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11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Are dating and sexual Protective Behavioral Strategies (PBS) associated with alcohol-related consequences at all levels of alcohol use?

Peterson R, Paitan SC, Belitsos OA et al. · 2026 · Experimental and clinical psychopharmacology

Alcohol use is common among college students and often linked to negative consequences. Protective behavioral strategies (PBS) can reduce alcohol use and related harms. This study examined whether dating/sexual PBS provide unique…

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Negative / Null Result ReportMedicine

Breaking the PROMISE: poor association between brain volume loss and clinical disability worsening over 2 years of follow-up in primary progressive multiple sclerosis.

Koch M, Mostert J, Strijbis EM et al. · 2026 · Journal of neurology, neurosurgery, and psychiatry

Background Phase 2 clinical trials in primary progressive multiple sclerosis (PPMS) often use MRI brain volume measures as their primary endpoint. Here, we investigate the longitudinal association between change in MRI outcomes and change…

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Negative / Null Result ReportMedicine

High-frequency Ultrasound Evaluation of Midline Crossing-over Vessel: Correlation with Perfusion of Deep Inferior Epigastric Perforator Flap.

Lee SJ, Han HH, Eom JS et al. · 2026 · Plastic and reconstructive surgery

Background The deep inferior epigastric perforator (DIEP) flap is widely used in autologous breast reconstruction, with its success heavily reliant on the vascular anatomy, particularly midline crossing-over vessels that facilitate…

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Negative / Null Result ReportMedicine

Investigating the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) Executive Errors Scale in Adults With Schizophrenia Spectrum Disorders.

Raudeberg R, Iverson GL · 2026 · Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists

Objective The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a brief neuropsychological screening battery that measures aspects of attention, immediate and delayed memory, and verbal and…

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Negative / Null Result ReportMedicine

Prospective evaluation of recombinant Herpes zoster vaccine in SSc: immunogenicity, safety and disease outcomes.

Luppino-Assad AP, Mello RP, Medeiros-Ribeiro AC et al. · 2026 · Rheumatology (Oxford, England)

Objectives To evaluate humoral immune response to recombinant zoster vaccine (RZV) in immunosuppressed patients with SSc compared with healthy controls, to identify factors influencing vaccine response and to assess RZV safety and impact…

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Negative / Null Result ReportMedicine

Correlation between lymphocyte counts and PD-L1 immune-related adverse events.

Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…

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Negative / Null Result ReportOpen accessMedicine

Effect of Structured Training on ICU Nurses' Knowledge-Based Competence in Ventilator-Associated Pneumonia Prevention in a Resource-Limited Setting: An Explanatory Sequential Mixed-Methods Study.

Yakubu YH, Saani MM · 2026 · Nursing open

Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…

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Negative / Null Result ReportOpen accessMedicine

Group-Based Medical Mistrust and Logistical Factors Influencing Rheumatology Clinical Trial Enrollment: A Single-Center Cross-Sectional Survey.

Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology

Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…

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Negative / Null Result ReportMedicine

Co-Occurring Substance Use and Psychiatric Disorders in Psychiatric Emergency Services: Suicidality, Substance Use, and Treatment Utilization.

Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis

Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…

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Negative / Null Result ReportMedicine

Novel measures of frontal plane knee wobbling predict anterior cruciate ligament injury in Japanese female basketball players: A prospective pilot study.

Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)

Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…

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Negative / Null Result ReportMedicine

Pain, respiratory symptoms, interpretation bias and death anxiety are associated with fear of disease progression in people with asthma.

Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology

Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…

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Negative / Null Result ReportMedicine

Examining links between somatosensation and cognition in children with hemiplegic cerebral palsy.

Hewitt KM, Bayliss DM, McLean BA et al. · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

Children with cerebral palsy (CP) are at increased risk of impaired somatosensation and cognition. Among children with hemiplegia, approximately three-quarters have impaired somatosensation and one-third have intellectual impairment. While…

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Negative / Null Result ReportOpen accessMedicine

Does Bone Quality Predict Pseudarthrosis, Subsidence, or Loss of Lordosis After Anterior Cervical Discectomy and Fusion? Minimum 5-Year Cohort Study.

Kim S, Park S, Ahn DK et al. · 2026 · Global spine journal

Study DesignRetrospective cohort study.ObjectivesTo determine whether preoperative cervical bone quality assessed by computed tomography Hounsfield units (CT HU) predicts pseudarthrosis, cage subsidence, or loss of cervical lordosis after…

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Negative / Null Result ReportMedicine

On how people describe paintings with mirrors.

Bertamini M, Lucia M, Diaz S et al. · 2025 · British journal of psychology (London, England : 1953)

Since antiquity humans have been fascinated by mirrors; yet, when asked to predict what is made visible in the reflection, or to interpret a scene with a mirror, observers make systematic errors. Many observers claim that a character in a…

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Negative / Null Result ReportMedicine

Patient-reported levels of pain and itch in hypertrophic scar before and after fractional ablative laser treatment.

Carreras JP, Carney BC, Lee D et al. · 2026 · Journal of burn care & research : official publication of the American Burn Association

Skin fibrosis, especially hypertrophic scars (HTS), remains understudied with few effective treatments. Studying HTS is challenging due to its natural tendency to improve over time, making it hard to separate intervention effects. This…

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Negative / Null Result ReportMedicine

Associations of spirituality and craving among individuals in substance use disorder treatment: A latent change score modeling approach.

Rabinowitz JA, Masyn K, Thomas N et al. · 2026 · Drug and alcohol dependence

Objective Using a latent change score modeling approach, we tested the bidirectional relationships between spirituality and craving during the first month of substance use disorder (SUD) treatment. Specifically, we examined whether higher…

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Negative / Null Result ReportMedicine

Evaluating day +90 donor chimerism as a prognostic marker of clinical outcomes among allogeneic hematopoietic cell transplant recipients who received myeloablative conditioning.

Jubas S, Collins K, Obara K et al. · 2026 · Transplantation and cellular therapy

Background Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for hematologic malignancies. However, relationships between donor chimerism and clinical outcomes remain poorly characterized. Objective The…

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