11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Tchitchinadze M, Milleron O, Eliahou L et al. · 2026 · The Annals of thoracic surgery
Background To evaluate the progress of care for patients with Marfan syndrome with FBN1 pathogenic variant carriers over the past 30 years. Methods Patients who visited the center were entered into a prospective registry. Aortic events…
View details →Masturov YA, Hogan WB, Regal S et al. · 2026 · Orthopedics
Background Traditional guidance after posterior-approach total hip arthroplasty (THA) recommends return to driving at 6-8 weeks. Muscle-sparing direct anterior THA (A-THA) may enable earlier recovery. Our objective was to assess brake…
View details →Galbiati F, Plessow F, Plummer L et al. · 2026 · Journal of neuroendocrinology
Arginine-vasopressin (AVP) deficiency (AVP-D) is caused by hypothalamic-pituitary damage of vasopressinergic neurons leading to polyuria and polydipsia. Diagnostic tests for AVP-D are limited by low accuracy and/or tolerability. Kisspeptin…
View details →Saiful Islam M, Fujimori T, Miyanaga T et al. · 2025 · Journal of physics. Condensed matter : an Institute of Physics journal
The encapsulation of sulfur (S) within single-walled carbon nanotubes (S@SWCNTs) provides a unique opportunity to stabilize and study the structure and bonding of one-dimensional sulfur chains, which do not exist in a free state. In this…
View details →Garrett JM, McCormick JJ, King KE et al. · 2026 · Experimental physiology
We examined whether seven consecutive days of warm-water immersion could elevate resting and exercise-induced levels of brain-derived neurotrophic factor (BDNF), irisin and klotho in older adults. These biomarkers support cognitive and…
View details →Hamada R, Tamaki A, Murao M et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Purpose Bioelectrical impedance analysis (BIA) has emerged as a simple, noninvasive method for evaluating skeletal muscle. However, BIA is sensitive to fluctuations in body water and can overestimate skeletal muscle mass, which may obscure…
View details →Bayle JY, Onen F, Onen SH · 2025 · Sleep & breathing = Schlaf & Atmung
PURPOSE: The impact of remote monitoring (RM) on the likelihood of continuing CPAP therapy in apneic patients remains unknown in the long term and was addressed by a comparative cohort analysis. METHODS: The probability of continuing CPAP…
View details →Knezek SB, Engelen MPKJ, Coyle KS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)
Background Adding leucine (LEU) to protein meals enhances protein anabolism, but excess LEU reduces valine (VAL) and isoleucine (ILE) plasma concentrations. We examined in older adults whether additional LEU added to an essential amino…
View details →Lohse B · 2026 · Journal of nutrition education and behavior
Objective Examine the change in eating competence (EatC) over time in adults and children; explore the relationship between parent and child EatC. Design Survey assessment at 4 timepoints up to 6 years after baseline. Setting Elementary…
View details →Gonzales K, Condori J, Fernández G et al. · 2026 · Immunobiology
Background Neurocysticercosis (NCC) is a parasitic infection of the central nervous system (CNS) caused by the larval form of Taenia solium. This disease provokes an inflammatory response that intensifies when the parasite dies. This study…
View details →Demir A, Tan H, Hacı İA et al. · 2026 · Allergologia et immunopathologia
The aim of this study was to evaluate the nutritional status, especially calcium deficiency, of breastfeeding mothers of infants diagnosed with cow's milk food protein-induced allergic proctocolitis (FPIAP) on an elimination diet and to…
View details →Kuwahara F, Harada K, Nagata M et al. · 2026 · Clinical and experimental nephrology
Background Zinc deficiency is widely recognized as a cause of anemia, but no studies have clarified the impact of zinc deficiency on achieving target hemoglobin levels in patients undergoing peritoneal dialysis (PD) and receiving high-dose…
View details →Souto CS, Pereira F, Carvalho A et al. · 2026 · The Knee
Background Revision total knee arthroplasty (rTKA) remains a technically demanding procedure, with re-revision representing a major clinical challenge. The role of reconstruction strategies, particularly the use of augments and metaphyseal…
View details →Kurkowski SC, Taleghani ER, McMillan P et al. · 2026 · Journal of orthopaedic trauma
Objectives To compare clinical outcomes between open reduction and internal fixation (ORIF) with or without Conventus intramedullary cage (CC) for proximal humerus fractures. Methods Design Retrospective cohort study. Setting Level 1…
View details →Hacımustafaoğlu F, Aras S, Çaykara Peran B et al. · 2026 · International journal of radiation biology
Aim This study aimed to investigate the differential biological responses in tongue and esophageal tissues induced by flattening filter (FF) and flattening filter-free (FFF) beams at varying dose rates, and to assess the radioprotective…
View details →Yavuz AY, Can F, Avci İ et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Aim Spinal meningiomas (SMs) account for approximately 25-40% of intradural extramedullary spinal tumors [1]. The classical symptomatology typically begins with pain, followed by motor and/or sensory deficits, gait disturbances, and…
View details →Molasy B, Zawolik-Kosek W, Gronowska A et al. · 2026 · Emergency radiology
Purpose To evaluate the clinical associations of admission non-contrast CT morphology in acute pancreatitis within a real-world emergency workflow. Materials and methods This retrospective observational cohort study included 264…
View details →Ahmad I, Khondker A, Rickard M et al. · 2026 · Journal of pediatric surgery
Background Testicular torsion in undescended testes (UDT) has poor salvage rates, but it remains unclear if the cryptorchid state itself confers an intrinsic disadvantage. We aimed to compare testicular salvage between UDT and descended…
View details →Moosavi D, Nejati N, Arcan C et al. · 2026 · Journal of the Academy of Nutrition and Dietetics
Background Plant-based diets have been associated with lower risks of chronic diseases; however, not all plant-based diets confer equal health benefits. Data-driven methods provide an opportunity to empirically identify distinct…
View details →Mustafa A, Wang D, Dutton C et al. · 2026 · The Journal of invasive cardiology
Objectives Transfemoral (TF) access for transcatheter aortic valve replacement (TAVR) may be challenging in patients with peripheral arterial disease (PAD). Alternative access through intra- and extrathoracic approaches can be performed.…
View details →Tasaki K, Hoshi S, Hiraoka T et al. · 2026 · Journal of clinical medicine
Background/Objectives: Lacrimal passage intubation is commonly used to treat lacrimal duct obstruction. However, conventional dacryoendoscopes, which are limited by their low resolution and comb-structure artifacts, pose challenges for…
View details →Ergün N, Karabulut SS, Türken M et al. · 2026 · Journal of fungi (Basel, Switzerland)
Candida auris is a multidrug-resistant fungal pathogen associated with high mortality in healthcare settings. Although colonization is recognized as the harbinger of invasive infection, predicting which patients will develop bloodstream…
View details →Abid H, Khan Y, Khan N et al. · 2026 · Journal of clinical medicine
Background: Angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) were historically considered contraindicated in severe aortic stenosis (AS) due to theoretical haemodynamic risks. Contemporary evidence…
View details →Uchida Y, Tateo S, Wakao M et al. · 2026 · European journal of haematology
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase…
View details →Carbonell Martínez A · 2026 · European annals of allergy and clinical immunology
Summary Background. Lipid transfer protein (LTP)-mediated food allergy represents one of the most severe and heterogeneous forms of IgE-mediated food allergy in Mediterranean populations. Although Pru p 3 is the main marker of LTP…
View details →Brothánková P, Faitlová H, Sitina M et al. · 2026 · ORL; journal for oto-rhino-laryngology and its related specialties
Aim The aim of this study was to assess the relationship between texture and the correct identification of gustatory stimuli (sweet, salty, bitter, and sour) in both healthy participants and patients with taste disorders. Patients and…
View details →Esposito G, Passeggia R, Cannata A et al. · 2026 · Healthcare (Basel, Switzerland)
Background: University counselling services provide essential support for students navigating critical academic phases. These services have proven to be successful in promoting long-term psychological well-being and student retention.…
View details →Sezgin ME, Kaya NB, Basarmak U et al. · 2026 · BMC psychology
Background AI literacy has become increasingly relevant in digitally mediated environments, yet its relationship with fear of missing out (FOMO) and nomophobia remains underexplored. Method The study used an exploratory design to examine…
View details →Kolachena V, Priyadarshi M, Singh P et al. · 2026 · Resuscitation
The optimum site of tactile stimulation (TS) during initial steps of neonatal resuscitation in the delivery room (DR) is not well-established. To compare the impact of three different sites of TS (back rub, trunk rub, and sole rub) on…
View details →Soyak B, Ozgul N · 2026 · Journal of cancer research and clinical oncology
Purpose To compare the clinicopathologic characteristics, dissemination patterns, and survival outcomes of uterine carcinosarcoma (CS) and grade 3 endometrioid adenocarcinoma (G3EAC), focusing on nodal distribution and the impact of…
View details →