Negative / Null Result ReportMedicine
Bürker BS, Brautaset Englund KV, Myrdal Østby C et al. · 2025 · Clinical transplantation
Background Cognitive dysfunction after successful heart transplantation (HTx) is not uncommon. Lower hemoglobin levels have previously been associated with cognitive dysfunction in heart transplant recipients (HTx recipients). In a…
View details →Negative / Null Result ReportMedicine
Eloot S, Erlenkötter A, Zawada AM et al. · 2026 · Artificial organs
To date, it remains unclear to what extent dialyzer performance is affected by clotting, and which hemocompatibility parameters can reliably predict this phenomenon. This study investigated the relationship between dialyzer clotting,…
View details →Negative / Null Result ReportMedicine
Wang Z, Mach J, Chen X et al. · 2025 · Current biology : CB
Honeybee foragers explore the environment before they start foraging, following dances, or performing dances. Foragers are therefore familiar with the landscape surrounding the hive during their foraging career. Here, we ask whether…
View details →Negative / Null Result ReportMedicine
Ardiyanti R, Azrague K, Østerhus SW et al. · 2025 · Chemosphere
The growing demand for phosphorus recovery from wastewater has increased interest in Enhanced Biological Phosphorus Removal (EBPR) processes. However, the fate of per- and polyfluoroalkyl substances (PFAS) in EBPR-derived biosolids remains…
View details →Negative / Null Result ReportMedicine
Wang Z, Xiao F, Chen M et al. · 2025 · Ecological Indicators
In the past few decades, freshwater lakes in the middle and lower reaches of the Yangtze River have experienced significant ecological degradation, with many lakes transitioning from oligotrophic to eutrophic states. In response to this…
View details →Negative / Null Result ReportMedicine
Pohl V, Haas R, Rosen R et al. · 2025 · Clinical implant dentistry and related research
Objective This randomized controlled trial aimed to evaluate the impact of early versus delayed change of abutment on bone levels, soft tissue, and patient satisfaction with single-tooth immediate implants. Material and methods In 26…
View details →Negative / Null Result ReportMedicine
Cuttance E, Nortje R, Laven R et al. · 2025 · The Journal of dairy research
This study compared a culture-based protocol in which only cows identified as having intramammary infections due to major pathogens (major IMI) were treated with dry cow antibiotics (DCAT) compared with the current New Zealand somatic cell…
View details →Negative / Null Result ReportMedicine
Gómez DP, Nicolás VR, Marrero GC et al. · 2026 · American journal of physiology. Gastrointestinal and liver physiology
Hepatocyte nuclear factor 4 A (HNF4A) is a transcription factor that regulates a diverse range of intestinal epithelial genes involved in tissue renewal, differentiation, and metabolism, among other functions. The HNF4A locus is associated…
View details →Negative / Null Result ReportOpen accessMedicine
Martin E, Aigrot MS, Frère N et al. · 2025 · Multiple sclerosis journal - experimental, translational and clinical
Background To recover normal functions, remyelination in multiple sclerosis is crucial. Although endogenous remyelination occurs, it is often insufficient, and finding molecules promoting repair of demyelinated lesions is needed.…
View details →Negative / Null Result ReportMedicine
Swami U, Jo Y, Narang A et al. · 2025 · European urology oncology
Although obesity has been associated with better overall survival (OS) among patients with metastatic castration-resistant prostate cancer, its association with OS has not been extensively explored in metastatic hormone-sensitive prostate…
View details →Negative / Null Result ReportOpen accessMedicine
D'Haens G, Danese S, Panaccione R et al. · 2025 · Journal of Crohn's & colitis
Background and aims Tyrosine kinase 2 is a downstream intracellular mediator of interleukin-23 signaling, which has a key role in the pathogenesis of inflammatory bowel disease. Deucravacitinib is a novel, oral, selective, allosteric…
View details →Negative / Null Result ReportMedicine
Clayton AH, Lasser R, Nandy I et al. · 2023 · The Journal of clinical psychiatry
Objective: To evaluate the efficacy and safety of zuranolone, an investigational neuroactive steroid and GABA A receptor positive allosteric modulator, in major depressive disorder (MDD). Methods: The phase 3, double-blind, randomized,…
View details →Negative / Null Result ReportOpen accessMedicine
Fiorentù G, Bernardinello N, Giulianelli G et al. · 2025 · Advances in therapy
Pulmonary hypertension (PH) is a progressive syndrome characterized by increased pulmonary artery pressure. PH often complicates chronic lung diseases, thus contributing to a substantial disease burden and poor prognosis. The WHO Group 3…
View details →Negative / Null Result ReportMedicine
Bodensohn R, Kaempfel AL, Boulesteix AL et al. · 2023 · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Background and purpose There is no randomized evidence comparing whole-brain radiotherapy (WBRT) and stereotactic radiosurgery (SRS) in the treatment of multiple brain metastases. This prospective nonrandomized controlled single arm trial…
View details →Negative / Null Result ReportOpen accessMedicine
Perez PN, Smesseim I, Sterman DH · 2026 · Immunotherapy
Lung cancer is the leading cause of cancer deaths, and despite therapeutic advances, recurrence and resistance persist. Local tumor ablation can function as an in situ vaccine, but thermal techniques may disrupt antigen and extracellular…
View details →Negative / Null Result ReportMedicine
Gondi V, Pugh SL, Mehta MP et al. · 2025 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Purpose Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial…
View details →Negative / Null Result ReportMedicine
Versteegen E, Wang A, Wang X et al. · 2025 · Aquatic toxicology (Amsterdam, Netherlands)
Pharmaceutical contamination in aquatic environments, particularly from neuroactive drugs like antidepressants, potentially affects the behaviour of non-target organisms due to their effects on conserved neuroendocrine systems. Behavioural…
View details →Negative / Null Result ReportMedicine
Navarrete Sánchez RA, Tognetti PM, Maddonni GA · 2025 · European Journal of Agronomy.
Maize crops are exposed to heat stress, water restrictions, or combined stress during vegetative stages, which can immediately limit crop growth and extend into the flowering period, affecting grain yield. This study evaluated the effects…
View details →Negative / Null Result ReportOpen accessMedicine
Firlana CR, Emril DR, Syahrizal D et al. · 2026 · Narra J
Sciatic nerve injury results in motor dysfunction and muscle atrophy, with limited effective therapies. Umbilical cord-derived mesenchymal stem cells (UC-MSCs) may promote neuromuscular recovery, but their effects on functional and muscle…
View details →Negative / Null Result ReportMedicine
Lee NH, Kim B, Yoo KH · 2025 · Cancer research and treatment
Purpose Mesenchymal stromal cells (MSCs), while regarded as promising immunomodulatory tools, have raised concerns in recent studies for their potential to promote tumor growth or facilitate immune evasion. These risks are particularly…
View details →Negative / Null Result ReportMedicine
Telfar-Barnard L, Beautrais A, Anglemyer A · 2025 · Annals of internal medicine
Background There have been multiple changes to the Arms Act 1983 in Aotearoa New Zealand (NZ) which have subsequently been associated with reductions in firearm-related suicide. In response to the worst mass shooting in NZ's history,…
View details →Negative / Null Result ReportMedicine
Kougkas N, Skouvaklidou E, Tsafis K et al. · 2026 · Clinical and experimental rheumatology
Objectives Janus kinase inhibitors (JAKi) are increasingly used to treat autoimmune rheumatic diseases (ARDs), despite concerns regarding their potential cardiovascular risks. Cardiac strain, a sensitive marker for subclinical myocardial…
View details →Negative / Null Result ReportOpen accessMedicine
Büyükpolat M, Aydın N, Eryılmaz B et al. · 2025 · BMC oral health
OBJECTIVE: The use of polishing pastes in the final surface preparation of resin composite restorations has become increasingly common. This study aimed to evaluate the effects of polishing pastes containing abrasives of different particle…
View details →Negative / Null Result ReportOpen accessMedicine
Rasmussen MIS, Hansen ML, Pellicer A et al. · 2026 · JAMA pediatrics
Importance Cerebral oximetry monitoring in the first 72 hours after birth has not been shown to reduce death or severe brain injury at 36 weeks' postmenstrual age in extremely preterm infants. The long-term effects remain uncertain.…
View details →Negative / Null Result ReportMedicine
Rossi HS, Mykkänen AK, Teppo AM et al. · 2025 · Journal of equine veterinary science
Pneumonia is a common condition in young, hospitalized foals, causing accumulation of inflammatory secretions to the airways. In humans, respiratory physiotherapy is commonly used as a supplementary treatment for pneumonia with varying…
View details →Negative / Null Result ReportOpen accessMedicine
Suvorov VV, Sayitkuliev DB · 2026 · Diseases (Basel, Switzerland)
The development of sternal infection in neonates after cardiac defect correction using median sternotomy is a serious complication, increasing the length of hospital stay, mortality, and treatment costs. One effective method for preventing…
View details →Negative / Null Result ReportMedicine
de Lima Cruz GF, Pereira OG, Alves WS et al. · 2025 · Tropical animal health and production
Tropical grasses are widely used for silage, but their high fiber content and variable quality often limit ruminal degradation and animal performance. Strategies such as optimizing regrowth age (RA) and applying fibrolytic enzymes may help…
View details →Negative / Null Result ReportOpen accessMedicine
Sadeghi M, Shahrooz S, Aghamohammadi M et al. · 2025 · BMC research notes
Objective Asthma is a common multifactorial inflammatory disease affecting both children and adults. Various cells and cytokines contribute to this inflammatory process. Smooth muscle contraction, vascular congestion, and airway edema lead…
View details →Negative / Null Result ReportOpen accessMedicine
Pan X, Sarker S, Yu JJ et al. · 2026 · Insects
High rates of pest infestations are frequently reported in low-income homes in the U.S. However, even with access to effective insecticides, most residents are unaware of how to properly control indoor pests. We designed and evaluated the…
View details →Negative / Null Result ReportMedicine
Kass C, Katz-Greenberg G, Bodner J et al. · 2025 · Transplant immunology
Purpose Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The…
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