11,317 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Friehs MA, Brauner L, Frings C · 2021 · Experimental brain research
Stopping an already initiated action is crucial for human everyday behavior and empirical evidence points toward the prefrontal cortex playing a key role in response inhibition. Two regions that have been consistently implicated in…
View details →Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports
Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…
View details →Liu S, Nolin DA, Kitts JA · 2024 · Social networks
Recent studies have found order effects in social network data collection, where later names on a roster receive fewer nominations. Some thus argue for randomizing name orders or sampling peer names for survey rosters. We model order…
View details →Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open
Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…
View details →Shi P, Wei G, Li Z et al. · 2026 · Brain and behavior
Background Toxoplasma gondii (T. gondii) is a ubiquitous protozoan parasite capable of establishing lifelong latent infections in the central nervous system. Previous epidemiological studies have suggested a potential association between…
View details →Pott J, Mason AM, Salo V et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer survival (BCS), suggesting PCSK9 inhibition as an…
View details →Liu B, Alexopoulou ZS, van Ede F · 2024 · Communications psychology
Brain circuitry that controls where we look also contributes to attentional selection of visual contents outside current fixation, or content within the spatial layout of working memory. A behavioural manifestation of this contribution…
View details →Hornsey MJ, Spence JL, Chapman CM · 2026 · Nature communications
Effective altruists argue that charitable giving is over-influenced by empathic responses and should instead be guided by cost-benefit analyses about the effectiveness of giving. To provide insight into the extent to which empathy and…
View details →Wilcockson TDW, Roy S, Crawford TJ · 2025 · Perception
Functional Cognitive Disorder ("FCD") is a type of Functional Neurological Disorder characterised by subjective cognitive complaints not fully attributable to brain injury, disease, or other neuropathological or psychiatric conditions. FCD…
View details →Bokern M, Tazare J, Rentsch CT et al. · 2025 · Pharmacoepidemiology and drug safety
Background In pharmacoepidemiologic studies of COVID-19, there were concerns about bias from residual confounding. We investigated the effects of inhaled corticosteroids (ICS) on COVID-19 outcomes, applying high-dimensional propensity…
View details →Férat V, Deiber MP, Hasler R et al. · 2025 · Brain topography
Neurofeedback (NFB) therapy based on spectral neuromarkers of Attention-Deficit/Hyperactivity Disorder (ADHD) has faced challenges regarding its efficacy and replicability. In this study, we investigate whether a microstate-based EEG…
View details →Wang Z, Wang B, Wang L · 2026 · PeerJ
Introduction While acute ischemic stroke (AIS) and rhabdomyolysis (RML) have been reported to co-occur, their clinical relationship and associated outcomes remain poorly understood. This study aimed to investigate the clinical…
View details →Pedale T, Karampela O, Eriksson J · 2025 · eNeuro
A key process for successful working memory is to prioritize task-relevant information over distraction, i.e., to control attentional deployment. Here we investigate to what extent attentional control during a delayed match-to-sample task…
View details →Lorente-Piera J, Blanco M, Manrique-Huarte R et al. · 2025 · Audiology research
Background/Objectives : Skull vibration-induced nystagmus (SVIN) is a rapid bedside test that reveals vestibular asymmetry. Its clinical utility in Ménière's disease (MD) remains controversial, particularly regarding its association with…
View details →Gómez-Restrepo C, Roldan MC, Ariza-Salazar K et al. · 2024 · BMC research notes
Objective Adolescents frequently experience mental distress. However, there is little research on community activities that help adolescents recover from depression and anxiety. This study investigated the outcomes and experiences of music…
View details →Wang A, Bao X, Wang C et al. · 2025 · Frontiers in neuroscience
Objective To investigate the changes in the global attributes of structural connectivity (SC) and functional connectivity (FC) graph theory, as well as the coupling topological structure of the whole brain SC-FC in patients with…
View details →Soh CH, Nerlekar N, Whitmore K et al. · 2026 · American journal of preventive cardiology
Background Multiple cardiovascular (CV) risk assessment scores can predict CV events. The current trend towards assessing atheroma has led to these scores being used to identify patients who might benefit from coronary plaque imaging.…
View details →Zeng YF, Wei XY, Wang QG et al. · 2025 · BMJ open
Objective The causal relationship between sleep characteristics and aortic aneurysm and dissection (AAD) is little known. Methods In this two-sample Mendelian randomisation (MR) study, we selected seven sleep-related traits (sleep…
View details →Nguyen HM, Le DHH, Ho TTH et al. · 2026 · The application of clinical genetics
Background Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The TNF-α rs1800629 (-308G/A) polymorphism is an influential factor in disease pathogenesis. However, its association is inconsistent…
View details →Hrnčíř V, Sheehan O, Claessens S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Humans have been using psychoactive substances for millennia, despite their potential negative health and social consequences. According to some scholars, our craving for mind-altering drugs is an evolutionary mistake-a hijacking of our…
View details →Ling W, Li H, Liu L et al. · 2025 · Open heart
Objective To evaluate the association between β-blocker use and all-cause mortality in a real-world cohort of patients with myocardial infarction (MI). Methods This study included 2308 patients with MI from the National Health and…
View details →Yoshikawa N, Masaki H · 2021 · Frontiers in psychology
Previous studies have shown that viewing cute pictures leads to performance improvement in a subsequent fine motor task. We examined the beneficial effects of viewing cute pictures in a more complex sporting skill (i.e., basketball free…
View details →Orr SL, Hershey AD, Kurowski BG et al. · 2026 · Neurology. Genetics
Background and objectives To examine the association between genetic risk of migraine and post-traumatic headache (PTH) in children. Methods This is a secondary analysis of a cohort study that recruited children aged 8-17 years within 48…
View details →Cheng T, Zhang HY, Wang TR et al. · 2025 · Scientific reports
This study uses Mendelian randomization (MR) to investigate the potential causal relationships between viral infections, including Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), SARS-CoV-2, cytomegalovirus (CMV), human…
View details →Diarra NH, Dicko Y, Roschnik N et al. · 2025 · Maternal & child nutrition
A cluster-randomised controlled trial was conducted in 60 communities in southern Mali to evaluate the impact of micronutrient powders (MNP) combined with seasonal malaria chemoprevention (SMC) on anaemia (primary endpoint), Plasmodium…
View details →Mitchell AP, Dusetzina SB, Mishra Meza A et al. · 2025 · BMJ (Clinical research ed.)
Objective To estimate the association between the billing (profit) margin and clinical benefit of cancer treatments and use by oncologists. Design Retrospective population based cohort study SETTING: Population based sample using…
View details →Bierut L, Biroli P, Galama TJ et al. · 2023 · Journal Of Economic Psychology
Smoking is one of the leading causes of preventable disease and death in the U.S., and it is strongly influenced both by genetic predisposition and childhood adversity. Using polygenic indices (PGIs) of predisposition to smoking, we…
View details →Sumner P, Powell G, Price A et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Many people experience aversive hypersensitivity (discomfort/visual stress) to stimuli such as bright lights, striped patterns, strobing, motion, or complex visual scenes such as supermarkets. Such sensory hypersensitivity is often…
View details →Stevens VL, Priest J, Wilkerson J et al. · 2026 · American journal of epidemiology
Weight cycling, when weight is repeatedly lost intentionally and then regained, may perturb biological processes that could influence cancer development. However, results from epidemiologic studies of weight cycling are mixed and provide…
View details →Gershengorn HB, Anesi GL, Liu VX et al. · 2025 · Annals of the American Thoracic Society
Rationale: The association of interprofessional team member workload with intensive care unit (ICU) outcomes is understudied. Objectives: To evaluate the association of patient-to-intensivist ratio (PIR), patient-to-respiratory therapist…
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