11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Ku X · 2026 · Addictive behaviors
Emerging evidence suggests a positive link between parental and child problematic smartphone use (PSU), yet the direction and reciprocity of this relationship over time remain unclear. Here, we address this gap by examining six years…
View details →de Angelis M, Siech C, Di Bello F et al. · 2025 · World journal of urology
Introduction Based on prospective trials' result, it is unknown whether race/ethnicity affects the magnitude of cancer-specific survival differences after trimodal therapy (TMT) versus external beam radiation therapy alone (EBRT) for…
View details →Cho E, Chorpita BF, Reeder K et al. · 2025 · Journal of consulting and clinical psychology
Objective Personalizable modular treatments may be helpful in addressing the mental health needs of minoritized youths. We used data from five randomized effectiveness trials of the Modular Approach to Therapy for Children, a…
View details →Ying Y, Meng R, Xu J et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives The associations between insomnia symptoms and internalizing symptoms are well-established, particularly in older adults; however, the mediating factors remain inconsistent. This study seeks to explore the longitudinal…
View details →Waks JW, Poulin MF, Clarke JD et al. · 2026 · JAMA cardiology
Importance Transcatheter aortic valve replacement (TAVR) to treat aortic stenosis is complicated by heart block requiring permanent pacemaker implantation in at least 10% of cases. Objectives To better understand mechanisms underlying…
View details →Zhou DD, Lord SJ, Lin FP et al. · 2026 · Lung cancer (Amsterdam, Netherlands)
Background In NSCLC, TP53 mutations are heterogeneous with varied effects on protein synthesis, function and clinical outcomes. We hypothesize that a refined classification of TP53 mutations, beyond binary categorization, could improve…
View details →Peckler GL, Adcock SJJ · 2025 · Research in Veterinary Science
Mastitis is a major concern in sheep farming. Detecting subclinical mastitis, which manifests without apparent signs, is particularly challenging. While somatic cell count (SCC) and the California Mastitis Test (CMT) are widely used in…
View details →Coşkun Yaş S, Üçöz Kocaşaban D, Güler S et al. · 2026 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Optic nerve sheath diameter (ONSD) measurement is a non-invasive marker of intracranial pressure. Its role in predicting post-thrombolytic intracranial hemorrhage in acute ischemic stroke patients remains unclear. This study aimed to…
View details →Kim J, Lee YY, Kim TJ et al. · 2026 · International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Objective Sarcopenia is a known adverse prognostic factor in gastrointestinal cancers undergoing bowel resection; however, its prognostic relevance in epithelial ovarian cancer remains unclear. This study aimed to evaluate the prognostic…
View details →Liang J, Pillai T, Chopra S et al. · 2025 · Aesthetic surgery journal
Background Utilization of glucagon-like peptide-1 receptor agonists (GLP-1ras) has increased dramatically in recent years. Although GLP-1ras appear safe to use overall, it remains unclear whether preoperative GLP-1ra use impacts body…
View details →Jourde HR, Ujevco A, Coffey EBJ · 2025 · NeuroImage
Slow oscillations and sleep spindles are neural events that both occur during non-rapid eye movement sleep and are implicated in sleep-dependent memory consolidation. Their temporal co-occurrence, or 'coupling', is thought to support…
View details →Holmgren K, Fletcher-Sandersjöö A, Sæmundsson B et al. · 2026 · Journal of neurosurgery
Objective Postoperative surgical site infections (SSIs) following brain tumor surgery frequently necessitate wound revision and bone flap removal. However, data on subsequent cranial reconstruction in this context remain limited. The aim…
View details →Roach A, Furman S, Hadeed J et al. · 2025 · American journal of primatology
Assessments of nonhuman primate (NHP) affiliation are typically restricted to daytime behavior. There is, however, a growing interest in understanding NHP behavior and welfare over the 24-h period. To assess the sleep quality and sociality…
View details →Ahmed I, Dhaif F, Bowes MA et al. · 2025 · The bone & joint journal
Aims The aim of this study was to describe the baseline characteristics of patients with a meniscal tear and explore associations with 12-month outcomes. Methods This prospective, national multicentre cohort study recruited patients aged…
View details →Holmgren HG, Densley RL, Coyne SM et al. · 2026 · Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43)
Prior research suggests a link between maternal depression and mothers' problematic media use (PMU), defined as compulsive or dysregulated media use that interferes with daily functioning. This study examined whether parenting…
View details →Naylor A, Keegan R, Martin K et al. · 2025 · Journal of sports sciences
Physical literacy has been shown to relate to children's engagement in physical activity. However, it is unclear whether this relationship extends to adults. A two-phase cross-sectional study was conducted to examine whether physical…
View details →Waddell JT, DeFalco A, Emery NE · 2026 · Addictive behaviors
Rationale Impaired control over alcohol use is a core aspect of Alcohol Use Disorder symptomatology. However, research regarding how impaired control manifests at the day-level, and what temporally proceeds it in daily life, remains…
View details →Pratyusha K, Chaitanya P, Vinay C et al. · 2025 · European oral research
Purpose The aim of this study was to evaluate the effect of using an intraoral camera (IOC) as an educational aid for promoting oral health among 7-10-year-old children in India. Materials and methods A randomized trial was conducted…
View details →Vogelsang M, Schäfer A, Ehrenreich A et al. · 2025 · Journal of Experimental Child Psychology
Studies on the development of sharing resources as one aspect of prosocial behavior have revealed that single recipient characteristics affect preschoolers’ sharing decisions. In the current study, we investigated (a) whether preschoolers…
View details →Sookud S, Martin I, Gillan CM et al. · 2026 · Biological psychiatry. Cognitive neuroscience and neuroimaging
Background Diminished use of goal-directed (model-based) decision making is a hallmark of transdiagnostic compulsivity, promoting an overreliance on inflexible and habitual behaviors. However, the origin of this impairment remains unclear.…
View details →Mehari KR, Schuler KR, Haiflich A et al. · 2025 · Violence and victims
This study examined the implementation of a state law in the southern United States that required hospitals to report gunshot wounds (GSWs) to law enforcement by exploring changes in the proportion of reported GSW cases in a level 1 trauma…
View details →Hernández L, Williamson TM, Campbell T et al. · 2025 · The Canadian journal of cardiology
Background Cardiac rehabilitation (CR) participation improves depressive and anxious symptoms post-coronary catheterization, yet it is unclear to what extent improvements are clinically significant. This study characterized the proportion…
View details →Ivanov YV, Kartashov AV, Ivanova AI et al. · 2026 · Functional plant biology : FPB
Global climate change is accompanied by an increase in the frequency and severity of droughts, which negatively impact plant growth. One of the protective mechanisms that allows plants to withstand the negative drought effects is the…
View details →Lanham BS, Morris RL · 2026 · Marine environmental research
The strength of biotic stressors (i.e., predation) can determine the success of shellfish reef restoration projects. In recruitment limited systems where seeding is a common restoration strategy, ensuring the survival of seeded individuals…
View details →Turner KM, Svegborn A, Robbins TW · 2026 · Psychopharmacology
Rationale Recent research on habits and skills has produced a wave of new theories regarding the shift in control from medial to lateral regions of the dorsal striatum, and how these regions are implicated in the selected and executed of…
View details →Aumtong S, Soongsoongnoen P, Wanwinit D · 2026 · Scientific reports
Biochar reshapes soil composition for years, yet most evidence comes from short-term, single-element laboratory incubations, leaving multi-element dynamics in tropical soils poorly resolved. We tracked 11 elements in longan-wood biochar…
View details →Heled E, Himai Y, Papelbaum M et al. · 2026 · Journal of psychiatric research
Impaired cognitive flexibility (CF) and elevated perfectionism are well-documented in anorexia nervosa (AN), yet their contribution to symptom severity remains unclear. The current study aimed to examine whether CF predicts symptom…
View details →Pirbornatan A, Chalmeh A, Pourjafar M et al. · 2026 · Veterinary journal (London, England : 1997)
Periparturient immunometabolic adaptations yield small, node-dependent shifts in endotoxin proxies and insulin-sensitivity indices. Direct-fed microbials (DFM) are mechanistically plausible but often produce modest metabolic readouts. Test…
View details →Hura A, Green T, Kennedy C · 2026 · Archives of environmental contamination and toxicology
With increasing petroleum transport through coastal waters of the northeastern Pacific, understanding the ecological hazards of these mixtures is essential, yet the sublethal impacts on benthic filter feeders remain poorly characterized.…
View details →Jorgensen E, Modahl L, Noll A et al. · 2026 · The Journal of the Acoustical Society of America
This study investigated how hearing loss and hearing aid use affect environmental sound ratings in laboratory and real-world contexts using the soundscape framework. Forty-four participants (17 normal hearing, 14 with unaided hearing loss,…
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