11,322 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Dumlu B, Bölükbaşi ŞC, Bayir A · 2026 · Lipids
We investigated molecular characteristics and tissue distribution of elongation of very long chain fatty acids (ELOVL) genes in the chicken (Gallus gallus) genome. The research specifically examines the expression levels of these genes in…
View details →Barretto R, Sonnenfeld MM, da Silva RCM et al. · 2026 · Journal of robotic surgery
Objective To evaluate whether the use of intraoperative indocyanine green (ICG) fluorescence impacts anastomotic safety and surgical outcomes in patients undergoing bowel endometriosis resection. Methods Retrospective, multicenter…
View details →Mihara A, Iwanaga R, Muramatsu K et al. · 2025 · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
Background Metastatic bone tumors in solid cancer often induce excessive local bone resorption leading to skeletal related events (SRE) which may impact patients' quality of life and survival of the primary cancer. Denosumab, a bone…
View details →Weber MD, Frankenberger W, Ullman AJ et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background Paediatric critically ill patients are at risk of harm from central venous catheter overuse. We applied an implementation science approach to promote appropriate use of midline catheters. The aim of this study was to evaluate…
View details →Jones RW · 2025 · Potato Res..
Interest in phytomelatonin biosynthesis and activity has increased due to apparent effects on enhancing resistance to biotic and abiotic stress. Activity related to biotic stress has been associated with increased salicylic acid production…
View details →Jensen K, Secher EL, Libermann RH et al. · 2025 · European clinical respiratory journal
Introduction The RheOx system delivers brief, high-voltage electrical pulses to the airway lining, promoting the regeneration of healthy tissue and reducing mucus production in COPD patients with chronic bronchitis. The procedure, called…
View details →Tsujio G, Yashiro M, Miki Y et al. · 2026 · PloS one
Background Our group revealed that the combination of intra-operative stamp cytology and peritoneal lavage cytology (CY) improved the identification of individuals with high risk of peritoneal metastasis. In this exploratory Phase II…
View details →Lee D, Lee H, Lee C et al. · 2026 · Anesthesia and analgesia
Background Drug-induced dreams during intravenous sedation vary by pharmacological agent and influence patient experiences, yet the role of preoperative positive suggestions in modulating these dreams is unclear. This study aimed to…
View details →Niecestro R, Foster EC, Millist L et al. · 2026 · European journal of drug metabolism and pharmacokinetics
Background and objectives ES-481 is a potent and selective antagonist of the transmembrane alpha-amino-3-hydroxy-5-methyl-4 isoxazolepropionic acid (AMPA) receptor regulatory protein (TARP)-y8-dependent AMPA receptor being developed for…
View details →Albajri E, Ayaz H, Shewokis PA et al. · 2026 · Appetite
Objective To investigate how shifting the attention away from food being eaten (by women who are cognitively restrained) toward another food-related stimulus affects food intake and relative increases in neural activity from baseline (as…
View details →Voloshchuk R, Halushko A · 2026 · Journal of pain research
Background Surgical treatment of combat injuries often requires continuous analgesia for many weeks, which can be achieved with continuous peripheral nerve blocks. Existing data on the safety and efficacy of sciatic nerve catheterization…
View details →Anan M, Kagawa K, Okamatsu-Ogura Y et al. · 2026 · Physiology & behavior
The nausea and vomiting of pregnancy (NVP) affect many pregnant women's quality of life, and the underlying mechanisms are still unclear. Human chorionic gonadotropin (hCG) is suspected to be a factor in exacerbating NVP due to its…
View details →Awolaran O, Youssef F, Skakum M et al. · 2026 · Journal of pediatric surgery
Background Suction is frequently used on chest tubes draining parapneumonic effusions, but its impact on clinical progression remains uncertain. While suction may expedite drainage, it might also delay healing by perpetuating leaks or…
View details →Goričan I, Šorgo A, Strnad M · 2026 · Healthcare (Basel, Switzerland)
Background and Objectives: Slovenia, like many other European nations, has introduced voluntary first responders to enhance survival rates in out-of-hospital cardiac arrests. In currently published research, no conclusive data exists on…
View details →González-Llera L, Santos-Durán GN, Vences A et al. · 2026 · Scientific reports
Spinal cord injuries (SCIs) often result in permanent disabilities in humans. One major reason for the lack of recovery is the inability of adult mammalian descending neurons to regenerate their axons after injury. In contrast, several…
View details →Suarez-Baquero DE, Boido D, Assali A et al. · 2026 · Nature communications
In brain gray matter, neurovascular coupling (NVC) maintains brain metabolism homeostasis by modulating blood flow according to neuronal activity. In white matter, the energy cost of information transmission along myelinated axons is…
View details →Ceja G, Spencer J, Crawford S et al. · 2026 · Journal of dairy science
The objective of this study was to quantify state-level differences in milk yield, milk component yields, and lactation curve characteristics across 8 major US dairy states, and to determine whether temperature-humidity index (THI)…
View details →Shaw JR, Gray H, Xu Y et al. · 2026 · Blood advances
Prothrombin complex concentrates (PCC) are used off-label to treat direct factor Xa inhibitor (FXaI)-associated bleeding or before urgent surgery. GAUGE was a prospective observational cohort study of the effects of PCC on thrombin…
View details →Senangkhanikorn S, Morapun N, Samansee A et al. · 2026 · Journal of hospital medicine
Background Timely antibiotic administration is crucial for improving sepsis outcomes, but delays are common and multifactorial. Fever, a key feature of sepsis, is often treated with paracetamol, which may mask the condition and contribute…
View details →Kozlov SV, Agarwal SK, Guerin TM et al. · 2026 · Journal of neuroendocrinology
Metformin is a widely prescribed medication in the management of type 2 diabetes mellitus, and numerous epidemiological studies have indicated an association between metformin use and a reduced risk of certain cancers in diabetic…
View details →Arshad U, Johnson SJ, Fukumori R et al. · 2026 · Journal of dairy science
The objectives of this experiment were to determine the effects of replacing metabolizable Lys from porcine blood meal (PBM) with rumen-protected (RP) Lys (RPL) on lactation performance, ECM/DMI, N use efficiency (NUE; milk N/N intake),…
View details →Bjerregaard-Andersen M, Hostrup PE, Kolnes KJ et al. · 2026 · BMC endocrine disorders
Background A possible association between infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and type 1 diabetes (T1D) development has been reported. Whether SARS-CoV-2 infection affects beta-cell loss in T1D…
View details →Komura S, Hirakawa A, Hirose H et al. · 2026 · The Journal of hand surgery
Purpose This study investigated the influence of preoperative intra-articular steroid injections on surgical outcomes of trapeziectomy with ligament reconstruction and tendon interposition (LRTI) arthroplasty and arthrodesis and aimed to…
View details →Obeidat BS, Al-Khazaleh J, Subih HS · 2026 · Animal Feed Science and Technology.
This study aimed to evaluate the effects of including varying amounts of coffee pulp (COP) in the diet on the growing lambs' meat quality, growth performance, nutrient digestibility, and slaughtering performance. In a random design,…
View details →Keels JN, Babicheva V, McDonald IR et al. · 2026 · Cancers
Background/Objectives : We aimed to test two different visual arrays for helping individuals accurately interpret colorectal cancer risk in Lynch syndrome. We also sought to examine factors associated with intention to share genetic test…
View details →Macêdo AKS, Thompson WA, Santos HB et al. · 2026 · Environmental toxicology
The dispersion of metals in the environment leads to the presence of metal mixtures in impacted ecosystems, but few studies have addressed their impact on early developmental processes in fish. Here, we investigated the effect of metal…
View details →Ogugua UV, Maluleke S, Goszczynska T et al. · 2026 · Potato Res..
The effect of the fall armyworm (FAW) (Spodoptera frugiperda) and the pathogenic bacterium Streptomyces resiliuntiscabiei, in combination or singly, on the morphological and physiological (growth, yield, and gas exchange), and metabolite…
View details →Arias M, Meyer M, Bundschuh M et al. · 2026 · Ecotoxicology and environmental safety
Leaf litter breakdown is a key ecosystem process in streams driven by detritivorous macroinvertebrates and microbial decomposers, but it can be disrupted by anthropogenic stressors. In this context, we examined the effects of the…
View details →Ching ASM, Kim J, Davis C · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior
This preregistered study investigated whether linguistic information can influence low-level visual perception. We argue that many previous studies supporting this view have significant shortcomings. Specifically, these studies conflate…
View details →Sharma M, Srivastava A · 2026 · Annals of internal medicine
Clinical impact ratings GIM/FP/GP: [Formula: see text] Neurology: [Formula: see text] Hematology: [Formula: see text].
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