11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Santoro SL, Alvarado C, Tseng SY et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective In 2022, the U.S. Supreme Court decision on Dobbs v. Jackson Women's Health Organization changed abortion access. We evaluated birth rates of Down syndrome (DS) before and after the Dobbs decision hypothesizing similarity to…
View details →Ukita K, Egami Y, Sugino A et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society
Background Several studies have investigated the efficacy of additional left atrial (LA) roof ablation to pulmonary vein isolation (PVI) using cryoballoon for persistent atrial fibrillation (AF). However, the evidence from randomized…
View details →Aragón-Sánchez J, Víquez-Molina G, Aragón-Hernández J et al. · 2026 · Advances in skin & wound care
Objective The authors hypothesized that prior antibiotic treatment does not reduce culture positivity and that empirical antibiotic therapy in culture-negative cases does not increase the risk of amputation or recurrence in…
View details →Woyke S, Troppmair T, Mair N et al. · 2026 · Journal of the International Society of Sports Nutrition
Background With increasing altitude, the partial pressure of oxygen and oxygen saturation (SpO 2 ) decrease, reducing physical performance. This study investigates whether the nutritional supplement Sanopal® (5-hydroxymethyl-2-furfural and…
View details →García-Rudolph A, Hernández-Pena E, Del Cacho N et al. · 2026 · Revista espanola de enfermedades digestivas
Introduction and aim although generative language models have been extensively studied in the field of digestive diseases, further progress requires addressing underexplored aspects such as linguistic bias, the evaluation of clinical…
View details →Mehdizadeh M, Smith JE, Gill J et al. · 2026 · Plastic and reconstructive surgery. Global open
Background Tranexamic acid (TXA) is commonly used to reduce intraoperative bleeding and complications across surgical specialties. In rhinoplasty, prior studies indicate that TXA may reduce postoperative edema and ecchymosis, but its…
View details →Teixeira PD, Casagrande DR, Rodrigues AC et al. · 2026 · Meat science
Sixteen Nellore and Sixteen Nellore × Angus steers with an initial body weight of 353 kg ±25.3 kg were randomly assigned into 2 feeding groups: whole shelled corn without forage (WSC) or WSC with sugarcane bagasse (WSCB), to evaluate…
View details →Wu X, Chai Q, He J · 2026 · Developmental science
Role ethics suggests that moral obligations arise from the duties associated with one's social roles. Yet, the influence of social roles on children's moral behavior remains unclear. This research addressed this gap by testing whether…
View details →Le Baron M, David G, Ward BA et al. · 2026 · Journal of orthopaedic trauma
Objectives To evaluate whether the use of intraoperative 3D fluoroscopy during acetabular fracture fixation reduces the rate of unplanned returns to the operating room and improves radiographic quality of reduction without increasing…
View details →Bonnot C, Morin E, Da Silva Machado E et al. · 2026 · Plant physiology
Plant small secreted peptides (SSPs) are involved in numerous developmental processes and adaptive plant responses. These include root development, immunity, and symbiotic relationships in herbaceous plants; three processes crucial for…
View details →Brearley FQ · 2026 · American journal of botany
Premise A number of ecologically important tropical trees form symbiotic ectomycorrhizal (EcM) fungal associations including the Dipterocarpaceae, that dominate lowland forests of South-east Asia. Whilst numerous pot-based studies have…
View details →Tanaka S, Kikukawa H, Nakai H et al. · 2026 · Journal of bioscience and bioengineering
Molecular weight of polyhydroxyalkanoate (PHA) is a critical factor governing their physical properties, particularly mechanical strength. It is empirically known that molecular weight of PHA varies depending on factors such as the…
View details →Baek JY, Yu JI, Lee KW et al. · 2026 · Practical radiation oncology
Purpose The role of preoperative radiation therapy (RT) in retroperitoneal sarcoma (RPS) remains controversial across histologic subtypes. Conventional fractionated RT (ConvRT) is the current standard, but hypofractionated RT (HypoRT) is…
View details →Khan MM, Garcia J, Mustamand M et al. · 2026 · Children (Basel, Switzerland)
Background: Effective dental isolation is crucial for successful restorative procedures in pediatric patients; however, its potential impact on patient stress remains underexplored. This investigation comprised two independent pilot…
View details →Mehta S, Huey SL, Ghugre PS et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)
Background and aims Biofortification of staple crops with higher concentrations of micronutrients via traditional breeding methods is a sustainable strategy and can possibly complement fortification and other interventions to target…
View details →Teramoto N, Kobayashi N, Mitsui K et al. · 2026 · The Journal of reproduction and development
Advanced paternal age affects embryonic development and offspring phenotypes. We previously demonstrated that resveratrol prevents age-associated declines in the mitochondrial DNA copy number (mt-cn) and telomere length (TL) in embryos.…
View details →Carrapiso AI, Sánchez-Ordóñez M, Delgado-Adámez J et al. · 2026 · Food science and technology international = Ciencia y tecnologia de los alimentos internacional
The purpose of this study was to investigate for the first time the effect of the enrichment in white or red grape pomace stabilized by high hydrostatic pressure on the characteristics of dry-cured sausages containing additives (75 mg kg…
View details →Hudec J, Prokopova T, Hulkova M et al. · 2026 · Anesthesia and analgesia
Background Anesthetic agents or some pathophysiological conditions can affect transcranial motor evoked potentials (TcMEP) monitoring. However, the influence of depth of anesthesia on TcMEP reproducibility in youth remains unclear due to…
View details →Sastre-Femenia MÀ, Gomis-Font MA, Fernández-Muñoz A et al. · 2026 · Antimicrobial agents and chemotherapy
The triple action of the diazabicyclooctane (DBO) zidebactam (antibacterial activity [penicillin-binding protein 2 {PBP2} inhibitor], β-lactam enhancement [synergy with PBP3 inhibitors], and β-lactamase inhibition [classes A and C])…
View details →Tam J, Wengler K, Yang J et al. · 2026 · Neurourology and urodynamics
Purpose Percutaneous tibial neuromodulation (PTNM) is a standard third line therapy for patients with overactive bladder (OAB). While the therapy has demonstrated efficacy, its exact mechanism of action is unclear. Functional neuroimaging…
View details →Lv Y, Wang F, Shen Y et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Background Accurate lymph node (LN) staging is critical in colorectal cancer (CRC). Carbon nanoparticles (CNPs), used as a tumor localization agent, incidentally stain LNs, creating uncertainty about their utility for improving staging and…
View details →Nielsen S, Fox F, Lam T et al. · 2026 · Addiction (Abingdon, England)
Background and aims Prescription opioid-related harm remains a significant public health concern. This study aimed to evaluate the efficacy of the Opioid Safety Toolkit, a co-designed, interactive online resource, in increasing naloxone…
View details →Yildirim Arslan S, Turanli E, Dinc F · 2026 · The Pediatric infectious disease journal
Background Human rhinovirus is one of the leading causes of pediatric respiratory infections worldwide. Its circulation patterns have shown notable changes in recent years. This study aimed to compare the epidemiologic, clinical and…
View details →Yahata K, Seta K, Osaki K et al. · 2026 · Clinical and experimental nephrology
Background Glucocorticoids have diverse adverse effects, particularly infections that may be severe or opportunistic. Therefore, glucocorticoids are often initiated during hospitalization; however, the optimal glucocorticoid dose at…
View details →Sverdrup LE, Pollestad BM, Sigvaldsen I et al. · 2026 · Chemosphere
Ballast water is essential for ship stability during cargo operations and voyage, but its discharge can introduce invasive aquatic species to new environments. To mitigate this risk, ballast water is commonly treated with oxidants such as…
View details →Ostertag-Hill CA, Cummings OW, Renaud EJ · 2026 · Rhode Island medical journal (2013)
Objective The diagnostic evaluation, antibiotic treatment, and type and timing of surgical intervention for pediatric patients with complicated pneumonia is not standardized and may lead to increased length of stay, more radiation…
View details →Lantermino A, Lapuente C, Blanco PG et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
The aim of this study was to describe and compare the effect of different lighting protocols on sexual cyclicity and serum melatonin in domestic female cats. Additionally, anti-Müllerian hormone (AMH) concentrations and ultrasound or…
View details →Barron CR, Ramineni M, Finkelman BS et al. · 2026 · Human pathology
Objectives Women who carry a germline mutation in BRCA1 have an increased lifetime risk of developing breast cancer (BC). Prior Next-Generation Sequencing (NGS) studies on BCs from patients with germline BRCA1 mutations (gBRCA1) were…
View details →Burdette ER, Pelletier A, Freret TS et al. · 2026 · American journal of perinatology
This study aimed to evaluate inpatient COVID-19 vaccine uptake among pregnant and postpartum patients.Retrospective cohort study of patients admitted to the antepartum and postpartum services of two academic hospitals between April 2021…
View details →Bracone F, Di Castelnuovo A, Costanzo S et al. · 2026 · Clinical nutrition (Edinburgh, Scotland)
Background and aims Mediterranean diet (MD) has been associated with a reduced risk of depressive symptoms, while high intake of ultra-processed foods (UPFs) has been linked to poorer mental health. However, the long-term combined effects…
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