11,326 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Anderson RE, Dolney NA · 2026 · Journal of child sexual abuse
The Sexual Experiences Survey (SES) is a widely used measure of sexual victimization. The most recent version of the SES, the Sexual Experiences Survey-Victimization (SES-V), released in 2024 is longer than prior versions. This raises…
View details →Alexandre Almeida, Vinícius Atti, Daniel Cecconi Agostini et al. · 2015 · Revista Brasileira de Ortopedia
OBJECTIVE: To analyze the results from arthroscopic suturing of large and extensive rotator cuff injuries, according to the patient's degree of osteopenia.METHOD: 138 patients who underwent arthroscopic suturing of large and extensive rotator cuff injuries between 2003 and 2011 were analyzed. Those operated from October 2008 onwards formed a prospective cohort, while the remainder formed a retrospective cohort. Also from October 2008 onwards, bone densitometry evaluation was requested at the time of the surgical treatment. For the patients operated before this date, densitometry examinations p
View details →Hsin-Hua Lee, Ming-Feng Hou, Shu-Yi Wei et al. · 2016 · PLoS ONE
To compare the long-term clinical outcomes of postmastectomy radiotherapy (PMRT) between breast cancer patients with and without immediate transverse rectus abdominis myocutaneous (TRAM) flap reconstruction.The study included 492 patients with stage II or III breast cancer who underwent modified radical mastectomy (MRM) and chemotherapy followed by PMRT between 1997 and 2011. Cox regression model and Kaplan-Meier curves were calculated, and the log-rank test was used to evaluate the differences between overall and disease-free survival rates in the 2 groups.Among 492 patients, 213 patients had
View details →Abbas Abbaszadegan, Zeinab Rafiee, Bahar Asheghi et al. · 2025 · PLoS ONE
Tooth discoloration caused by intracanal medicaments and irrigants presents a significant aesthetic challenge in dentistry. This study aimed to investigate the discoloration effects on tooth of nanographene oxide and positively charged silver nanoparticles and compares them with other commonly used materials in endodontic treatment. A total of 108 single-rooted, single-canal anterior mandibular and maxillary premolar teeth, extracted for orthodontic or periodontal reasons, were selected and prepared. The specimens were randomly divided into seven experimental groups and two control groups, eac
View details →Serpi M, Çakan A, Akpınar A · 2026 · Medical science monitor : international medical journal of experimental and clinical research
BACKGROUND Vertebral fractures result from degenerative, osteoporotic, or traumatic spinal loading. Treatment options include conservative management, segmental fusion, and percutaneous vertebroplasty/kyphoplasty (PVP/BKP) performed using…
View details →Đorđević Dragan, Lović Branko, Deljanin-Ilić Marina et al. · 2008 · Srpski Arhiv za Celokupno Lekarstvo
INTRODUCTION The prognostic significance of QTc dispersion changes during exercise testing (ET) in patients with left ventricular hypertrophy is not clear. OBJECTIVE The aim was to study the dynamics of QTc interval dispersion (QTcd) in patients (pts) with left ventricular hypertrophy (LVH) during the exercise testing and its prognostic significance. METHOD In the study we included 55 men (aged 53 years) with hypertensive left ventricular hypertrophy and a negative ET (LVH group), 20 men (aged 58 years) with a positive ET and 20 healthy men (aged 55 years). There was no statistically significa
View details →Kričković Zoran, Simatović Milan, Lukić Darko et al. · 2020 · Scripta Medica
Background/Aim: Benign prostatic hyperplasia (BPH) is a very common disease in older men. BPH involves the presence of signs of hyperplasia of the stromal and epithelial elements in the prostate with consequent enlargement of its volume. The aim of this study is to analyse the frequency of typical complications in the treatment of patients with benign prostatic hyperplasia and the effect of medicamentous treatment. Method: Patients diagnosed BPH were included in the prospective, one-year study. They were divided into 2 groups. The first group (30 patients) consisted of those ones, whose prosta
View details →Rokaya D, Al Jaghsi A, Masri M et al. · 2026 · Frontiers in dental medicine
Objectives This study aimed to investigate the accuracy of two intraoral scanners at different post space preparation depths and widths for CAD/CAM fabricated post and core fabrication. Methods A total of 36 extracted anterior teeth were…
View details →Malvandi H, Shamabadi MH, Vaezi I · 2026 · Bulletin of environmental contamination and toxicology
In the present study, thirteen urban bird species were used as bioindicators to monitor metal concentrations in the metropolis of Mashhad. The concentrations of lead (Pb), zinc (Zn), and copper (Cu) ranged from 0.004 to 0.073, 0.750 to…
View details →Zaharovs V, Pilmane M · 2026 · Journal of molecular histology
The anti-apoptotic genes DAD-1 and HAX-1 and the pro-apoptotic GZMB gene have a significant role in the regulation of apoptosis in heart tissue. However, investigation into these genes and their proteins in the pathogenesis of…
View details →Clukey J, Locascio J, Semler J et al. · 2026 · Journal of clinical gastroenterology
Goals We aimed to evaluate the efficacy and safety of IFT for the treatment of CC in a pilot randomized controlled trial (RCT). Background Subjects with refractory chronic constipation (CC) have limited treatment options. Interferential…
View details →Vatan A, Karabay O, Moralı H et al. · 2026 · BMC infectious diseases
Background Tenofovir alafenamide (TAF) is widely used in antiretroviral therapy due to its improved renal and bone safety compared to tenofovir disoproxil fumarate (TDF). However, concerns remain regarding its potential metabolic effects…
View details →Shikama T, Otaki Y, Kinoshita D et al. · 2026 · Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
Objective Nodular calcifications occupying the lumen in the femoropopliteal artery, known as "Black Rock (BR)" lesions, are associated with poor patency. We focused on the drug-coated balloon (DCB) and examined whether the impact of final…
View details →Wu G, Ou X, Zou M et al. · 2026 · Journal of cancer research and clinical oncology
OBJECTIVE: This study aimed to compare the outcomes of no-touch radiofrequency ablation (NT-RFA) and conventional RFA (C-RFA) in the treatment of solitary recurrent hepatocellular carcinoma (rHCC) ≤ 3 cm. METHODS: 255 patients with rHCC…
View details →Mostamand S, Merchant Q, Ji Y et al. · 2026 · Neurogastroenterology and motility
Background Anorectal manometry (ARM) is a commonly performed motility test in pediatrics. Currently, adult ARM normative data are extrapolated to pediatric assessments due to few validated pediatric studies. We share a single center…
View details →Salık M, Bakır EP · 2026 · Journal of functional biomaterials
Aim: The aim of this study was to comparatively evaluate the shear bond strengths between different calcium silicate-based biomaterials and glass ionomer-based restorative materials. Materials and Methods: In this in vitro study, a total…
View details →Liang H, Gui Y, Lv K et al. · 2026 · Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
Objective To compare the imaging efficacy and patient tolerability of a novel cellulose-based oral contrast agent with a conventional starch-based agent in gastric contrast-enhanced ultrasound,thus providing evidence-based support for…
View details →Šostakaitė G, Jauniškytė M, Budrys D et al. · 2026 · Nutrients
Background : Critically ill patients experience rapid muscle wasting during their ICU stay. Ultrasound (US) and bioelectrical impedance analysis (BIA) are widely used to assess muscle mass; however, their accuracy may be affected by fluid…
View details →Bellew S, Tjiattas-Saleski L, Butz D et al. · 2026 · The western journal of emergency medicine
Introduction Computed tomography (CT) is an essential diagnostic tool for evaluating emergency department (ED) patients. Between 15-20% of patients who present to the ED in the United States (US) undergo CT imaging. CT imaging with the use…
View details →Murphy C, Baglioni M, Lepage OM et al. · 2026 · The Veterinary record
Background To our knowledge, the effect of sedation with romifidine on the grading of laryngeal function in horses has not been studied. Our objective was to examine the effects of romifidine on the grading of laryngeal function and the…
View details →Liu H, Liu L, Zhao Z et al. · 2026 · Scientific reports
Psychological distress is a major public health issue with multisystemic effects, yet its multidimensional nature and specific links to urogenital disorders remain inadequately characterized due to methodological limitations of prior…
View details →Mirzaei R, Soleimanzadeh A, Asri-Rezaei S · 2026 · Scientific reports
Dog semen conservation at cold temperatures (5 °C) is a valuable reproductive management tool, but it is bedeviled by issues of oxidative stress and mitochondrial damage that reduce sperm quality and viability. Urolithin A (UA), a natural…
View details →Laffi A, Piras A, Meoni A et al. · 2026 · Biomedicines
Background: Exercise plays a crucial role in the prevention and management of type 2 diabetes. During self-motion, optic flow provides visual information about heading direction and influences postural control. This study investigated…
View details →Güngör ÖF, Ünal N, Paksoy Y · 2026 · Archives animal breeding
This study aimed to investigate the effects of pregnancy type, genotype, and parturition stage on sheep behavior. It also examined how pregnancy type and genotype influence labor characteristics. These evaluations were necessary because…
View details →Degli Antoni G, Gandolfi G, Soana MG · 2026 · Health policy (Amsterdam, Netherlands)
Background Financial anxiety has increased over the past decade, particularly among young people. While prior research has examined its determinants and consequences, coping strategies have been very poorly explored so far. Objective This…
View details →Shen LL, Shi BB, Xiong WY et al. · 2026 · Sheng li xue bao : [Acta physiologica Sinica]
This study aims to investigate whether the reduction in early embryonic development due to repeated controlled ovarian stimulation (COS) is associated with the expression levels of enzymes related to aerobic glycolysis. A repeated COS…
View details →Fujishima Y, Anderson D, Kamakura S et al. · 2026 · PNAS nexus
The lymphocyte culture method for chromosomal aberration analysis was established in the 1960s, and culture media supplemented with fetal bovine serum (FBS) have been routinely used. However, issues such as lot-to-lot variability,…
View details →Di Gregorio I, Migliaccio V, D'Elia M et al. · 2026 · Antioxidants (Basel, Switzerland)
Onion peel represents a valuable food by-product rich in bioactive phenolic compounds. Building on previous phytochemical investigations, an onion peel extract from the Rossa di Tropea variety was developed as a standardized bioactive…
View details →Moghtaderi F, Zimorovat A, Raeisi-Dehkordi H et al. · 2026 · Nutrition and health
BackgroundOxidative stress plays a critical role in the pathogenesis of chronic diseases. Canola oil (CO) and sesame oil (SO), due to their antioxidant constituents, may differentially influence oxidative stress biomarkers.AimThis study…
View details →Glei DA, Weinstein M · 2026 · Aging & mental health
Objectives The association between depression and cognition is well-established, but there is uncertainty regarding the direction of causation. We evaluated the relationship between depression and poor cognition in both directions. Method…
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