Negative / Null Result ReportMedicine
Datta A, Katyayan I, Das KK et al. · 2025 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Parent Artery Occlusion (PAO) is a valid treatment choice in giant internal carotid artery (ICA) aneurysms of the cavernous segment when the preoperative balloon test occlusion (BTO) demonstrates an adequate cross circulation from the…
View details →Negative / Null Result ReportOpen accessMedicine
Stahlmann K, Reitsma JB, Zapf A · 2023 · Statistical methods in medical research
Most diagnostic studies exclude missing values and inconclusive results from the analysis or apply simple methods resulting in biased accuracy estimates. This may be due to the lack of availability or awareness of appropriate methods. This…
View details →Negative / Null Result ReportMedicine
Saber Tanha A, Hosseini S, Soltani E et al. · 2025 · Clinical nuclear medicine
Abstract A 47-year-old woman, recently diagnosed with breast cancer, underwent staging. A whole-body bone scan revealed an unexpected focal 99m Tc-MDP uptake in her right ovary. Extensive literature review suggested various malignant…
View details →Negative / Null Result ReportOpen accessMedicine
Dudnyk A, Tytarenko N, Lytvyniuk O et al. · 2026 · Therapeutic advances in infectious disease
Background Patients with multidrug-resistant tuberculosis (MDR-TB) receive treatment that is at least 20% less effective than drug-susceptible cases globally. Objectives The study evaluated the diagnostic accuracy of mfloDx MDR-TB assay…
View details →Negative / Null Result ReportMedicine
Mieites V, Fernández-Manteca MG, Santiuste Torcida I et al. · 2025 · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study explores the potential of conventional Raman spectroscopy and commonly used spectral analysis pipelines for rapid and straightforward assessment of degradation in serum samples resulting from storage delays. Serum samples from…
View details →Negative / Null Result ReportOpen accessMedicine
de Oliveira Castro Marques TR, Vidal SA, da Costa HA et al. · 2026 · Hematology, transfusion and cell therapy
Background Stroke, the most severe neurological complication of sickle cell disease, can result in irreversible sequelae and death. Transcranial Doppler combined with periodic blood transfusions reduces the chances of stroke by 90 %. In…
View details →Negative / Null Result ReportMedicine
Tu Y, Miao J, Wu Q et al. · 2025 · Respiratory medicine
Background Previous epidemiological studies have explored the association between obstructive sleep apnea (OSA) and osteoporosis (OP), with inconclusive results due to various biases. Herein, we sought to determine the causal association…
View details →Negative / Null Result ReportMedicine
Guarneri C, Reschini M, Pinna M et al. · 2024 · Journal of assisted reproduction and genetics
Purpose To evaluate whether a second biopsy, following a first diagnostic failure on blastocysts tested for preimplantation genetic testing for monogenic diseases (PGT-M), allows to obtain genetic diagnosis and to what extent this…
View details →Negative / Null Result ReportOpen accessMedicine
Su XY, Schroder A, Tse LA et al. · 2025 · BMC research notes
Background Sex hormones may play a role in the development of nasopharyngeal carcinoma (NPC), but the evidence is limited. Methods This case-control study collected information on sex hormonal and reproductive factors of 99 female incident…
View details →Negative / Null Result ReportOpen accessMedicine
Rosa ML, Bordignon C, Schuch JB et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives : Formalin-fixed paraffin-embedded tissue is widely used in pathology and molecular diagnostics, yet its variable quality can critically influence the accuracy of sequencing-based analyses. This study investigated…
View details →Negative / Null Result ReportOpen accessMedicine
Gopalaswamy R, Kumar N, Vashistha H et al. · 2023 · Frontiers in public health
Introduction Truenat MTB-RIF assay (Truenat), a nucleic acid amplification test (NAAT), is a real-time polymerase chain reaction (RT-PCR) chip-based assay that can detect Mycobacterium tuberculosis ( Mtb ) and rifampicin (RIF) drug…
View details →Negative / Null Result ReportMedicine
Tavelli R, Callens M, Grootaert C et al. · 2024 · Trends in Food Science & Technology.
Microplastics (MPs) contaminate the global marine and terrestrial ecosystems. This environmental contamination can enter the food chain, with MPs found in drinking water, fishery products and other food categories. Consequently, ingestion…
View details →Negative / Null Result ReportMedicine
Juutilainen J, Khan MW, Naarala J et al. · 2024 · Occupational and environmental medicine
Objectives Studies assessing the association of adult cancers with extremely low frequency (ELF) magnetic fields (MF) have provided inconclusive results, probably affected by limitations such as low exposure levels, confounding and various…
View details →Negative / Null Result ReportOpen accessMedicine
Hernández-Cuellar E, Tsuchiya K, Medina-Contreras O et al. · 2025 · Journal of clinical medicine
Background/Objectives : Sepsis is a life-threatening condition characterized by an uncontrolled immune response due to systemic infections. It is responsible for millions of deaths worldwide. Although inflammasomes play an important role…
View details →Negative / Null Result ReportMedicine
Nielsen MK, Bartholdy ID, Kristensen KS et al. · 2025 · Veterinary parasitology
Equine strongylids are ubiquitous and can cause severe health issues. Anthelmintic resistance is widely common in cyathostomin parasites, and recent studies have documented increasing incidence of resistance to the macrocyclic lactone drug…
View details →Negative / Null Result ReportMedicine
MacCarrick G, Aradhya S, Bailey M et al. · 2024 · American journal of medical genetics. Part A
Molecular genetics enables more precise diagnoses of skeletal dysplasia and other skeletal disorders (SDs). We investigated the clinical utility of multigene panel testing for 5011 unrelated individuals with SD in the United States…
View details →Negative / Null Result ReportOpen accessMedicine
Karvasarski E, Park J, Savaris S et al. · 2026 · CJC open
Background Resting hemodynamic assessment of suspected pulmonary hypertension (PH) in older adults with cardiovascular risk factors may not effectively discriminate pre-capillary from post-capillary disease. Exercise right-heart…
View details →Negative / Null Result ReportMedicine
Crabtree D, Seidler K, Barrow M · 2025 · Clinical nutrition ESPEN
Background and aims Epidemiological studies have associated reduced bacterial diversity and abundance and food allergy. This mechanistic review investigated the link between gut dysbiosis and food allergy with a focus on the role of…
View details →Negative / Null Result ReportMedicine
Nohales M, Coello A, Martin A et al. · 2023 · Journal of assisted reproduction and genetics
Purpose To investigate whether embryo rebiopsy increases the yield of in vitro fertilization (IVF) cycles. Methods Retrospective study including 18,028 blastocysts submitted for trophectoderm biopsy and preimplantation genetic testing for…
View details →Negative / Null Result ReportMedicine
Cummings M, Madhavan S · 2024 · Experimental brain research
Ischemic Conditioning (IC) is a procedure involving brief periods of occlusion followed by reperfusion in stationary limbs. Blood Flow Restriction with Exercise (BFR-E) is a technique comprising blood flow restriction during aerobic or…
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Salgotra M, Bharti N, Sinha V et al. · 2024 · Journal of pharmacy & bioallied sciences
Introduction Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective…
View details →Negative / Null Result ReportMedicine
Linthorst J, Nivard M, Sistermans EA · 2024 · Cell reports
The properties of cell-free DNA (cfDNA) are intensely studied for their potential as non-invasive biomarkers. We explored the effect of common genetic variants on the concentration and fragmentation properties of cfDNA using a genome-wide…
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Pham YT, Nguyen BN, Nguyen TG et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Iron is one of the essential elements for human life. Prior studies provided inconclusive results about the association between dietary iron intake and gastric cancer risk. We determined the association between dietary iron…
View details →Negative / Null Result ReportMedicine
Pardi C, Hellberg Å, Isakson P · 2024 · Blood transfusion = Trasfusione del sangue
Background The Rh blood group system is highly complex, polymorphic, and immunogenic. The presence of RHD gene variants in RhD negative pregnant women is a challenge in fetal RHD genotyping as it may influence the antenatal management of…
View details →Negative / Null Result ReportOpen accessMedicine
Boyarchuk O, Volianska L, Smashna O et al. · 2024 · Frontiers in genetics
Introduction Developmental delay (DD) in children is often caused by genetic abnormalities, which are challenging to diagnose due to the vast genetic variability. Methods This study presents a detailed analysis of whole-exome sequencing…
View details →Negative / Null Result ReportOpen accessMedicine
Gutowska A, Bohdan M, Radtke-Łysek A et al. · 2026 · The American journal of case reports
BACKGROUND Cardiac myxomas are the most common primary cardiac tumors in the general population but are exceedingly rare in orthotopic heart transplant recipients. Fewer than 5 cases have been reported. Their pathogenesis in the setting of…
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Mattke S, Jun H, Hanson M et al. · 2024 · The journal of prevention of Alzheimer's disease
Introduction As treatments for secondary prevention of Alzheimer's disease (AD) are being studied, concerns about their value for money have appeared. We estimate cost-effectiveness of a hypothetical screening and prevention program.…
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Harjunen L, Östman K, Pohl P · 2025 · Disability and rehabilitation
Purpose Ronnie Gardiner Method (RGM) is a music-based movement therapy that has long been used within rehabilitation. There is a need to (1) identify the scope of the use of RGM, (2) explore potential benefits, (3) examine qualitative…
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Portillo-Gallo JH, Sánchez-González JM, Saldaña-Cruz AM et al. · 2026 · Current issues in molecular biology
Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have…
View details →Negative / Null Result ReportOpen accessMedicine
Beissat K, Lattard V, Picard-Meyer E et al. · 2025 · PloS one
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range of animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence of new variants has…
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