11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Smoljan A, Koutnik-Abele S, Vladimirtsev D et al. · 2026 · Journal of integrative plant biology
Auxin, primarily indole-3-acetic acid (IAA), is a central regulator of growth and development in land plants, but its physiological role in chlorophyte algae remains unclear. Here, we show that exogenous IAA modulates growth in Chlorella…
View details →Mohy N, Sanaie S, Rahnemayan S et al. · 2026 · Beneficial microbes
Oxidative stress is a significant contributor to neuronal damage in multiple sclerosis (MS), marked by an imbalance in reactive oxygen species and antioxidant defences. Probiotics may modulate oxidative stress and improve antioxidant…
View details →Tan ZH, Yang LY, Hu YH et al. · 2026 · The American naturalist
AbstractSeasonal leaf dynamics in tropical rainforests directly affect canopy photosynthetic capacity and carbon assimilation. Although hypotheses such as water stress, solar light, and herbivore pressure have been proposed to elucidate…
View details →Handeland AH, Indelicato DJ, Engeseth GM et al. · 2026 · International journal of radiation oncology, biology, physics
Introduction Brainstem necrosis is a rare but serious toxicity following radiotherapy for pediatric brain tumors. In proton therapy (PT), concerns have emerged around elevated linear energy transfer (LET) and the relative biological…
View details →Kamionka SL, Sodemann M, Bilenberg N et al. · 2026 · Health (London, England : 1997)
Written information exchange is widely used to share information and coordinate care across services. Yet, its coordinating effects remain unclear. The aim of the study was to explore the textually mediated practices through which…
View details →Nichols JD, Hines JE, Hinz RL et al. · 2026 · Ecology
Experimental and observational studies of effects of fragmentation on biodiversity and population dynamics have produced mixed results, with some reviews concluding strong evidence of negative effects and others concluding small positive…
View details →Shida T, Hatanaka S, Ohta T et al. · 2026 · Geriatrics & gerontology international
Aim This study examined the association between plasma pentosidine concentrations-an advanced glycation end-product marker-and skeletal muscle morphometric indices, physical function, and sarcopenia among community-dwelling older adults…
View details →Liu P, Zhao S, Yao J et al. · 2026 · Acta parasitologica
Purpose Cultivation of Theileria annulata schizont-transformed cell lines typically relies on fetal bovine serum (FBS), limiting standardization. This study evaluated three serum-free media (SFMs) for the in-vitro cultivation of T.…
View details →Kim HH, Cragun J, DeScioli P · 2026 · Disasters
Researchers have argued that preventing disasters is more efficient than providing relief. Yet, previous scholarship has found that voters in the United States reward politicians more for relief than for prevention policies. It is unclear,…
View details →Gray SL, Liberman M, Onukwufor E et al. · 2026 · American journal of pharmaceutical education
Objectives Ageism remains a pervasive barrier to delivering high-quality health care to older adults. The objective of this scoping review is to describe studies on educational interventions aimed at improving the empathy and attitudes of…
View details →Tóth AJ, Kunszabó A, Szakos D et al. · 2026 · Waste management (New York, N.Y.)
Food waste in schools presents significant environmental, economic, and social challenges. This large-scale study investigates the effectiveness of an awareness-raising campaign aimed at reducing food waste in schools. The intervention…
View details →Todorovic L, Baumer J, Larsen H · 2026 · Addictive behaviors
This study examined the relationship between ADHD symptoms and problematic social media use (PSMU) and problematic gaming (PG) in a community sample of emerging adults. Cognitive deficits underlying ADHD - inhibitory control deficits,…
View details →Vasilyeva T, Kashirskaya N, Mukhina A et al. · 2026 · International journal of molecular sciences
The article presents a clinical case involving a patient with presumptive coexistence of two hereditary disorders, confirmed by molecular genetic analyses. Clinical evaluation of the proband, a 9-year-old girl, revealed features…
View details →Skriver C, Corn G, Viuff JH et al. · 2026 · European journal of epidemiology
Statins may have anti-cancer effects against breast cancer, but evidence regarding their influence on the risk of contralateral breast cancer (CBC) remains inconclusive. In this updated study, incorporating a larger sample, extended…
View details →Jin S, Huang J, Wang Y et al. · 2026 · Molecular and cellular biochemistry
Despite observed epidemiological associations, the direct causality between chronic kidney disease (CKD) and senile cataract remains unclear. This bidirectional Mendelian randomization (MR) study assessed the causal associations between…
View details →Luo J, Huang H, Shao W et al. · 2026 · Journal of affective disorders
Background Whether adolescent major depressive disorder (MDD) with psychotic features has a distinct peripheral metabolite signature remains uncertain. We compared targeted plasma neurotransmitter-related metabolites in psychotic MDD,…
View details →Imtiaz S, Russell C, Ali F et al. · 2025 · Substance abuse treatment, prevention, and policy
BACKGROUND: Decriminalization of possession of illegal drugs was implemented in British Columbia, Canada for a three-year period starting from January 31, 2023. As public sentiment played a large role in the outcome of a similar reform in…
View details →Elkhider O, Elshaikh O, Sharma A · 2026 · Cureus
Hemoglobin A1c (HbA1c) reflects average glycemia over approximately two to three months and is widely used for the diagnosis and monitoring of diabetes mellitus; however, discordant results may occur due to analytical interference, altered…
View details →Mulligan DJ, Grasso DJ, Greene CA et al. · 2026 · Research on child and adolescent psychopathology
The latent structure of posttraumatic stress symptoms (PTSS) in early childhood remains poorly understood. This study aimed to assess PTSS in young children, identify underlying latent constructs, and evaluate their construct validity.…
View details →Van de Bruaene C, Carbone F, Van den Houte K et al. · 2026 · Journal of neurogastroenterology and motility
Background/aims : The Leuven Postprandial Distress Scale (LPDS) is a validated patient reported outcome (PRO) measure for functional dyspepsia (FD)/postprandial distress syndrome (PDS) patients according to Rome III criteria. However,…
View details →Nuutinen V, Kaseva J, Lemola R et al. · 2026 · European Journal of Soil Science.
Deep burrowing earthworms Lumbricus terrestris can be abundant along subdrain trenches, creating macropores that may serve as preferential flow paths for particles and agrochemicals to subdrains. We examined L. terrestris abundance,…
View details →Khani E, Khoshbaten M, Jafarabadi MA et al. · 2026 · Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
Background and study aims Despite being the leading cause of liver-related mortality, the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) remains challenging. This study aimed to assess the effects of…
View details →McLeod A, Rullmann M, Hinderberger P et al. · 2026 · Neuroscience
A single nucleotide polymorphism in the brain derived neurotrophic factor (BDNF)-encoding gene leads to diminished BDNF signaling resulting from Val66Met and has been linked to obesity. Previous imaging studies regarding the impact of BDNF…
View details →Kastrati G, Sopaj F, Bytyqi V et al. · 2025 · Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
The study involved the determination of the concentrations of 11 potentially toxic elements (PTEs) in soil, honey, and pollen samples collected in the territory of Kosovo, followed by a statistical analysis. Inductively coupled…
View details →Alexander KN, Turner MS, Salazar JP et al. · 2025 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
Many adolescents experience peer victimization during this critical period for development. Emotion regulation strategies, including cognitive reappraisal and emotional suppression, can help adolescents cope with such experiences. Although…
View details →Ishiguro S, Guitard D, Saint-Aubin J · 2025 · Quarterly journal of experimental psychology (2006)
Semantic relatedness of items improves working memory performance. We targeted one type of semantic relatedness, semantic association. The beneficial effect of association is often explained by the spreading-activation process:…
View details →Güneş M · 2025 · Medicine
Magnesium has numerous important functions in human metabolism. Low magnesium level is a common finding in type 2 diabetes mellitus (T2DM) but the causes have not been sufficiently investigated. Smoking is associated with major health…
View details →Grant S, Goldberg E, Gadipudi A et al. · 2025 · Journal of racial and ethnic health disparities
Black transgender women report high levels of discrimination, which is associated with poor health outcomes. Some evidence suggests that intersectional discrimination-that is, interacting forms of marginalization related to one's real or…
View details →Bagby RM, Mortezaei A, McIntyre C et al. · 2026 · Journal of personality assessment
The Perth Alexithymia Questionnaire (PAQ) was developed to assess alexithymia as a multidimensional construct consistent with the attention-appraisal model. This study evaluated the hierarchical structure of the PAQ using Goldberg's…
View details →Ferreira-Correia A, Mnisi N, Harwood K et al. · 2025 · Applied neuropsychology. Adult
The Working Memory Questionnaire (WMQ) was developed to assess everyday difficulties associated with working memory (WM) impairments. This study evaluated the psychometric properties of the WMQ within a South African context. A…
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