11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Damianos JA · 2026 · Clinical biochemistry
Auto-brewery syndrome (ABS) is a rare disorder featuring episodes of intoxication caused by intestinal fermentation of dietary carbohydrates into ethanol. This article presents the case of a patient referred for evaluation of ABS. He…
View details →Canivez GL, Watkins MW, McGill RJ et al. · 2026 · Assessment
The Wechsler Adult Intelligence Scale-Fifth Edition (WAIS-5) latent factor structure was assessed using complementary hierarchical exploratory factor analyses (EFA) with the Schmid and Leiman procedure and confirmatory factor analyses…
View details →Yamamoto J, Nakamura K, Hayama H et al. · 2026 · Cardiology
Whether the mortality impact of ischemic stroke and major bleeding differs across left ventricular ejection fraction (LVEF) categories in patients hospitalized for acute heart failure (AHF) with atrial fibrillation (AF) remains uncertain.…
View details →Ricketts TA, Krivoshey R, Santos-Garrido J et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose The purpose of this study was to evaluate the effects of loudspeaker configuration and relative dialogue-to-background sound levels on subjective ratings of speech understanding and sound quality of recorded media for listeners…
View details →Jee J, Zhang J, Lavery JA et al. · 2026 · Cancer discovery
Real-world data suggest that SARS-CoV-2 mRNA vaccines, administered within 100 days of immune checkpoint inhibitor (ICI) treatment ("peri-ICI vaccination"), may improve ICI effectiveness through synergistic immune priming. In an…
View details →Maynart V, Menezes P, Batista C et al. · 2026 · Ear and hearing
Abstractobjectives The purpose of this experiment was to determine the effects of sequential sounds on cortical auditory evoked potentials and to investigate temporal masking. The study tested the hypotheses that forward masking reduces…
View details →Li X, Zhang Y, Chen S · 2026 · Journal of counseling psychology
This study examined how clients' outcome expectations (OE; belief about positive outcome of counseling session) was associated with working alliance and symptom relief longitudinally in a sample of Chinese beginning therapist trainees and…
View details →Peters EM, Quadri A, Aziz S et al. · 2026 · Journal of affective disorders
The purpose of this study was to examine the effects of two patient-level factors, episode duration and severity, on placebo response in antidepressant clinical trials. To do this we conducted a secondary analysis of seven 8-week,…
View details →Yan Z, Tian Y, Huang Y et al. · 2026 · Psychopathology
Introduction Distraction response style, neuroticism, and parental conflict have been linked to rumination in adolescents with subthreshold depression. However, whether these associations differ by gender remains unclear. Methods This…
View details →Howard L, Hawn S, Pitchford KD et al. · 2026 · Behavioral sciences (Basel, Switzerland)
The denial, concealment, or omission of disordered eating behaviors has received limited attention in the eating disorder literature, partly due to the lack of reliable and valid measures. This study re-examined the factor structure of the…
View details →Li Y, Chen R, Hou C et al. · 2026 · Medicine
We performed a 2-step Mendelian randomization (MR) study to investigate the associations of Fms-related tyrosine kinase 3 ligand (FLT3L) and phosphate levels with the risk of hypertrophic cardiomyopathy (HCM). Genetic instruments for 75…
View details →Aghaalikhani M, Rostami Abusaidi S, Azimi F et al. · 2026 · Journal of medical case reports
Background Osteosarcoma is the most common primary malignant bone tumor, typically affecting adolescents and young adults. While its development is often associated with rapid bone growth and genetic factors, the potential link between…
View details →Liu Y, Wei M · 2026 · Journal of the Optical Society of America. A, Optics, image science, and vision
Color matching functions (CMFs) play important roles in color specification, characterization, and reproduction. Though the CIE 1931 2° CMFs are widely used in practice, its well-known weaknesses and poor performance have motivated great…
View details →Rahal D · 2026 · Journal of health psychology
Although social support is related to better health, research is mixed regarding how social support relates to physiological systems including the parasympathetic nervous system. The present study assessed whether perceived parental and…
View details →Li YB, Zheng ZW, Zuo M · 2026 · BMC gastroenterology
Background Total body water (TBW) is an important indicator of fluid homeostasis and is closely related to various metabolic and chronic diseases. However, the relationship between TBW and gastrointestinal symptoms (stomach or intestinal…
View details →Liu P, Dang C, Liu J et al. · 2026 · Current medicinal chemistry
Introduction This study aimed to investigate the causal relationship and biological mechanism between oral contraceptives (OCs) and adverse pregnancy outcomes using Mendelian randomization (MR) methods. Methods We conducted a drug-target…
View details →Zadrożny Ł, Orlańska A, Ponto-Wolska M et al. · 2026 · European journal of dentistry
Objective This article aims to evaluate dental students' experiences, perceptions, and expectations related to training with virtual reality-based haptic simulators (VRHS) introduced into the preclinical and clinical dental curriculum.…
View details →Schmidt G, Dietsche S, Stoll K et al. · 2026 · Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
Objective To evaluate the psychometric properties of the German Birth Beliefs Scale (G-BBS) in a large sample of pregnant women in Germany, and its potential utility for women-centred birth counselling, and respectful maternity care.…
View details →Saengsin K, Jirattikanwong N, Wongyikul P et al. · 2026 · Journal of clinical medicine
Background/Objectives : Post-extubation stridor (PES) is common in pediatric critical care and may contribute to extubation failure, particularly in children with heart disease. Prophylactic corticosteroids are frequently used before…
View details →Espeche W, Minetto J, Cerri G et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension
Hypertensive disorders of pregnancy are a leading cause of maternal-fetal morbidity and mortality, with preeclampsia representing a major contributor to adverse outcomes. Ambulatory blood pressure monitoring (ABPM) has improved risk…
View details →Vollam S, Roman C, Santos M et al. · 2026 · JMIR medical informatics
Background Many studies have evaluated the use of wearable monitoring systems to improve patient safety in hospital. Although some have demonstrated effects on intensive care admissions, there remains little evidence of impact on patient…
View details →Qin X, Fan L, Tang Y et al. · 2026 · Archives of gynecology and obstetrics
Purpose The potential adverse effects of repeated freezing and thawing processes on embryos remain controversial. This study aimed to investigate the impact of repeated embryo cryopreservation by comparing preimplantation genetic testing…
View details →Koczur K, Blukacz M, Galbarczyk A et al. · 2026 · American journal of human biology : the official journal of the Human Biology Council
Objectives Microbiota of the urogenital tract is crucial for women's reproductive and sexual health and is largely dominated by Lactobacillus strains. A reduction of these bacteria within the vaginal microbial community has been linked to…
View details →Pongdee T · 2026 · Current allergy and asthma reports
PURPOSE OF REVIEW: Recent strategies to treat nonadvanced SM have focused on targeted therapies to inhibit mast cell activation and/or proliferation. Several investigational approaches are being explored to treat nonadvanced SM in this…
View details →McKenna VS, Gustin RL, Novak VD et al. · 2026 · Journal of voice : official journal of the Voice Foundation
Objective Acoustic outcomes documented following gender-affirming voice and communication therapy (GAVT) for vocal feminization often include measures of vocal pitch and resonance; however, it is likely that other aspects of speech and…
View details →Beatty-Wright JF, Hill PL · 2026 · The British journal of social psychology
Intergroup anxiety can undermine positive intergroup relations. This Registered Report presents two preregistered online studies testing a mental contrasting intervention to reduce intergroup anxiety towards Black individuals. Previous…
View details →An Z, Wang S, Zhang M et al. · 2026 · Cardiology research and practice
Background Three-vessel coronary artery disease (3V-CAD) often requires revascularization with either percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). The SYNTAX score is widely used for anatomical risk…
View details →Zhu F, Sun Y, Kuang D et al. · 2026 · Journal of medical Internet research
Background Children with inattentive attention-deficit/hyperactivity disorder (ADHD) often present with impairments in executive functions and fine motor skills in addition to core inattentive symptoms. However, evidence remains limited…
View details →Lee JC, Keller K, Lake AJ et al. · 2026 · Journal of economic entomology
Grapevine red blotch virus (GRBV) reduces grapevine vigor, delays grape ripening, reduces sugar content and quality of wines in North America and other continents. To date, the three-cornered alfalfa hopper, Spissistilus festinus, has been…
View details →Sanow S, Mantz M, Wissel H et al. · 2026 · Plant, cell & environment
Plant growth-promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium…
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