11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Li Y, Santer BD, Solomon S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Large volcanic eruptions and intense wildfires perturb Earth's atmospheric temperature. Understanding the climate response to such natural forcings is essential for obtaining reliable estimates of its response to anthropogenic greenhouse…
View details →Iribarren A, Obrutu O, Maughan J et al. · 2026 · American heart journal plus : cardiology research and practice
Background Caffeine, a nonselective adenosine A2 receptor antagonist, blunts adenosine-induced coronary hyperemia. Despite recommended abstinence before adenosine stress cardiac magnetic resonance imaging (CMRi), residual caffeine may…
View details →Sivanandam P, Syenina A, Chan YF et al. · 2026 · Communications medicine
Background Mucosally-applied aminoglycosides have demonstrated host-directed antiviral activity in preclinical models through induction of interferon-stimulated genes (ISGs). However, it remains unknown if systemically administered…
View details →Liu LT, Sun XS, Quan TT et al. · 2026 · Nature communications
Induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) is the standard treatment for locoregionally advanced nasopharyngeal carcinoma (LA-NPC); however, patients with a suboptimal response to IC, defined as detectable…
View details →Němá K, Kačúr P, Kozák T et al. · 2026 · Journal of functional morphology and kinesiology
Background: Operational performance in security-force settings depends on maintaining accurate motor-cognitive and shooting performance under acute physical strain. This descriptive pilot study examined pre-post performance patterns during…
View details →Rasmussen CA, Mink SB, Primdahl J et al. · 2026 · Musculoskeletal care
Introduction In recent years, the Ankylosing Spondylitis Performance Index (ASPI) has emerged as a new objective measure of physical function in patients with axial spondyloarthritis (axSpA). So far, only the relative interrater…
View details →Moabelo KC, Rauh R, Loots A et al. · 2026 · Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
We evaluated the performance of the FMDV 2.1 dry RT-rtPCR prototype assay (Tetracore) to detect foot-and-mouth disease virus (FMDV) in lymph nodes. Various masses (20-100 mg) of FMDV-negative lymph node tissue were homogenized, diluted,…
View details →Iannuzzi S, Müller M, Yu Y et al. · 2026 · Nature communications
The human immunodeficiency virus (HIV) infected approximately 1.1 million individuals in 2024. There is no effective vaccine or cure, and funding cuts in resource-limited settings threaten treatment access. Cost-effective and widely…
View details →Ho LYW, Lai CKY, Ng SSM · 2026 · Topics in stroke rehabilitation
Background The performance fatigue index provides objective measures for assessing the impact of fatigue on performance and it may be utilized for monitoring functional outcomes in individuals with stroke; however, its psychometric…
View details →Templado S, Almela-Rojo M, Barceló MD et al. · 2026 · Hearing research
Background Pigs are increasingly used as translational models for auditory research due to anatomical and physiological similarities with humans. However, normative auditory brainstem response (ABR) parameters in commercial pig breeds…
View details →Kavanagh EW, Joynt AT, Pion AR et al. · 2026 · JCI insight
Cystic fibrosis (CF) is a life-limiting genetic disorder caused by deleterious variants in the CFTR gene that results in altered mucus impairing the airway epithelia. Durable correction of these variants in airway cells remains a…
View details →Yin LX, Hidalgo CM, Bogan AW et al. · 2025 · JAMA otolaryngology-- head & neck surgery
Importance Circulating tumor human papillomavirus DNA (ctHPVDNA) is an important biomarker for the presence of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC), but little is known about early postoperative kinetics of ctHPVDNA…
View details →Chawana-Mutingwende TD, Ngara B, Mudadi LS et al. · 2026 · Journal of the International AIDS Society
Introduction Peripartum adolescent girls and young women (AGYW) with HIV have lower viral suppression compared to older women. But the recently introduced dolutegravir-based regimens and psychosocial peer motivation may improve viral…
View details →Giampaolo T, Liotard MG, Cadoré JL et al. · 2026 · Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Diagnosis of canine bacterial bronchopneumonia (bBP) is challenging and mostly based on bronchoalveolar lavage fluid (BALF) cytology and bacterial culture (BC) results. However, bacterial contamination of BALF is frequent, intracellular…
View details →Gleichenhagen J, Kaiser N, Brüning T et al. · 2026 · Journal of clinical laboratory analysis
Background Microsampling using filter cards for dried blood spots (DBS) and dried plasma spots (DPS) is a well-established technique offering practical advantages for blood collection and subsequent processing. For DBS/DPS, only a small…
View details →Kashiv P, Balwani M, Pasari AS et al. · 2026 · Cureus
Antibody-mediated rejection (ABMR) is conventionally defined by the presence of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSA), characteristic microvascular injury on allograft biopsy, and evidence of complement…
View details →Ifeh C, Allan E, Ndiaye A et al. · 2026 · Journal of food science
This study utilized collaborations with Senegalese women farmers to investigate the impact of lactic acid bacteria (LAB) fermentation of sorghum, baobab, and milk on nutritional and sensory qualities for plant-enriched yogurt. Using a…
View details →Arovah NI, Kushartanti W, Ambardini RL · 2026 · Rehabilitacion
Background and objective Nonspecific low back pain (NSLBP) is a prevalent musculoskeletal condition. This study examined the immediate effects of extracorporeal shockwave therapy (ESWT), ultrasound therapy (UST), and shortwave diathermy…
View details →Cherenack EM, Larson ME, Roach ME et al. · 2026 · Brain, behavior, and immunity
Background Limited research has examined the longitudinal interplay of depression, substance use, and immune dysregulation among men with HIV. Methods We analyzed longitudinal data from 100 men who have sex with men (MSM) living with HIV…
View details →Hoehne C, Rehling S, Schrenker J et al. · 2026 · Scientific reports
Preclinical simulation is essential for students to practice before clinical treatment. A low-cost 3D-printed model was developed with repositionable mobile maxillary anterior teeth to train periodontal splinting and evaluate learner…
View details →Tozawa R, Ishii N, Minamoto Y · 2026 · Cureus
Background Medial meniscus extrusion (MME) is a pivotal biomarker for knee osteoarthritis progression. Although ultrasonography offers a dynamic and cost-effective MME assessment, its clinical utility is often limited by the perceived high…
View details →Arslan SG, Gultekinler BD · 2026 · BMC sports science, medicine & rehabilitation
Background Force platforms are widely used to assess postural stability and vertical jump performance, yet their cost and limited portability restrict routine clinical and field-based use. The Meloq EasyBase force platform offers a…
View details →Strauss R, Wafula ST, Kobbe R et al. · 2026 · Open forum infectious diseases
We assessed baseline C-reactive protein (CRP) and procalcitonin levels in asymptomatic individuals from malaria-endemic West Africa. C-reactive protein remained unaffected by Plasmodium falciparum parasitemia, while procalcitonin (PCT) was…
View details →Loghin II, Vaţă A, Rusu ȘA et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives. Mother-to-child transmission (MTCT) or vertical transmission of human immunodeficiency virus (HIV) is largely preventable in settings where prevention of MTCT (PVT) strategies are consistently implemented.…
View details →Ware A, LaMountain J, White RC et al. · 2026 · Nature communications
The electromagnetic response of materials serves as the foundation for a broad range of vital applications, from imaging, to sensing, to classical and quantum communications. Here we demonstrate, theoretically and experimentally, a…
View details →Ajibola G, Nelson BS, Niesar A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Broadly neutralizing antibodies (bNAbs) are a promising treatment option for children with HIV-1, but their long-term impact on virologic, immunologic, and clinical outcomes is unknown. Methods The Tatelo Study investigated dual…
View details →· 2006
Data from well-conducted studies indicate that metformin levels in milk are low and infants would receive less than 0.5% of their mother's weight-adjusted dosage. Milk metformin levels are relatively constant during maternal metformin use,…
View details →Palenchar PM · 2026 · PloS one
Understanding how evolution shapes variability in gene expression is complicated by the interdependence of expression levels, expression variability, and evolutionary rates. Metrics that quantify variability independently of expression…
View details →Senise G, Bodega F, Porta C et al. · 2026 · Cells
Cigarette smoke is a major inducer of oxidative stress, promoting reactive oxygen species (ROS) accumulation and contributing to the pathogenesis of chronic obstructive pulmonary disease (COPD) and lung cancer. Heated tobacco products…
View details →· 2006
Infants receive citalopram in breastmilk, and it is detectable in low levels in the serum of some. The dosage that the infant receives and serum level achieved are probably related to the genetic metabolic capacity of the mother and…
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