11,418 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Hart HF, Patterson BE, Atkinson HF et al. · 2026 · Journal of sport rehabilitation
Context Weakness of the quadriceps and hamstrings often persists following rehabilitation after anterior cruciate ligament reconstruction (ACLR). Yet, recovery of the gastrocnemius muscle following ACLR remains unclear. Thus, we aimed to…
View details →Pitimada M, Chiumello D, Monte A et al. · 2026 · Journal of robotic surgery
To evaluate changes in acid-base equilibrium in plasma and urine according to the Stewart’s approach, in gas exchange and in respiratory mechanics during robotic-assisted surgery. Prospective observational study on patients undergoing…
View details →Dunseath GJ, Cheung WY, Luzio SD et al. · 2026 · Diabetes care
Objective To determine whether less invasive C-peptide tests, urine C-peptide-to-creatinine ratio (UCPCR) and dried blood spot (DBS), could replace the mixed-meal tolerance test (MMTT) in the context of an interventional clinical trial…
View details →Wu S, Liu Q, Li L et al. · 2025 · Agriculture, Ecosystems and Environment.
Forage production and quality, two crucial ecosystem functions of grasslands, often demonstrate a trade-off and are significantly affected by both grassland community characteristics and environmental factors. However, whether and how…
View details →de Almeida GN, de Jesus LG, Branco MEC et al. · 2026 · Journal of applied animal welfare science : JAAWS
Track devices can cause behavioral, physical, and physiological adverse effects, with individuals varying in how quickly they adapt to them. We examined behavioral effects of replica radio-collars on two captive psittacid species,…
View details →Huda MS, Margari N, Islam N et al. · 2026 · Obstetric medicine
Aims To determine the impact of tighter glycaemic targets for gestational diabetes. Methods Retrospective data analysis before and after introducing tighter glucose targets. Results In 2265 pregnancies there was no change in…
View details →Uzlu D, Erdöl H, Bulanık ÖB et al. · 2026 · BMC ophthalmology
Background The objective of this study was to evaluate the anatomical and functional outcomes of patients who underwent relaxing retinotomy or retinectomy for retinal detachment complicated by proliferative vitreoretinopathy. Methods The…
View details →Richardson AE, VanderKaay Tomasulo MM · 2026 · BMC psychology
Background The need to mentally rotate objects is common in everyday activities (e.g., driving, loading suitcases in a car, playing 3D video games) and in specific professions (e.g., air traffic controllers, mechanics, pilots, surgeons).…
View details →Crippa M, Turati M, Flumian C et al. · 2026 · Journal of ISAKOS : joint disorders & orthopaedic sports medicine
Introduction/objectives Pediatric anterior cruciate ligament reconstruction (ACLR) outcomes, particularly long-term functional recovery and return-to-sport (RTS), remain debated and have not been well characterized in skeletally immature…
View details →Morris AJ, McKinney WP, Roberts SA · 2026 · The New Zealand medical journal
Aim Our aim was to record current susceptibility results of genital yeast isolates and to compare the results to the previous report covering the period 2001-2015. Methods Genital yeast isolates had their antifungal susceptibility…
View details →Takeyama A, Imamura Y, Ichikawa Y et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To investigate long-term outcome of retinal displacement for 1 year after idiopathic macular hole (MH) surgery with internal limiting membrane (ILM) peeling and evaluate its association with basal MH size. Methods This…
View details →Berk AZ, Balaban O, Eman A et al. · 2026 · BMC anesthesiology
BACKGROUND/OBJECTIVE: Ultrasound-guided subclavian vein (SCV) catheterization offers an alternative approach to the classical jugular vein catheterization for central venous catheter placement. The objective of this study was to evaluate…
View details →Lee CH, Kim KH, Choi YJ et al. · 2026 · Scientific reports
This study investigates the effect of epiretinal membrane (ERM) removal in the combined hamartomas of the retina and retinal pigment epithelium (CHRRPE) patients. In this retrospective, comparative case series, 15 CHRRPE patients were…
View details →Leshno A, Levanon E, Singer R et al. · 2026 · Ophthalmology. Glaucoma
Purpose To evaluate whether the administration of topical steroids is beneficial after elective laser peripheral iridotomy (LPI). Design A prospective, randomized, double-masked, placebo-controlled clinical trial. Participants Twenty-eight…
View details →Cagnacci A, Xholli A, Gabbi L et al. · 2026 · The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Objective We investigated the metabolic profile induced by contraceptives containing body-identical oestrogens. Methods A literature search was made for articles on contraceptives with oestradiol/nomegestrol acetate (E2/NOMAc), oestradiol…
View details →Cassís-Nosthas ML, Vorácková FV, Dzib FT et al. · 2026 · Journal of visualized experiments : JoVE
Although the gut microbiota is generally stable, it can be influenced by antibiotic treatment. Rifaximin, which is used to treat gastrointestinal disorders, is frequently administered with probiotics to reduce the risk of dysbiosis.…
View details →Madsen SS, Asghar MS, Lindberg U et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)
Although general anaesthesia is a very common medical procedure, knowledge of how the brain physiologically recovers remains limited. In this randomized cross-over trial, we investigated brain physiology during recovery from general…
View details →Usai DS, Kudryavtseva O, Thomsen MB · 2026 · Journal of cardiovascular pharmacology
Abstract Human arterial blood pressure follows a circadian rhythm, where pressure is highest during the day and lowest during the night. Patients with hypertension can have either a preserved rhythm or a dampened rhythm with a lower…
View details →Rodrigues Santos LE, Elsangedy HM, Acevedo EO et al. · 2026 · Psychological reports
This study investigated the potential of Binaural Beats (BB) stimulations at Beta (20 Hz) and Gamma (40 Hz) frequencies to alter interoceptive accuracy (IAcc) and sensibility (ISen) in individuals with depressive symptoms. Fifty-two…
View details →Kapellas N, Alkhalil S, Senkal M · 2026 · Obesity surgery
INTRODUCTION: Accreditation systems are designed to standardize surgical care and improve outcomes in bariatric surgery, yet evidence on the effects of accreditation transitions within a single center is scarce. This study evaluated…
View details →Baştuğ O, Canpolat A, Kafadar D et al. · 2026 · American journal of perinatology
Objective This study aimed to evaluate the renal effects and safety of adjunct aminophylline therapy in neonates with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Study design This retrospective cohort…
View details →Kasai N, Ihara H, Iemitsu M et al. · 2026 · Experimental physiology
Prolonged sitting disrupts lower-limb endothelial and microvascular function, likely via reduced shear stress and blunted microvascular reactivity. We examined whether Tabata-style high-intensity interval training (HIIT) mitigates this…
View details →Ganss C, Jung K · 2026 · Journal of dentistry
Objectives To investigate Hawthorne-like research participation effects on toothbrushing-related plaque outcomes. The data source was a longitudinal flossing study without toothbrushing instruction. Methods This secondary analysis used…
View details →Nakamura S, Tajima S, Hirota T et al. · 2026 · International journal of hematology
Tacrolimus (TAC) is a pivotal immunosuppressant used to prevent graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation (HSCT). However, because lymphocytes express P-glycoprotein (P-gp), which actively effluxes…
View details →Hauken MA, Gjestad R, Sekse RJT et al. · 2026 · The journal of sexual medicine
Background Hyperbaric oxygen therapy (HBOT) is an established treatment for pelvic late radiation tissue injuries (LRTIs) in cancer survivors, yet its impact on sexual health outcomes has previously not been examined. Aim To investigate…
View details →Keesing F, LaDeau SL, Canham CD et al. · 2026 · The Journal of animal ecology
Pulsed resources, including mast production by forest trees, often have knock-on effects on consumer populations and their prey, predators, parasites and mutualists. Response by small rodents to fluctuating acorn production in temperate…
View details →Pechanova O, Bulkova R, Vrankova S et al. · 2025 · Physiological research
Short-term fructose exposure may perturb the nitric oxide (NO)/reactive oxygen species (ROS) balance before hemodynamic changes development. Male Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR) rats received 10 % fructose in…
View details →Adjekum R, Small SA, Chan S et al. · 2026 · American journal of audiology
Purpose Narrowband (NB) chirps have recently been of great interest in audiology for the electrophysiological assessment of hearing in infants, but clinicians have little information about these new stimuli and how they compare to more…
View details →Short C, Semple T, Abkir M et al. · 2026 · Thorax
Introduction The current cystic fibrosis (CF) care era, while hugely welcome, raises new challenges, particularly the need for more sensitive pulmonary outcome measures. Seeking further optimisation, we previously developed a Short…
View details →Mol BM, de Bresser CJM, de Kleijn PV et al. · 2026 · European stroke journal
Carotid endarterectomy (CEA) is performed to lower the long-term risk of stroke in patients with carotid stenosis. Data evaluating long-term outcomes after CEA are scarce, but crucial for accurately determining long-term benefits. We aimed…
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