11,322 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ma Z, Cao W, Zhang J et al. · 2026 · Neuroreport
Background γ-Aminobutyric acid (GABA) is essential for the central sedative/hypnotic actions of ethanol. The tuberomammillary nucleus (TMN), the exclusive source of forebrain histaminergic innervation, functions as the principal arousal…
View details →Sugawara K, Yagi K, Yajima S et al. · 2026 · International journal of clinical oncology
Purpose We aimed to evaluate the outcomes of transmediastinal esophagectomy (TME) for esophagogastric junction cancer (EGJC) patients. Methods We retrospectively reviewed patients who underwent TME for EGJC (Siewert Type II) between 2018…
View details →Li Y, Chen W, Hill R et al. · 2026 · European clinical respiratory journal
Asthma is a chronic respiratory condition that can be managed using Single Maintenance and Reliever Therapy (SMART) or traditional therapy with inhaled corticosteroid (ICS)-long-acting beta-agonist (LABA) for maintenance and short-acting…
View details →Cosenza M, Fabbri M, Pizzini B et al. · 2026 · Journal of gambling studies
Adolescence represents a critical developmental period for the emergence of maladaptive gambling behaviors, including loss chasing, a key marker of gambling-related harm. The present study provides the first behavioral examination of the…
View details →Vidon M, Wang X, Costes L et al. · 2026 · Clinics and research in hepatology and gastroenterology
Background and study aims Educational interventions have been proposed to improve adherence to bowel preparation instructions. We evaluated whether adding a short instructional video to standard written and oral information improves bowel…
View details →Ahmed ME, Mahjoub SMAH, Adam SIY · 2026 · Tropical animal health and production
This study evaluated the effects of partially replacing groundnut cake with soaked chickpea (Cicer arietinum L.) seeds, with or without enzyme supplementation, on growth performance, carcass traits, serum biochemical indices, and…
View details →Thapa K, R Iyer A, A Cruz-Gonzalez M et al. · 2026 · Journal of racial and ethnic health disparities
Background Refugees often experience disruptions in social networks after resettlement. This study examined associations between bonding (within-group) and bridging (across-group) social capital and self-rated health among resettled U.S.…
View details →Mathiesen KK, Rasmussen JH, Channir H et al. · 2026 · Acta oto-laryngologica
Background Cancer of unknown primary (CUP) is diagnostically challenging. Diagnostic strategy remains controversial. Aim The aim of this retrospective study was to evaluate the diagnostic value of FDG-PET/CT and MRI in detecting primary…
View details →Abdulameer HS, Zarrinkavyani K, Fathi M et al. · 2026 · Poultry science
Transport of day-old chicks is a major concern in the poultry industry, as it induces stress that can impair performance and health. This study investigated whether xylazine, an alpha-2 adrenergic agonist that reduces metabolic rate, could…
View details →Rutkūnas V, Kubilius A, Akulauskas M et al. · 2026 · Journal of dentistry
Objectives This in vitro study evaluated the accuracy of digital impressions for full-arch implantsupported restorations by assessing scan body (SB) positional accuracy and inter-arch registration under different intraoral scanners (IOS)…
View details →Miyahara Y, Nagel R, Frieß W · 2026 · Journal of pharmaceutical sciences
Dissolved oxygen (DO) has been proposed to influence protein stability during freeze-thaw (F/T) processing, yet its direct impact remains unclear. This study evaluated whether DO levels or vacuum degassing affect the stability of human…
View details →Rawal R, Thyagarajan A, Sahu RP · 2026 · Medical sciences (Basel, Switzerland)
Background/objectives Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality, driven by invasive behavior and frequent resistance to systemic therapies. Epidermal growth factor receptor tyrosine kinase inhibitors…
View details →Ikawa D, Miura A, Miyata K et al. · 2026 · Scientific reports
Manual support and interpersonal interaction can enhance postural stability during upright standing, yet it remains unclear how tactile and visual interactions influence the temporal organization of postural control. We used a 2 × 2…
View details →Yin Y, Li C, Feng Y et al. · 2026 · Veterinary sciences
This study investigated the effects of composite postbiotic preparation on the growth performance, immune function, and microbiota composition of Nubian black goats. Thirty healthy Nubian black goats with similar body weights were randomly…
View details →Barkan R, Goren I, Fischman M et al. · 2026 · Digestive diseases and sciences
Background Nurses play a key role in inflammatory bowel disease (IBD) management. This randomized controlled trial evaluated intensive nurse-led program in patients with IBD starting advanced therapy. Methods Patients were randomized (1:1)…
View details →Bin Ghouth S, Cigdem O, Mazzoli V · 2026 · Journal of magnetic resonance imaging : JMRI
Background Muscle mass decline, associated with strength decline, is a hallmark of aging. Yet, strength decline greatly exceeds mass decline. This indicates that aspects of muscle quality and architecture-not reflected by mass-also…
View details →Alghamdi MA, Almasaad JM, Ahmed ME et al. · 2026 · Anatomical sciences education
The choice of instructional language in medical education continues to be debated across non-English-speaking nations. In Saudi Arabia, medical schools use English as the medium of instruction, which may challenge students who previously…
View details →Huber AL, Picavet PP, Hamon M et al. · 2026 · American journal of veterinary research
Objective To measure hip flexion, abduction, and internal rotation in a static standing position with the limb maintained with a traditional Ehmer sling (TES), compare these with a commercially available vest-based sling (VBS), and…
View details →Erdem G, Kavak Akelma F, Nalbant B et al. · 2026 · Acupuncture in medicine : journal of the British Medical Acupuncture Society
Objective Nausea, vomiting and pain are common postoperative complications. The aim of this study was to evaluate the effects of ondansetron combined with acupuncture at bilateral PC6 during the intraoperative period on the incidence of…
View details →Østergaard AM, Rosenbæk JB, Ejlersen JA et al. · 2026 · Physiological reports
Inorganic nitrate may lower blood pressure (BP) and enhance natriuresis through nitric oxide (NO) mediated mechanisms. Studies have found inconsistent effects of NO on sodium excretion. Nitric oxide synthase (NOS) inhibition suggests…
View details →Phan T, Datt P, Zhao L et al. · 2026 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose Rheumatoid arthritis (RA) is a chronic, autoimmune joint disorder necessitating the use of complex, specialty medications. Health-system specialty pharmacies (HSSPs) operate under closed-loop models that have been shown to minimize…
View details →Júnior FC, Santos WRD, Cordeiro Feitosa R et al. · 2026 · Research quarterly for exercise and sport
Taurine (TAU) is a conditionally essential amino acid whose consumption has recently increased, particularly among young people, through supplements and energy drinks. It has potential beneficial effects on physical performance; however,…
View details →Haskic A, Hadziabdic N, Miron RJ · 2026 · International journal of oral and maxillofacial surgery
Postoperative sequelae such as pain, swelling, and trismus are common following mandibular third molar surgery. This single-blind controlled trial was performed to evaluate the effects of two newer platelet-rich fibrin (PRF) formulations,…
View details →Choo LY, Zheng W, Wen S et al. · 2026 · Journal of the American Pharmacists Association : JAPhA
Background Patients with opioid use disorder encounter challenges obtaining buprenorphine (BUP) at pharmacies, increasing their risk of treatment non-adherence and illicit drug use. Objectives The purpose of this quality improvement (QI)…
View details →DiBona ER, Elliott J, Labeille RO et al. · 2026 · Aquatic toxicology (Amsterdam, Netherlands)
Per- and polyfluoroalkyl substances (PFAS) are persistent contaminants with immunotoxic potential, yet impacts on immune development remain poorly defined. We examined effects of developmental PFAS exposure on host resistance and…
View details →Gok A, Kavakli AS, Sugur T et al. · 2026 · Expert review of anti-infective therapy
Background This study aimed to assess culture positivity rates and the microbiological profile of intensive care unit (ICU)-acquired superinfections in patients with severe COVID-19 pneumonia treated with pulse-dose methylprednisolone,…
View details →O'Connor J, Ladonice S, Backes B et al. · 2026 · Violence and victims
This study compares the mental health outcomes of survivors of intimate partner violence (IPV) whose primary language is not English with those of survivors whose primary language is English. A total of 126 IPV survivors were recruited for…
View details →Stephansen RB, Lassen J, Lund MS et al. · 2026 · Journal of dairy science
This study aimed to quantify the effect of the methane-mitigating feed additive 3-NOP on genetic parameters and potential genotype-by-environment (G × E) interaction for gas emission traits, i.e., methane (CH 4 ) and, carbon dioxide (CO 2…
View details →Lu B, Liu X, Zhang P et al. · 2026 · Traffic injury prevention
Objective Driver workload is a safety-relevant factor that may contribute to impaired driving performance and an increased risk of traffic injury. Cabin temperature is a modifiable in-vehicle environmental condition, but its influence on…
View details →Yazici Akbiyik S, Yikici Col C, Bakir E · 2026 · Quintessence international (Berlin, Germany : 1985)
Objectives This study evaluated the effect of polymerization mode on dentin bond strength of universal adhesives applied using etch-and-rinse (ER) and self-etch (SE) strategies, before and after thermocycling. Method and materials A total…
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