11,322 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Fusani B, Cardoso SD, Ramos A et al. · 2026 · General and comparative endocrinology
The looming stimulus is a widely used paradigm for investigating defensive behaviours in prey-predator contexts, as it simulates an approaching threat through the rapid expansion of a dark disk. Such stimuli typically evoke fight, flight,…
View details →Acho-Martínez YC, Hernández-García PA, Espinosa-Ayala E et al. · 2026 · Veterinary sciences
The objective of this study was to evaluate the effects of dietary inclusion of increasing levels of soybean oil on milk yield, milk composition, and milk fatty acid profile in dairy cows. The experiment was designed as a 4 × 4 double…
View details →Yang Y, Hou M, Li M et al. · 2026 · Current research in toxicology
Background Due to its ability to inhibit the growth of hepatoma cells, brefeldin A (BFA) has been considered a promising drug candidate for liver cancer. However, there is limited research on its safety profile and potential impacts when…
View details →McCarthy KM, Pierce KM, McKay ZC et al. · 2026 · Journal of dairy science
Concentrate feeds with a lower CP concentration are an effective means of reducing nitrogen (N) excretion from grazing dairy cows. Typically, imported feedstuffs such as soybean meal and maize are included in concentrate feeds to increase…
View details →Hackworth EE, Lastovich J, Carroll DM et al. · 2026 · Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Introduction In January 2025, the US FDA announced a proposed rule for a reduced nicotine standard (RNS) in cigarettes. Evidence suggests that the use of very low nicotine content (VLNC) cigarettes decreases cigarette use and tobacco…
View details →Laporte M, Casper AM · 2026 · CBE life sciences education
Course-based undergraduate research experiences (CURE) have been proposed as a mechanism to increase persistence in science. However, most evidence for their impact comes from self-reported surveys conducted under conditions of volunteer…
View details →Alhabli I, Ishaque N, Kate M et al. · 2026 · Journal of neurointerventional surgery
Background Thrombus migration can occur in patients receiving IV thrombolysis for acute stroke. This study compared the effects of IV tenecteplase (0.25 mg/kg) versus alteplase (0.9 mg/kg) on thrombus movement in patients undergoing…
View details →Costa A, Mulas O, Greco M et al. · 2026 · Annals of hematology
There is growing interest in the association between autoimmune diseases (AID) and myeloproliferative neoplasms (MPN), yet the specific clinical and prognostic implications of AID in myelofibrosis (MF) remain insufficiently characterized.…
View details →Wienholz A, Nuhbalaoglu-Ayan D, Mani N et al. · 2026 · Journal of psycholinguistic research
The processing of referential expressions is influenced by their form, but also by the accessibility of their antecedents. In sign languages, discourse referents are typically assigned to referential loci (R-loci) in the signing space,…
View details →Pięta A, Mazur-Kurach P, Maciejczyk M et al. · 2026 · Scientific reports
The Paleolithic diet (PD) has positive effects on health status and body composition. The Paleo diet has been also used to assess the effects on handball players performance but the association of adherence to PD and resting metabolic rate…
View details →Gul E, Doğan ÖT, Taş N et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives: It is well established that obstructive sleep apnea syndrome (OSAS) is associated with functional lung volumes. The aim of this study was to investigate the relationship between morphological lung volume and the…
View details →Cristobal M, Utterback PL, Stein HH et al. · 2025 · Poultry Science
The objective was to evaluate the nutritional value of conventional soybean meal (SBM-CV), fermented SBM-CV (FSBM), full-fat soybeans (FFSB), and fermented FFSB (FFFSB). In Experiments 1 and 2, two precision-fed rooster assays were…
View details →Massie S, Léguillette R, Jones JH et al. · 2026 · Journal of veterinary internal medicine
Background Maximal intensity exercise in equine athletes induces pulmonary capillary stress failure and exercise-induced pulmonary hemorrhage (EIPH) secondary to excessive transmural pressure (Ptm). Furosemide decreases EIPH severity and…
View details →Orr L, Golding H, O'Brien E et al. · 2026 · Genetics
Autophagy has emerged as a potential drug target for enhancing the efficacy of radiotherapy, but its precise role in cellular responses to ionizing radiation (IR) remains incompletely understood. To address this, we conducted a focused RNA…
View details →Koska D, Biermann N, Maiwald C · 2026 · Journal of biomechanics
Generalized Procrustes Analysis (GPA) is used for rigid alignment in statistical shape modeling to remove positional and size variation prior to Principal Component Analysis (PCA). GPA assumes isotropic variation, which is violated in…
View details →Bonatto IDC, Cavali M, Belli IM et al. · 2026 · Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA
The generation of municipal solid waste (MSW) has risen sharply, posing increasingly complex environmental challenges, particularly in its final disposal in landfills. Among the various contaminants present in MSW, emerging pollutants such…
View details →Silva GA, Reis-Silva LL, Gomes-de-Souza L et al. · 2026 · Pflugers Archiv : European journal of physiology
The lateral hypothalamus (LH) is a key brain region involved in integrating cardiovascular and autonomic components of the stress response, yet the local neurochemical mechanisms governing these functions remain poorly understood. This…
View details →Yang B, Guo Z, Zhou Q et al. · 2026 · Animals : an open access journal from MDPI
The lateral line is a highly differentiated skin sensory organ in fish, but few studies have explored the relationship between stocking density and the physiological responses of the lateral line in different species. In this study, grass…
View details →Post B, Chowhury P, Harris A et al. · 2026 · Medical care
Objectives To determine if hospital-orthopedist integration is associated with larger or smaller race and ethnicity gaps in the utilization of total knee arthroplasty (knee replacement) and physical therapy among Medicare beneficiaries.…
View details →Hu W, Shimoda H, Hayasaka D · 2026 · Research in veterinary science
Animal gastrointestinal coronaviruses such as porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) can cause oral infection despite being enveloped viruses, implying that they are capable of passing through…
View details →Banga A, Valentine V, Zhang S et al. · 2026 · American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Despite more complex procurement logistics under Continuous Distribution (CD), lung transplant (LT) outcomes appear better. The current analysis sought to investigate the potential contributors to these trends observed under the CD…
View details →Evsyukova VS, Sorokin IE, Kulikov PA et al. · 2026 · Bulletin of experimental biology and medicine
The removal of the cuticular membrane (chorion) in developing Danio rerio embryos was used as a model of mild and long-acting influences to study their consequences for adult D. rerio. We studied the effect of dechorionation 12 h after…
View details →Sargent C, Halson SL, Morrison M et al. · 2026 · Sensors (Basel, Switzerland)
There is some evidence to indicate that lower-body compression garments aid recovery from exercise by improving sleep quality, but this evidence is based on measures derived from self-reports and accelerometers. The aim of this study was…
View details →Wheeler GL, Steinman SA · 2026 · Frontiers in psychology
Introduction According to cognitive models, individuals with social anxiety place excessive importance on gaging others' reactions to their social performance. This may lead to misinterpretation of facial expression. Facial interpretation…
View details →Tanaka Y, Ishikawa K, Okubo M · 2026 · Psychological research
Previous studies using gaze-cueing tasks have reported mixed findings regarding how face masks affect gaze-triggered attentional processes. However, in those tasks, participants were explicitly instructed to ignore gaze and face stimuli,…
View details →Cozzi NV · 2026 · Naunyn-Schmiedeberg's archives of pharmacology
The aim of this study was to investigate the effects of deuterium substitution on the in vitro pharmacology of the psychedelic drug 2-(4-bromo-2,5-dimethoxyphenyl)ethan-1-amine (2C-B). Two deuterated isotopologues of 2C-B, namely…
View details →Lidborg LH, Kohen Tuncer D, Burton AM et al. · 2026 · Biological psychology
Theoretical models of face processing incorporate within-pool inhibition - a mechanism by which representations compete with one another to support recognition. However, direct evidence for these inhibitory mechanisms is sparse in studies…
View details →Boxer B, Zhang Z, Folland JP et al. · 2026 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Impact and resistance exercise have potent osteogenic effects and may positively affect cartilage through tissue deformation. These effects may be mediated through inhibitors of Wnt signaling, such as sclerostin and Dickkopf WNT signaling…
View details →Ashmore S, Russo D, Hornbach A et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Surgeons traditionally place the synthetic midurethral sling (MUS) after completing the apical suspension procedure during surgical procedures for pelvic organ prolapse (POP) and stress urinary incontinence (SUI). We hypothesize…
View details →Çetin OG, Gülgöz S · 2026 · Memory (Hove, England)
The role of agency in collective memory is largely unexplored, and evidence that schema-congruent collective events are more readily integrated than incongruent ones remains largely correlational. Studying these factors experimentally is…
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