11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Cleary HL, Bernard MD, Davenport DL et al. · 2026 · Injury
Introduction There are no gold standard criteria for diagnosing blunt cardiac injury (BCI). While the combination of electrocardiogram (ECG) and serum troponin is considered the most sensitive screening method for those being considered…
View details →Ay L, Moik F, Füreder T et al. · 2026 · Hamostaseologie
Summary BACKGROUND: Patients with lung cancer are at high risk of developing venous thromboembolism (VTE). Although several risk assessment models (RAMs) for cancer-associated VTE exist, their performance in advanced lung cancer is…
View details →Nutor C, Dunlop AL, Brennan PA · 2026 · Journal of neurodevelopmental disorders
Background Maternal depression during pregnancy has been associated with increased risk of offspring autism spectrum disorder (ASD) - a highly heritable neurodevelopmental disorder. However, no study to date has taken into account maternal…
View details →Kunz V, Wald T, Gaenzle M et al. · 2026 · Cancer treatment and research communications
Introduction Frailty is a predictor of adverse outcomes in cancer patients, but its assessment in head and neck squamous cell carcinoma (HNSCC) patients is often limited due to time-consuming questionnaires being required for comprehensive…
View details →Basha MA, Elnaggar RK, Aloraini SM et al. · 2026 · Clinical rehabilitation
ObjectiveTo analyse physical fitness trajectories in paediatric burn survivors from discharge to 2 years post-injury, compare them with an age- and gender-matched control group, and identify baseline demographic and clinical…
View details →Youn C, Ford BN, Akeman E et al. · 2026 · Brain, behavior, and immunity
Behavioral activation therapy (BA) is an efficacious treatment for major depressive disorder (MDD). However, the neurobiological mechanism of action is unclear. The present study is a secondary, multimodal analysis of data from two BA…
View details →Boudouaia A, Mouas S, Mohamed AM et al. · 2026 · Acta psychologica
Understanding feedback is critical for students to cope with the complexities of multilingual development and transfer across languages. While it is crucial that students possess feedback literacy (FL) as a tool for engagement growth in…
View details →Scarlatescu E, Lisman T · 2026 · Journal of thrombosis and haemostasis : JTH
Background Diagnosing disseminated intravascular coagulation (DIC) in patients with chronic liver disease is challenging because cirrhosis-related hemostatic abnormalities mimic DIC laboratory features, leading to frequent overdiagnosis…
View details →Karhadkar MA, Friedman NP, Reynolds CA et al. · 2026 · Behavior genetics
Processing speed (PS), the rate at which an individual can perform basic cognitive tasks, and executive functions (EFs), cognitive abilities regulating thoughts and action, are key cognitive abilities related to important life outcomes. We…
View details →Lopes CLS, Rezende RQ, Ricachinevsky C et al. · 2026 · Pediatric pulmonology
Objective This study aimed to evaluate the frequency and severity of diaphragmatic atrophy in pediatric patients undergoing mechanical ventilation in the postoperative period of cardiac surgery. Methods A prospective cohort study was…
View details →Gallinat C, Wilhelm M, Moessner M et al. · 2026 · Comprehensive psychiatry
Background Trichotillomania (TTM) is a body-focused repetitive behavior disorder characterized by recurrent hair pulling and psychosocial impairment. Although theoretical models emphasize emotion regulation as a key mechanism in TTM, the…
View details →Wilson JD, Yee MY, Bureau JF · 2026 · Attachment & human development
Whereas attachment scholars argue that variations in crying in the SSP reflect the quality of child-parent relationships, temperament scholars contend that they primarily reflect temperamental traits. Few studies have examined this debate…
View details →Phung C, Wei K, Rizzi MD et al. · 2026 · International journal of pediatric otorhinolaryngology
Objective This study aims to assess whether an occurrence of acute sinusitis with orbital complications in childhood is associated with the development of long-term complications, including the development of chronic rhinosinusitis (CRS),…
View details →West Staples V, Angle E, Pickering A et al. · 2026 · Psychological trauma : theory, research, practice and policy
Objective The literature is mixed regarding the relationship between nightmares and suicide, with some suggesting that the variance in nightmares is explained by fear of sleep (FoS), insomnia, and/or obstructive sleep apnea (OSA). We add…
View details →Saul J, McGuinness L, Cooke M et al. · 2026 · Journal of autism and developmental disorders
Purpose Caregivers of children with neurodevelopmental conditions often experience poor mental wellbeing, which may be influenced by their child's behavioural or communicative profile. Few studies have focussed exclusively on caregivers of…
View details →Heddergott M, Pikalo J, Müller F et al. · 2026 · Viruses
While viral diseases of domestic cats ( Felis catus ) can threaten the recovery of the European wildcat ( Felis s. silvestris ), their epidemiology in wildcat populations remains poorly understood. Here, we analyzed 428 road-killed…
View details →Ishimoto K, Narita T, Sekine Y et al. · 2026 · Urologic oncology
Objective To evaluate whether the EV-ineligible criteria (EVITA) are associated with severe adverse events (AEs) and early treatment discontinuation in patients with locally advanced or metastatic urothelial carcinoma (la/mUC) treated with…
View details →Kristoffersen SF, Domazet SL, Pouwer F et al. · 2026 · Diabetes research and clinical practice
Aims We investigated longitudinal, bidirectional associations between objectively measured moderate to vigorous physical activity (MVPA), health-related quality of life (HRQoL), and emotional well-being (EWB) in individuals recently…
View details →Silkowski MK, Olson A, Asempah M et al. · 2026 · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Background The Impella 5.5 is increasingly used as a bridge to durable left ventricular assist device (dLVAD) implantation or heart transplantation, yet its effects on right ventricular (RV) hemodynamics remain incompletely characterized.…
View details →Amihai L, Shahab S, Kligman T et al. · 2026 · Acta psychologica
Face-to-face conversations involve a rich array of social signals - facial expressions, gestures, vocal prosody, and gaze. While interpersonal mimicry of these signals has been extensively studied and shown to carry evaluative…
View details →Ishii T, Hagiwara Y, Matsuyama Y et al. · 2026 · BMC nephrology
Background In patients undergoing dialysis, increased salt intake is associated with an increased risk of cardiovascular disease (CVD) events, including a higher incidence of congestive heart failure. We calculated the estimated salt…
View details →Boutzoukas EM, Skop KM, Silva MA · 2025 · The Clinical neuropsychologist
Objective: Vestibular dysfunction is common following mild-to-moderate traumatic brain injury (TBI) and impacts quality of life. However, little is known regarding the persistence and stability of vestibular symptoms over time and their…
View details →Pavlacic JM, Walker JH, Andrews AR 3rd et al. · 2026 · Journal of clinical psychology
Introduction Poor self-rated health (i.e., perceived health status relative to same-aged individuals) is associated with elevated all-cause mortality. Research examining post-disaster self-rated health is limited but could inform disaster…
View details →Ryu JH, Kim S, Jeong KH et al. · 2026 · Health care for women international
Using data on causes of death(suicide) among older Korean women using data from the Korean Longitudinal Study of Aging (KLoSA) from 2006 to 2020, we examined changes in depression levels among 405 women over a period of three years or more…
View details →Lambey LD, Moffat SD · 2026 · Neuropsychologia
Active navigation involves direct control over movement and decision-making, whereas passive observation entails viewing another individual's exploration. Although active engagement is often assumed to benefit spatial learning, findings in…
View details →Muir MT, Noll K, Patel R et al. · 2026 · Journal of neurosurgery
Objective For patients with language-eloquent brain tumors, surgeons must maximize the extent of resection while minimizing neurological morbidity. Despite the extensive use of noninvasive brain mapping techniques, it remains unclear how…
View details →Noroozi Gilandehi S, Shoubash L, Leyendecker J et al. · 2026 · Journal of neurosurgery. Spine
Objective Although patients often report improvements in pain and functional capacity after endoscopic lumbar spine surgery, objectively measured real-life physical activity may differ from that reported. This multicenter prospective study…
View details →Yoo SW, Ryu DW, Oh Y et al. · 2026 · Journal of movement disorders
Background The thyroid gland receives sympathetic innervation. 123I-meta-iodobenzylguanidine (123I-MIBG) is a noradrenaline analog taken up by adrenergic nerve terminals. Although thyroid uptake can be seen on 123I-MIBG scintigraphy, its…
View details →Sullivan AJ, Whalen M, Cooper SE et al. · 2026 · Biological psychology
Fear conditioning research can provide insight into how individuals with clinically relevant traits learn to distinguish between threatening and safe stimuli. Prior studies have found higher anxiety symptoms to be associated with increased…
View details →Korbmacher M, Myhr KM, Wergeland S et al. · 2026 · Frontiers in neurology
Objective To replicate and extend recent findings, suggesting that higher serum alpha-linolenic acid (ALA) levels are associated with reduced disease activity and progression in multiple sclerosis (MS). Methods We reanalysed clinical trial…
View details →