11,316 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Scilipoti P, Callenmark M, Garmo H et al. · 2026 · European urology open science
Background and objective There are several methods for estimating prostate-specific antigen (PSA) doubling time (DT), and many men exhibit long periods of undetectable PSA below 0.1 ng/ml after radical prostatectomy (RP). We quantified…
View details →van Caelenberg E, Belpaire A, Dewaele D et al. · 2026 · Clinical and experimental dermatology
Background The Severity of Alopecia Tool (SALT) score is widely used. However, its inter- and intrarater reliability and smallest detectable difference (SDD) have not been rigorously evaluated. Objectives To determine the interrater and…
View details →Keshavarzi F, Arazpour M, Behzadipour S · 2026 · JMIR biomedical engineering
Background The application of spinal orthoses and local vibration in the treatment of hyperkyphosis is a developing concept. Further research is needed to determine the impact of leaf springs and local vibration techniques on the…
View details →McCaughan KJ, Danyluk MD, Kniel KE · 2026 · Applied and environmental microbiology
Tilling under is a method growers employ in an effort to remediate instances of widespread contamination in fields of crops, but its effectiveness with respect to specific pathogens remains poorly understood. This study had two overarching…
View details →Zhang S, Zhang H, Dong X et al. · 2026 · Frontiers in immunology
Background Radical cystectomy remains a standard curative treatment for muscle-invasive bladder cancer (MIBC). Bladder preservation after systemic therapy without immediate surgery remains investigational and requires careful patient…
View details →Swaine T, Bhagani S · 2026 · Current opinion in HIV and AIDS
Purpose of review Two-drug regimens (2DR) for antiretroviral therapy are increasingly being recommended for people living with HIV to reduce pill burden and reduce short and long-term toxicity. The exclusion of tenofovir and lamivudine or…
View details →Nicklas A, Rudari M, Reidow N et al. · 2026 · Plastic and reconstructive surgery. Global open
Background Postoperative wound healing remains a critical challenge, particularly in complex reconstructions such as free flap surgeries. Despite technical improvements, perfusion-related complications may cause partial flap loss.…
View details →Antaky CC, Leinbach IL, Plissner JH et al. · 2026 · PloS one
The use of rodenticides is a primary method for eradicating rodents from islands for conservation purposes. Rodenticide residue monitoring is often incorporated into rodent eradication project planning to understand the potential effects…
View details →Aderibigbe AS · 2026 · Poultry science
Despite increasing attention to broiler welfare, there is still limited information comparing physiological stress responses between fast-growing (FG) and slow-growing (SG) genotypes under evolving production conditions. Investigating this…
View details →Popiolek I, Hydzik P, Ciszowski K et al. · 2026 · Journal of clinical medicine
Background/Objectives: Alcohol-related liver disease (ALD) lacks widely adopted biomarkers that reflect disease activity and severity. High-mobility group box 1 (HMGB1), a damage-associated molecular pattern, has been implicated in ALD…
View details →Awadallah M, Singh A, Hale GL et al. · 2026 · Case reports in transplantation
Hepatitis E virus (HEV) infection is an increasingly recognized cause of acute and chronic hepatitis in immunosuppressed individuals, including solid organ transplant recipients. Although typically self-limited in immunocompetent hosts,…
View details →Yoon HJ, Kim GC, Nam SH · 2026 · Pathogens (Basel, Switzerland)
Background Oral candidiasis is an opportunistic infection caused by Candida albicans (C. albicans) , highlighting the need to evaluate candidate substances that ensure both antifungal efficacy and mucosal safety. This study aimed to assess…
View details →Carretero D, Giménez E, Pérez A et al. · 2026 · Enfermedades infecciosas y microbiologia clinica (English ed.)
Introduction Studies assessing SARS-CoV-2 antibodies and functional T-cell responses in hematological patients following receipt of a three-dose mRNA vaccine schedule have yielded conflicting results. Methods We conducted a retrospective…
View details →Chmielewska B, Marzec M, Szarejko I et al. · 2026 · Plant Science.
Root hairs, tubular extensions of the rhizodermal cells, facilitate nutrient uptake, yet their role in water acquisition remains debated and may be species- and soil-specific. To elucidate the genetic basis of root hair development and…
View details →Lee HL, Choi SM, Cho SH et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives: Head trauma (HT) has been suggested as a risk factor for Parkinson's disease (PD), but its impact on the motor and non-motor manifestations remains unclear. We investigated whether patients with early PD and a…
View details →Anand M, Kashyap R, Bhat P et al. · 2026 · BMC sports science, medicine & rehabilitation
Background Prolonged sedentary work is associated with hamstring tightness, reduced flexibility, and functional limitations among information technology (IT) professionals. Comparative evidence for static stretching and myofascial release…
View details →Willems R, Cappelletti M, Schüre JR et al. · 2026 · Scientific reports
Messenger ribonucleic acid (mRNA)-based vaccines delivered via lipid nanoparticles (LNP) were pivotal in managing the severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic. While mild systemic reactions are common after…
View details →Zaryczańska A, Sokołowska-Wojdyło M, Wilkowska A et al. · 2026 · Contact dermatitis
Background Chronic exposure to topical corticosteroids (TCS) in patients with atopic dermatitis (AD) may increase the risk of allergic contact dermatitis (ACD), which can mimic flares of the underlying disease and remain underrecognized.…
View details →Baneman E, Jacobs SE, Rana M et al. · 2026 · Clinical lymphoma, myeloma & leukemia
Background Cytomegalovirus (CMV) is an opportunistic pathogen that causes infection in certain immunocompromised hosts, but the risk of clinically significant CMV infection in patients with multiple myeloma (MM) is not well understood.…
View details →Srivastava A, Maienschein-Cline M, Pabalan A et al. · 2026 · Methods (San Diego, Calif.)
MicroRNAs (miRNAs) are promising biomarkers and therapeutic targets; however, reliable extracellular miRNA quantification by RT-qPCR depends on appropriate normalization, and no universal endogenous reference has been established. This…
View details →Chen C, Qualls WA, Xue RD et al. · 2026 · Journal of economic entomology
The sterile insect technique (SIT) is increasingly used as an alternative or supplemental tool in the integrated mosquito management toolbox to protect human health worldwide. SIT programs targeting mosquitoes such as Aedes aegypti (L.)…
View details →Buchkowski RW, Polussa A, Bradford MA · 2026 · Global change biology
Detecting changes in forest soil carbon stocks is critical for compiling national carbon budgets, yet remains challenging due to high spatial variability and relatively small temporal changes. Here, we use data from Canada's National…
View details →Oliveira YIL, Couto A, Sá PG et al. · 2025 · JBRA assisted reproduction
Objective To evaluate the association between antithyroid antibodies detectability and positivity and ovarian reserve. Additionally, we aimed to evaluate the correlation between TSH levels and parameters of ovarian reserve [anti-Mullerian…
View details →Requena-Tutusaus L, Anselmo I, Coll S et al. · 2026 · Journal of pharmacological and toxicological methods
Objectives Dried blood spot (DBS) micro-sampling is gaining prominence in anti-doping testing, particularly for the detection of erythropoietin-receptor agonists (ERAs) such as recombinant erythropoietin (rEPO). However, detecting…
View details →Yamagata F, Yoshihara K, Nannya Y et al. · 2026 · EJHaem
TP53 -altered myeloid neoplasms are associated with an extremely high risk of relapse even after allogeneic hematopoietic cell transplantation (allo-HCT), and the optimal pretransplant and posttransplant strategies remain undefined. We…
View details →Bienvenue I, Roux O, Coilly A et al. · 2026 · Liver international : official journal of the International Association for the Study of the Liver
Background & aims Liver transplantation (LT) is indicated for liver complications related to hepatitis B virus (HBV) infection: acute liver failure (ALF), decompensated cirrhosis or hepatocellular carcinoma (HCC). The present study aimed…
View details →Oliveira FADS, Santos LRH, Silva HAD et al. · 2026 · Journal of sport rehabilitation
Context Scapular dyskinesis is frequently associated with subacromial pain syndrome (SAPS), and clinicians increasingly use inertial sensors as a portable, low-cost option to assess scapular kinematics. However, the reliability of these…
View details →Kim D, Yang H, An J · 2026 · Cureus
Background Surgical stress alters cytokine concentrations, triggering systemic inflammatory responses and immune defense mechanisms. Interleukin-6 (IL-6) and interleukin-10 (IL-10) play important roles in perioperative inflammatory…
View details →Vlachou M, Solomakos N, Govaris A et al. · 2026 · Toxins
This study aimed to assess the occurrence and contamination levels of OTA in edible tissues of slaughtered pigs in Greece using high-performance liquid chromatography with fluorescence detection (HPLC-FD). Kidney, liver, muscle, and fat…
View details →Yun YJ, Moon C, Kim KH et al. · 2026 · Journal of clinical medicine
Background : Wearable powered gait orthoses offer a clinically flexible alternative to treadmill-based robotic systems, yet evidence on different device configurations matched to the site of neuromuscular impairment remains limited.…
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