Negative / Null Result ReportMedicine
Kuznetsova DA, Kuznetsov DM, Lyubina AP et al. · 2026 · Biochimica et biophysica acta. Biomembranes
The design of effective non-viral nucleic acid delivery systems based on cationic amphiphilic compounds remains a major challenge in biomedical research. In this study, cationic benzimidazolium surfactants (BI-n) and cationic liposomes…
View details →Negative / Null Result ReportMedicine
Nakagawa A, Matsuoka Y, Seo M et al. · 2026 · Circulation journal : official journal of the Japanese Circulation Society
Background Patients with heart failure with preserved ejection fraction (HFpEF) and right ventricular (RV)-pulmonary arterial (PA) uncoupling, as assessed by a decrease ratio of tricuspid annular plane systolic excursion (TAPSE) to PA…
View details →Negative / Null Result ReportMedicine
Hussain SK, Ayoub WS, Cruz-Correa M et al. · 2026 · Cancer prevention research (Philadelphia, Pa.)
Hepatocellular carcinoma (HCC) is a lethal cancer with rising burden. Few clinical trials have evaluated preventive strategies for HCC in high-risk patients with liver cirrhosis. Observational studies show statins are associated with…
View details →Negative / Null Result ReportMedicine
Kumar N, Prasad S, Srivastava MVP et al. · 2026 · The Journal of clinical psychiatry
Background: Negative symptoms remain among the most debilitating and treatment-resistant features of schizophrenia. Repetitive transcranial magnetic stimulation, particularly intermittent theta burst stimulation (iTBS), is emerging as a…
View details →Negative / Null Result ReportMedicine
Cowan C, Harmon EY, Melewski M et al. · 2026 · The American journal of occupational therapy : official publication of the American Occupational Therapy Association
Importance Understanding how upper extremity (UE) robotic therapy (RT) affects efficiency and effectiveness of inpatient rehabilitation is important to advancing poststroke treatment and recovery. Objective To determine whether UE RT…
View details →Negative / Null Result ReportMedicine
Abdelgaied MY, Abdelgawad O, Rashad MH et al. · 2026 · Journal of neuroimmunology
Background Neurodegeneration and inflammation can accelerate the demyelination process in multiple sclerosis (MS). We aimed to investigate the efficacy and tolerability of metformin as an add-on treatment to interferon Beta 1a (IFNβ-1a) in…
View details →Negative / Null Result ReportOpen accessMedicine
Aust H, Kranke P, Torossian A et al. · 2026 · Cancers
Background Isolated Perfusion Chemotherapy (IPC) with balloon occlusion creates transient ischemic tissue compartments while patients remain exposed to significant perioperative heat loss. Active warming during these phases is commonly…
View details →Negative / Null Result ReportMedicine
Mohar S, Crawford AM, Vásquez US et al. · 2026 · BMC medical education
Background Effective airway management is essential for patient safety across prehospital, perioperative, and critical care settings. Traditional training, largely based on lectures and brief skills stations, may be insufficient to develop…
View details →Negative / Null Result ReportMedicine
Jeppesen TD, Jedrzejczyk JH, Vingborg AL et al. · 2026 · Cardiovascular engineering and technology
Purpose Freeze-preservation of porcine aortic tissue is often necessary for experimental planning and standardization, but the impact of freezing on aortic root properties has not been systematically investigated. This study evaluated the…
View details →Negative / Null Result ReportMedicine
Kretzschmar HA, Abouabdillah A, Bouabid R et al. · 2026 · Potato Res..
The Fès-Meknès region in Morocco is characterized by a typical Mediterranean climate and the cultivation of water-demanding, locally well-established cash crops, such as potato (Solanum tuberosum L.). Therefore, this region is likely to…
View details →Negative / Null Result ReportMedicine
Takahashi K, Kawagoe J, Takehara I et al. · 2026 · Reproductive sciences (Thousand Oaks, Calif.)
This study examined whether oral administration of individual short-chain fatty acids (SCFAs) alters Treg- and Th17-related immune parameters during the peri-implantation period in pregnant mice. Using a mouse model, the effects of SCFAs…
View details →Negative / Null Result ReportMedicine
Choi JY, Yu OJ, Yun JY et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Purpose The role of deltoid ligament (DL) repair in supination-external rotation (SER)-type trimalleolar equivalent ankle fractures (TEAFs) remains controversial. Additionally, it remains unclear whether posterior malleolar fixation alone…
View details →Negative / Null Result ReportMedicine
Mathai SK, Callahan SJ, Chang H et al. · 2026 · Annals of the American Thoracic Society
Rationale The optimal treatment of interstitial lung disease resulting from COVID-19 is unknown. Objectives We sought to investigate the effect of nintedanib, an antifibrotic medication, on interstitial lung disease in participants who…
View details →Negative / Null Result ReportMedicine
Peanchitlertkajorn S, Makkasaman K, Neoh SP et al. · 2026 · Journal of the World federation of orthodontists
Background To evaluate the cytotoxicity of direct 3D-printed aligners fabricated from Tera Harz TC-85DAC resin (TC) compared with conventional thermoformed aligners, and to investigate the effect of different post curing durations on TC…
View details →Negative / Null Result ReportMedicine
Liu J, Nassrallah W, Quan-Nguyen C et al. · 2026 · Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Objective The progression of glaucoma despite adequate intraocular pressure (IOP) control highlights the need for neuroprotective and neuroregenerative therapies. Preclinical studies suggest insulin promotes retinal ganglion cell survival…
View details →Negative / Null Result ReportMedicine
Brown JAR, Brewis HT, Kobor MS · 2026 · DNA repair
A range of genome maintenance factors respond to endogenous and exogenous DNA damage to prevent mutations and cell death. The scaffold protein, Rtt107, is important for the growth of cells exposed to DNA-damaging agents in the budding…
View details →Negative / Null Result ReportMedicine
van der Meulen LWJ, Bergmans ME, Assil S et al. · 2026 · British journal of clinical pharmacology
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this…
View details →Negative / Null Result ReportMedicine
Chakraborty S, Chatterjee S, S P et al. · 2026 · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Introduction The HYPORT Adjuvant trial is comparing a one-week (26 Gy) course of adjuvant breast radiotherapy (RT) to a three-week (40 Gy) course. We report the interaction of regional nodal irradiation (RNI) and the dose fractionation…
View details →Negative / Null Result ReportMedicine
Sumner C, Patel P, Spencer A et al. · 2026 · Journal of pediatric urology
Introduction Circumcision is a common surgical intervention, and pain is the most common complaint. Poorly managed pain can increase morbidity and reduce patient and parent satisfaction. Ketorolac, a non-steroidal anti-inflammatory drug…
View details →Negative / Null Result ReportMedicine
Lim W · 2026 · Physiotherapy research international : the journal for researchers and clinicians in physical therapy
Background and purpose Joint position sense (JPS) is frequently assessed using joint position reproduction (JPR); however, JPR has limitations, where reference angles are typically unavailable. This study aimed to examine the accuracy of…
View details →Negative / Null Result ReportMedicine
Lachowski K, Naja KM, Prill R et al. · 2026 · Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Purpose Robotic-assisted (RA) surgery allows for higher accuracy in total knee arthroplasty (TKA) and for better standardization of alignment concepts. It was hypothesized that the more personalized component placement in functional…
View details →Negative / Null Result ReportMedicine
Murray AL, Dryburgh K, Sonuga-Barke EJS · 2026 · Journal of attention disorders
Objective ADHD and internalising symptoms such as anxiety and depression are known to be associated in adolescence and understanding the mechanisms linking them is important for improving mental health outcomes for adolescents with ADHD…
View details →Negative / Null Result ReportMedicine
Yoo S, von Keyserlingk MAG, Weary DM · 2026 · Journal of dairy science
Hot-iron disbudding is the most commonly used method for horn bud removal in dairy calves. Although factors such as post-treatment care, calf age, and the type of hot iron used have been studied in relation to wound healing, procedural…
View details →Negative / Null Result ReportMedicine
Liang R, Mei L, Ding J et al. · 2026 · Journal of hazardous materials
Biodegradable plastic mulches (BDMs) are increasingly promoted as environmentally friendly alternatives to conventional mulches. However, the ecological impacts of different BDMs on soil remains incompletely understood. A field experiment…
View details →Negative / Null Result ReportMedicine
Kumagai K, Hasegawa T, Kutsuzawa D et al. · 2026 · Journal of cardiovascular electrophysiology
Background The role of dominant frequency (DF)-guided ablation after pulmonary vein isolation (PVI) in persistent atrial fibrillation (AF) remains uncertain. We evaluated the clinical and mechanistic impact of DF mapping in a multicenter…
View details →Negative / Null Result ReportMedicine
Kirkham MS, Carlson HB, Merrill E et al. · 2026 · Journal of shoulder and elbow surgery
Hypothesis Cutibacterium acnes is the most frequent cause of shoulder prosthetic joint infection with skin edges as a source of wound contamination. The primary purpose of this study was to determine if the use of a wound protector device…
View details →Negative / Null Result ReportMedicine
Mkrtchjan A, Ntantou E, Siskos AA et al. · 2026 · The Journal of invasive cardiology
Objectives The authors aimed to investigate the impact of clinical presentation on 1-year major adverse cardiac events (MACE) in patients with angiographically defined moderate or severe calcified coronary artery disease. Methods The…
View details →Negative / Null Result ReportMedicine
Reddy SC, Tran K, Li X et al. · 2026 · Foot & ankle specialist
BackgroundThree-Dimensional Distance and Coverage Mapping (DM and CM) generated through weightbearing CT (WBCT) can aid in understanding the complex articular relationship in hallux valgus (HV). Prior studies have demonstrated that…
View details →Negative / Null Result ReportMedicine
Frémont L, Casagranda L, Sudour-Bonnange H et al. · 2026 · Journal of adolescent and young adult oncology
Purpose This study aimed to evaluate the cardiovascular medical management of young adults who had viewed the massive open online course (MOOC) "Childhood Cancer, Living Well, After" four years earlier during the feasibility study…
View details →Negative / Null Result ReportMedicine
Hough J, Gouveia M, Steele M et al. · 2026 · Physiotherapy
Objective Evaluate the impact of lung ultrasound (LUS) compared to current chest physiotherapy (CPT) outcome measures on clinical decision-making in the Neonatal Intensive Care Unit (NICU). Design and setting Single-centre prospective…
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