11,418 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Makiev EA, Kozhevnikova TN, Pronin AV et al. · 2026 · Voprosy virusologii
Objective To evaluate how influenza infection affects the hypolipidemic effect of a novel combined drug - Prenophytol based on polyisoprenoids (sodium polyprenyl phosphate and beta-sitosterol) in mice with experimental dyslipidemia.…
View details →Mohamed FB, Middleton DM, Manmatharayan A et al. · 2026 · Spinal cord
Study design (Phantom & Human) OBJECTIVE: The purpose of this study was to optimize imaging sequences to suppress artifacts induced by metallic hardware, using phantoms implanted with spinal hardware and participants with spinal cord…
View details →Tomczyk K, Yang-Jensen KC, Lorentzen LG et al. · 2026 · Scientific reports
Prasterone (dehydroepiandrosterone, DHEA) is increasingly used in the treatment of genitourinary syndrome of menopause (GSM), although its molecular effects on vaginal tissue remain insufficiently characterized. This prospective study…
View details →Wen YC, Chu FY, Wang TH et al. · 2026 · Clinical toxicology (Philadelphia, Pa.)
Introduction Hydrogen sulfide exposure is a major cause of occupational poisoning and is frequently associated with life-threatening effects. This study aimed to investigate the patterns, poisoning severity, and predictors of severity in…
View details →Li Y, Qin L, Wang Y et al. · 2026 · Reproductive health
Background Menopausal age is closely associated with women's health, but research on its association with sarcopenia risk remains insufficient. Our study aimed to explore how menopausal age affects the risk of sarcopenia in postmenopausal…
View details →Kiracı M, Soytürk G, Köş FT et al. · 2026 · BMC cancer
Background Anthracyclines can induce endothelial and microvascular injury that precedes measurable myocardial dysfunction. However, reliable early markers of such injury are lacking. Nailfold capillaroscopy (NFC) is a noninvasive imaging…
View details →Virkkunen V, Kero K, Stenholm S et al. · 2026 · Menopause (New York, N.Y.)
Objectives For many women, retirement represents a significant transition in late adulthood, which may result in many alterations in lifestyle habits and behavioral patterns. Several factors known to improve during the retirement…
View details →Woodworth E, Sheppard C, Wong R et al. · 2026 · Cureus
Background Following the transition to a single-accreditation residency system, Doctor of Osteopathic Medicine (DO) and Doctor of Allopathic Medicine (MD) students now apply for the same urology residency positions. Despite this…
View details →Swierkosz-Lenart K, Ranjbar S, Compagne C et al. · 2026 · The journal of ECT
Background Electroconvulsive therapy (ECT) is a widely used treatment for severe and treatment-resistant depression, with high efficacy but considerable interindividual variability of response. The neurophysiological mechanisms underlying…
View details →Barcaccia B, Cervin M, Borrelli DF et al. · 2026 · Journal of child psychology and psychiatry, and allied disciplines
Background Obsessive-compulsive symptoms (OCS) often emerge during childhood and adolescence, and two aetiological models have been proposed. According to the first model, maladaptive cognitive beliefs facilitate the transformation of…
View details →Miculka A, Imhoff R · 2026 · International review of social psychology
Despite the social nature of generalized political attitudes such as conspiracy mentality, right-wing authoritarianism (RWA), and social dominance orientation (SDO), dyadic phenomena concerning these attitudes have not been comprehensively…
View details →Wang Y, Li C, Zhang H et al. · 2026 · International journal for equity in health
BACKGROUND: Vision impairment is common among children and is known to affect learning, but its impact on children’s mental health has received less attention, especially in low- and middle-income countries. This study aims to focus on a…
View details →Khawaja SA, Hanna L, Singh A et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Background Stroke remains a significant concern in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). Despite advances in TAVI technology and techniques, rates have remained unchanged, with trials of Cerebral embolic…
View details →Wang J, Ma Y · 2026 · BMC ophthalmology
Background The efficacy and safety profile of the active-fluidics system (AFS) in diabetic cataract patients remains inadequately characterized. This study specifically evaluated AFS versus gravity-fluidics system (GFS) in type 2 diabetes…
View details →Reis AM, Barros AS, Poças PS et al. · 2026 · The Journal of sports medicine and physical fitness
Background Jumper's knee, also known as patellar tendinopathy, is a common overuse injury among athletes involved in sports that require repetitive jumping and high-impact activities, such as volleyball. Understanding the risk factors…
View details →Savaş EM, Bozkurt HH, Kemer NI et al. · 2026 · Leukemia research
Management of relapsed or refractory acute leukemia remains challenging, as allogeneic transplantation is the only curative option. Although targeted therapies are increasingly incorporated as bridge-to-transplant strategies in both AML…
View details →Pei LC, Wang T, Guo YJ et al. · 2026 · BMC pregnancy and childbirth
Background To evaluate the association between triple therapy (hydroxychloroquine sulfate, aspirin, and enoxaparin sodium) and pregnancy outcomes in patients with undifferentiated connective tissue disease (UCTD)-related recurrent…
View details →Karunainathan MG, Lee C, Zohalinejad KD et al. · 2026 · Acta ophthalmologica
Purpose To evaluate real-world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age-related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals,…
View details →London KS, Cherney A, Neupane S et al. · 2026 · The American journal of emergency medicine
Background Non-trauma center (NTC) emergency departments (EDs) play regular but underappreciated roles in the management of severely injured patients, yet many lack formal protocols to guide care. We describe the implementation and…
View details →Shirane K, Kitagawa N, Morishima R et al. · 2026 · Journal of pediatric surgery
Background Pulmonary metastasectomy can improve the survival of children with pulmonary metastases from solid tumors. However, preoperative imaging often suggests chest wall and/or mediastinal invasion, raising concerns about…
View details →Teng NMY, Vijayakumar B, Smith DJF et al. · 2026 · Access microbiology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was a global pandemic where infected individuals experienced mild or severe disease. Unfortunately, some patients who experienced severe disease also had lasting abnormalities.…
View details →Chang H, Hung YS, Kuo MC et al. · 2026 · Annals of hematology
The International Prognostic Index (IPI) is the classical assessment tool to evaluate prognosis of diffuse large B cell lymphoma (DLBCL). Although the IPI is simple, reproducible, well validated and widely utilized, it is not entirely…
View details →Ateş, Avşar · 2026 · Computers, informatics, nursing : CIN
Generation Z has grown up in the digital age, leading to different learning styles compared to previous generations. Therefore, traditional methods may not be sufficient to capture their attention. This study aimed to examine the effect of…
View details →Istrate, Van Gelder, Szőllősi et al. · 2026 · Intensive care medicine
Environmental sustainability has become a critical concern across various sectors, including education and healthcare. Professional training programmes, particularly in intensive care medicine, are essential for maintaining competency but…
View details →Tasdemir, Korkmaz, Durak et al. · 2026 · Turkish neurosurgery
To investigate lumbar motion and muscle change following hybrid surgery in adolescent idiopathic scoliosis (AIS). We conducted a prospective study design including 16 patients (14 female, 2 male) who underwent either hybrid surgery or…
View details →Park, Lee, Koo et al. · 2026 · Clinics in orthopedic surgery
It is well known that the posteromedial (PM) buttress plays an important biomechanical role in ensuring stability in unstable intertrochanteric (INT) fractures. However, the necessity for the fixation of PM fragments remains controversial.…
View details →Yi, Yoon, Lee et al. · 2026 · Cancer research and treatment
While triplet regimens are considered optimal for treatment of multiple myeloma (MM), the benefit of adding bortezomib to lenalidomide and dexamethasone remains prospective-wise unclear in elderly patients due to frailty and potential…
View details →Sucu, Dereli, Aksan et al. · 2026 · BMC pregnancy and childbirth
The aim was to investigate the association between salt consumption and preeclampsia, as well as the effects of salt consumption on proteinuria, fetal-maternal Doppler parameters, and neonatal outcomes. This case-control study was…
View details →Lasmanovich, Chepeliuk, Fihman et al. · 2026 · World journal of surgical oncology
Segmental ureterectomy (SU) is an established kidney-sparing strategy for upper tract urothelial carcinoma (UTUC), yet few studies have compared the standard open approach to the emerging robotic modality. We performed a clinical outcome…
View details →Berthelot, Audureau, Bouleti et al. · 2026 · Archives of cardiovascular diseases
The MonCœur smartphone application (app) was developed to meet the specific needs of individuals living with heart failure (HF). To evaluate whether the MonCœur smartphone app improves self-care at 6months in patients with HF,…
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