11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Niu TT, Xin WJ · 2026 · International journal of ophthalmology
Aim To investigate the effect of intravitreal injection of dexamethasone (DEX) implants on the corneal morphology of young adults with central retinal vein occlusion (CRVO). Methods This was a retrospective study. The information of all…
View details →Balston AJ, Conti I, Darko S et al. · 2026 · Alcohol and alcoholism (Oxford, Oxfordshire)
Aims Hospital admissions are frequently alcohol related and are an opportunity for health promotion. Transient Elastography (TE), an ultrasound-based method of assessing liver health, may be beneficial when used by inpatient Alcohol Care…
View details →Duus CL, Nielsen SF, Hornstrup BG et al. · 2026 · Journal of clinical hypertension (Greenwich, Conn.)
Dietary sodium reduction affects blood pressure (BP), the renin-angiotensin-aldosterone system (RAAS) and natriuretic peptides. Whether baseline levels of these hormones impact BP response to sodium reduction remains unknown. Aldosterone…
View details →Russek LN, Di Bon J, Herbland A et al. · 2026 · Journal of multidisciplinary healthcare
Purpose This study evaluated whether an independent, online modified Pilates program alters function, interoception (internal body awareness), activity levels, and kinesiophobia (fear of movement) in people with symptomatic joint…
View details →Garside T, Udy A, Reade MC et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Introduction The Burns Registry of Australia and New Zealand (BRANZ) has been used to identify significant variation in burn injury management and outcomes across Australia and New Zealand. This study aimed to assess variation in clinical…
View details →Lefevere J, Cools W, Cools F · 2026 · Neonatology
Introduction Noninvasive neurally adjusted ventilatory assist (NIV-NAVA) is used in preterm infants as a synchronized and proportional mode of noninvasive ventilation. Finding the ideal NAVA level to support preterm infants remains…
View details →Kaş Alay G, Mutlu B · 2026 · Games for health journal
Objective To determine the effect of training children with familial Mediterranean fever (FMF) using a mobile game (MG) or training booklet (TB) on self-efficacy, symptom management, and quality of life (HRQoL) compared with a control…
View details →Konyukhov VN, Garanin AA, Kolsanov AV · 2026 · Kardiologiia
Aim To evaluate changes in speech signal parameters during treatment in patients with chronic heart failure (CHF) and to optimize a set of speech parameters that can be used for remote monitoring of patients' condition after…
View details →Erdoğan Ş, Tavat BC · 2025 · Physiology & behavior
Previous studies have suggested that time perception fluctuates throughout the day in relation to daily fluctuations of body temperature, and that there is a negative relationship between body temperature and time perception. The aim of…
View details →Murphy E, Poudel G, Dakhili AH et al. · 2026 · Addictive behaviors
Introduction Cannabis Use Disorder (CUD) can come with intense cravings, which can trigger compulsive use/relapse, underscored by anterior cingulate cortex (ACC) hyperactivity during cannabis cue-reactivity functional neuroimaging (fMRI)…
View details →Kim YJ, Kim C, Park J et al. · 2026 · Nutrients
Background/Objectives: This study examined the association between dietary acid load (DAL) and metabolic syndrome (MetS)-related parameters in Korean adults undergoing eating habit modification. Methods: Forty-eight Korean adults (≥19…
View details →Lev-Ari L, Mintz Malchi K, Ludmir E et al. · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
Background Childhood sexual abuse (CSA) is associated with significant psychiatric morbidity and has been reported at notable rates among Jewish Israeli women. Yet data regarding abuse characteristics, psychiatric history and longitudinal…
View details →Reil JC, Sequeira V, Coppée C et al. · 2026 · Circulation. Heart failure
Background Obstructive hypertrophic cardiomyopathy (oHCM) is characterized by left ventricular (LV) outflow tract obstruction, which increases afterload and chronically activates the Anrep response, a compensatory (afterload-driven) state…
View details →Shin J, Lee KH, Kim JW · 2026 · Journal of affective disorders
Background Given that anxiety is highly comorbid in depressive adolescents, understanding the neural pathways underlying concurrent depression and anxiety could provide potential targets for treatment. We aimed to investigate treatment…
View details →Tanaka S, Hirata K, Uramaru K et al. · 2026 · Journal of neuroendovascular therapy
Objective This study aimed to evaluate the feasibility and safety of a computer-controlled local anesthetic delivery device during transradial cerebral angiography and to descriptively assess procedural pain and hemodynamic changes in an…
View details →Yilmaz Y, Celik FB, Atici A et al. · 2026 · Journal of hypertension
Background The clinical relevance of tissue-selectivity among angiotensin-converting enzyme (ACE) inhibitors is debated. This study aimed to compare the effects of a lipophilic (quinapril) and a hydrophilic (lisinopril) ACE inhibitor on…
View details →Korkmaz YY, Gungor F, Kudas I et al. · 2026 · Journal of clinical medicine
Background : Patients undergoing pancreatoduodenectomy (PD) after preoperative percutaneous transhepatic biliary drainage (PTBD) frequently develop bacterobilia. While bile culture positivity has been variably linked to postoperative…
View details →Aguilera-Eguía R, Fuentes-Barría H, Avilés-Santos Y et al. · 2026 · Frontiers in sports and active living
Objective To describe sleep quality, perceived stress, and physical activity levels, as well as to identify the associations between these variables in fourth-year Kinesiology students at the Catholic University of the Most Holy Conception…
View details →Lech D, Maksymowicz R, Matysek J et al. · 2026 · Journal of clinical medicine
Background: Microvascular free flap reconstruction is an established method for the management of complex head and neck defects in pediatric patients. However, the influence of perioperative anesthetic management on flap outcome in this…
View details →Siddiqui TG, Simonsen THB, Lie Selle M et al. · 2026 · Scandinavian journal of primary health care
Background Z-hypnotics are commonly prescribed for insomnia, but their use in older adults is associated with an increased risk of adverse events. Aim We examined the long-term effect of brief intervention (BI) for inappropriate z-hypnotic…
View details →Hussain A, Shah TH, Bashir S et al. · 2026 · ERJ open research
Respiratory muscle training can be used in conjunction with CPAP or in situations precluding use of CPAP therapy. It should be used as a complimentary measure rather than an alternative to CPAP. https://bit.ly/3JqDDU7.
View details →van der Horst DEM, van Uden-Kraan CF, Stiggelbout AM et al. · 2026 · Patient education and counseling
Objective Effective patient-clinician communication is essential in chronic kidney disease (CKD) to support treatment adherence and slow down disease progression. In this proof-of-concept study we evaluated the effects of a CKD dashboard,…
View details →Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Reproduction in domestic animals = Zuchthygiene
This current work aimed to determine the impacts of melatonin implants on testicular artery blood flow and Doppler indices, in relation to hormonal profile in post-pubertal camels (Camelus dromedaries) under heat stress and non-breeding…
View details →Elad B, Lotan D, Richter I et al. · 2026 · Journal of cardiovascular pharmacology
Abstract Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using…
View details →Hafez E, Ashraf E, Saeed S et al. · 2026 · Cureus
Introduction Dental training requires prolonged static and forward-leaning working positions that may contribute to forward head posture. Forward head posture can be quantified using the craniovertebral angle (CVA) and may be associated…
View details →Margas Z, Borkowska A, Kowalski K et al. · 2026 · Nutrients
Background The effects of fasting on serum kynurenines (KYNs) have been reported; however, no data are available on whether fasting also modifies their urinary excretion. Kidney organic anion transporters are involved in KYNs excretion,…
View details →Ito R, Uchida M, Fujie S et al. · 2026 · European journal of applied physiology
Purpose This study aimed to examine the acute effects of continuous and interval cycling on salivary secretory immunoglobulin A (SIgA) and anti-microbial peptides. Methods In a randomized crossover trial, 12 healthy young untrained men (22…
View details →Kopple JD, Bross R, Ekramzadeh M et al. · 2025 · The American journal of clinical nutrition
Background Many studies show that intestinal phosphate binders reduce serum phosphorus concentrations in hyperphosphatemic patients with chronic kidney failure. To our knowledge, there are virtually no studies of the effect of these…
View details →Kuna M, Štefanović M, Barac E et al. · 2026 · International journal of molecular sciences
Having appropriate and meaningful diagnostic procedures is crucial in the approach to patients with chronic spontaneous urticaria (CSU), so we wanted to investigate relationships between CSU patients' common serum factors and clinical CSU…
View details →Egorova AM · 2026 · Vavilovskii zhurnal genetiki i selektsii
Stress phytohormones - salicylic and jasmonic acids - participate in the plant defense response. The increase in the content of these compounds during plant infection by pathogens leads to the activation of signaling pathways, ultimately…
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