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Browse the failure-mode index

11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Temperature at admission and mortality in older adults with infection: Limited prognostic value in non-sepsis cases.

Nielsen FE, Abdullah OB, Chafranska L et al. · 2026 · The American journal of emergency medicine

Background Temperature abnormalities are established prognostic markers in sepsis, but their predictive value in older adults with infection without sepsis remains unclear. Objective To examine the association between arrival temperature…

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Negative / Null Result ReportMedicine

The impact of exposure to additional languages and cognitive factors on narrative macrostructure in autistic and neurotypical children.

Wolfer P, Tselekidou F, Baumeister F et al. · 2026 · Journal of communication disorders

This study adopts a twofold approach to examine how bilingual exposure and (socio-)cognitive factors influence narrative macrostructure in children. First, it investigated the impact of Exposure to Additional Languages (EtAL) on the…

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Negative / Null Result ReportMedicine

Forecasting Local Surges in COVID-19 Hospitalizations through Adaptive Decision Tree Classifiers.

Murray-Watson RE, Guaracha X, Bilinski A et al. · 2026 · Medical decision making : an international journal of the Society for Medical Decision Making

IntroductionDuring the COVID-19 pandemic, many communities across the United States experienced surges in hospitalizations, which strained the local hospital capacity. Some risk metrics, such as the Center for Disease Control and…

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Negative / Null Result ReportMedicine

Usefulness of uric acid-to-high-density lipoprotein cholesterol ratio for the evaluation of insulin resistance in healthy normoglycaemic and normoinsulinaemic men.

Kaneva AM, Bojko ER · 2026 · Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association

Uric acid-to-high-density lipoprotein cholesterol ratio (UHR) is a novel and promising marker for metabolic abnormalities. Recent studies have demonstrated that UHR is related to a number of diseases that are caused by insulin resistance.…

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Negative / Null Result ReportMedicine

What works for whom in outpatient cognitive-behavioral therapy? Integration of techniques from different therapeutic orientations and their interactions as predictors of treatment outcome in different diagnostic groups.

van Alebeek H, D'Errico L, Delgadillo J et al. · 2026 · Journal of consulting and clinical psychology

Objective The mechanisms underlying psychotherapy's effects remain debated, with some emphasizing theory-specific therapeutic techniques and others highlighting common factors like therapeutic alliance. Evidence is inconclusive partially…

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Negative / Null Result ReportMedicine

Container Mosquito Abundance in Brooklyn Community Gardens.

Kelley AT, Boger R · 2025 · EcoHealth

Community gardens in urban Brooklyn, New York are social spaces that provide food sovereignty to many New Yorkers, but the arrival of the mosquito Aedes albopictus and longtime presence of Culex pipiens makes socializing in these spaces…

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Negative / Null Result ReportMedicine

Views of aging and symptoms of posttraumatic stress disorder among older adult war veterans in the context of renewed war.

Avidor S, Shenkman G, Shrira A et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives For aging combat veterans, experiencing renewed war in old age can exacerbate coping with age-related challenges. The present study sought to examine how past and current war-related stressors affect long-term trajectories of…

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Negative / Null Result ReportMedicine

Does earlier mobilization reduce venous thromboembolism after spine surgery?

Ng MK, Mathew J, Dalton J et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

PURPOSE: Venous thromboembolism (VTE) is an uncommon but potentially devastating complication following spine surgery. Although early mobilization is encouraged as a preventive measure, the influence of inpatient physical therapy on VTE…

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Negative / Null Result ReportOpen accessMedicine

Childhood Linear Growth and Early Morbidity as Predictors of Adolescent Cognitive Ability in Malawi: A Prospective Observational Study.

Videman K, Leppänen JM, Hallamaa L et al. · 2026 · Acta paediatrica (Oslo, Norway : 1992)

Aim Growth faltering and loss of development potential are common in low- and middle-income countries. We aimed to study whether linear growth before and after 2 years, height-for-age Z-score (HAZ) from 1 month until 13 years and morbidity…

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Negative / Null Result ReportMedicine

Association of QTc Dispersion with Mortality, Intensive Care Unit Admission, Intubation, and Hospital Stay Duration in Acute Methadone Poisoning.

Taherkhani A, Yeganegi H, Tavasol A et al. · 2026 · Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir

Objective The objective of this study is to investigate the prognostic significance of QTc dispersion (QTcd) in patients with acute methadone poisoning and its association with critical clinical outcomes, including mortality, Intensive…

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Negative / Null Result ReportMedicine

Systematic reexamination of early verb dominance: Verbal and nonverbal characteristics of caregiver input and their contribution to long-term language outcomes.

Kim M, Mun J, Kim G et al. · 2026 · Developmental psychology

Early language input to infants varies in lexical composition across languages and contexts. For instance, American-English input emphasizes nouns more than verbs, while Mandarin Chinese and Korean inputs provide more verbs than nouns, the…

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Negative / Null Result ReportMedicine

Social attunement and alcohol use: The role of age and gender.

Romein C, Colyer-Patel K, Kroon E et al. · 2026 · Addictive behaviors

Background Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…

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Negative / Null Result ReportMedicine

Personality profiles and trauma history in ketamine therapy for mood and anxiety disorders: A latent profile analysis of short-term outcomes.

Gregoire N, Klukas E, Kaseweter K et al. · 2025 · Psychopharmacology

Rationale Ketamine-assisted therapy is emerging as a fast-acting intervention for treatment-resistant depression and anxiety. However, individual response to treatment varies, and little is known about how personality traits and trauma…

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Negative / Null Result ReportMedicine

Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs.

Jones N, Humm K, Tinson EW · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial…

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