11,324 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kerr S, Minatoguchi S, Dumitriu Carcoana AO et al. · 2026 · Cardiovascular intervention and therapeutics
This study evaluated the serial anatomical and morphological changes in de novo coronary lesions treated with a drug-coated balloon (DCB) using integrated-backscatter intravascular ultrasound (IB-IVUS). The aim of this study was to…
View details →Yamauchi Y, Tanaka R, Kawahira R et al. · 2026 · Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Introduction This study investigated the safety and efficacy of single-needle Rheocarna therapy for chronic limb-threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization…
View details →Tworzyanski EH, Mochizuki G · 2026 · Journal of motor behavior
Engaging in a cognitive dual-task while standing relies on the allocation of available cognitive resources. Automatic postural control is engaged while distracted; however, the use of automatic mechanisms and modulation of this…
View details →Kawahara T, Yamaoka Y, Fushimi K et al. · 2026 · Child abuse & neglect
Background Abusive head trauma (AHT) is a leading cause of fatal maltreatment in infancy. Objective To estimate the annual incidence of hospitalized AHT among infants in Japan from 2014 to 2022 and assess the impact of the COVID-19…
View details →Sterringer T, Sale C, Morozov A et al. · 2026 · Calcified tissue international
Exposure to low energy availability (LEA) can stimulate metabolic adaptations that have been shown to disrupt bone remodeling as suggested by suppressed markers of bone formation and/or increased markers of bone resorption. Previous…
View details →Pickler MC, Funderburk LK, Lee KM et al. · 2026 · Journal of strength and conditioning research
Abstract Pickler, MC, Funderburk, LK, Lee, KM, Bolden, LK, Chapman-Lopez, TJ, Heileson, JL, and Gallucci, AR. Observation of altered iron status development during noncompetitive season training in NCAA Division I female acrobatics &…
View details →Özcan Ulubeli P, Aydoğan Z, Karakaya Gojayev E et al. · 2026 · Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)
Introduction This study aimed to evaluate pain complaints, as well as voice and swallowing functions, in professional voice users, and to compare the effectiveness of three therapeutic approaches: vocal hygiene (VH), vocal function…
View details →Wang X, Xu Y, Lin X et al. · 2026 · Scientific reports
Left ventricular-arterial (V-A) coupling is a key determinant of cardiovascular performance, which integrates intrinsic myocardial contractility with ventricular afterload. Septic shock frequently disrupts this coupling, and norepinephrine…
View details →Maisto A, Sanders RGP, de Hemptinne A et al. · 2026 · Ultrasonics
In this work, we combine acoustic streaming measurements, direct vibration measurements and the theory of wave dispersion to interpret changes in acoustic streaming. The vibration dynamics of the PZT are studied under frequency sweeping…
View details →Kotenko O, Kozlovskaya N, Emirova K et al. · 2026 · Nephron
Background The objective of a multicentre, prospective, observational study of an eculizumab biosimilar (Elizaria®) was to analyse the efficacy and safety of long-term complement inhibitor therapy in patients with atypical haemolytic…
View details →Joswig H, Oreizi-Esfahani S, Medack S et al. · 2026 · World neurosurgery
Background Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, resulting in motor and nonmotor symptoms including diminished sleep quality and altered dream…
View details →Raza GS, Jokelainen J, Stenbäck V et al. · 2026 · PloS one
Physical activity (PA) has numerous positive health effects, including improvements in cognitive function. PA stimulates the release of glycosylphosphatidylinositol-specific phospholipase D1 (GPLD1) from the liver, resulting in hippocampal…
View details →Esen Öksüzoğlu M, Kabukçu HO · 2026 · BMC psychiatry
Background Sleep terror (ST) is a common NREM parasomnia in early childhood and may be associated with broader emotional and behavioral dysregulation. However, its links with psychopathological symptoms and nutritional biomarkers remain…
View details →Tcherner S, Durom E, Peters J et al. · 2026 · COPD
In patients with moderate-to-severe COPD, airway mucus-occlusions correlate with airflow limitation, exacerbation and mortality-risk. However, the clinical relevance of mucus-plugs in milder COPD is not well-understood. We evaluated…
View details →Huang F, Chen K · 2026 · Human factors
ObjectiveThis study investigated how affective characteristics of interruptions (valence and arousal) influence task resumptions and post-interruption performance in younger and middle-aged/older adults under different task…
View details →Steen AV, Simmering JA, Perik M et al. · 2026 · BJOG : an international journal of obstetrics and gynaecology
Objective To determine the anatomical effect of pessaries in the upright position in women with pelvic organ prolapse (POP). Design Prospective observational cohort study. Setting Outpatient clinic of our gynaecology department. Population…
View details →Rawat R, Abrahamson CW, Rogers K et al. · 2026 · The Laryngoscope
Objectives To evaluate the effects of swallowing therapy and cricopharyngeus (CP) muscle surgery on upper esophageal sphincter (UES) opening, oral intake, and airway protection in patients with absent UES opening following neurological…
View details →Ponissery Saidu S, Kross A, Dibattista M et al. · 2026 · The Journal of general physiology
Odorants in the inhaled air bind to odorant receptors embedded in cilia of olfactory receptor neurons, triggering the opening of the two ciliary olfactory transduction channels; first, a cationic heterotetrameric cAMP-gated channel,…
View details →Śliwińska A, Świtaj K, Durma AD · 2026 · Nuclear medicine review. Central & Eastern Europe
Background Neuroblastoma (NB) is the most common extracranial solid tumor in children. Metaiodobenzylguanidine (MIBG) selectively accumulates in adrenergic tissue, enabling its use for diagnostic imaging of NB. The implementation of new…
View details →Lehman A, Layton P, Mishkulin S et al. · 2026 · Sexually transmitted diseases
Doxycycline postexposure prophylaxis (doxyPEP) may affect RPR titers. We describe syphilis diagnosis following doxyPEP roll-out. Syphilis diagnoses decreased (3.4%-1.5%) among persons prescribed doxyPEP. Diagnosis without laboratory…
View details →Fenwick A, Glasheen BM, Cammarato A et al. · 2026 · Biophysical reports
Drosophila models have proven invaluable for studying skeletal and cardiac muscle diseases. While permeabilized indirect flight muscle (IFM) and jump muscle fibers from Drosophila yield insightful mechanical data, these preparations cannot…
View details →Graham RR, Salgado BE, Guerrero E et al. · 2026 · European journal of applied physiology
Purpose This pilot study examined whether collagen supplementation, via gelatin, influences indices of skeletal muscle recovery following strenuous exercise. Methods Using a double-blind, randomized, placebo-controlled design,…
View details →Costa D, Guerra A, Birreci D et al. · 2026 · Movement disorders : official journal of the Movement Disorder Society
Background Cervical dystonia (CD) is a movement disorder with a complex pathophysiology, including cerebellar abnormalities. Transcranial alternating current stimulation (tACS), a noninvasive neuromodulation technique capable of entraining…
View details →Giotakis AI, Steinbichler TB, Heppt H et al. · 2026 · The Journal of craniofacial surgery
The exact nasal changes caused by several types of maxillofacial surgery are not yet thoroughly understood. The aim of the present study was to determine the exact nasal airway changes caused by maxillary advancement and impaction. In a…
View details →Hostrup M, Jessen S, Tischer SG et al. · 2026 · Scandinavian journal of medicine & science in sports
Misuse of beta 2 -agonists to promote leanness is increasingly reported among young men undertaking resistance training. However, preclinical models demonstrate adverse cardiac remodeling with high-dose beta 2 -agonist. We investigated…
View details →Rostron ZPJ, Feller JA, McClelland JA et al. · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Objectives To determine the change in modified star excursion balance test scores in patients between 6 and 12 months following anterior cruciate ligament (ACL) reconstruction and the change in the proportion of patients who met…
View details →Hart HF, Patterson BE, Atkinson HF et al. · 2026 · Journal of sport rehabilitation
Context Weakness of the quadriceps and hamstrings often persists following rehabilitation after anterior cruciate ligament reconstruction (ACLR). Yet, recovery of the gastrocnemius muscle following ACLR remains unclear. Thus, we aimed to…
View details →Pitimada M, Chiumello D, Monte A et al. · 2026 · Journal of robotic surgery
To evaluate changes in acid-base equilibrium in plasma and urine according to the Stewart’s approach, in gas exchange and in respiratory mechanics during robotic-assisted surgery. Prospective observational study on patients undergoing…
View details →Dunseath GJ, Cheung WY, Luzio SD et al. · 2026 · Diabetes care
Objective To determine whether less invasive C-peptide tests, urine C-peptide-to-creatinine ratio (UCPCR) and dried blood spot (DBS), could replace the mixed-meal tolerance test (MMTT) in the context of an interventional clinical trial…
View details →Wu S, Liu Q, Li L et al. · 2025 · Agriculture, Ecosystems and Environment.
Forage production and quality, two crucial ecosystem functions of grasslands, often demonstrate a trade-off and are significantly affected by both grassland community characteristics and environmental factors. However, whether and how…
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