11,319 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Aydilek A, Erdem Y · 2026 · BMC surgery
Background Posterior malleolar fractures accompanying trimalleolar ankle injuries may compromise joint stability and lead to long-term functional impairment. However, the impact of posterior malleolar fragment (PMF) size on postoperative…
View details →Urashima T, Yabuno T, Imanishi K et al. · 2026 · Surgical endoscopy
Background Few studies have directly compared the incidence of primary postoperative ileus (primary POI) between robotic surgery (RS) and laparoscopic surgery (LS) for rectal resection. Methods This retrospective cohort study included…
View details →Fujii S, Hirai S, Fujita K et al. · 2026 · Neurologia medico-chirurgica
Flow diverter braid deformation is occasionally observed after flow diverter placement. However, the frequency and clinical significance of flow diverter braid deformation in non-drawn filled tube wire devices remain unclear. This…
View details →Ntaka KL, Mpanya D, Adamu UG et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Background The radial artery is the preferred access for performing diagnostic coronary angiograms (DCA). However, data on the safety and efficacy of radial compared to femoral access in low- and middle-income countries is limited. Aims…
View details →Ižarik Verešpejová A, Grendár M, Kertys M et al. · 2026 · Biomolecules
Bile acids (BA) are increasingly recognized as signaling molecules involved in metabolic regulation and inflammatory processes, both of which are relevant to Parkinson's disease (PD). However, their role in PD and disease progression…
View details →Gucluer Kocaoglu MN, Kahraman H, Nayman S et al. · 2026 · BMC infectious diseases
Background Staphylococcus aureus bacteremia (SAB) is associated with substantial short-term mortality, but the relative contributions of methicillin resistance, treatment adequacy, and host-related factors to outcome remain unclear. This…
View details →Sun J, Xiong Y, Qiu J et al. · 2026 · Annals of surgical oncology
Background Locally advanced thymic epithelial tumors (TETs) may extend into the adjacent brachiocephalic vein (BCV), creating major technical challenges for resection. While BCV reconstruction is traditionally considered after tumor…
View details →Lis M, Miłuch T, Krupa R et al. · 2026 · Scientific reports
Major depressive disorder (MDD) frequently co-occurs with obesity, suggesting shared neuroendocrine mechanisms. Ghrelin, a hormone involved in appetite regulation, stress response, and reward processing, has been proposed as a biological…
View details →Chao M, Wang Y, Gu L · 2026 · The Psychiatric quarterly
Short video platforms like TikTok are increasingly popular among adolescents. The study investigated the correlation between adolescent short video use (SVU) patterns and psychological well-being. Using a sample of 2,344 Chinese junior and…
View details →Oteir A, Husein M, Alhawatmeh H et al. · 2026 · International emergency nursing
Background Spinal motion restriction (SMR) remains a fundamental component of trauma care, yet its routine application has been increasingly questioned. Evidence supporting selective SMR has grown; however, limited data exist on the…
View details →Suraju MO, Longbottom B, Peteson JA et al. · 2026 · American journal of surgery
Introduction Factors influencing mortality among pancreatic ductal adenocarcinoma (PDAC) patients who achieve pathologic complete response (pCR) following neoadjuvant therapy have not been previously well studied. Methods Adult PDAC…
View details →Kate A, Wannapanich T, Mandell J et al. · 2026 · American journal of ophthalmology
Purpose To compare clinical characteristics, microbiological profiles, treatment strategies, and outcomes between contact lens-associated (CL) and non-contact lens-associated (non-CL) fungal keratitis. Design Retrospective, comparative…
View details →Fresa R, Napoli A, Bitterman O · 2026 · Acta diabetologica
Introduction the use of Automated Insulin Delivery (AID) systems has increased in pregnant women with type 1 diabetes (DM1). To date, little data exist regarding glucose control and insulin modifications with AID in automode during…
View details →Lee YJ, Moon SW · 2026 · Journal of clinical medicine
Background/Objectives : In February 2024, a nationwide medical crisis in South Korea caused a massive withdrawal of resident physicians. We described changes in patient characteristics and early clinical outcomes among emergency department…
View details →Solazzo EM, Jarabana SG, Baird J et al. · 2026 · Rhode Island medical journal (2013)
Objectives Pre-hospital emergency care depends on reliable infrastructure. On December 11, 2023, the westbound span of the Washington Bridge connecting eastern and western Rhode Island (RI) closed emergently due to structural issues. This…
View details →Shapiro G, Kamm JM, Wintrode M et al. · 2026 · The Clinical neuropsychologist
Objective: Evaluations for attention-deficit/hyperactivity disorder (ADHD) in adulthood typically incorporate both self-report questionnaires and performance-based cognitive testing. Extant research has demonstrated weak or absent…
View details →Majewski MS, Hanć A, Krajewska-Włodarczyk M et al. · 2026 · Nutrients
Background/Objectives : Red beetroot ( Beta vulgaris L.) is recognized for its antioxidant, anti-inflammatory, and metabolic properties. This study evaluated the effects of two beetroot cultivars ( Boldor and Wodan ) on blood serum…
View details →Wen YP, Brauer ER, Choi S et al. · 2026 · BMC public health
Background Cancer survivors are twice as likely to experience psychological distress, with racial and ethnic minorities reporting higher distress and healthcare needs compared to non-Hispanic White Americans. However, this group is more…
View details →Maeda K, Funahashi H, Tokutake K et al. · 2026 · International orthopaedics
Purpose This study aimed to evaluate postoperative outcomes, including clinical results, radiological assessments, and complications, in patients over 50 years old with nondisplaced femoral neck fractures (Garden classification I-II)…
View details →Liu Y, Liu L, Wang J et al. · 2026 · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Objective Nephrotoxicity of bisphosphonates limits their utility in the management of severe hypercalcemia among patients with primary hyperparathyroidism (PHPT) and impaired renal function. It remains unclear whether denosumab is an…
View details →Zheng J, Chen M, Fu J · 2026 · BMC oral health
Background This retrospective cohort study evaluated a Locator-bilateral segmental bar concept (LBSB) for maxillary implant-supported overdentures and compared it with a conventional rigid bar concept (CRB) in terms of implant survival,…
View details →Gentile T, Vanacore S, Caputo M et al. · 2026 · Children (Basel, Switzerland)
Background/objectives Dental anxiety represents a major challenge in paediatric dentistry and is a frequent cause of non-cooperative behaviour during dental treatment. Nitrous oxide/oxygen inhalation conscious sedation is widely used to…
View details →Aucoin AA, Zhidkov V, Legere RM et al. · 2026 · American journal of veterinary research
Objective To characterize age-related trajectories of the relative concentrations of anti-virulence-associated protein A (VapA) immunoglobulin (Ig)-G1, IgG3/5, IgG4/7, and IgA in serum and bronchoalveolar lavage fluid (BALF) as indicators…
View details →Wang X, Li W, Wang F et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses
Purpose The objective of this study was to evaluate whether combining pain neuroscience education (PNE) with progressive muscle relaxation (PMR) could reduce acute pain after thoracoscopic lung resection, alleviate psychological distress,…
View details →Chen L, Xu D, Hou L · 2026 · Medical principles and practice : international journal of the Kuwait University, Health Science Centre
Background/objective Prone percutaneous nephrolithotomy (PCNL) is commonly performed under general anesthesia (GA); however, increasing evidence supports the feasibility of PCNL under spinal anesthesia (SA). This study presents our…
View details →Mao W, Lu N · 2026 · Journal of investigative surgery : the official journal of the Academy of Surgical Research
Objective To evaluate short-term clinical outcomes, surgeon-reported fatigue, and staff user experience associated with a multifunctional operative support arm in reproductive laparoscopic surgery. Design Single-center, parallel-group…
View details →Lee JR, Choi H, Eum D et al. · 2026 · Anesthesia and pain medicine
Background Intravenous (IV) administration of dexamethasone has been reported to prolong the analgesic duration of a caudal block. The aim of this study was to compare the analgesic effects of IV low-dose and high-dose dexamethasone in…
View details →Bouali B, Rezzaoui A, Hamzeh-Cognasse H et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
Background Pathogen reduction treatment (PRT) of platelet concentrates (PC) is one of the most recent advances in improving blood safety and lowering the risk of transfusion-transmitted diseases. The characteristics of PR-treated PC differ…
View details →Igasaki M, Furusawa A, Kunishi M et al. · 2026 · The journal of obstetrics and gynaecology research
Aim This study aimed to evaluate the efficacy of local treatment in patients with sporadic recurrent endometrial cancer. Methods We retrospectively reviewed patients who received treatment for first recurrence of endometrial cancer at our…
View details →Anundson J, Lee L, Bae S et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Introduction Lumbar fusion alters spinal biomechanics and may increase hip loading, especially with long-segment constructs. We used a large administrative database to evaluate hip fracture risk after lumbar fusion and assess whether…
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