Negative / Null Result ReportOpen accessMedicine
Tavoly M, Jørgensen CT, Sandblad KG et al. · 2026 · Research and practice in thrombosis and haemostasis
Background It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited. Objectives This study…
View details →Negative / Null Result ReportOpen accessMedicine
Serrari M, Bianchi L, Tré-Hardy M et al. · 2026 · Microorganisms
Antenatal screening for Group B Streptococcus (GBS) does not always reflect intrapartum colonisation status, and rapid molecular point-of-care tests (POCT) have been developed to enable real-time detection during labour. This prospective…
View details →Negative / Null Result ReportMedicine
McCulloch H, Lohr PA · 2026 · Obstetrics and gynecology
Objective To assess the accuracy of using the last menstrual period (LMP) date for determining gestational age, compared with ultrasonography, among patients aged younger than 16 years at British Pregnancy Advisory Service (BPAS), a large…
View details →Negative / Null Result ReportMedicine
Yi J, Bi K, Shen M et al. · 2026 · Academic radiology
Objectives This study aimed to develop a post-procedural predictive model for assessing the risk of false-negative results in ultrasound-guided percutaneous transthoracic needle lung biopsy (US-PTLB). Material and methods Two prospective…
View details →Negative / Null Result ReportOpen accessMedicine
Ma JY, Jiang W, Cheng B et al. · 2026 · Endoscopic ultrasound
Background and objectives Repeated EUS-guided fine-needle aspiration/biopsy (rEUS-FNA/B) is recommended in solid pancreatic lesions (SPLs) with inconclusive initial results. However, even rEUS-FNA/B cannot completely eliminate false…
View details →Negative / Null Result ReportMedicine
Tsai CT, Liang SY, Lai CH et al. · 2026 · Infection
Purpose Non-induced sputum galactomannan (GM) testing is increasingly used in routine evaluation of suspected invasive pulmonary aspergillosis (IPA), yet its real-world performance and the clinical implications of negative results remain…
View details →Negative / Null Result ReportMedicine
Anettová L, Jaume-Ramis S, Paredes-Esquivel C et al. · 2026 · Journal of helminthology
Pooling of gastropod samples is frequently used in surveys of the neurotropic nematode Angiostrongylus cantonensis to reduce cost and processing time. Here we highlight a potential limitation of this technique using the snail Theba pisana…
View details →Negative / Null Result ReportMedicine
Andronache J, Cichna-Markl M, Dobrovolny S et al. · 2026 · NPJ science of food
Food fraud through species substitution has been reported for edible gastropods, particularly in processed products where morphological identification is not feasible. DNA-based methods have been used to identify gastropod species in food…
View details →Negative / Null Result ReportOpen accessMedicine
Otwell T, Knight B, Coryell M et al. · 2025 · Frontiers in cellular and infection microbiology
Molecular diagnostic assays are critical tools to test, diagnose and treat infectious and other diseases. For example, PCR test results have been extremely valuable during the COVID-19 pandemic, not only to provide appropriate health care…
View details →Negative / Null Result ReportMedicine
Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →Negative / Null Result ReportOpen accessMedicine
Khoshakhlagh M, Dehghani T, Alizadeh A et al. · 2026 · Iranian journal of pathology
Background & objective Real-time PCR is widely used to detect SARS-CoV-2, the virus responsible for COVID-19, but false-negative results can occur even with internal controls. This study aimed to investigate the impact of using alternative…
View details →Negative / Null Result ReportOpen accessMedicine
Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →Negative / Null Result ReportMedicine
Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →Negative / Null Result ReportMedicine
Costa M, Rodrigues P, Araújo B et al. · 2026 · Diagnostic microbiology and infectious disease
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity.…
View details →Negative / Null Result ReportMedicine
Li QX, Luo LZ · 2026 · BMC infectious diseases
Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are rare. Atypical clinical manifestations and the need for precise microbiological identification often result in misdiagnosis and underdiagnosis. Case…
View details →Negative / Null Result ReportOpen accessMedicine
Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →Negative / Null Result ReportMedicine
Connolly M, McClelland L, Tannorella P et al. · 2026 · Prenatal diagnosis
Objective Prenatal genetic testing for imprinting disorders is rarely requested with the exception of Beckwith-Wiedemann syndrome (BWS) which is associated with specific ultrasound findings (e.g., placental mesenchymal dysplasia,…
View details →Negative / Null Result ReportMedicine
Ailun G, Li Y, Zhang D et al. · 2026 · Journal of medical case reports
Ovarian carcinosarcoma, also known as malignant mixed Müllerian tumor (MMMT), is a rare and highly aggressive gynecologic malignancy characterized by the presence of both epithelial and mesenchymal components. It predominantly affects…
View details →Negative / Null Result ReportMedicine
Schroeder TH, Eliwi Alsaffan M, Stäudle H et al. · 2026 · Journal of clinical medicine
Background: Blood cultures often yield negative results in critically ill patients, particularly after antimicrobial therapy has started. Plasma metagenomic next-generation sequencing enables culture-independent pathogen detection, but its…
View details →Negative / Null Result ReportMedicine
Rhodes JM · 2026 · The British journal of nutrition
It is widely known that the short chain fatty acid (SFA) butyrate, generated mainly through fermentation of dietary fibre by anaerobic bacteria, has beneficial effects on health. Less widely known is that butyrate, at the concentration…
View details →Negative / Null Result ReportOpen accessMedicine
Wang H, Ardura MI, Oyeniran SJ et al. · 2026 · ASM case reports
Background Cytomegalovirus (CMV) continues to be a significant cause of morbidity and mortality in immunocompromised patients. Nucleic acid amplification tests (NAATs) are the preferred method for both diagnosing CMV infection and…
View details →Negative / Null Result ReportMedicine
Hinoshita M, Maeda Y, Kawai A et al. · 2026 · The Journal of toxicological sciences
The modified electron spin resonance (ESR)-based photosafety test (ESR-PT) is a non-animal prediction test using ESR spectroscopy that is applicable to hydrophobic and colored chemicals and the results show high concordance with existing…
View details →Negative / Null Result ReportMedicine
Christopher-Stine L · 2026 · The Journal of rheumatology
Although statin-induced muscle toxicity was recognized, a subset of patients presented with severe, persistent necrotizing myopathy despite statin withdrawal. Recognized initially through the serendipitous aggregation of cases in the…
View details →Negative / Null Result ReportOpen accessMedicine
Alvarez AM, Vega M, Valencia-Shelton F et al. · 2026 · Cureus
Background The evaluation of neonatal herpes simplex virus (HSV) includes HSV culture and/or polymerase chain reaction (PCR) of different surfaces, cerebrospinal fluid (CSF), and blood. However, the impact of blood HSV PCR for the…
View details →Negative / Null Result ReportMedicine
Dellbrügge F, Schaumann N, Kruppa M et al. · 2026 · Pneumologie (Stuttgart, Germany)
Abstract We present the case of a 39-year-old Indian female patient diagnosed with tuberculous mastitis and lymph node tuberculosis. The patient had a history of tuberculosis infection treatment as a newborn. She initially presented with…
View details →Negative / Null Result ReportMedicine
Li X, Huang Y, Hao J et al. · 2026 · Current HIV research
Background Married Men who have Sex with Men (MSM) constitute a bridge population for HIV diffusion into low-risk groups, with spousal non-disclosure rates exceeding 60% in China. It will increase the risk of secondary transmission within…
View details →Negative / Null Result ReportMedicine
Tsang SM, Merino Gutierrez V, Yu J et al. · 2026 · Veterinary sciences
Canine babesiosis caused by Babesia gibsoni is prevalent in Hong Kong. While molecular diagnosis via PCR is highly sensitive, it typically requires reference laboratory access, delaying clinical decisions. This study evaluated the…
View details →Negative / Null Result ReportMedicine
Hijaze E, Razi T, Arbel R et al. · 2026 · Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
Objective To evaluate the diagnostic performance of BioPlex 2200 multiplex immunoassay (BI) for detecting antinuclear antibodies (ANA), compared with the gold standard, the indirect immunofluorescence assay (IIF), as a screening…
View details →Negative / Null Result ReportMedicine
Tri PM, Hung NT, Liet DH et al. · 2026 · Emergency radiology
Purpose To assess the diagnostic performance of computed tomography (CT) for predicting main pancreatic duct injury in surgically explored patients with distal pancreatic trauma. Methods We conducted a prospective single-center diagnostic…
View details →Negative / Null Result ReportMedicine
Wei XT, Zhu LY, Wu YL et al. · 2026 · Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Objective: To evaluate the screening performance and related factors of ultrasound for hepatic steatosis in community-based elderly populations using controlled attenuation parameter (CAP) measured by transient elastography as the…
View details →