11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
McQueen K, Sivle LD, Khodabandeloo B et al. · 2025 · Marine environmental research
Sparkers are seismic sources commonly used to survey the seabed in areas planned for offshore wind farms. The almost continuous sounds produced by sparkers, with most energy in the frequency range 50Hz - 4 kHz, are audible to both fish and…
View details →Béllo Carvalho R, Frangos C, Sonawane C et al. · 2026 · Journal of mammalogy
Animals in urban preserves experience both the security of protected habitats and the persistent anthropogenic disturbances of surrounding human-dominated landscapes. During the COVID-19 pandemic, lockdowns temporarily reduced human…
View details →Halleran M, Balsom AA, Gordon JL · 2026 · Journal of integrative and complementary medicine
Objectives Women experiencing infertility report heightened levels of anxiety, depression, and distress. However, access to affordable mental health care is limited in most areas of the world. Self-directed interventions, including…
View details →Kuroda K, Miyoshi H, Hamamoto K et al. · 2026 · The journal of obstetrics and gynaecology research
Aim More than half of patients with pelvic organ prolapse (POP) complain of lower urinary tract symptoms (LUTS), especially voiding difficulty. Surgical approaches such as laparoscopic sacrocolpopexy (LSC) and transvaginal mesh surgery…
View details →Roosimaa M, Ilumets H, Kaha T et al. · 2026 · Journal of wound care
Objective The objective of this trial was to compare the clinical performance and safety of a novel wound dressing containing silver and copper nanoparticles (Nanordica; Nanordica Medical OÜ, Estonia) (Ag/Cu) with the ionic silver-based…
View details →Agarwal R · 2026 · American journal of hypertension
Background The mechanism of hypertension associated with erythropoiesis-stimulating agents in chronic kidney disease (CKD) is complex and remains poorly understood. Methods Here, anemic hypertensive patients with CKD and well-controlled or…
View details →Tamburro MK, Carlson JA, Yen WK et al. · 2026 · Matrix biology : journal of the International Society for Matrix Biology
Tendon injuries account for considerable and escalating clinical burden. After injury, tendons heal poorly with persistent fibrovascular scar. Unlike healthy tendon which is type I collagen (COL1)-rich and highly-aligned, fibrovascular…
View details →Lisco A, Borgognone A, Vanpouille C et al. · 2026 · The Journal of infectious diseases
Background The cervicovaginal microbiome may affect HIV-1 susceptibility and can in turn influence the prevalence and clinical course of HIV-1 and other sexually transmitted diseases. As the determinants, immunological correlates and…
View details →Yin TK, Sengar N, Fang TY et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
PURPOSE: Fluctuating hearing loss in Ménière’s disease (MD) presents a key clinical challenge due to lack of reliable prognostic markers. The clinical value of transient-evoked otoacoustic emissions (TEOAEs) low-frequency components…
View details →Gkirgkiris K, Charalampaki E, Margioula E et al. · 2026 · Anaesthesia, critical care & pain medicine
Background stive heart failure may coexist and aggravate the non-cardiogenic pulmonary edema of acute respiratory distress syndrome (ARDS). Yet, patients with congestive heart failure are likely under-represented in ARDS trials. We aimed…
View details →Holian JA, Bolton MD, Wilson DI · 2025 · Current Research in Food Science
Addition of small amounts of glycerol to milk chocolate during the tempering stage can yield a product which exhibits enhanced mechanical strength and retards motion of the continuous phase (cocoa butter, a mixture of fats) of this dense…
View details →Janicijevic D, Cuevas-Aburto J, Zhang X et al. · 2026 · Journal of sports sciences
This randomised study compared mid-term effects of supersets (SS) and cluster sets (CL) on neuromuscular performance in amateur male basketball players. Thirty participants were allocated to SS (n = 15) or CL (n = 15) and completed a…
View details →Wen K, Yang B, Liu L et al. · 2026 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Purpose This study sought to determine whether specially-designed myopia control spectacle lenses had any effect on astigmatism in clinical practice. Methods Medical records of 74 patients (age: 6 to 12 years old) involving the use of…
View details →Kleberg JL, Nord M, Cervin M et al. · 2026 · Development and psychopathology
Treatment response in pediatric social anxiety disorder (SAD) is highly variable, and symptoms may be maintained by maladaptive attention. A previous study found that youth with SAD scan a more restricted area of faces than healthy…
View details →Vodapally M, Chan-Golston AM, Sandhu J et al. · 2026 · Respiratory medicine
Study objective This study investigated long-term adherence to continuous positive airway pressure (CPAP) therapy among adult patients with obstructive sleep apnea (OSA), with a focus on identifying associations between age, sex, residual…
View details →Wadström BN, Wulff AB, Pedersen KM et al. · 2026 · Atherosclerosis
Background and aims Elevated remnant lipoproteins are a causal risk factor for atherosclerotic cardiovascular disease. We tested the hypothesis that low-grade inflammation can explain part of the increased risk of peripheral artery disease…
View details →Talathi R, Juhasz V, Delgado M et al. · 2026 · The Journal of clinical endocrinology and metabolism
Context Data on the metabolic effects of contemporaneous gender-affirming hormone therapy (GAHT) are limited. Objective To characterize the metabolic effects of GAHT ie, estradiol with anti-androgen therapy. Design Prospective…
View details →Baranowska K, Dylewski R, Fugiel J et al. · 2026 · Experimental aging research
Background Recent studies highlight that cognitive processes involved in learning share neural pathways with those controlling fine motor skills. Building on this insight, the mini-EDUball method was developed to integrate cognitive and…
View details →Izumi M, Mizutani S, Fujimoto A et al. · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
Background Ageism among dental students can impede equitable geriatric care. Developing educational interventions to reduce profession-specific and general ageist attitudes is an urgent priority in aging societies. Objective To determine…
View details →Izadi N, Hill TD, Boe A et al. · 2025 · Frontiers in allergy
Background Across all age groups, asthma disproportionally affects inner-city underserved populations. Studies on the use of at-home spirometry and digital inhalers have limited real-world evaluation in pediatric asthma. Objectives In this…
View details →Takeyama M, Kimura F, Furukawa S et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia
Background Intra-cranial haemorrhage (ICH) in neonates with haemophilia A (HA) remains a serious perinatal complication. Prophylactic administration of emicizumab (Emi) to pregnant HA carriers has been discussed as a potential preventive…
View details →Lutz D, van den Berg C, Neill MG et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Objectives To investigate time spent completing neuromuscular training (NMT) exercises in youth soccer team warm-up across a season considering sex, level of play, session type, and coach exposure and awareness of NMT. Design…
View details →Ma J, Yang M, Wang B et al. · 2026 · Biomacromolecules
Peptide-protected gold nanoclusters (P-AuNCs) were ideal candidates for constructing antibacterial agents. However, the individual P-AuNCs could only exert limited target behavior and antibacterial efficiency. Herein, CA 2 R 5 /GSH-AuNCs…
View details →Endendijk JJ · 2025 · Psychological reports
Interventions in which people are exposed to counter-stereotypical role models are often used for breaking gender stereotypes. Most gender role-model interventions focus on adolescents and emerging adults. Yet, middle childhood might be a…
View details →Pathak BK, Maurya M, Mishra N et al. · 2026 · Clinical pediatrics
Microcytic hypochromic anemia is common in severe acute malnutrition (SAM) children, but macrocytic anemia (vitamin B12/folate deficiency) is not uncommon. Vitamin B12 deficiency leads to anemia and developmental slowing. We looked for the…
View details →Polman EMN, Rijsdijk KF, Cornelissen P et al. · 2026 · Ecosystems.
Water table management such as temporal flooding is an important strategy for influencing vegetation development and creating suitable habitat for wildlife in managed wetland systems. Water table fluctuations can also affect soil carbon…
View details →Bodegom ME, Hissink RJ, El Moumni M et al. · 2026 · Annals of vascular surgery
Background Carotid stenosis is traditionally considered a relatively stable condition between symptom onset and carotid endarterectomy. However, short-term changes in duplex-derived hemodynamic parameters may occur during the waiting…
View details →Li J, Wang Q, Xie N et al. · 2026 · Cognitive processing
In order to better adapt to spatial environments, individuals often establish a spatial frame of reference system to represent objects and their positions within a scene. This study utilized a partial scene recognition paradigm across…
View details →Beaudoin DL, Hassan AR, Shehu A et al. · 2026 · Communications biology
A fundamental feature of the visual system is its ability to detect image contrast. The contrast processing starts in the first synapse of the retina where parallel pathways are established to compute contrast to bright (ON pathway) and…
View details →Matsumoto N, Fujino M, Sekine H et al. · 2026 · Memory (Hove, England)
Researchers have suggested that interoception can trigger the retrieval of autobiographical memories or influence the subjective sense of retrieval mode (e.g., involuntary or voluntary). This study examined whether four sessions of…
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