Negative / Null Result ReportOpen accessMedicine
Sieborg J, Maul JT, Wu JJ et al. · 2025 · Acta dermato-venereologica
Biosimilars are designed to be analogous to the biologic originators. However, comprehensive comparisons between biosimilars are limited and lacking for patients with psoriasis. This study's objective was to compare 1-year drug survival of…
View details →Negative / Null Result ReportMedicine
Hossain SJ, Tofail F, Mehrin SF et al. · 2023 · Pediatrics
Background and objectives Previously, in 30 Bangladeshi villages, 2 groups of children with iron-deficiency anemia (IDA) and nonanemic (NA) iron sufficiency aged 6 to 24 months participated in 2 parallel cluster randomized controlled…
View details →Negative / Null Result ReportOpen accessMedicine
Bingöl G, Jesurasa S, Stroethoff M et al. · 2025 · Frontiers in cardiovascular medicine
Remote ischemic preconditioning (RIPC) has been shown in several experimental studies as an organ protective procedure against ischemic injury, but the implementation of RIPC into routine clinical practice has so far failed due to…
View details →Negative / Null Result ReportOpen accessMedicine
Mayer L, Lichtblau M, Furian M et al. · 2025 · Journal of the American Heart Association
Background Exposure to high altitude triggers hypoxic pulmonary vasoconstriction with a rise in pulmonary artery pressure (PAP). This may lead to symptomatic pulmonary hypertension with impaired right heart function and exercise capacity.…
View details →Negative / Null Result ReportOpen accessMedicine
López-de la Rosa A, Díez-Montero C, Martínez-Plaza E et al. · 2024 · Ophthalmology and therapy
Introduction Characterizing lens thickness (LT) in patients with cataracts is important for better understanding the lens aging process and for designing new intraocular lens power formulas. This study aimed to analyze the influence of…
View details →Negative / Null Result ReportMedicine
Fitzgerald LS, Reynoso Spurrier CS, Lau NJ et al. · 2025 · American journal of physiology. Endocrinology and metabolism
Mitochondria are key regulators of metabolism and ATP supply in skeletal muscle, while circadian rhythms influence many physiological processes. However, whether mitochondrial function is intrinsically regulated in a circadian manner in…
View details →Negative / Null Result ReportMedicine
Fernández-Ruiz M, Sánchez Moreno B, Santiago Almeda J et al. · 2023 · Transplant infectious disease : an official journal of the Transplantation Society
Previous studies have suggested that exposure to statins confers a protective effect in bloodstream infection (BSI) due to the anti-inflammatory and immunomodulatory properties attributed to these lipid-lowering drugs. Scarce evidence is…
View details →Negative / Null Result ReportOpen accessMedicine
Vilk Ayalon N, Omer Vilk N, Sompolinsky Y et al. · 2026 · Reproductive health
BACKGROUND: Frozen embryo transfer (FET) is widely used due to its safety and effectiveness. However, it has been associated with an increased risk of large for gestational age (LGA) infants. Proposed mechanisms include effects of embryo…
View details →Negative / Null Result ReportOpen accessMedicine
Agudelo LR, Yarmush G, Kumar S et al. · 2025 · Biology
Accelerating healing is a clinical goal in both acute and chronic non-healing skin wounds. We leveraged the public Recon database, which seeks to aggregate all of the metabolic pathways in the human body, to uncover whether increasing the…
View details →Negative / Null Result ReportMedicine
Sandoval-Alarcón S, Bäumle R, Castellucci HI · 2025 · Applied ergonomics
Dentists face various occupational demands that heighten their risk of developing work-related musculoskeletal disorders (WMSDs), including prolonged static postures, repetitive movements, unsuitable dental instruments, extended work…
View details →Negative / Null Result ReportOpen accessMedicine
Warren WG, Papagianni EP, Hale E et al. · 2022 · Frontiers in pharmacology
Endocannabinoid transmission is emerging as a target for treating anxiety-related disorders, given its regulation of fear extinction. Boosting anandamide levels via inhibition of its metabolism by fatty acid amide hydrolase (FAAH) can…
View details →Negative / Null Result ReportOpen accessMedicine
Khalid E, Vijayan MM · 2025 · Frontiers in endocrinology
Introduction Although the Crh-Crhr1 system is the proximal trigger for the stressor-induced corticosteroid release, its role in initiating the fight-or-flight response to an acute stressor is unclear. We hypothesized that the Crh-Crhr1…
View details →Negative / Null Result ReportOpen accessMedicine
Ouerghi N, Abassi W, Jebabli N et al. · 2026 · Sports (Basel, Switzerland)
The study investigated the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness, hormonal, and psychological markers in adolescents. Twenty-eight healthy male adolescents were randomized to a HIIT group or a…
View details →Negative / Null Result ReportOpen accessMedicine
Toledo FV, Meletti JFA, Silva LMC et al. · 2026 · Brazilian journal of anesthesiology (Elsevier)
Introduction Surgery remains one of the most important treatments for breast cancer. In this context, the quality of postoperative recovery has become a key concern. Adequate control of acute pain is essential to optimize patient comfort…
View details →Negative / Null Result ReportMedicine
Salihu AT, Usman JS, Hill KD et al. · 2023 · Experimental brain research
The ability to control balance and prevent falls while carrying out daily life activities may require a predominantly controlled (cognitive) or automatic processing depending on the balance challenge, age, or other factors. Consequently,…
View details →Negative / Null Result ReportOpen accessMedicine
Tatsuoka Y, Zembrzuski KJ, Natalini JG et al. · 2025 · Journal of clinical medicine
Background: Primary graft dysfunction (PGD) is the leading cause of early mortality after lung transplantation. Albumin is commonly used during lung transplantation to maintain intravascular volume while minimizing total intravenous fluid…
View details →Negative / Null Result ReportOpen accessMedicine
Berge M, Hultgren O, Hugosson S et al. · 2026 · Scientific reports
There are large variations in how individual patients respond to allergen immunotherapy (AIT) against grass and/or birch allergy. There are currently no reliable biomarkers to predict which patients are likely to benefit from the…
View details →Negative / Null Result ReportOpen accessMedicine
Mariani C, Al Dababsekh A, Carta F et al. · 2025 · Medicina (Kaunas, Lithuania)
Background and Objectives : Hemostasis during thyroid surgery is crucial to avoid postoperative complications, particularly hematoma, which can cause life-threatening airway compromise. Arista™ AH, a plant-based absorbable hemostatic…
View details →Negative / Null Result ReportOpen accessMedicine
Jobson I, Vo NTN, Kujawinski E et al. · 2025 · Bioelectronic medicine
Background In glioblastoma (GBM) therapy research, tumour treating fields by the company Novocure™, have shown promise for increasing patient overall survival. When used with the chemotherapeutic agent temozolomide, they extend median…
View details →Negative / Null Result ReportOpen accessMedicine
Johnson KV, Steenbergen L · 2025 · Npj mental health research
The burgeoning field of the microbiome-gut-brain axis has inspired research into how the gut microbiome can affect human emotion. Probiotics offer ways to investigate microbial-based interventions but results have been mixed, with more…
View details →Negative / Null Result ReportOpen accessMedicine
Nimkulrat SD, Wagner MR, Waters BJ et al. · 2025 · Scientific reports
RNA binding proteins (RBPs) are increasingly being recognized as important regulators of pancreatic β cells' identity and function. We identified the poly-A binding RBP, CPEB1, as a potential new regulator linked to β cell failure in…
View details →Negative / Null Result ReportOpen accessMedicine
Ó Dúinín E, Steopan JK, Kessler K et al. · 2025 · Scientific reports
We investigated the effects of cognitive training with transcranial random noise stimulation (tRNS) applied to the intraparietal sulcus (IPS) or dorsolateral prefrontal cortex (DLPFC) on improving a multidirectional number line estimation…
View details →Negative / Null Result ReportOpen accessMedicine
Cesanelli L, Venckunas T, Minderis P et al. · 2026 · Antioxidants (Basel, Switzerland)
Background/Objectives : This study aimed to evaluate the effects of short-term broccoli powder supplementation on metabolically demanding exercise performance, muscle power, and blood lactate recovery. It also investigated broccoli…
View details →Negative / Null Result ReportOpen accessMedicine
Turton S, Hawkins PCT, Muller-Pollard C et al. · 2025 · Psychopharmacology
Rationale It is hypothesised that modulation of striatal dopaminergic signalling plays a key role in the rewarding effects of opioids. The monetary incentive delay (MID) task is a functional magnetic resonance imaging (fMRI) paradigm used…
View details →Negative / Null Result ReportMedicine
Farhat MR, Jacobson KR · 2024 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Active case finding leveraging new molecular diagnostics and chest X-rays with automated interpretation algorithms is increasingly being developed for high-risk populations to drive down tuberculosis incidence. We consider why such an…
View details →Negative / Null Result ReportOpen accessMedicine
Yokoyama M, Kaida R, Miyamoto K et al. · 2024 · Plant biotechnology (Tokyo, Japan)
α-Ketol octadecadienoic acid (KODA), an oxylipin, is generated from linolenic acid by 9-specific lipoxygenase, while jasmonic acid is ultimately synthesized from the same linolenic acid by 13-specific lipoxygenase. KODA has a unique action…
View details →Negative / Null Result ReportOpen accessMedicine
Queiroz MG, Tobar KDL, Damazo AS et al. · 2026 · International journal of environmental research and public health
This randomized crossover study aimed to evaluate the effect of a single session of aerobic exercise on 24 h ambulatory blood pressure (BP) and heart rate variability (HRV) in young adults with a family history of hypertension, FHH +…
View details →Negative / Null Result ReportOpen accessMedicine
Winter AL, Peter M, Thunell E et al. · 2026 · Neural plasticity
Absence of sensory input is associated with alterations in brain morphology; mainly in or near cerebral regions normally devoted to processing of the missing sense. However, multiple recent studies demonstrate that the only consistent…
View details →Negative / Null Result ReportMedicine
Chen P, Lv J · 2024 · Nephrology (Carlton, Vic.)
This mini-review explores glucocorticoids, mycophenolate mofetil (MMF), and hydroxychloroquine (HCQ) in IgA nephropathy (IgAN). It discusses conflicting findings from pivotal trials like TESTING and STOP-IgAN regarding glucocorticoid…
View details →Negative / Null Result ReportOpen accessMedicine
Alam KA, Martí-Solans J, Schall D et al. · 2026 · ACS chemical neuroscience
Voltage-gated potassium channel KCNQ1 (Kv7.1) plays a critical role in electrical excitability in the heart, gut, and brain. Together with the auxiliary subunit KCNE1, KCNQ1 generates a slow delayed rectifier current ( I Ks ) that is…
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