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Browse the failure-mode index

11,416 real negative results, null findings, and replication failures in Medicine · Negative / Null Result Report. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Comparison of oncological outcomes between wedge resection and segmentectomy for T1a/bN0M0 non-small-cell lung cancer: a population-based retrospective cohort study.

Zhang Z, Lian H, Huang L et al. · 2026 · International journal of surgery (London, England)

Background Sublobar resection, including wedge resection (WR) and segmental resection (SR) has been considered for early-stage non-small-cell lung cancer (NSCLC). However, the optimal sublobar approach continues to be a subject of…

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Negative / Null Result ReportOpen accessMedicine

No evidence that averaging voices influences attractiveness.

Ostrega J, Shiramizu V, Lee AJ et al. · 2024 · Scientific reports

Vocal attractiveness influences important social outcomes. While most research on the acoustic parameters that influence vocal attractiveness has focused on the possible roles of sexually dimorphic characteristics of voices, such as…

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Negative / Null Result ReportOpen accessMedicine

Parietal theta burst TMS does not modulate bistable perception.

Schauer G, Grassi PR, Gharabaghi A et al. · 2024 · Neuroscience of consciousness

The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential transcranial magnetic stimulation studies have revealed differences in conscious perception following parietal…

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Negative / Null Result ReportOpen accessMedicine

The relationship between aging out of the special supplemental nutrition program for women, infants, and children assistance and weight status in kindergarten.

Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports

Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…

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Negative / Null Result ReportOpen accessMedicine

Biomechanical Factors Associated with Intraindividual Differences in Running Economy Across Advanced Footwear Technology Models in Long-Distance Runners.

Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open

Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…

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Negative / Null Result ReportOpen accessMedicine

Alterations of brain network topology and structural-functional connectivity coupling in noise-induced hearing loss based on macroscopic scale.

Wang A, Bao X, Wang C et al. · 2025 · Frontiers in neuroscience

Objective To investigate the changes in the global attributes of structural connectivity (SC) and functional connectivity (FC) graph theory, as well as the coupling topological structure of the whole brain SC-FC in patients with…

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Negative / Null Result ReportOpen accessMedicine

Association of cardiovascular risk scores with coronary plaque and its progression among individuals with family history of coronary artery disease.

Soh CH, Nerlekar N, Whitmore K et al. · 2026 · American journal of preventive cardiology

Background Multiple cardiovascular (CV) risk assessment scores can predict CV events. The current trend towards assessing atheroma has led to these scores being used to identify patients who might benefit from coronary plaque imaging.…

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Negative / Null Result ReportOpen accessMedicine

<i>TNF-α</i> rs1800629 Polymorphism in Vietnamese COPD Patients: Exploratory Evidence for Recessive Protective Association and Clinical Correlates.

Nguyen HM, Le DHH, Ho TTH et al. · 2026 · The application of clinical genetics

Background Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The TNF-α rs1800629 (-308G/A) polymorphism is an influential factor in disease pathogenesis. However, its association is inconsistent…

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Negative / Null Result ReportOpen accessMedicine

Kava consumption and the rise of sociopolitical complexity in Oceania.

Hrnčíř V, Sheehan O, Claessens S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America

Humans have been using psychoactive substances for millennia, despite their potential negative health and social consequences. According to some scholars, our craving for mind-altering drugs is an evolutionary mistake-a hijacking of our…

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Negative / Null Result ReportOpen accessMedicine

Restricting facial mimicry does not impair emotion recognition or influence the evaluation of human affect vocalizations and instrumental sounds.

Wołoszyn K, Hohol M, Winkielman P · 2026 · Scientific reports

The embodied simulation approach predicts that restricting facial movements disrupts emotion recognition. Such effects have been reported for facial and whole-body emotional expressions, but findings remain inconsistent, and it is unclear…

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Negative / Null Result ReportOpen accessMedicine

Object relations are processed with, but not without, awareness.

Palgi S, Bester-Arest T, Faivre N et al. · 2025 · Neuroscience of consciousness

The scope of unconscious integration is widely debated. Here, we examined this question, focusing specifically on deciphering the relations between two associatively related objects, in a set of five behavioral and electrophysiological…

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Negative / Null Result ReportOpen accessMedicine

Does Conflictual Dialogue Improve a Story?

Berks JW, Williams MN · 2026 · Europe's journal of psychology

According to creative writing experts, adding conflict to dialogue improves story quality and audience reaction to that story. This idea draws from the widely held theory that conflict is vital for dramatic stories. Yet despite conflict's…

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