (sum of tumor number and largest diameter ≤ 7) as an expanded threshold for curative liver resection in hepatocellular…
View details →Zhang, Li, Chen et al. · 2026 · Surgical endoscopy
Neoadjuvant therapy is recommended for hepatocellular carcinoma at advanced stages. It is unknown whether robotic liver resection (RLR) is superior to open liver resection (OLR) after neoadjuvant therapy. We analyzed consecutive RLR and…
View details →Rostamian, Moabedi, Poursalehi et al. · 2026 · Food & function
In this study, we evaluated the association between UPFs with HTGW in relation to oxidative stress and inflammation in Iranian adults, as no previous study had assessed these altogether. This cross-sectional study consisted of a sample of…
View details →Giuretis, Wootton, Gillanders et al. · 2026 · Marine pollution bulletin
Stormwater is increasingly recognised as a contributor to microplastic contamination in aquatic environments. Yet, the contribution of rainfall in flushing microplastics through urban drainage systems into coastal environments remains less…
View details →Esmaeilzadeh · 2026 · International journal of medical informatics
Patient portals provide direct access to clinical encounter data; however, comprehension barriers, especially for patients with limited health literacy, frequently prevent meaningful use, even for common acute conditions. Large language…
View details →Ozatak, Sonmez, Ozatak et al. · 2026 · The Journal of emergency medicine
Intravenous adenosine is the standard first-line therapy for stable supraventricular tachycardia (SVT). However, transient post-cardioversion sinus pauses frequently complicate its use, causing clinical anxiety. Patient-specific factors…
View details →Jia, Zhang, Pradeep et al. · 2026 · Journal of cardiovascular electrophysiology
Studies regarding sex and age differences in clinical outcomes of DCLP patients remain limited. This was a retrospective, single-center study, which evaluated the consecutive patients who underwent Aveir DCLP implantation between January…
View details →Balkaya, Göçer, Demirbuğa · 2026 · Odontology
This study aimed to evaluate the polymerization, contact angle, surface tension, antibacterial activity, and bonding properties of experimental adhesives modified with the addition of casein phosphopeptide-amorphous calcium phosphate…
View details →Tasgaonkar, Rathi, Agrawal et al. · 2026 · International journal of clinical pediatric dentistry
Preserving primary teeth with crowns is vital in pediatric dentistry, especially for those compromised by dental caries, previous treatments, or malformations. To address the limitations of traditional esthetic crowns, Bioflx crowns have…
View details →Rathee, Bhardwaj, Gupta et al. · 2026 · International journal of clinical pediatric dentistry
Anxiety and pain often lead to a challenging situation in a dental clinic. This study aimed to compare the efficacy of virtual reality (VR) glasses to conventional techniques for anxiety control in children. Jio Dive VR glasses (passive)…
View details →Teke, Ergen, Basaran et al. · 2026 · Pediatrics international : official journal of the Japan Pediatric Society
Duodenogastric reflux (DGR), the backward flow of duodenal contents into the stomach, is often overlooked in children. This study aimed to evaluate the endoscopic and histopathological changes in the esophagus associated with DGR in…
View details →Yıldırım, Aksoy, Özbilgin · 2026 · Turkiye parazitolojii dergisi
This study aimed to quantitatively assess the intracellular susceptibility of Leishmania tropica ( L. tropica ) to conventional antileishmanial drugs using the parasite rescue and transformation assay (PRTA), which involves controlled…
View details →Torii, Oshima, Aoki et al. · 2026 · Asian journal of endoscopic surgery
The hinotori surgical robot system, the first Japanese-made robotic-assisted surgical system to receive Japanese regulatory approval in 2020, is now being applied clinically in gynecology. This study aimed to comprehensively compare the…
View details →Liu, Zhang, Zhang et al. · 2026 · BMC surgery
To compare the clinical efficacy and safety of unilateral biportal endoscopy (UBE) versus percutaneous endoscopic interlaminar discectomy (PEID) in the treatment of highly downward-migrated lumbar disc herniation (HDM-LDH). A retrospective…
View details →Brilli, Giansanti, Altieri et al. · 2026 · Clinical oral investigations
This randomized clinical trial compared the accuracy of palatal paramedian miniscrew placement using static computer-assisted surgery (s-CAS) and dynamic computer-assisted surgery (d-CAS). Forty subjects (11-17 years) requiring palatal…
View details →Panda, Koch, Amineni · 2026 · Pest management science
The brown marmorated stink bug, Halyomorpha halys (BMSB), is an invasive polyphagous pest causing major losses in fruit and field crops in Europe and the Americas. With insecticide options increasingly limited by resistance and regulatory…
View details →Chen, Stoffels, Wang et al. · 2026 · Contraception
Compare differences in dilation and evacuation (D&E) outcomes after single-agent cervical preparation. We conducted a retrospective cohort study of patients receiving buccal misoprostol, oral mifepristone, or osmotic dilators prior to D&E…
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