11,417 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Smeets M, Hutten E, Verboon P et al. · 2026 · Journal of psychosomatic research
Objective Previous studies have shown a positive relation between retrospectively measured loneliness and somatic complaints. This study investigated the relation between state loneliness and state somatic complaints as well as the…
View details →Dikici O, Aslanci ME, Alkan İ · 2026 · Ear, nose, & throat journal
ObjectiveTo assess the relationship between nasal septal deviation characteristics, sinonasal variations, and nasolacrimal duct (NLD) obstruction in primary Acquired Nasolacrimal Duct Obstruction (PANDO) and chronic dacryocystitis.MethodsA…
View details →Hare AM, Doo J, Pham TX et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Importance Comparative studies of prolapse outcomes among various routes of sacrocolpopexy (SCP) are limited. Objectives The objective was to examine the relationship between surgical route of SCP and anterior or posterior compartment…
View details →Yuan C, Zhou H, Wang A et al. · 2026 · International journal of psychology : Journal international de psychologie
Depression is frequently associated with problematic social media use (PSMU), yet evidence integrating day-to-day dynamics with longer-term temporal ordering remains limited. We conducted two studies to examine these associations. In Study…
View details →Bandura A, Mierzejewska M, Cytawa W et al. · 2026 · Cancers
Background: Oligometastatic non-small cell lung cancer (OMD NSCLC) represents a distinct clinical state with limited metastatic spread, where local ablative therapies (LAT) combined with systemic treatment may improve outcomes. Accurate…
View details →Burton M, Haft S, Fiskeaux M et al. · 2026 · Journal of anxiety disorders
Background Prolonged Exposure (PE) is an effective treatment for PTSD and clarification of mechanisms of change can inform training and continued improvements. Posttraumatic cognitions have been shown to predict subsequent symptom change…
View details →Tangili M, Mulder E, Jimeno B et al. · 2026 · Journal of evolutionary biology
Telomeres shorten with age, and telomere length (TL) can predict lifespan. In vitro studies have established that the shortest telomeres in the genome drive cellular senescence, but whether they also drive in vivo lifespan variation is…
View details →Ujihara M, Kawabori M, Nakajima M et al. · 2026 · Neurologia medico-chirurgica
Vagus nerve stimulation is an established treatment for refractory epilepsy, but predictors of treatment response remain unclear. Given that left-sided vagus nerve stimulation preferentially modulates the left thalamus and that epileptic…
View details →Jordan G, Stockinger K, Schiltz C et al. · 2026 · Communications psychology
Parenting is an emotion-eliciting experience that requires parents to navigate the dual demands of regulating their own and their children's emotions, drawing on regulatory strategies such as reappraisal and rumination. However, patterns…
View details →González DA, Wilson RS, Hemm J et al. · 2026 · NPJ Parkinson's disease
Loneliness is increasingly acknowledged as important in parkinsonism-related disorders. However, little is known about reciprocal longitudinal relationships between loneliness and parkinsonism. In this study, 3,099 community-based…
View details →Werenski H, Stratta R, McCracken E et al. · 2026 · Clinical transplantation
Introduction Despite well-established advantages of living-donor kidney transplantation (LDKT), LDKT growth has stagnated. Barriers to seeking a living donor include insufficient knowledge among candidates and discomfort discussing LDKT.…
View details →Cleary HL, Bernard MD, Davenport DL et al. · 2026 · Injury
Introduction There are no gold standard criteria for diagnosing blunt cardiac injury (BCI). While the combination of electrocardiogram (ECG) and serum troponin is considered the most sensitive screening method for those being considered…
View details →Ay L, Moik F, Füreder T et al. · 2026 · Hamostaseologie
Summary BACKGROUND: Patients with lung cancer are at high risk of developing venous thromboembolism (VTE). Although several risk assessment models (RAMs) for cancer-associated VTE exist, their performance in advanced lung cancer is…
View details →Nutor C, Dunlop AL, Brennan PA · 2026 · Journal of neurodevelopmental disorders
Background Maternal depression during pregnancy has been associated with increased risk of offspring autism spectrum disorder (ASD) - a highly heritable neurodevelopmental disorder. However, no study to date has taken into account maternal…
View details →Kunz V, Wald T, Gaenzle M et al. · 2026 · Cancer treatment and research communications
Introduction Frailty is a predictor of adverse outcomes in cancer patients, but its assessment in head and neck squamous cell carcinoma (HNSCC) patients is often limited due to time-consuming questionnaires being required for comprehensive…
View details →Basha MA, Elnaggar RK, Aloraini SM et al. · 2026 · Clinical rehabilitation
ObjectiveTo analyse physical fitness trajectories in paediatric burn survivors from discharge to 2 years post-injury, compare them with an age- and gender-matched control group, and identify baseline demographic and clinical…
View details →Youn C, Ford BN, Akeman E et al. · 2026 · Brain, behavior, and immunity
Behavioral activation therapy (BA) is an efficacious treatment for major depressive disorder (MDD). However, the neurobiological mechanism of action is unclear. The present study is a secondary, multimodal analysis of data from two BA…
View details →Boudouaia A, Mouas S, Mohamed AM et al. · 2026 · Acta psychologica
Understanding feedback is critical for students to cope with the complexities of multilingual development and transfer across languages. While it is crucial that students possess feedback literacy (FL) as a tool for engagement growth in…
View details →Scarlatescu E, Lisman T · 2026 · Journal of thrombosis and haemostasis : JTH
Background Diagnosing disseminated intravascular coagulation (DIC) in patients with chronic liver disease is challenging because cirrhosis-related hemostatic abnormalities mimic DIC laboratory features, leading to frequent overdiagnosis…
View details →Karhadkar MA, Friedman NP, Reynolds CA et al. · 2026 · Behavior genetics
Processing speed (PS), the rate at which an individual can perform basic cognitive tasks, and executive functions (EFs), cognitive abilities regulating thoughts and action, are key cognitive abilities related to important life outcomes. We…
View details →Lopes CLS, Rezende RQ, Ricachinevsky C et al. · 2026 · Pediatric pulmonology
Objective This study aimed to evaluate the frequency and severity of diaphragmatic atrophy in pediatric patients undergoing mechanical ventilation in the postoperative period of cardiac surgery. Methods A prospective cohort study was…
View details →Gallinat C, Wilhelm M, Moessner M et al. · 2026 · Comprehensive psychiatry
Background Trichotillomania (TTM) is a body-focused repetitive behavior disorder characterized by recurrent hair pulling and psychosocial impairment. Although theoretical models emphasize emotion regulation as a key mechanism in TTM, the…
View details →Wilson JD, Yee MY, Bureau JF · 2026 · Attachment & human development
Whereas attachment scholars argue that variations in crying in the SSP reflect the quality of child-parent relationships, temperament scholars contend that they primarily reflect temperamental traits. Few studies have examined this debate…
View details →Phung C, Wei K, Rizzi MD et al. · 2026 · International journal of pediatric otorhinolaryngology
Objective This study aims to assess whether an occurrence of acute sinusitis with orbital complications in childhood is associated with the development of long-term complications, including the development of chronic rhinosinusitis (CRS),…
View details →West Staples V, Angle E, Pickering A et al. · 2026 · Psychological trauma : theory, research, practice and policy
Objective The literature is mixed regarding the relationship between nightmares and suicide, with some suggesting that the variance in nightmares is explained by fear of sleep (FoS), insomnia, and/or obstructive sleep apnea (OSA). We add…
View details →Saul J, McGuinness L, Cooke M et al. · 2026 · Journal of autism and developmental disorders
Purpose Caregivers of children with neurodevelopmental conditions often experience poor mental wellbeing, which may be influenced by their child's behavioural or communicative profile. Few studies have focussed exclusively on caregivers of…
View details →Heddergott M, Pikalo J, Müller F et al. · 2026 · Viruses
While viral diseases of domestic cats ( Felis catus ) can threaten the recovery of the European wildcat ( Felis s. silvestris ), their epidemiology in wildcat populations remains poorly understood. Here, we analyzed 428 road-killed…
View details →Ishimoto K, Narita T, Sekine Y et al. · 2026 · Urologic oncology
Objective To evaluate whether the EV-ineligible criteria (EVITA) are associated with severe adverse events (AEs) and early treatment discontinuation in patients with locally advanced or metastatic urothelial carcinoma (la/mUC) treated with…
View details →Kristoffersen SF, Domazet SL, Pouwer F et al. · 2026 · Diabetes research and clinical practice
Aims We investigated longitudinal, bidirectional associations between objectively measured moderate to vigorous physical activity (MVPA), health-related quality of life (HRQoL), and emotional well-being (EWB) in individuals recently…
View details →Silkowski MK, Olson A, Asempah M et al. · 2026 · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Background The Impella 5.5 is increasingly used as a bridge to durable left ventricular assist device (dLVAD) implantation or heart transplantation, yet its effects on right ventricular (RV) hemodynamics remain incompletely characterized.…
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