11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Cozzi NV · 2026 · Naunyn-Schmiedeberg's archives of pharmacology
The aim of this study was to investigate the effects of deuterium substitution on the in vitro pharmacology of the psychedelic drug 2-(4-bromo-2,5-dimethoxyphenyl)ethan-1-amine (2C-B). Two deuterated isotopologues of 2C-B, namely…
View details →Lidborg LH, Kohen Tuncer D, Burton AM et al. · 2026 · Biological psychology
Theoretical models of face processing incorporate within-pool inhibition - a mechanism by which representations compete with one another to support recognition. However, direct evidence for these inhibitory mechanisms is sparse in studies…
View details →Boxer B, Zhang Z, Folland JP et al. · 2026 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Impact and resistance exercise have potent osteogenic effects and may positively affect cartilage through tissue deformation. These effects may be mediated through inhibitors of Wnt signaling, such as sclerostin and Dickkopf WNT signaling…
View details →Ashmore S, Russo D, Hornbach A et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Surgeons traditionally place the synthetic midurethral sling (MUS) after completing the apical suspension procedure during surgical procedures for pelvic organ prolapse (POP) and stress urinary incontinence (SUI). We hypothesize…
View details →Çetin OG, Gülgöz S · 2026 · Memory (Hove, England)
The role of agency in collective memory is largely unexplored, and evidence that schema-congruent collective events are more readily integrated than incongruent ones remains largely correlational. Studying these factors experimentally is…
View details →Kawasaki Y, Suzuki Y, Miyazaki K et al. · 2026 · Fukushima journal of medical science
Aim To clarify the change in characteristics and body mass index standard deviation (BMI-SD) after guanfacine extended-release (GXR) administration for attention-deficit/hyperactivity disorder (ADHD) children, we undertook a clinical…
View details →Pugina G, Tardivo C, Monus B et al. · 2026 · Scientific reports
Citrus production in Florida has declined drastically due to Huanglongbing (HLB), a bacterial disease associated with Candidatus Liberibacter asiaticus. This disease significantly reduces fruit yield and quality and shortens the tree's…
View details →Ortiz-Moriano MP, Rivas-Iglesias L, Gutierrez-Rodriguez A et al. · 2026 · Marine pollution bulletin
Invasive species tolerant to pollution may gain a competitive advantage in contaminated environments. This study aimed to assess the accumulation of microplastics (MPs) and heavy metals (HMs) in native (Mytilus galloprovincialis) and…
View details →Stein J, Kirschbaum C, Korb FM et al. · 2026 · Journal of cognitive neuroscience
Successfully exerting self-control is an important prerequisite for adaptive decision-making in daily life. The experience of acute stress might impair the ability to select actions in line with personally valued long-term goals in…
View details →Vu VA, Kim YB, Kim SK et al. · 2026 · Animals : an open access journal from MDPI
This experiment was designed to determine the effect of the Lacticaseibacillus paracasei ( paracasei ) strain NSMJ27, isolated from Korean fermented vegetable food (home-made kimchi), on laying performance, egg quality, intestinal…
View details →Pucetti P, Silva JT, Alves JB et al. · 2026 · Animal Feed Science and Technology.
The objective of this study was to evaluate the effects of different backgrounding durations in an intense postweaning production system for Nellore bulls, as compared with immediate adaptation to a corn-based finishing diet. Forty bulls…
View details →Zhang Y, Zhang H, Wang Y et al. · 2026 · Cognitive processing
The influence of the interaction between accent and learning styles on learners' learning is an important issue to be considered in online animation design and application. The objective of this study is to reveal the effects of accent and…
View details →Folliard NT, Waters SM, Roskam E et al. · 2026 · Animal : an international journal of animal bioscience
The global methane (CH 4 ) pledge aims to reduce anthropogenic CH 4 emissions by 30% by 2030. Oilseed rape (Brassica napus L), a break crop with 40 million ha cultivated globally in 2022, produces fatty acid-rich by-products that could…
View details →Moussiaux IG, Vandevoorde T, Robinson M et al. · 2026 · Journal of dairy science
Increasing frequency of severe weather events such as droughts and floods may reduce the inventory of high-quality forage available for feeding dairy cattle. Thus, optimizing rumen health and milk production when feeding reduced-forage…
View details →Lu C, Gil D, Lefeuvre M et al. · 2026 · The Journal of experimental biology
Climate variability and unpredictability present animals with challenging physiological and behavioural demands. However, empirical studies on endotherms involving manipulated environmental variability remain limited. This study…
View details →Niemann AS, Ramon R, Mayor J et al. · 2026 · Life (Basel, Switzerland)
(1) Background: The reconstruction of periacetabular defects after tumor resection remains one of the most challenging procedures in orthopaedic oncology. The modular LUMiC ® system was designed to improve fixation stability and reduce…
View details →Koumpias AM, Kirch M, Steppe E et al. · 2026 · Journal of women's health (2002)
Background Obtaining a National Institutes of Health (NIH) career development (K) award is a pivotal milestone for early-career faculty, contributing not only to individual career progression but also to the diversity of the biomedical…
View details →Comlekci M, Yıldız AE, Demirel A · 2026 · BMC sports science, medicine & rehabilitation
Background Ankle sprains are among the most common injuries in athletes, accounting for approximately 80% of all athletic injuries. Recurrent ankle sprains often progress to chronic ankle instability (CAI), which can impair athletic…
View details →Abdelnaby EA, Alhaider AK, Emam IA · 2026 · Veterinary sciences
This current study aimed to determine the impact of Mitoquinone (MitoQ) on the quality of frozen-thawed donkey semen. Ejaculates were collected from six male donkeys ( Equus asinus ), and ejaculates were polled and aliquoted into 12…
View details →Trakarnvanich T, Nochaiwong S, Ruengorn C et al. · 2026 · Scientific reports
To date, little is known regarding the treatment effects of different timed-dosing antihypertensive medications among hypertensive patients with albuminuria. We aimed to investigate whether morning or evening dosing of antihypertensive…
View details →Ünlü Ö, Görücü J · 2026 · Lasers in surgery and medicine
Objective The effectiveness of laser-etching (LE) on dentin shear bond strength (SBS) of universal adhesives remains unclear. This study aimed to compare the SBS of a nanohybrid composite resin to superficial and deep dentin following…
View details →Liu JY, Cooke JRH, Selen LPJ et al. · 2026 · The European journal of neuroscience
There are multiple methods for controlling dynamical systems under external disturbances, with some emphasizing robust performance and others prioritizing efficiency. Here, we characterized the control strategies of human steering behavior…
View details →Lee H, Sung JY, Son J et al. · 2026 · Journal of animal science and technology
In the modern swine production systems, pigs are often challenged with regrouping and vaccination, which may negatively affect growth performance and behavior of pigs. The objective was to test the hypothesis that a supplemental…
View details →Schimmele T, Castaneda NM, Mazzari G et al. · 2026 · Neuroimmunomodulation
Early life adversity (ELA) is a potent risk factor for negative mental health outcomes, in part through its enduring effects on neuroimmune function. The hippocampus is particularly sensitive to stress across the lifespan, and…
View details →Charoenphannathon JS, Royce SG, Higham Y et al. · 2026 · British journal of pharmacology
Background and purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell-derived extracellular vesicles…
View details →Maddahi N, Zamani B, Nadjarzadeh A et al. · 2026 · Urology journal
Purpose This study investigated the impact of synbiotics on blood and urinary concentrations of factors related to kidney stone formation in overweight or obese patients with hyperoxaluria. Materials and methods A randomized double-blind…
View details →Mishukov AA, Ignatova AA, Ogneva AL et al. · 2026 · Cytometry. Part A : the journal of the International Society for Analytical Cytology
Increasing evidence suggests connection between mitochondrial dysfunction and platelet-related disorders, necessitating developing of a high throughput method for assessing the functioning of mitochondria in platelets. Here we develop an…
View details →Alaoui-Ismaili Z, Grand J, Frydland M et al. · 2026 · Resuscitation plus
Background Early risk assessment is crucial in comatose survivors of out-of-hospital cardiac arrest (OHCA) for timely resource allocation and initiation of interventions. Neutrophil gelatinase-associated lipocalin (NGAL) is an inflammatory…
View details →Fida TT, Sherman T, Hall M et al. · 2026 · Biofouling
Acid-producing bacteria (APB) play significant role in pipeline corrosion by producing corrosive metabolites. Current APB mitigation strategies are often unsuccessful, costly, or not environmentally friendly. In this study, nitrate was…
View details →Randunu RS, Huber LA, Van Vliet BN et al. · 2026 · The Journal of nutrition
Background Developmental programming is a key determinant of adult hypertension. Total parenteral nutrition (TPN) can exert nutritional stress during development and cause irreversible programming of metabolism via epigenetic…
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