11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Vanhanen EJ, Lehtimäki TE, Kolho KL et al. · 2026 · Therapeutic advances in gastroenterology
Background The prognostic value of magnetic resonance imaging (MRI) in pediatric-onset primary sclerosing cholangitis (PSC) remains poorly studied. The MRI-based ANALI scores with and without gadolinium (ANALI Gd and ANALI NoGd ) have…
View details →Habaguchi A, Katano S, Yano T et al. · 2026 · Circulation journal : official journal of the Japanese Circulation Society
Background Whether the components of sarcopenia provide sex-specific prognostic information in heart failure (HF) remains uncertain. Methods and results We enrolled 604 patients with HF (259 women; median age, 73 years) undergoing…
View details →Kirkham R, Aidman E, Yücel M et al. · 2026 · Journal of affective disorders
Burnout is a prevalent and costly work-related condition characterized by four symptom dimensions: cognitive impairment, emotional impairment, mental distance and exhaustion. Although coping, coping flexibility, and cognitive flexibility…
View details →Hewitt KM, Bayliss DM, McLean BA et al. · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence
Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While…
View details →Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal
Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…
View details →Au-Yeung C, Christophe NK, Lavigne KM et al. · 2026 · Schizophrenia research
Background Cognitive impairments and negative symptoms (NS) represent an unmet therapeutic need in psychotic disorders. Both NS and cognitive impairments, are key predictors of functioning. Both also appear during the illness prodrome,…
View details →Bertamini M, Lucia M, Diaz S et al. · 2025 · British journal of psychology (London, England : 1953)
Since antiquity humans have been fascinated by mirrors; yet, when asked to predict what is made visible in the reflection, or to interpret a scene with a mirror, observers make systematic errors. Many observers claim that a character in a…
View details →Bektas D, Lanzino G, Flemming KD · 2026 · Journal of neurosurgery
Objective This study evaluated the utility of routine versus symptom-driven MRI to detect hemorrhage in patients with sporadic cerebral cavernous malformations (CCMs) and assessed associated radiographic changes at the first clinical…
View details →Carreras JP, Carney BC, Lee D et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association
Skin fibrosis, especially hypertrophic scars (HTS), remains understudied with few effective treatments. Studying HTS is challenging due to its natural tendency to improve over time, making it hard to separate intervention effects. This…
View details →Rabinowitz JA, Masyn K, Thomas N et al. · 2026 · Drug and alcohol dependence
Objective Using a latent change score modeling approach, we tested the bidirectional relationships between spirituality and craving during the first month of substance use disorder (SUD) treatment. Specifically, we examined whether higher…
View details →Jubas S, Collins K, Obara K et al. · 2026 · Transplantation and cellular therapy
Background Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for hematologic malignancies. However, relationships between donor chimerism and clinical outcomes remain poorly characterized. Objective The…
View details →Abaei E, Martin P · 2026 · Aging & mental health
Objectives Using data from the Health and Retirement Study (1992-2020), this study investigates how cognitive function and its longitudinal changes influence trajectories of depressive symptoms among oldest-old adults. Method Latent growth…
View details →Koivu N, Lankinen M, Schwab U · 2026 · Health education & behavior : the official publication of the Society for Public Health Education
Sustained dietary change is essential for type 2 diabetes prevention, yet most Finnish men do not follow dietary recommendations. Eating behavior traits such as cognitive restraint, uncontrolled eating, and emotional eating may influence…
View details →Aygun TM, Ozkara G, Balin Duzguner IN et al. · 2026 · Zygote (Cambridge, England)
Recurrent pregnancy loss (RPL) is a clinically important condition in women undergoing assisted reproductive technologies (ART). This study evaluated embryo morphology and morphokinetic parameters using time-lapse monitoring (TLM) and…
View details →McNeil J, Logel C, Rehman US · 2026 · Journal of sex research
Sexual problems in relationships are negatively correlated with sexual satisfaction, but the direction of this relationship remains unclear. Although most theorizing posits that changes in sexual problems precede changes in sexual…
View details →Laas MM, Wright M, Enright K et al. · 2026 · Research quarterly for exercise and sport
This study analyzed the longitudinal relationship between short sprints and counter movement jump (CMJ) in youth male soccer players. Players ( n = 304, age 13.0 ± 1.9 years) from a Scottish soccer academy completed sprints (10 m, 20 m…
View details →Barton JM, Eagleton SG, Reyes LI et al. · 2026 · Appetite
Parental feeding practices (hereafter referred to as feeding practices) influence child weight outcomes, but few studies have identified which obesogenic risk factors shape their feeding practices using an ecological approach, especially…
View details →Ferensztajn-Rochowiak E, Rybakowski F, Michalak M et al. · 2026 · Journal of affective disorders
Objectives Treatment resistance in major depressive disorder (MDD) affects nearly 30% of patients, and early childhood trauma (CT) may play a significant role in its development. The international PROMPT project investigates the…
View details →Thumsová B, Martínez-Silvestre A, Pérez-Vallejo M et al. · 2025 · Current biology : CB
The thermal mismatch hypothesis (TMH), the notion that cool- and warm-adapted hosts have higher infection risk during unusually warm and cool spells, respectively, was recently proposed to explain how temperature shifts driven by climate…
View details →Fridberg G, Amit O, Sherf Y et al. · 2026 · Haematologica
CAR-T has transformed relapsed/refractory LBCL treatment, with CD28-based products yielding rapid responses but higher ICANS rates. With Axicabtagene-ciloleucel and Brexucabtagene-autoleucel, overall and severe ICANS reach 78% and 35%,…
View details →Pedraza A, Castaño S, Pereira A et al. · 2026 · British journal of haematology
Despite red blood cell (RBC) immunization being a frequent complication of chronic transfusion in myelodysplastic syndromes (MDS), its prognostic significance remains unclear. We analysed 486 transfused patients diagnosed with MDS.…
View details →Sevik HO, Aytepe O, Kilic MK et al. · 2026 · Journal of laparoendoscopic & advanced surgical techniques. Part A
Introduction Red cell distribution width (RDW) has recently emerged as a potential biomarker reflecting nutritional and inflammatory status in surgical oncology. While anastomotic leakage (AL) remains a devastating complication after right…
View details →Reyna NC, Hamilton DA · 2026 · Hippocampus
Alzheimer's disease (AD) is characterized by irreversible neurobiological deterioration and cognitive impairment. AD patients exhibit stress system abnormalities including upregulation of the corticotropin releasing factor type 1 receptor…
View details →Moreira FC, Ribeiro MS, Costa CAS et al. · 2026 · Photochemistry and photobiology
Photobiomodulation (PBM) using red LED light (630 nm) has been investigated for its ability to modulate cellular functions relevant to tissue regeneration. This in vitro study evaluated the effects of PBM on the viability, metabolism, and…
View details →Chen YC, Chang HJ, Chang CW et al. · 2026 · Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
Introduction Delirium is a common and serious complication in critically ill patients, associated with higher mortality, prolonged intensive care unit (ICU) stays, and cognitive impairments. Furthermore, renal dysfunction is a…
View details →Guérémy A, Morel V, Stojkovic T et al. · 2026 · Muscle & nerve
Introduction/aims LGMDR8 is a very rare autosomal recessive limb-girdle muscular dystrophy caused by variants in the TRIM32 gene. To date, 92 cases have been reported, mainly in the Hutterite population with a founder effect. This study…
View details →Ladwig G, Schönhals K, Tanck JA et al. · 2025 · Scientific reports
As exposure to fitspiration images can lead to body dissatisfaction, it is important to understand which factors contribute to this effect. Therefore, this online experiment examined possible predictors of state body dissatisfaction…
View details →Engelmann P, Busmann M, Löwe B et al. · 2026 · Journal of psychosomatic research
Background Biopsychosocial mechanisms are assumed to underlie the chronification of back pain; however, potentially relevant factors have mainly been examined in isolation rather than within comprehensive aetiological models. This study…
View details →Hill AL, Yu L, Miller E et al. · 2026 · Violence and victims
Structural equation modeling (SEM) allows for the examination of complex relationships between violence and associated behaviors. We sought to understand the bidirectional longitudinal associations between sexual violence (SV)…
View details →Eerdekens R, Johnson NP, Adrichem R et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Background Assessing aortic stenosis (AS) haemodynamics under stress may distinguish physiological responses beyond traditional severity metrics. Aims We aimed to evaluate symptomatic patients with moderate AS and preserved left…
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