11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Casey ER, Uritsky T, Soyfer L et al. · 2026 · Substance use & addiction journal
Background Hospitals increasingly start methadone treatment for opioid use disorder (OUD). Rapid methadone titration has been described in hospitals with addiction consult teams; however, most hospitals lack these specialty services. We…
View details →Tannuri ACA, Abe Takahasi BN, de Almeida Estrambk G et al. · 2026 · Journal of pediatric surgery
Background Esophageal atresia (EA) is frequently associated with congenital heart disease (CHD) and chromosomal anomalies, mainly Down syndrome (DS). While these conditions affect outcomes following primary repair, their specific impact on…
View details →Muñoz-Tebar N, Lucas-González R, Muñoz-Bas C et al. · 2026 · Food chemistry
This study investigates the use of quinoa oil emulsion as a novel plant-based ingredient to improve the nutritional quality of fresh goat cheese. Quinoa oil emulsions (3 and 6 g/L) were characterized and incorporated in fresh cheese. The…
View details →Cui B, Liu Y, Wu X et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
The objective of this study was to evaluate the effects of exogenous GnRH administration at the beginning of estrus synchronisation in mares during the spring transitional period. Estrus was synchronised using a progesterone releasing…
View details →Mauvieux B, Montardy Q, Remilly M et al. · 2026 · Wilderness & environmental medicine
Off-grid low-tech living is increasingly proposed for arid environments, yet longitudinal field data documenting health, nutrition, and rest-activity organization under real-world conditions remain scarce. Our objective was to describe…
View details →Cheever K, Kalvesmaki A, Swan AA et al. · 2026 · Brain injury
Background This study aimed to explore what treatments were sought by post-9/11 Veterans with and without a formal diagnosis related to their long-term dizziness following completion of a Comprehensive Traumatic Brain Injury Evaluation…
View details →Lee YJ, Kim J, Yu DH et al. · 2026 · Kidney research and clinical practice
Background Tegoprazan, a potassium-competitive acid blocker used in South Korea since 2018, was examined in this study for its potential association with death or progression to end-stage kidney disease (ESKD) among patients with stage 3…
View details →Luo Y, Liu A, Hu B et al. · 2026 · Forest Ecology and Management.
Temporal demographic compensation (TDC), defined as negative temporal covariance between demographic vital rates (e.g., growth, survival, reproduction), is expected to buffer variability in population growth and promote long-term…
View details →Li X, An K, Sun Z et al. · 2026 · Biofouling
'Yellow water' issues frequently occur in drinking water supply systems on university campuses, primarily caused by the resuspension of loose sediments within pipelines, which may pose high potential microbiological risks. In order to…
View details →Shehu E, Pieper D, Albrecht HC et al. · 2026 · JBI evidence implementation
Introduction Pre-operative stoma site marking is a strongly recommended practice for preventing complications and improving the health-related quality of life of intestinal stoma patients. Despite its benefits, this practice is not…
View details →Richard NA, Claydon VE, Koehle MS et al. · 2026 · Medicine and science in sports and exercise
Introduction Female athletes, or those in arduous occupations, lack objective guidance on effective and safe rigorous training postpartum. We examined the effectiveness and tolerability of early postpartum sprint interval training (SIT) in…
View details →Cuttance EL, Mason WA, Jamieson P et al. · 2026 · New Zealand veterinary journal
Aims To evaluate, in a sample of cows on a New Zealand dairy farm, whether different methods of oral supplementation with zinc were effective in raising serum Zn concentrations ≥ 18 μmol/L, the target threshold for protection from facial…
View details →Chen W, Zhou Y, Wang M et al. · 2026 · Acta psychologica
This study aimed to explore the impact of calligraphy training on the emotional well-being of college students，as well as the mediating roles of state mindfulness and rumination in this relationship, using a cross-sectional design (N =…
View details →Wang Y, Song Z, Guo Q et al. · 2026 · Environmental science & technology
Mounting evidence confirms that microplastics (MPs) pose ecological risks. Despite the environmental relevance of aged MPs under warming, little is known about their particle versus leachate toxicity. Here, we mechanistically quantify…
View details →Lerche CM, Granborg JR, Al-Chaer RN et al. · 2025 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Glyphosate (GLY) is the most widely used pesticide in the world. Agricultural workers are exposed to GLY via ingestion and skin contact. GLY may generate epigenetic changes that might be carcinogenic. However, whether GLY is carcinogenic…
View details →Suksathien Y, Suarjui J, Tippimanchai T et al. · 2026 · International orthopaedics
Purpose Intraoperative calcar fracture (IOCF) can compromise initial stability, leading to stem subsidence and instability. We aimed to compare 2-year complications and revision rates between patients who sustained IOCF and matched…
View details →Chesney KM, McAbee JH, Balu A et al. · 2026 · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Purpose Tethered cord release (TCR) is typically well tolerated in children, but cerebrospinal fluid (CSF) leaks can occur postoperatively, with rates as high as 33%. The aim of this study was to determine perioperative risk factors…
View details →Gorsagun S, Pruksanusak N, Geater AF · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective To compare pregnancy outcomes between early and standard treatment of gestational diabetes mellitus (GDM) diagnosed using the Carpenter-Coustan criteria and to assess the impact of applying the International Association of…
View details →Dai H, Wang Y, Shan F et al. · 2026 · BMC gastroenterology
Background Neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (nCRT) are increasingly used to treat adenocarcinoma of the esophagogastric junction (AEG). However, there is insufficient clinical evidence to compare surgical…
View details →Sato M, Torii K, Hiramatsu Y et al. · 2026 · Surgical endoscopy
Background Safe establishment of pneumoperitoneum is essential in laparoscopic surgery because most access-related injuries occur during peritoneal entry. In Veress needle procedures, this step is performed blindly, and conventional…
View details →Muto T, Machida S, Imaizumi S et al. · 2026 · Journal of ophthalmology
Purpose To determine the prevalence and clinical characteristics of retinal artery occlusion (RAO), including branch RAO (BRAO) and central RAO (CRAO), among new patients before and after the declaration of a state of emergency due to…
View details →Maschoreck LG, Stokholm L, Pedersen FN et al. · 2026 · Acta ophthalmologica
Purpose Diabetic retinopathy (DR) is a frequent long-term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly…
View details →Elhoweris AE, Sullivan M, Norton W et al. · 2026 · Transplantation proceedings
Background Urinary tract infections (UTIs) are the most common infection following kidney transplantation. However, the natural history of UTIs is incompletely understood, as is the impact of UTIs on patient outcomes. Methods A…
View details →Wang N, Xu T, Li H et al. · 2026 · International journal of radiation oncology, biology, physics
Purpose To characterize the long-term endoscopic natural history of chronic radiation proctitis (CRP) and identify predictors of severe lesions in patients with locally advanced rectal cancer from the STELLAR study (NCT02533271) . Methods…
View details →Sano Y, Yagi N, Ito Y et al. · 2026 · Digestive diseases and sciences
Background and aims The role of 5-aminosalicylates (5-ASA) in maintaining remission in patients with ulcerative colitis (UC) receiving advanced therapy remains controversial. This study evaluated the safety and feasibility of 5-ASA…
View details →Smith DC, Gemkow JW, Shiferaw BA et al. · 2026 · Journal of midwifery & women's health
Introduction Use of labor induction has increased rapidly for medical and nonmedical reasons, raising questions about its impact on cesarean birth rates. With growing incidence of elective induction of labor (IOL) at 39 weeks, uncertainty…
View details →Koskinen JP, Harju M, Välimäki J · 2026 · Acta ophthalmologica
Purpose To evaluate changes in corneal tomography, pachymetry and endothelial cell density (ECD) following Paul Glaucoma Implant (PGI) surgery. Methods Seventy-three patients were prospectively examined. Repeated measures anova was used to…
View details →Wang Q, Kimura Y, Oba J et al. · 2026 · European journal of pediatrics
Routine echocardiography at one month after diagnosis is the current standard for screening coronary artery abnormalities (CAA), a major complication of Kawasaki disease. The study aimed to develop and validate models to predict CAA and…
View details →Jenkins TL, Darden K, Pourdeyhimi B et al. · 2026 · Journal of biomechanics
Synthetic polymer scaffolds with aligned fibers permit engineered tendon development and the formation of an aligned, collagen rich matrix. However, many tissue engineered constructs cannot withstand physiologically relevant loads. Both…
View details →Mohammadi S, Cunnane ME, Juliano AF et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Four-dimensional CT (4D-CT) is a key imaging modality for preoperative localization of parathyroid adenomas in primary hyperparathyroidism. Ultrasound (US) is frequently added with the assumption that it enhances…
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